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The map label for this gene is fbp

Identifier: 163844991

GI number: 163844991

Start: 844542

End: 845564

Strand: Reverse

Name: fbp

Synonym: BSUIS_B0865

Alternate gene names: 163844991

Gene position: 845564-844542 (Counterclockwise)

Preceding gene: 163844992

Following gene: 163844990

Centisome position: 60.36

GC content: 59.63

Gene sequence:

>1023_bases
ATGACATTGGTAGGTAATTTTTCTCCTCTGGTTCTGGTTGGCGATAGCGATCGCGTGGAAGCCGAAACCGTCGGCGCCTA
TCTCGATGGCTGGGCCGGGCATGATAAAGTGCGGCTCGCCACGGCCAACGCAATCAAGGCTATTCTTTCCGGTGCGGGCA
GGCTTGTGGGCCGTATTGCGCGCGGATATCTGCCGGGCGATCCCGGCAAGCTTGTCGGGGTCAATAGTGACCAGGATCAG
CAAAAGAGCATTGATGTCGGATCGCACAATCTATTCGTTGAGCTTCTGATTGCCGCTGGCGTGGCTTCCATTCTTTCCGA
AGAAGCGGATCTGCCTGTAGCGGGCAAGGCCGATGGGCTGGTGGCTGTCGCCATCGATCCGCTCGACGGTTCGGGCAATG
TGGGCCTCGGCGCGCCGCTTGGCACGATTTTCTCGATTTTCCCCGCCGATGTGGAAGAACCCTTCCTCCAGCCCGGCAAT
CGCCAGATTGCCGCTGGCTATGTTTCATACGGCAATTCGGTCGATCTCGGCTTTTCGGTTGGGGAGGGCGTGATCTTCGC
GACGCTTGATCCGGTGAGCGGCCAGTTCCACATTACGCGGCGCAATGTGAAGCTGCCGGAACGCACATCCGATCTGGCGT
TCAACGCCTCGGTCCAGCGGCATCTGTCGGCGGGCATGCAGGCCTATGTCAACGACGCCTTCCTTGGCAAGGATGGTCCG
CGCGGGCGTAACTTCAACATGCGCTGGCTCGGCGCTGCGGTGGGCGACATGCACCGCATCATGCAGCGCGGCGGCCTGTT
TTTCTATGTGAACGACAGCCGCCCCGGCTATGAGAAGGGCCGCCTGCGGCTGGTTTACGAAGCCAATCCGATTGCTTTCC
TCGCCCGTGAAGCGGGGGGCAAGGCGACGGATGGTTCGAGACCTATTCTCGATATCGTTCCGCAAACCTATCACGAGCGC
AGTGCGCTGGTGTTCGGCGTGGCCGAAGAGGTGGATATCCTCGGCGAATATTTCGTGAAATAA

Upstream 100 bases:

>100_bases
TCGCCCCGCCCGTATTCGATAAGCTGCAACGTGTACAATGCATTCGCGTGCTTTCCCTCGATACCGCGCATCTTGCCGGG
GATTTTCAGGAGCAGGGCCA

Downstream 100 bases:

>100_bases
CCTGATCTCACATCGACTAGGAGGCTAGAAATGGCGCGCATTACGCTGCGGCAATTGCTCGATCACGCCGCTGAAAAGGG
TTACGGCGTTCCGGCATTCA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQ
QKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGN
RQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGP
RGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHER
SALVFGVAEEVDILGEYFVK

Sequences:

>Translated_340_residues
MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQ
QKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGN
RQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGP
RGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHER
SALVFGVAEEVDILGEYFVK
>Mature_339_residues
TLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQQ
KSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNR
QIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGPR
GRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHERS
ALVFGVAEEVDILGEYFVK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=298, Percent_Identity=34.5637583892617, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI189083692, Length=299, Percent_Identity=33.1103678929766, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI16579888, Length=299, Percent_Identity=33.1103678929766, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1790679, Length=235, Percent_Identity=40, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17508131, Length=344, Percent_Identity=31.9767441860465, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6323409, Length=262, Percent_Identity=34.7328244274809, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19921562, Length=269, Percent_Identity=35.3159851301115, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI45550998, Length=269, Percent_Identity=35.3159851301115, Blast_Score=154, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_BRUA1 (B2SAG4)

Other databases:

- EMBL:   CP000888
- RefSeq:   YP_001932297.1
- ProteinModelPortal:   B2SAG4
- SMR:   B2SAG4
- GeneID:   6326004
- GenomeReviews:   CP000888_GR
- KEGG:   bmc:BAbS19_II03420
- HOGENOM:   HBG731261
- OMA:   TCLLVSE
- ProtClustDB:   PRK09293
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 36156; Mature: 36025

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00124 FBPASE

Important sites: BINDING 215-215

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIA
CEEECCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
RGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGL
HCCCCCCCCCEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSV
EEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCEEEEEEEECCCEEEECEEC
GEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGP
CCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHCCCCCCC
RGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGG
CCCCCCEEEHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCC
KATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
CCCCCCCCHHHHCCCCCCCCCEEEEECHHHHHHHHHHHCC
>Mature Secondary Structure 
TLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIA
EEECCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
RGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGL
HCCCCCCCCCEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
VAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSV
EEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCHHHCCCCCEEEEEEEECCCEEEECEEC
GEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGP
CCCEEEEEECCCCCEEEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHCHHCCCCCCC
RGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGG
CCCCCCEEEHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEECCCC
KATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
CCCCCCCCHHHHCCCCCCCCCEEEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA