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The map label for this gene is fba [H]

Identifier: 163844990

GI number: 163844990

Start: 843447

End: 844511

Strand: Reverse

Name: fba [H]

Synonym: BSUIS_B0864

Alternate gene names: 163844990

Gene position: 844511-843447 (Counterclockwise)

Preceding gene: 163844991

Following gene: 163844981

Centisome position: 60.29

GC content: 59.72

Gene sequence:

>1065_bases
ATGGCGCGCATTACGCTGCGGCAATTGCTCGATCACGCCGCTGAAAAGGGTTACGGCGTTCCGGCATTCAACATCAACAA
CATGGAACAGGCACTGGCCATCATGGAAGCGGCAAATGCCGTGGATGCGCCGGTTATCCTGCAGGCTTCGCGCGGCGCGC
GTTCCTATGCCAATGACATCATGCTCCGTCACATGATGGATGCCGTGACGGAAATCTATCCGCATATTCCGGTCTGCGTG
CATCTCGACCATGGCAACGAAGCCGCCACCTGCATGAGCGCCATCCAGGCGGGCTTCACCTCCGTCATGATGGACGGGTC
GCTGAAGGCCGACGGCAAGACGCCCGCCGACTGGGACTATAACGTCTCCGTCACGCGCCAGGTCAGCGAGATGTCGCATC
TGGGCGGCATTTCGGTGGAAGGTGAGCTCGGCGTTCTGGGTTCGCTTGAAACCGGCATGGGCGATGCCGAAGACGGCCAT
GGCGCGGAAGGCAAGCTTTCGCACGACCAGCTTCTGACCGACCCGGATGAAGCTGTGAAGTTCGTGCGCGAAACCAAGGT
CGATGCGCTGGCAATCGCCATGGGCACCTCGCACGGCGCTTACAAGTTCAGCCGCAAGCCGGATGGTTCCGTGCTCGCCA
TGCATGTGATCGAGGAAATCCATCGCAAGCTGCCGAACACCCACCTTGTCATGCATGGTTCGTCGTCGGTGCCGGAAGAA
TTGCAGGAAATCATCAACAAGTATGGCGGCCAGATGAAGCCAACCTGGGGTGTGCCGGTTGAGGAAATCCAGCGCGGCAT
CAAGCATGGCGTGCGCAAGATCAACATCGATACGGATAACCGCATGGCGATGACCGGCCAGATCCGCCGCATCTTGCAGG
AAGAACCGAGCGAATTCGATCCGCGCAAGTACCTCAAGCCCGCCATGGCTGCGATGACCAAGCTGTGCAAGGAGCGTTTC
GAGCAGTTCGGCACCGCCGGTCACGCGGCTTCCATCCGCCCGATCCCGCTTTCCGAAATGGCAAAGCGTTATCGCGACGG
TTCGCTGGACCCGAAGTTCAGCTAA

Upstream 100 bases:

>100_bases
CGAGCGCAGTGCGCTGGTGTTCGGCGTGGCCGAAGAGGTGGATATCCTCGGCGAATATTTCGTGAAATAACCTGATCTCA
CATCGACTAGGAGGCTAGAA

Downstream 100 bases:

>100_bases
ATTTTGCTGAAATTACAAAGGAAAAGCGGCCAATTGGCCGCTTTTCTGTTTTTAAATACCGGCCAATCAGCACTTGTTGT
ACTTGGCATCAACTTCGTTG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase II [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MARITLRQLLDHAAEKGYGVPAFNINNMEQALAIMEAANAVDAPVILQASRGARSYANDIMLRHMMDAVTEIYPHIPVCV
HLDHGNEAATCMSAIQAGFTSVMMDGSLKADGKTPADWDYNVSVTRQVSEMSHLGGISVEGELGVLGSLETGMGDAEDGH
GAEGKLSHDQLLTDPDEAVKFVRETKVDALAIAMGTSHGAYKFSRKPDGSVLAMHVIEEIHRKLPNTHLVMHGSSSVPEE
LQEIINKYGGQMKPTWGVPVEEIQRGIKHGVRKINIDTDNRMAMTGQIRRILQEEPSEFDPRKYLKPAMAAMTKLCKERF
EQFGTAGHAASIRPIPLSEMAKRYRDGSLDPKFS

Sequences:

>Translated_354_residues
MARITLRQLLDHAAEKGYGVPAFNINNMEQALAIMEAANAVDAPVILQASRGARSYANDIMLRHMMDAVTEIYPHIPVCV
HLDHGNEAATCMSAIQAGFTSVMMDGSLKADGKTPADWDYNVSVTRQVSEMSHLGGISVEGELGVLGSLETGMGDAEDGH
GAEGKLSHDQLLTDPDEAVKFVRETKVDALAIAMGTSHGAYKFSRKPDGSVLAMHVIEEIHRKLPNTHLVMHGSSSVPEE
LQEIINKYGGQMKPTWGVPVEEIQRGIKHGVRKINIDTDNRMAMTGQIRRILQEEPSEFDPRKYLKPAMAAMTKLCKERF
EQFGTAGHAASIRPIPLSEMAKRYRDGSLDPKFS
>Mature_353_residues
ARITLRQLLDHAAEKGYGVPAFNINNMEQALAIMEAANAVDAPVILQASRGARSYANDIMLRHMMDAVTEIYPHIPVCVH
LDHGNEAATCMSAIQAGFTSVMMDGSLKADGKTPADWDYNVSVTRQVSEMSHLGGISVEGELGVLGSLETGMGDAEDGHG
AEGKLSHDQLLTDPDEAVKFVRETKVDALAIAMGTSHGAYKFSRKPDGSVLAMHVIEEIHRKLPNTHLVMHGSSSVPEEL
QEIINKYGGQMKPTWGVPVEEIQRGIKHGVRKINIDTDNRMAMTGQIRRILQEEPSEFDPRKYLKPAMAAMTKLCKERFE
QFGTAGHAASIRPIPLSEMAKRYRDGSLDPKFS

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=328, Percent_Identity=33.2317073170732, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=32.2188449848024, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788072, Length=324, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38788; Mature: 38657

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARITLRQLLDHAAEKGYGVPAFNINNMEQALAIMEAANAVDAPVILQASRGARSYANDI
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
MLRHMMDAVTEIYPHIPVCVHLDHGNEAATCMSAIQAGFTSVMMDGSLKADGKTPADWDY
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NVSVTRQVSEMSHLGGISVEGELGVLGSLETGMGDAEDGHGAEGKLSHDQLLTDPDEAVK
CHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FVRETKVDALAIAMGTSHGAYKFSRKPDGSVLAMHVIEEIHRKLPNTHLVMHGSSSVPEE
HHHHHHHHEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LQEIINKYGGQMKPTWGVPVEEIQRGIKHGVRKINIDTDNRMAMTGQIRRILQEEPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCCCC
PRKYLKPAMAAMTKLCKERFEQFGTAGHAASIRPIPLSEMAKRYRDGSLDPKFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARITLRQLLDHAAEKGYGVPAFNINNMEQALAIMEAANAVDAPVILQASRGARSYANDI
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHH
MLRHMMDAVTEIYPHIPVCVHLDHGNEAATCMSAIQAGFTSVMMDGSLKADGKTPADWDY
HHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NVSVTRQVSEMSHLGGISVEGELGVLGSLETGMGDAEDGHGAEGKLSHDQLLTDPDEAVK
CHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FVRETKVDALAIAMGTSHGAYKFSRKPDGSVLAMHVIEEIHRKLPNTHLVMHGSSSVPEE
HHHHHHHHEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LQEIINKYGGQMKPTWGVPVEEIQRGIKHGVRKINIDTDNRMAMTGQIRRILQEEPSEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHCCCCCC
PRKYLKPAMAAMTKLCKERFEQFGTAGHAASIRPIPLSEMAKRYRDGSLDPKFS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]