Click here to switch to the map view.

The map label for this gene is patA [H]

Identifier: 163844970

GI number: 163844970

Start: 823842

End: 825296

Strand: Reverse

Name: patA [H]

Synonym: BSUIS_B0844

Alternate gene names: 163844970

Gene position: 825296-823842 (Counterclockwise)

Preceding gene: 163844971

Following gene: 163844967

Centisome position: 58.91

GC content: 57.59

Gene sequence:

>1455_bases
ATGAAAAGCACGATCCATTCCGAAGGCGCCGCCGTGTCGGCAAGTGTTGCCAATCACACGCCGAAGCCGCCGCTTTTAAG
CGTCGATGACGCCAAGGCGCTCGACCTGCCGCGCATGACGGAACTTTTCACCGCGCATCTCAACCCCGGCCAGCTTCATT
TCATGAAGCTTCTGGGCTTCCACAAGGTGAAGGTGGAGCGCGCTGAAGGCATGTATTATTACGACCAGAACGGTCGCAGG
ATACTGGATTTCTTCGGCGGTTTCGGCTCGCTGGCCTTCGGCCACAATCACCCGCGCATCATCGCGGCGCGGCGCAAGTT
TCAGGAAGAACTGCGCCATGAGATCGCAATCGCCTTCATGTCGCAATATGCAGCGGCACTTGCCTATGACCTTGCCGCCT
GCTCGCCGGGTGATCTCGACATGGTATTCCTTGGGTCTTCCGGTTCTGAAGTCATGGAAGCGGCCATCAAGGTTGCTGAA
CGCGCCGCAGGGCCGAAAAAGCCCAAGATCGTCTATGCCGAGAATTCCTTCCACGGCAAGACCAAGGGGGTGCTCTCCAT
CACCGATGGCGGGCTTTACCGAGGCGAATTCAAGCTGGTGGACAATACGGTCCGTGTGCCTTTCGGCGATATCACGGCGA
TTGAGAACGCCTTTCGCAGCGACCCGGAAATCGGCACTATCGTCCTGGAAACGGTGCAGGGTGGCGGTGGCATCATTCGG
GCGGATGCCGAATTCTGGCAGAAGCTGCGCCAGCTTTGCGACCGGTATGGTGTGATCTGGGTGGCGGATGAAGTGCAGTG
CGGCTTTGGCCGTACTGGAAAGTTCTACGCCTTTGAGCATTACGGCGTTATCCCGGATGTGACGGCTCTGGCAAAGTCTC
TGGGCGGCGGCAAGGCCGCAATGGCGGCCATGATCGCCCGGCGCGATATTTATATGAAGGCCTATGGCACGCCGAAGACG
GCGATGATCCACGCCATGGCAACGTTCGGCGGTATTGGCGAGGCCTGCATTACCGCCATCGAGGCGGTCAATATTCTCTA
TGATGAACAGCTCATCGATAACTCCGCCGAGGTTGGCGATTATCTTCTGGAACGGCTGAAAGAATTGCAGGTGCGTTATC
CGGGCCTTTTGAAGGATGTGCGCGGCAAGGGCATGATGGTGGGGCTGGAATTCCACGATTTCTCGCAGGCAATGCCGATG
GTTCTGCGGCCTATGCTCGCCATGCTGGATGACAAGCTGAAAGGCTCGCTTCCGGGCTTCATCGGCAGCCATCTGCTGCG
CGATCACGGCGTTCTCGTTGCCTTTACCGAATATAACCGCAATGTCATCCGCCTTGAGCCGCCGCTCATCTGCCAACGTG
CCCATGTGGACGAGTTCATCAAGGCGCTGGACGAAGTCCTGTCACGCGGGATCGTGAAAATCGTCAAGGACTTTATCAAG
GCGCAGATCAAGTAA

Upstream 100 bases:

>100_bases
GAAGACATGCTGATCGCTGCCTATAGTGAATATCGCAAGAAGAAGGCCGGCGGCGCTGAAAACCGCCTGAGCCCGTCAAA
AGCGGCCTGAGGAAGAAACC

Downstream 100 bases:

>100_bases
ACCCGGTCGGGATTAGAGCGCATCCCGAAAAGTGTGAAACGGTTTTCGGAAAAGATGCGCGTCAAAACAAAGGATTAGAG
CGCCGATCTGATTCAATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEVMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGGGIIR
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSLPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK

Sequences:

>Translated_484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEVMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGGGIIR
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSLPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK
>Mature_484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEVMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGGGIIR
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSLPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=474, Percent_Identity=26.5822784810127, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI13994255, Length=401, Percent_Identity=28.6783042394015, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI37574042, Length=433, Percent_Identity=25.1732101616628, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=24.7113163972286, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI226442709, Length=403, Percent_Identity=24.8138957816377, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=24.4186046511628, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=28.9156626506024, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI188536080, Length=457, Percent_Identity=22.7571115973742, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI38679950, Length=457, Percent_Identity=22.7571115973742, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI38679946, Length=457, Percent_Identity=22.7571115973742, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI145693181, Length=454, Percent_Identity=32.3788546255507, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=30.8068459657702, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789016, Length=426, Percent_Identity=30.0469483568075, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=29.8076923076923, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.5238095238095, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786991, Length=269, Percent_Identity=31.2267657992565, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786349, Length=344, Percent_Identity=29.3604651162791, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=426, Percent_Identity=28.169014084507, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=27.2935779816514, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=312, Percent_Identity=29.4871794871795, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=439, Percent_Identity=24.8291571753986, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17541228, Length=443, Percent_Identity=24.6049661399549, Blast_Score=105, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6324432, Length=335, Percent_Identity=31.3432835820896, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=29.8795180722892, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324386, Length=315, Percent_Identity=25.0793650793651, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI161085790, Length=473, Percent_Identity=28.5412262156448, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=29.3991416309013, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21357415, Length=406, Percent_Identity=27.0935960591133, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356575, Length=440, Percent_Identity=25.9090909090909, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 53290; Mature: 53290

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGF
CCCCCCCCCCEEEEHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCH
HKVKVERAEGMYYYDQNGRRILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFM
HHEEEECCCCEEEECCCCCEEHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SQYAAALAYDLAACSPGDLDMVFLGSSGSEVMEAAIKVAERAAGPKKPKIVYAENSFHGK
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
TKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGGGIIR
CCCEEEEECCCEEECEEEEECCEEECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEE
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAA
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHH
MAAMIARRDIYMKAYGTPKTAMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGD
HHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPMVLRPMLAMLDDKLKGSLPGF
HHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
HHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQIK
HCCC
>Mature Secondary Structure
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGF
CCCCCCCCCCEEEEHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCH
HKVKVERAEGMYYYDQNGRRILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFM
HHEEEECCCCEEEECCCCCEEHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SQYAAALAYDLAACSPGDLDMVFLGSSGSEVMEAAIKVAERAAGPKKPKIVYAENSFHGK
HHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
TKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGGGIIR
CCCEEEEECCCEEECEEEEECCEEECCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEEE
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAA
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHH
MAAMIARRDIYMKAYGTPKTAMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGD
HHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPMVLRPMLAMLDDKLKGSLPGF
HHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
HHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQIK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA