Click here to switch to the map view.

The map label for this gene is uxaC [H]

Identifier: 163844934

GI number: 163844934

Start: 784185

End: 785585

Strand: Reverse

Name: uxaC [H]

Synonym: BSUIS_B0804

Alternate gene names: 163844934

Gene position: 785585-784185 (Counterclockwise)

Preceding gene: 163844937

Following gene: 163844933

Centisome position: 56.08

GC content: 55.6

Gene sequence:

>1401_bases
ATGGCACTCAACCCAGACCGTCTTTTTTCGGCCGAGCCGGGTACGCGCGAAATTGCGCGGCGCCTATTCGCATCCGTGGA
AAAACTGCCGATCATCTCGCCGCACGGTCATACCGAACCCATATGGTACGCACGCAATGAAGCCTTTCCAGATCCCGCGA
GCCTGTTTGTAAAGCCTGATCACTATATCACCCGAATGCTCTATTCGCAGGGGCATTCCCTCGAAAGCCTCGGCATTGCG
TCGCGCGACGGACGGCCGAGTGAGACGGATGCACGCAAGATCTGGCGGCTGTTCGCCACCAACTGGTATCTGTTTCGCGC
TACACCGTCCCGGCTTTGGTTTGAACATGCAATGGAAACCGTGTTCGGAATTACTGAACGGCTTTCTCAGGAAAATGCGG
ATCGCATTTTCGATGCAATAGCCGACCAGCTCACTCAGCCGCATATGCGGCCGCGCGCACTTTATGACCGCTTCAATATT
GAAGCCATATCCACCACCGATGCTGCCACCGACCCGTTGATCTACCACGACGAAGTGATTGCCTCTGGCTGGCACGGCCG
TATCATCCCTGCATATCGGCCCGATGCTGCGGTTGATGCCGGGCGCCCTGATTTTGCAAGTGAGGTTGAAAAGCTGGTTG
GGGTGGCGGGCACGCCTTTGACCTGGCAAGGCTACCTTGATGCACACCGCAATCGACGAGAATATTTCAAGCGGCGCGGC
GCAACTTCGTCCGACCATGGCCATCCGACTGCCCAAACGGCCGACCTTTCTGCGGGGGATGCTTCCCGGCTTTTTGATCG
GGTCATCAAAGGAAATGCCAGCACATCGGATGCGGAGATGTTCCGGGCGCAGATGCTGACAGAGATGGCACGCATGAGTA
TTGATGATGGTCTGGTGATGCAGATCCATCCCGGTTCATTTCGCAATCACAATCCAACGGTATTTGAGCGTTTCGGGCTG
GATAAGGGTGCCGATATCCCCCGACAGACTGGATTTGTCGATCAACTGAAACCTCTGCTGGATGGTTTTGGCAATGATCC
GCGCTTGACCGTCATCTTGTTCACTCTCGATGAAACAGCCTATAGTCGCGAATTGGCGCCGCTCGCCGGCGACTATCCAG
CCTTGAAGCTTGGACCCGCATGGTGGTTCTTTGACAGTCCCGAAGGTATCCTGCGCTATCGCAAACTGACGACTGAAACT
GCCGGTTTTTATAATACGGTGGGGTTCAACGACGATACGCGCGCTTATCTTTCGATACCGGCTCGCCACGACATGGCGCG
CCGGGTTGATTGTGCCTATCTGGCAGGCCTCGTGGCAGATCACCGGCTAGAGGAAGATGAGGCATATGAAGTTGCCCATG
ATCTCGCCTACCGTTTGGCCAAACAGACCTACAAGCTTTGA

Upstream 100 bases:

>100_bases
CCAAGCTCTCGTTGATGCTTCAATCAAAAGAACGGGGAATTTCCAACAGAGTCCCATAACGAGCGCGCTCGTTTGGAAGA
ATTTAAGGGGGGCACTTCAT

Downstream 100 bases:

>100_bases
GGATGATGCCCGTGCGTACTTCGGAACCGCGCCTTTCCAACCGAACCATGTCGGGCTTGCCTTCCAGCGTGAAAGTACCG
GCCTATGATCGCTCTCGAAT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPDHYITRMLYSQGHSLESLGIA
SRDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMETVFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNI
EAISTTDAATDPLIYHDEVIASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRG
ATSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVMQIHPGSFRNHNPTVFERFGL
DKGADIPRQTGFVDQLKPLLDGFGNDPRLTVILFTLDETAYSRELAPLAGDYPALKLGPAWWFFDSPEGILRYRKLTTET
AGFYNTVGFNDDTRAYLSIPARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL

Sequences:

>Translated_466_residues
MALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPDHYITRMLYSQGHSLESLGIA
SRDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMETVFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNI
EAISTTDAATDPLIYHDEVIASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRG
ATSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVMQIHPGSFRNHNPTVFERFGL
DKGADIPRQTGFVDQLKPLLDGFGNDPRLTVILFTLDETAYSRELAPLAGDYPALKLGPAWWFFDSPEGILRYRKLTTET
AGFYNTVGFNDDTRAYLSIPARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL
>Mature_465_residues
ALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPDHYITRMLYSQGHSLESLGIAS
RDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMETVFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNIE
AISTTDAATDPLIYHDEVIASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRGA
TSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVMQIHPGSFRNHNPTVFERFGLD
KGADIPRQTGFVDQLKPLLDGFGNDPRLTVILFTLDETAYSRELAPLAGDYPALKLGPAWWFFDSPEGILRYRKLTTETA
GFYNTVGFNDDTRAYLSIPARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=434, Percent_Identity=25.8064516129032, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 52715; Mature: 52584

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHEEECCH
HYITRMLYSQGHSLESLGIASRDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMET
HHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
VFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNIEAISTTDAATDPLIYHDEVI
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCEEECCHHH
ASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRG
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCC
ATSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
QIHPGSFRNHNPTVFERFGLDKGADIPRQTGFVDQLKPLLDGFGNDPRLTVILFTLDETA
EECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCHH
YSRELAPLAGDYPALKLGPAWWFFDSPEGILRYRKLTTETAGFYNTVGFNDDTRAYLSIP
HHHHCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECC
ARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALNPDRLFSAEPGTREIARRLFASVEKLPIISPHGHTEPIWYARNEAFPDPASLFVKPD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHEEECCH
HYITRMLYSQGHSLESLGIASRDGRPSETDARKIWRLFATNWYLFRATPSRLWFEHAMET
HHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
VFGITERLSQENADRIFDAIADQLTQPHMRPRALYDRFNIEAISTTDAATDPLIYHDEVI
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCCCCEEECCHHH
ASGWHGRIIPAYRPDAAVDAGRPDFASEVEKLVGVAGTPLTWQGYLDAHRNRREYFKRRG
HCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCC
ATSSDHGHPTAQTADLSAGDASRLFDRVIKGNASTSDAEMFRAQMLTEMARMSIDDGLVM
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
QIHPGSFRNHNPTVFERFGLDKGADIPRQTGFVDQLKPLLDGFGNDPRLTVILFTLDETA
EECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCHH
YSRELAPLAGDYPALKLGPAWWFFDSPEGILRYRKLTTETAGFYNTVGFNDDTRAYLSIP
HHHHCCCCCCCCCCEEECCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECC
ARHDMARRVDCAYLAGLVADHRLEEDEAYEVAHDLAYRLAKQTYKL
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA