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The map label for this gene is ykuT [H]

Identifier: 162447858

GI number: 162447858

Start: 1025558

End: 1026376

Strand: Direct

Name: ykuT [H]

Synonym: ACL_1004

Alternate gene names: 162447858

Gene position: 1025558-1026376 (Clockwise)

Preceding gene: 162447857

Following gene: 162447881

Centisome position: 68.51

GC content: 33.82

Gene sequence:

>819_bases
ATGGACATTTTAAAAACATTTTTAACTGAGTGGTTAACAGGTCTAGCATTTGACCCTGTATTAGTTAGTTTAATCGTTAC
TGTTGCTTCAATTTTTGGTTGGATACTTATTGGTTCTGTCTTTCATATGGTCATTAAATTGGTCATTTCAAGACTTAAAG
CTAAAGAAAAACGTATGGTGAGACGTCAACGTACTGTTGCAGCACTCATATTGGCCCTTATTAAGTATTTGTTCTGGTTT
GTTATGGCCATGATGGTCTTAAAAGAATTTGGCCTTGATTTAGCCCCAATCCTTGCAAGTGCCGGTATCTTAGGTTTTGC
TGTTGGCTTTGGTGCACAAGAACTTATTAAAGACATGATAGCTGGATTCTTTATTATTTTTGAAGGTGCGATGAGTGTAG
GAGATTTTGTTGAAGTTGGTAATTTTTCCGGTACCGTTCAAGAAGTAGGTATTAGACGTACCAAAATCTTAAATTGGAAG
AATGAATTGAGATTAGTGAATAATGGTGATATTAAATCACTAACCAATTTTGCAGGTAGAGATTCAGTGGGTGTTGTAGA
GTTTTTCGTATCTGCTCAGTTTGATATAAATCATTTTACAAGTGATTCATTTAATGAGCTACTAGCTAGTTATAAAAAGT
ATGACGCTATTACTGAACTTCCAAGTTATCAAGGGGTAGTGGATACACAGTTACATAATTTAAAACTAAGAGTTATTTTT
AAGACTCAAAATCAAAAGCATTACAGTATCGAAAGAGATTTAAGACGCGATATTCAAGTGTTTATTCAAAGCATTCGAGA
AGAAACTAAAGTGTTTTAG

Upstream 100 bases:

>100_bases
TGGTTAGAAACGAATTACGGTTGGGCTGCTACACCTGCATTCTAAGACTTTAAAAAAAACCTCATTTGTGATATATTAAA
TACAAGTGAGGTATTTTTTT

Downstream 100 bases:

>100_bases
AAAAAAGCCGACTAGGTAAGAATGGGAGACATTCTAGTACCTAGTCGGTTTTTATTTTTATATATGATTAATTTCTATTT
GGATTCCATTCAATAGGGTG

Product: mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MDILKTFLTEWLTGLAFDPVLVSLIVTVASIFGWILIGSVFHMVIKLVISRLKAKEKRMVRRQRTVAALILALIKYLFWF
VMAMMVLKEFGLDLAPILASAGILGFAVGFGAQELIKDMIAGFFIIFEGAMSVGDFVEVGNFSGTVQEVGIRRTKILNWK
NELRLVNNGDIKSLTNFAGRDSVGVVEFFVSAQFDINHFTSDSFNELLASYKKYDAITELPSYQGVVDTQLHNLKLRVIF
KTQNQKHYSIERDLRRDIQVFIQSIREETKVF

Sequences:

>Translated_272_residues
MDILKTFLTEWLTGLAFDPVLVSLIVTVASIFGWILIGSVFHMVIKLVISRLKAKEKRMVRRQRTVAALILALIKYLFWF
VMAMMVLKEFGLDLAPILASAGILGFAVGFGAQELIKDMIAGFFIIFEGAMSVGDFVEVGNFSGTVQEVGIRRTKILNWK
NELRLVNNGDIKSLTNFAGRDSVGVVEFFVSAQFDINHFTSDSFNELLASYKKYDAITELPSYQGVVDTQLHNLKLRVIF
KTQNQKHYSIERDLRRDIQVFIQSIREETKVF
>Mature_272_residues
MDILKTFLTEWLTGLAFDPVLVSLIVTVASIFGWILIGSVFHMVIKLVISRLKAKEKRMVRRQRTVAALILALIKYLFWF
VMAMMVLKEFGLDLAPILASAGILGFAVGFGAQELIKDMIAGFFIIFEGAMSVGDFVEVGNFSGTVQEVGIRRTKILNWK
NELRLVNNGDIKSLTNFAGRDSVGVVEFFVSAQFDINHFTSDSFNELLASYKKYDAITELPSYQGVVDTQLHNLKLRVIF
KTQNQKHYSIERDLRRDIQVFIQSIREETKVF

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=212, Percent_Identity=30.6603773584906, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786670, Length=133, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367355, Length=141, Percent_Identity=28.3687943262411, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787591, Length=124, Percent_Identity=29.8387096774194, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 30860; Mature: 30860

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILKTFLTEWLTGLAFDPVLVSLIVTVASIFGWILIGSVFHMVIKLVISRLKAKEKRMV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQRTVAALILALIKYLFWFVMAMMVLKEFGLDLAPILASAGILGFAVGFGAQELIKDMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGFFIIFEGAMSVGDFVEVGNFSGTVQEVGIRRTKILNWKNELRLVNNGDIKSLTNFAGR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCHHHHEEEECCCCHHHHHHHCCC
DSVGVVEFFVSAQFDINHFTSDSFNELLASYKKYDAITELPSYQGVVDTQLHNLKLRVIF
CCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEEEE
KTQNQKHYSIERDLRRDIQVFIQSIREETKVF
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDILKTFLTEWLTGLAFDPVLVSLIVTVASIFGWILIGSVFHMVIKLVISRLKAKEKRMV
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQRTVAALILALIKYLFWFVMAMMVLKEFGLDLAPILASAGILGFAVGFGAQELIKDMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
AGFFIIFEGAMSVGDFVEVGNFSGTVQEVGIRRTKILNWKNELRLVNNGDIKSLTNFAGR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHCHHHHEEEECCCCHHHHHHHCCC
DSVGVVEFFVSAQFDINHFTSDSFNELLASYKKYDAITELPSYQGVVDTQLHNLKLRVIF
CCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEEEE
KTQNQKHYSIERDLRRDIQVFIQSIREETKVF
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]