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The map label for this gene is metQ [H]

Identifier: 162447857

GI number: 162447857

Start: 1024699

End: 1025502

Strand: Direct

Name: metQ [H]

Synonym: ACL_1003

Alternate gene names: 162447857

Gene position: 1024699-1025502 (Clockwise)

Preceding gene: 162447856

Following gene: 162447858

Centisome position: 68.45

GC content: 31.34

Gene sequence:

>804_bases
ATGAAAAAATTATTACTTATCACAACTACCATACTTTTAGGCTTATTAACTGCTTGTACATCTTCTGATGATGTATTAAA
AATTGGCGTAAACTTTTATCCGATGCCTGAGTTACTTGATTTAATTGAAGCGGATTTATTAGAAAAAGGTATTAAAATTG
AACAAGTTCAAATGGATTACAACGTATTAAACACGCCACTAAATAACGGTGAAATTGATGGAAACATGGTACAACATCAA
TACTTTATGGAATTCTTTAATAAGGCTAATAACGCAGAACTTGTCATTGCACAACCAATTTATCATTCTTACTTTGCATT
ATATTCAGGTGTTTATGATACGTTAGAAGATATTCCAAATGGTACAACAATTTATGTACCTGAAGATGTCGTCAATCTAC
CTAGAGCTTTAATCTTACTAGATAGTTTAGGATTAATCACTTTAAAAGAAGGCATTGATGTCACAGCTACATTAGATGAT
ATTGAATCAAACCCTAAATCCCTTGTATTTGAAACAAGATCCCTTGGTACAACATCAAGTGCATACCATTCAGATGGTTC
TAAACTAGCGATTATGTATCCGACTTATGCAAGAGATACAAATAATCAATTAATGGATGATAGTCAAGTTTTAGAATATG
AAGAATTAAATGATTTAACTAAGACCTATGCGATTAGTTTTGTAACTAGAAAAGATAATTTAAATGATCCTAGAATTCAA
ACATTTATCGAGATTCTTACATCCGGTAAAGTAAGAACTTGGTTAGAAACGAATTACGGTTGGGCTGCTACACCTGCATT
CTAA

Upstream 100 bases:

>100_bases
TGGGCTTCAACCATTATTATGATTCTAATTGTACAAGTAGTTCAACTACTTGGAAATATACTTGCAAATTATTTAAACAA
AAAGAAAAGAGGTCATTAAC

Downstream 100 bases:

>100_bases
GACTTTAAAAAAAACCTCATTTGTGATATATTAAATACAAGTGAGGTATTTTTTTATGGACATTTTAAAAACATTTTTAA
CTGAGTGGTTAACAGGTCTA

Product: ABC transporter substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKKLLLITTTILLGLLTACTSSDDVLKIGVNFYPMPELLDLIEADLLEKGIKIEQVQMDYNVLNTPLNNGEIDGNMVQHQ
YFMEFFNKANNAELVIAQPIYHSYFALYSGVYDTLEDIPNGTTIYVPEDVVNLPRALILLDSLGLITLKEGIDVTATLDD
IESNPKSLVFETRSLGTTSSAYHSDGSKLAIMYPTYARDTNNQLMDDSQVLEYEELNDLTKTYAISFVTRKDNLNDPRIQ
TFIEILTSGKVRTWLETNYGWAATPAF

Sequences:

>Translated_267_residues
MKKLLLITTTILLGLLTACTSSDDVLKIGVNFYPMPELLDLIEADLLEKGIKIEQVQMDYNVLNTPLNNGEIDGNMVQHQ
YFMEFFNKANNAELVIAQPIYHSYFALYSGVYDTLEDIPNGTTIYVPEDVVNLPRALILLDSLGLITLKEGIDVTATLDD
IESNPKSLVFETRSLGTTSSAYHSDGSKLAIMYPTYARDTNNQLMDDSQVLEYEELNDLTKTYAISFVTRKDNLNDPRIQ
TFIEILTSGKVRTWLETNYGWAATPAF
>Mature_267_residues
MKKLLLITTTILLGLLTACTSSDDVLKIGVNFYPMPELLDLIEADLLEKGIKIEQVQMDYNVLNTPLNNGEIDGNMVQHQ
YFMEFFNKANNAELVIAQPIYHSYFALYSGVYDTLEDIPNGTTIYVPEDVVNLPRALILLDSLGLITLKEGIDVTATLDD
IESNPKSLVFETRSLGTTSSAYHSDGSKLAIMYPTYARDTNNQLMDDSQVLEYEELNDLTKTYAISFVTRKDNLNDPRIQ
TFIEILTSGKVRTWLETNYGWAATPAF

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1790093, Length=251, Percent_Identity=30.6772908366534, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786396, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 30017; Mature: 30017

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLITTTILLGLLTACTSSDDVLKIGVNFYPMPELLDLIEADLLEKGIKIEQVQMDY
CCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECH
NVLNTPLNNGEIDGNMVQHQYFMEFFNKANNAELVIAQPIYHSYFALYSGVYDTLEDIPN
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
GTTIYVPEDVVNLPRALILLDSLGLITLKEGIDVTATLDDIESNPKSLVFETRSLGTTSS
CCEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEEHHHHCCCCCCEEEECCCCCCCCC
AYHSDGSKLAIMYPTYARDTNNQLMDDSQVLEYEELNDLTKTYAISFVTRKDNLNDPRIQ
HHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHH
TFIEILTSGKVRTWLETNYGWAATPAF
HHHHHHHCCCEEEEEECCCCEEECCCC
>Mature Secondary Structure
MKKLLLITTTILLGLLTACTSSDDVLKIGVNFYPMPELLDLIEADLLEKGIKIEQVQMDY
CCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECH
NVLNTPLNNGEIDGNMVQHQYFMEFFNKANNAELVIAQPIYHSYFALYSGVYDTLEDIPN
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCC
GTTIYVPEDVVNLPRALILLDSLGLITLKEGIDVTATLDDIESNPKSLVFETRSLGTTSS
CCEEEECHHHHHHHHHHHHHHCCCEEEEECCCEEEEEHHHHCCCCCCEEEECCCCCCCCC
AYHSDGSKLAIMYPTYARDTNNQLMDDSQVLEYEELNDLTKTYAISFVTRKDNLNDPRIQ
HHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHH
TFIEILTSGKVRTWLETNYGWAATPAF
HHHHHHHCCCEEEEEECCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]