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The map label for this gene is recD [H]

Identifier: 162447422

GI number: 162447422

Start: 596354

End: 598603

Strand: Direct

Name: recD [H]

Synonym: ACL_0560

Alternate gene names: 162447422

Gene position: 596354-598603 (Clockwise)

Preceding gene: 162447421

Following gene: 162447425

Centisome position: 39.84

GC content: 30.84

Gene sequence:

>2250_bases
ATGGAAATTAAAGTAAGAGGATTCATCAAATCCTATGTTTTTAAAAATGAATCTAATGGCTATACGATTGCTAAACTAGA
AACCAATGATAAAGAGTTAATCTCTATTGTTGGTTATTTTCCTTTATTAAGTGAAGAATTAGAATACGAGTTTACTGGTG
AAGAGACCATACACCCTAAATTTGGGCGTCAACTGACAGTTAAAAGTTATGAAAGATTAGAAAACACTTCAGAATCAGGT
TTAGTCAGATACTTATCCAGTGATAATTTTTCTGGTATTGGACCGGTTACAGCTGAAAAAATAGTCAGTTTATTAGGCAC
AGATGCCATAGAAAAAATAATCACTGATGAAAATGTATTAAGTCCAATTTTAAATCCAATCAAGCGAAATAGACTCAAAA
AAGAATTAATTAGTCACCAAGCTGAACAACGTATTTTTGTTAAACTTTTAGATTTAGGTCTAACTACCCGTATATCTGCT
AAATTGTTTAGCAATTATGGCAGTCAAACCTTAGAAAAGTTAGAAGAAGATCCTTATCGACTGATGTATGAAATTGATGG
ATTTGGGTTTATAAAATCAAGAGATATCGCTGAAAAATTTGGTATTTCAAAAACGGATATTAGAACTTTAAAAGCTGCAT
TAGTTTATGCACTCATAACTACATCTAATAGTGAGGGTAACCTCTACTTATTTGAAGAAGAACTGATGAGTAGAGTATCT
AGAGTCATTGATGTAGATGCTGATTTTAAACCAGCGATTGATGAACTCATTAAAGAAAATAAATTAGTATTAGAAGATGA
TAAGTACTTCTTAAAACAAATCTATAGAGATGAAATTGATATTGCAAAACGCATTAAAGAGTTAAAAACATATCCACTTG
ATCATGTGGATACTGAACTATTAGAGTTGATGTTATCTCAGATCTCTATACAAAAATCTATTGATTATACAGAAAAACAA
AGACAAGCTATTATTACAGCAATGCAAAATCCACTCACTGTTATTACTGGTGGACCAGGTACTGGTAAAACGACCTTAAT
TGATGGGTTCTTAGAGTTATATGCTAAATATTTTAAAATTAACTTAAAATCTAAAGATGCAACCAATGAGATTGCACTTA
TGGCACCAACAGGACGTGCATCTAAACGTATGAGAGAATTACTTGATTTTCCTGCACGTACGATTCACTCACATTTAGGA
TTTGATTTTGATCAGTCATTTAAGTCCAATAAAGTTCAACCACTGGTTCAAAATCTTATTATCATCGATGAAGCATCGAT
GATAGATATCTACTTAATGAAAAGACTCCTAAATAGCATTATAGATGGTACTAGAGTCGTTATTGTGGGTGATGAAGATC
AACTACCAAGTGTTGGTCCGGGCTACGTTTTAGGTGATTTAATTAGTTCTAATGTTGTACCAGTGATAAGACTTAATGAA
ATACATAGACAAGCTAAGGATTCTCATATTGTAAAACTAGCATCCTCTATTAATAATCAAAATTTAAGTCAAGAAGATTT
AATTAGTCATAATGACGTGACCTTTTATAGTGGTACTGGTGAAGATATTAAAAGAGTAATCATTAATCAAATTGGTGGCG
CCATGAAAAAAGGCTATGATTTAATTAATGACATTCAAGTTTTAATACCTCAATATAAAGGTGACTTAGGTATTGATACA
ATGAACTTAGAAATACAAGCTAAGTTTAATCCAAATTATAATCAACCACCATTTATGAAGTTTGGCGATAAAACCTACTA
CATAGGTGATAAAGTCATCCAACTTCAAAATGATAAAGACAAAGAAATCATGAATGGTGATATTGGTGTAGTTAAAGCGA
TACGTAAAAACGATAAAAATCAAAAGATTTTACAAGTAGATTTTGATGGTTTATTAGTGAATTACGATCAAAATGAACTA
GATACCTTAAACCTCGCTTATGTCATTTCAATTCATAAGTCACAAGGTTCAGAATATCAAGTAGTTTTCCTACCGATTAT
TAAAAGTTATTTACATATGCTAAAAAAAGAACTTATATATACCGCGATTACACGTGCAAAATCACATCTATTAGTATTAG
GAGATTTAAGATTACTTCAATACGCATCGAATCAGTTAGTTGAAAAAAGACATACGATGCTTAAAGAACGACTTACACAT
GATGAAGTATCATTCAACTTATTTGATCAATTAAGTGAAGAAGATGATTTAGATGAAACTAAAGATTTAAGTCCATGGGA
CTTTATGTAG

Upstream 100 bases:

>100_bases
CACCGGGTCAAGTGTGTGCGATTTATGAAGATGAAGTGTGTGTTGGTTCAGGATTTATTTCAGTAGTATACAATGAAGGG
GAAAAAAGATTATATAGCTA

Downstream 100 bases:

>100_bases
ACTAAATAAAAAGCCTTAAAGATTATACAAAATGTAATCTTTAAGGCTTTTATCTTTAAAATCTAGGCATCGTTTTCTTT
TTAGAGAAGATCCAATCAAT

Product: ATP-dependent exoDNAse (exonuclease V) subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 749

Protein sequence:

>749_residues
MEIKVRGFIKSYVFKNESNGYTIAKLETNDKELISIVGYFPLLSEELEYEFTGEETIHPKFGRQLTVKSYERLENTSESG
LVRYLSSDNFSGIGPVTAEKIVSLLGTDAIEKIITDENVLSPILNPIKRNRLKKELISHQAEQRIFVKLLDLGLTTRISA
KLFSNYGSQTLEKLEEDPYRLMYEIDGFGFIKSRDIAEKFGISKTDIRTLKAALVYALITTSNSEGNLYLFEEELMSRVS
RVIDVDADFKPAIDELIKENKLVLEDDKYFLKQIYRDEIDIAKRIKELKTYPLDHVDTELLELMLSQISIQKSIDYTEKQ
RQAIITAMQNPLTVITGGPGTGKTTLIDGFLELYAKYFKINLKSKDATNEIALMAPTGRASKRMRELLDFPARTIHSHLG
FDFDQSFKSNKVQPLVQNLIIIDEASMIDIYLMKRLLNSIIDGTRVVIVGDEDQLPSVGPGYVLGDLISSNVVPVIRLNE
IHRQAKDSHIVKLASSINNQNLSQEDLISHNDVTFYSGTGEDIKRVIINQIGGAMKKGYDLINDIQVLIPQYKGDLGIDT
MNLEIQAKFNPNYNQPPFMKFGDKTYYIGDKVIQLQNDKDKEIMNGDIGVVKAIRKNDKNQKILQVDFDGLLVNYDQNEL
DTLNLAYVISIHKSQGSEYQVVFLPIIKSYLHMLKKELIYTAITRAKSHLLVLGDLRLLQYASNQLVEKRHTMLKERLTH
DEVSFNLFDQLSEEDDLDETKDLSPWDFM

Sequences:

>Translated_749_residues
MEIKVRGFIKSYVFKNESNGYTIAKLETNDKELISIVGYFPLLSEELEYEFTGEETIHPKFGRQLTVKSYERLENTSESG
LVRYLSSDNFSGIGPVTAEKIVSLLGTDAIEKIITDENVLSPILNPIKRNRLKKELISHQAEQRIFVKLLDLGLTTRISA
KLFSNYGSQTLEKLEEDPYRLMYEIDGFGFIKSRDIAEKFGISKTDIRTLKAALVYALITTSNSEGNLYLFEEELMSRVS
RVIDVDADFKPAIDELIKENKLVLEDDKYFLKQIYRDEIDIAKRIKELKTYPLDHVDTELLELMLSQISIQKSIDYTEKQ
RQAIITAMQNPLTVITGGPGTGKTTLIDGFLELYAKYFKINLKSKDATNEIALMAPTGRASKRMRELLDFPARTIHSHLG
FDFDQSFKSNKVQPLVQNLIIIDEASMIDIYLMKRLLNSIIDGTRVVIVGDEDQLPSVGPGYVLGDLISSNVVPVIRLNE
IHRQAKDSHIVKLASSINNQNLSQEDLISHNDVTFYSGTGEDIKRVIINQIGGAMKKGYDLINDIQVLIPQYKGDLGIDT
MNLEIQAKFNPNYNQPPFMKFGDKTYYIGDKVIQLQNDKDKEIMNGDIGVVKAIRKNDKNQKILQVDFDGLLVNYDQNEL
DTLNLAYVISIHKSQGSEYQVVFLPIIKSYLHMLKKELIYTAITRAKSHLLVLGDLRLLQYASNQLVEKRHTMLKERLTH
DEVSFNLFDQLSEEDDLDETKDLSPWDFM
>Mature_749_residues
MEIKVRGFIKSYVFKNESNGYTIAKLETNDKELISIVGYFPLLSEELEYEFTGEETIHPKFGRQLTVKSYERLENTSESG
LVRYLSSDNFSGIGPVTAEKIVSLLGTDAIEKIITDENVLSPILNPIKRNRLKKELISHQAEQRIFVKLLDLGLTTRISA
KLFSNYGSQTLEKLEEDPYRLMYEIDGFGFIKSRDIAEKFGISKTDIRTLKAALVYALITTSNSEGNLYLFEEELMSRVS
RVIDVDADFKPAIDELIKENKLVLEDDKYFLKQIYRDEIDIAKRIKELKTYPLDHVDTELLELMLSQISIQKSIDYTEKQ
RQAIITAMQNPLTVITGGPGTGKTTLIDGFLELYAKYFKINLKSKDATNEIALMAPTGRASKRMRELLDFPARTIHSHLG
FDFDQSFKSNKVQPLVQNLIIIDEASMIDIYLMKRLLNSIIDGTRVVIVGDEDQLPSVGPGYVLGDLISSNVVPVIRLNE
IHRQAKDSHIVKLASSINNQNLSQEDLISHNDVTFYSGTGEDIKRVIINQIGGAMKKGYDLINDIQVLIPQYKGDLGIDT
MNLEIQAKFNPNYNQPPFMKFGDKTYYIGDKVIQLQNDKDKEIMNGDIGVVKAIRKNDKNQKILQVDFDGLLVNYDQNEL
DTLNLAYVISIHKSQGSEYQVVFLPIIKSYLHMLKKELIYTAITRAKSHLLVLGDLRLLQYASNQLVEKRHTMLKERLTH
DEVSFNLFDQLSEEDDLDETKDLSPWDFM

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=565, Percent_Identity=26.3716814159292, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 85430; Mature: 85430

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKVRGFIKSYVFKNESNGYTIAKLETNDKELISIVGYFPLLSEELEYEFTGEETIHPK
CEEEHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
FGRQLTVKSYERLENTSESGLVRYLSSDNFSGIGPVTAEKIVSLLGTDAIEKIITDENVL
CCCEEEHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
SPILNPIKRNRLKKELISHQAEQRIFVKLLDLGLTTRISAKLFSNYGSQTLEKLEEDPYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEE
LMYEIDGFGFIKSRDIAEKFGISKTDIRTLKAALVYALITTSNSEGNLYLFEEELMSRVS
EEEEECCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHHHHH
RVIDVDADFKPAIDELIKENKLVLEDDKYFLKQIYRDEIDIAKRIKELKTYPLDHVDTEL
HHEECCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LELMLSQISIQKSIDYTEKQRQAIITAMQNPLTVITGGPGTGKTTLIDGFLELYAKYFKI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
NLKSKDATNEIALMAPTGRASKRMRELLDFPARTIHSHLGFDFDQSFKSNKVQPLVQNLI
ECCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCHHHHHHCEE
IIDEASMIDIYLMKRLLNSIIDGTRVVIVGDEDQLPSVGPGYVLGDLISSNVVPVIRLNE
EECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEHHH
IHRQAKDSHIVKLASSINNQNLSQEDLISHNDVTFYSGTGEDIKRVIINQIGGAMKKGYD
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHH
LINDIQVLIPQYKGDLGIDTMNLEIQAKFNPNYNQPPFMKFGDKTYYIGDKVIQLQNDKD
HHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCEECCEEEEECCEEEEECCCCC
KEIMNGDIGVVKAIRKNDKNQKILQVDFDGLLVNYDQNELDTLNLAYVISIHKSQGSEYQ
CHHHCCCHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEEEEEECCCCCCEE
VVFLPIIKSYLHMLKKELIYTAITRAKSHLLVLGDLRLLQYASNQLVEKRHTMLKERLTH
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
DEVSFNLFDQLSEEDDLDETKDLSPWDFM
CCCHHHHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MEIKVRGFIKSYVFKNESNGYTIAKLETNDKELISIVGYFPLLSEELEYEFTGEETIHPK
CEEEHHHHHHHHHEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCC
FGRQLTVKSYERLENTSESGLVRYLSSDNFSGIGPVTAEKIVSLLGTDAIEKIITDENVL
CCCEEEHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
SPILNPIKRNRLKKELISHQAEQRIFVKLLDLGLTTRISAKLFSNYGSQTLEKLEEDPYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHCCCEE
LMYEIDGFGFIKSRDIAEKFGISKTDIRTLKAALVYALITTSNSEGNLYLFEEELMSRVS
EEEEECCCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEHHHHHHHHH
RVIDVDADFKPAIDELIKENKLVLEDDKYFLKQIYRDEIDIAKRIKELKTYPLDHVDTEL
HHEECCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LELMLSQISIQKSIDYTEKQRQAIITAMQNPLTVITGGPGTGKTTLIDGFLELYAKYFKI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHEE
NLKSKDATNEIALMAPTGRASKRMRELLDFPARTIHSHLGFDFDQSFKSNKVQPLVQNLI
ECCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHCCCHHHHHCCCCHHHHHHCEE
IIDEASMIDIYLMKRLLNSIIDGTRVVIVGDEDQLPSVGPGYVLGDLISSNVVPVIRLNE
EECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEHHH
IHRQAKDSHIVKLASSINNQNLSQEDLISHNDVTFYSGTGEDIKRVIINQIGGAMKKGYD
HHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHH
LINDIQVLIPQYKGDLGIDTMNLEIQAKFNPNYNQPPFMKFGDKTYYIGDKVIQLQNDKD
HHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCEECCEEEEECCEEEEECCCCC
KEIMNGDIGVVKAIRKNDKNQKILQVDFDGLLVNYDQNELDTLNLAYVISIHKSQGSEYQ
CHHHCCCHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCEEEEEEEEEEECCCCCCEE
VVFLPIIKSYLHMLKKELIYTAITRAKSHLLVLGDLRLLQYASNQLVEKRHTMLKERLTH
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
DEVSFNLFDQLSEEDDLDETKDLSPWDFM
CCCHHHHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]