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The map label for this gene is tlyA [H]

Identifier: 162447341

GI number: 162447341

Start: 501183

End: 501881

Strand: Direct

Name: tlyA [H]

Synonym: ACL_0478

Alternate gene names: 162447341

Gene position: 501183-501881 (Clockwise)

Preceding gene: 162447340

Following gene: 162447342

Centisome position: 33.48

GC content: 32.62

Gene sequence:

>699_bases
TTGAGATTAGATAAATATTTAACAGACCACTATAAAGACATTACACGTTCACAGTTTAGTGACTTTATTAAGCGTGGTTT
TGTAACAATTGACGATAAAGTAATAACTAAACCATCTTTTGATGTACTTGAACACCACGTTGTGAAATTTAATAAAGACG
ACGTCTTTGTTTCACGTGGTGGTGAGAAGTTAGAACATGCAATTGATGTTTTTGGTATAGATATTTCTAATAAAGTCGTC
ATCGATGTCGGTGCATCGACTGGTGGGTTTACTCAAAGTGTATTAAACCATGGGGCAAAACATGTCTATGCATATGATGT
AGGTACAGATCAGTTAGCAAAAAGCTTACGTAGTGATGTACGTGTCTCATCGTTTGAACAAACCAACATATTAGATGTTA
ATCTACCCGAAAATGATCTGATTGTTATAGATGTATCCTTTACATCGGTATTACCAATTTTAAGTCATGTCACACCTTTT
GCAAAAGAGATCATCTTTTTACTTAAACCTCAATTTGAGACAACAAAGGATATGCTTAAAAAAGGTATATTAAAATCAGA
AAAAGAAATATCTAAAATCATTGAAAAAACAACGCAACACTTAAAGTCATTATCATTACAAATCTTAGGTTTTACACCAA
GTCCAATAACCGGCAAAGATGGAAACCAAGAGTATTTAATTTACTGTACAAGGAGTTAA

Upstream 100 bases:

>100_bases
TAGAACAATCTATTGAAAAATATCAAGAAGGATTGAAATTATCAAAATCATTATATGAAATGATTAAAGCGGCTGAAGCT
TTAATTGTTGAAGTTAAATC

Downstream 100 bases:

>100_bases
TACATGCTAAATTATCTAGAAGTTAAAAATTTCGCTTTAATTGATGATTTAAATATCGAGTTTAAGCATGGTTTAACATC
ATTAACTGGAGAAACTGGTA

Product: rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRLDKYLTDHYKDITRSQFSDFIKRGFVTIDDKVITKPSFDVLEHHVVKFNKDDVFVSRGGEKLEHAIDVFGIDISNKVV
IDVGASTGGFTQSVLNHGAKHVYAYDVGTDQLAKSLRSDVRVSSFEQTNILDVNLPENDLIVIDVSFTSVLPILSHVTPF
AKEIIFLLKPQFETTKDMLKKGILKSEKEISKIIEKTTQHLKSLSLQILGFTPSPITGKDGNQEYLIYCTRS

Sequences:

>Translated_232_residues
MRLDKYLTDHYKDITRSQFSDFIKRGFVTIDDKVITKPSFDVLEHHVVKFNKDDVFVSRGGEKLEHAIDVFGIDISNKVV
IDVGASTGGFTQSVLNHGAKHVYAYDVGTDQLAKSLRSDVRVSSFEQTNILDVNLPENDLIVIDVSFTSVLPILSHVTPF
AKEIIFLLKPQFETTKDMLKKGILKSEKEISKIIEKTTQHLKSLSLQILGFTPSPITGKDGNQEYLIYCTRS
>Mature_232_residues
MRLDKYLTDHYKDITRSQFSDFIKRGFVTIDDKVITKPSFDVLEHHVVKFNKDDVFVSRGGEKLEHAIDVFGIDISNKVV
IDVGASTGGFTQSVLNHGAKHVYAYDVGTDQLAKSLRSDVRVSSFEQTNILDVNLPENDLIVIDVSFTSVLPILSHVTPF
AKEIIFLLKPQFETTKDMLKKGILKSEKEISKIIEKTTQHLKSLSLQILGFTPSPITGKDGNQEYLIYCTRS

Specific function: Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined [H]

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 26122; Mature: 26122

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDKYLTDHYKDITRSQFSDFIKRGFVTIDDKVITKPSFDVLEHHVVKFNKDDVFVSRG
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEECCCCHHHHHHHHHEECCCCEEEECC
GEKLEHAIDVFGIDISNKVVIDVGASTGGFTQSVLNHGAKHVYAYDVGTDQLAKSLRSDV
CHHHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
RVSSFEQTNILDVNLPENDLIVIDVSFTSVLPILSHVTPFAKEIIFLLKPQFETTKDMLK
CCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
KGILKSEKEISKIIEKTTQHLKSLSLQILGFTPSPITGKDGNQEYLIYCTRS
HHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRLDKYLTDHYKDITRSQFSDFIKRGFVTIDDKVITKPSFDVLEHHVVKFNKDDVFVSRG
CCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCEEECCCCHHHHHHHHHEECCCCEEEECC
GEKLEHAIDVFGIDISNKVVIDVGASTGGFTQSVLNHGAKHVYAYDVGTDQLAKSLRSDV
CHHHHHHHHHEEECCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHCC
RVSSFEQTNILDVNLPENDLIVIDVSFTSVLPILSHVTPFAKEIIFLLKPQFETTKDMLK
CCCCCCCCCEEEEECCCCCEEEEEECHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHH
KGILKSEKEISKIIEKTTQHLKSLSLQILGFTPSPITGKDGNQEYLIYCTRS
HHHCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730486 [H]