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The map label for this gene is aroA [H]

Identifier: 162447088

GI number: 162447088

Start: 210205

End: 211461

Strand: Direct

Name: aroA [H]

Synonym: ACL_0218

Alternate gene names: 162447088

Gene position: 210205-211461 (Clockwise)

Preceding gene: 162447087

Following gene: 162447089

Centisome position: 14.04

GC content: 34.61

Gene sequence:

>1257_bases
GTGTTGAAATATAAAGTGCTAGAAATTATTCCAACCAATTTATCAGGTGAAGTAAAGATTGTTTCATCTAAATCTTTATC
ACACCGATATGTACTTGCAGCAGCTCTTGCACATGGACAATCAAAGATTGATAACATATTAGACTCTGATGATTTAATAG
CCACACAAAGCGCTTTAAAAAGTTTAGGTGCAACCATTAATCAAGGATTAATTACAGGTGGTAAGGTTCAAAGAGTACAT
GAAACTATTGATTGTTTTGAGTCTGGTTCTACATTAAGATTTTTAATTCCGGTCGCAATGCTTCAAGATAAACCTGTGAC
ATTCACGGGTAAAAATCAACTACCATTTCGTACTCAAGAAATGTATGAAAACCTCTTTAAAGAAACTTATCAATTTGAGC
ATCCAAAAGATAAGTGGTTACCACTTACTGTAAGTGGTCCACTTAAAGGTGGTACATATCACTTAAGAGGTGATGTAAGT
AGCCAGTTTATTACAGGCTTACTTTATGCTTTACCACTTGCACCAAATGATTCTGAAATTATTTTAACCTCGCACTTAGA
ATCTGTTGGTTATGTAGATATGACACTCGATGTATTAGATAAATTTGGTATTAAGATTATTAAAACTGTAAATGGTTATA
AGATACCTGGAAACCAACACTATAATCCGGGCAACTACAGTGTAGAAGGTGATTTTAGTGGGGCAGCATTTTTTGTTGCA
GCAGGCTTACTTGCTGGACCAATTCACTTAACTAATTTAAATCACCATAGTTTACAAGGTGATAAAGAAATTATTGATCT
TGCAGTGAAGATGGGTGGAGATATTACACCCACAAGTGAAGGTTATTTGGTTAAACCATCTAAATTAAAAGGTATTTCTA
TTGATGTCGGACAAATTCCAGATTTAGGTCCGATACTTATGGTACTTGGTGCACTTGCAGAAGGTACTACAATTATTCAT
AACGCATCTAGATTACGTATTAAAGAATCTGATAGATTAAATGCTATGGTAACAAACCTTAAAGCACTTGGTGCAAACAT
TAAAGAAATAGGGGATACTGTAGAAATTAAAGGTGTTTCTAAACTAAAAGGCGGCGTTCTAGTTTCAAGTTATAAAGATC
ATAGAATTGCCATGTCGATGGCGGTTGCCTCCATCATGTGCGAACAACCAATTACACTAGATGATGAGACTGTAGTGTCT
AAAAGTTATCCAAATTTCTTTGAAAGTTTTAAAGCGTTAGGAGGTCAAGTAAAGTGA

Upstream 100 bases:

>100_bases
AAACAATTTATAGAATATATAGGTTTTGACAAGAAAAACCTAGCGGATGGTTTACGTTTTGTTTATATCAAAAACATAGG
TGAACCAATCATTAAGAAAG

Downstream 100 bases:

>100_bases
GTTTAGAACCCTTAAGAAATGAAATTGATAAAGTGGATAAAGAACTTGTCAAATTATTAGAGCGCCGTTTTGAATTAGTA
AAAGAAATTGGCGACTATAA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLKYKVLEIIPTNLSGEVKIVSSKSLSHRYVLAAALAHGQSKIDNILDSDDLIATQSALKSLGATINQGLITGGKVQRVH
ETIDCFESGSTLRFLIPVAMLQDKPVTFTGKNQLPFRTQEMYENLFKETYQFEHPKDKWLPLTVSGPLKGGTYHLRGDVS
SQFITGLLYALPLAPNDSEIILTSHLESVGYVDMTLDVLDKFGIKIIKTVNGYKIPGNQHYNPGNYSVEGDFSGAAFFVA
AGLLAGPIHLTNLNHHSLQGDKEIIDLAVKMGGDITPTSEGYLVKPSKLKGISIDVGQIPDLGPILMVLGALAEGTTIIH
NASRLRIKESDRLNAMVTNLKALGANIKEIGDTVEIKGVSKLKGGVLVSSYKDHRIAMSMAVASIMCEQPITLDDETVVS
KSYPNFFESFKALGGQVK

Sequences:

>Translated_418_residues
MLKYKVLEIIPTNLSGEVKIVSSKSLSHRYVLAAALAHGQSKIDNILDSDDLIATQSALKSLGATINQGLITGGKVQRVH
ETIDCFESGSTLRFLIPVAMLQDKPVTFTGKNQLPFRTQEMYENLFKETYQFEHPKDKWLPLTVSGPLKGGTYHLRGDVS
SQFITGLLYALPLAPNDSEIILTSHLESVGYVDMTLDVLDKFGIKIIKTVNGYKIPGNQHYNPGNYSVEGDFSGAAFFVA
AGLLAGPIHLTNLNHHSLQGDKEIIDLAVKMGGDITPTSEGYLVKPSKLKGISIDVGQIPDLGPILMVLGALAEGTTIIH
NASRLRIKESDRLNAMVTNLKALGANIKEIGDTVEIKGVSKLKGGVLVSSYKDHRIAMSMAVASIMCEQPITLDDETVVS
KSYPNFFESFKALGGQVK
>Mature_418_residues
MLKYKVLEIIPTNLSGEVKIVSSKSLSHRYVLAAALAHGQSKIDNILDSDDLIATQSALKSLGATINQGLITGGKVQRVH
ETIDCFESGSTLRFLIPVAMLQDKPVTFTGKNQLPFRTQEMYENLFKETYQFEHPKDKWLPLTVSGPLKGGTYHLRGDVS
SQFITGLLYALPLAPNDSEIILTSHLESVGYVDMTLDVLDKFGIKIIKTVNGYKIPGNQHYNPGNYSVEGDFSGAAFFVA
AGLLAGPIHLTNLNHHSLQGDKEIIDLAVKMGGDITPTSEGYLVKPSKLKGISIDVGQIPDLGPILMVLGALAEGTTIIH
NASRLRIKESDRLNAMVTNLKALGANIKEIGDTVEIKGVSKLKGGVLVSSYKDHRIAMSMAVASIMCEQPITLDDETVVS
KSYPNFFESFKALGGQVK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=414, Percent_Identity=31.8840579710145, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6320332, Length=457, Percent_Identity=27.5711159737418, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45340; Mature: 45340

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYKVLEIIPTNLSGEVKIVSSKSLSHRYVLAAALAHGQSKIDNILDSDDLIATQSALK
CCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHH
SLGATINQGLITGGKVQRVHETIDCFESGSTLRFLIPVAMLQDKPVTFTGKNQLPFRTQE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCEEEECCCCCCCHHHH
MYENLFKETYQFEHPKDKWLPLTVSGPLKGGTYHLRGDVSSQFITGLLYALPLAPNDSEI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
ILTSHLESVGYVDMTLDVLDKFGIKIIKTVNGYKIPGNQHYNPGNYSVEGDFSGAAFFVA
EEEECCCCCCCHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCCEEEECCCCCHHHHHH
AGLLAGPIHLTNLNHHSLQGDKEIIDLAVKMGGDITPTSEGYLVKPSKLKGISIDVGQIP
HHHHHCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCCCC
DLGPILMVLGALAEGTTIIHNASRLRIKESDRLNAMVTNLKALGANIKEIGDTVEIKGVS
CCCHHHHHHHHHHCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCHHHCCCEEEEEEHH
KLKGGVLVSSYKDHRIAMSMAVASIMCEQPITLDDETVVSKSYPNFFESFKALGGQVK
HHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKYKVLEIIPTNLSGEVKIVSSKSLSHRYVLAAALAHGQSKIDNILDSDDLIATQSALK
CCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHH
SLGATINQGLITGGKVQRVHETIDCFESGSTLRFLIPVAMLQDKPVTFTGKNQLPFRTQE
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCEEEECCCCCCCHHHH
MYENLFKETYQFEHPKDKWLPLTVSGPLKGGTYHLRGDVSSQFITGLLYALPLAPNDSEI
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCE
ILTSHLESVGYVDMTLDVLDKFGIKIIKTVNGYKIPGNQHYNPGNYSVEGDFSGAAFFVA
EEEECCCCCCCHHHHHHHHHHCCEEEEEECCCEECCCCCCCCCCCEEEECCCCCHHHHHH
AGLLAGPIHLTNLNHHSLQGDKEIIDLAVKMGGDITPTSEGYLVKPSKLKGISIDVGQIP
HHHHHCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEECCCCC
DLGPILMVLGALAEGTTIIHNASRLRIKESDRLNAMVTNLKALGANIKEIGDTVEIKGVS
CCCHHHHHHHHHHCCCEEEECCCEEEEECCCHHHHHHHHHHHHCCCHHHCCCEEEEEEHH
KLKGGVLVSSYKDHRIAMSMAVASIMCEQPITLDDETVVSKSYPNFFESFKALGGQVK
HHCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA