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The map label for this gene is arsB [H]

Identifier: 162447011

GI number: 162447011

Start: 124356

End: 125672

Strand: Direct

Name: arsB [H]

Synonym: ACL_0141

Alternate gene names: 162447011

Gene position: 124356-125672 (Clockwise)

Preceding gene: 162447010

Following gene: 162447012

Centisome position: 8.31

GC content: 30.07

Gene sequence:

>1317_bases
ATGGCACTTACACTTATTATATTTTCACTTACAGTAGTTATACTTATCTTGATGGTTATGTTTAAACCAAAACTTTATTT
TGGTAATTTTTCTATAGAATCATTTTGGCTTGTTGCAGTTATTGGTGCACTTTTATTAGTGATATTTCAACTGGTATCTC
CAAGTGAGATCTATCAAAGTTTAACAAAAAGTACTGGGATGAATCCAATTAAACTACTTATCATTTTTATTTCAATGAGT
GGTTTATCTGTGATGCTTGATGAATTGGGATTTTTTAAGAAAGTATCTATTCTGGTTTTAAAAGCTGCGGGTACAAGTCA
ACTAAAGATTTTTATCTATTTATATATGACGGTATCCTTTTTAACGATATTTACTTCTAATGACATCATTATTTTAACCT
TTACACCGATTATCATCTATTTTTCTAAACACGCTAAAATCAACCCAATACCGTATCTATTATCAGAGTTTGTAGCAGCC
AATACATGGAGCTTAATGTTTATGATTGGTAATCCAACCAATATCTATTTAGCTTCAGCATTTAATATTACGTTCTTTGA
ATACTTTAAAGTTATGATGATTCCAACGATTGCTGCAGGTACATTTACATTTATTATCTTATGGGTGTTATTCAATAAAG
ATTTAAGAAAACCAATGGATAAAACCATACTAGATAATGTAGTACTAGATAGACCGGTACTTGTATGGGTTACTTTAATT
AACCTAGTACTCGCAACCACGTTTCTTACCCTATCATCTTATATAGCTATAGAGATGTATTTGATTGCATTATGCTTCTT
ACTATTTAATGCATCCTTCATGGTCTTTTATCAAGTGTTTGTTTATAAAGAACATCCGGCATACTTTTTAAATACTGTTA
AAAGAATGCCGTGGAATTTAATGCCTTTTGTTATCTCTATGTTTATTATGGTCATTAGTCTTAATAAATATGGGGTTACA
GAAAATATAGAAGCTATGTTATCTAATTTAGATAGTTTATATGGATATGGCTTAACGTCCTTTATATCAGCAAACTTTTT
AAATAATATACCAATGTCCGTGTTATATGCAGACATTATCCATCATATGCCTTTATTACCACAACAAGCACTTAACCGTG
CGATATATAGCTCAATTATTGGATCTAATATTGGAGCTTATCTAACACCCATTGGAGCACTAGCTGGTATGATGTGGATG
CGTATCTTAAAGAAAGAAGACATAGATTTATCCTTTGGTAAATTTATTTCATATGGTGCATTATTATCTATTCCAACCAT
GTTGATTGCATTAGTTGTATTACAGTTATTTATATAA

Upstream 100 bases:

>100_bases
CTAAACATAATTTAGTCAGATATCAATTCAATAAATATATAGTATAATTAAGGCTGGCAAATATCATTTGCCAGCTTTTA
TTGTTAAAAAAGGACACTTT

Downstream 100 bases:

>100_bases
AATAAATCTAAGGTTATATAGAGATTACTATATGACCTTTATTTATTATAAGAACTTTAAATCAAGGAAATTCTAACAAT
CTATAGTGATGAATCATGTA

Product: anion permease

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MALTLIIFSLTVVILILMVMFKPKLYFGNFSIESFWLVAVIGALLLVIFQLVSPSEIYQSLTKSTGMNPIKLLIIFISMS
GLSVMLDELGFFKKVSILVLKAAGTSQLKIFIYLYMTVSFLTIFTSNDIIILTFTPIIIYFSKHAKINPIPYLLSEFVAA
NTWSLMFMIGNPTNIYLASAFNITFFEYFKVMMIPTIAAGTFTFIILWVLFNKDLRKPMDKTILDNVVLDRPVLVWVTLI
NLVLATTFLTLSSYIAIEMYLIALCFLLFNASFMVFYQVFVYKEHPAYFLNTVKRMPWNLMPFVISMFIMVISLNKYGVT
ENIEAMLSNLDSLYGYGLTSFISANFLNNIPMSVLYADIIHHMPLLPQQALNRAIYSSIIGSNIGAYLTPIGALAGMMWM
RILKKEDIDLSFGKFISYGALLSIPTMLIALVVLQLFI

Sequences:

>Translated_438_residues
MALTLIIFSLTVVILILMVMFKPKLYFGNFSIESFWLVAVIGALLLVIFQLVSPSEIYQSLTKSTGMNPIKLLIIFISMS
GLSVMLDELGFFKKVSILVLKAAGTSQLKIFIYLYMTVSFLTIFTSNDIIILTFTPIIIYFSKHAKINPIPYLLSEFVAA
NTWSLMFMIGNPTNIYLASAFNITFFEYFKVMMIPTIAAGTFTFIILWVLFNKDLRKPMDKTILDNVVLDRPVLVWVTLI
NLVLATTFLTLSSYIAIEMYLIALCFLLFNASFMVFYQVFVYKEHPAYFLNTVKRMPWNLMPFVISMFIMVISLNKYGVT
ENIEAMLSNLDSLYGYGLTSFISANFLNNIPMSVLYADIIHHMPLLPQQALNRAIYSSIIGSNIGAYLTPIGALAGMMWM
RILKKEDIDLSFGKFISYGALLSIPTMLIALVVLQLFI
>Mature_437_residues
ALTLIIFSLTVVILILMVMFKPKLYFGNFSIESFWLVAVIGALLLVIFQLVSPSEIYQSLTKSTGMNPIKLLIIFISMSG
LSVMLDELGFFKKVSILVLKAAGTSQLKIFIYLYMTVSFLTIFTSNDIIILTFTPIIIYFSKHAKINPIPYLLSEFVAAN
TWSLMFMIGNPTNIYLASAFNITFFEYFKVMMIPTIAAGTFTFIILWVLFNKDLRKPMDKTILDNVVLDRPVLVWVTLIN
LVLATTFLTLSSYIAIEMYLIALCFLLFNASFMVFYQVFVYKEHPAYFLNTVKRMPWNLMPFVISMFIMVISLNKYGVTE
NIEAMLSNLDSLYGYGLTSFISANFLNNIPMSVLYADIIHHMPLLPQQALNRAIYSSIIGSNIGAYLTPIGALAGMMWMR
ILKKEDIDLSFGKFISYGALLSIPTMLIALVVLQLFI

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=455, Percent_Identity=25.4945054945055, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 49637; Mature: 49506

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLIIFSLTVVILILMVMFKPKLYFGNFSIESFWLVAVIGALLLVIFQLVSPSEIYQS
CHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTKSTGMNPIKLLIIFISMSGLSVMLDELGFFKKVSILVLKAAGTSQLKIFIYLYMTVSF
HHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
LTIFTSNDIIILTFTPIIIYFSKHAKINPIPYLLSEFVAANTWSLMFMIGNPTNIYLASA
HHHEECCCEEEEEEHHHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEE
FNITFFEYFKVMMIPTIAAGTFTFIILWVLFNKDLRKPMDKTILDNVVLDRPVLVWVTLI
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHH
NLVLATTFLTLSSYIAIEMYLIALCFLLFNASFMVFYQVFVYKEHPAYFLNTVKRMPWNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
MPFVISMFIMVISLNKYGVTENIEAMLSNLDSLYGYGLTSFISANFLNNIPMSVLYADII
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
HHMPLLPQQALNRAIYSSIIGSNIGAYLTPIGALAGMMWMRILKKEDIDLSFGKFISYGA
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLSIPTMLIALVVLQLFI
HHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ALTLIIFSLTVVILILMVMFKPKLYFGNFSIESFWLVAVIGALLLVIFQLVSPSEIYQS
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LTKSTGMNPIKLLIIFISMSGLSVMLDELGFFKKVSILVLKAAGTSQLKIFIYLYMTVSF
HHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
LTIFTSNDIIILTFTPIIIYFSKHAKINPIPYLLSEFVAANTWSLMFMIGNPTNIYLASA
HHHEECCCEEEEEEHHHHHEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCEEEEEEE
FNITFFEYFKVMMIPTIAAGTFTFIILWVLFNKDLRKPMDKTILDNVVLDRPVLVWVTLI
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHH
NLVLATTFLTLSSYIAIEMYLIALCFLLFNASFMVFYQVFVYKEHPAYFLNTVKRMPWNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
MPFVISMFIMVISLNKYGVTENIEAMLSNLDSLYGYGLTSFISANFLNNIPMSVLYADII
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHH
HHMPLLPQQALNRAIYSSIIGSNIGAYLTPIGALAGMMWMRILKKEDIDLSFGKFISYGA
HHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLSIPTMLIALVVLQLFI
HHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]