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The map label for this gene is yegE [H]

Identifier: 162447006

GI number: 162447006

Start: 118673

End: 120118

Strand: Direct

Name: yegE [H]

Synonym: ACL_0136

Alternate gene names: 162447006

Gene position: 118673-120118 (Clockwise)

Preceding gene: 162447004

Following gene: 162447007

Centisome position: 7.93

GC content: 30.5

Gene sequence:

>1446_bases
ATGATAAATACTCACAAAAGAAATATTTTGAGAAAAGACTACATTGCGCTAAATGTAGCACTTTACATAGATGCTTTTGC
AACTATGCTTTTTATCTTTAGCGTCTACTTTGATGCCCCTACATATTTTCATTTAATATTTGAATACTTGATTTTTGTAT
CTATGGGTATCTTGTTTTTGATTATTATGCGTATCCTCAGTTCAAAATCTGAAAAACGTATTATTGCAACCTTTTCAATC
GGTATTATAGGTGTAGGACTTATTATGATATTTGGTACTAAGATGGATAAAGTGCTTGCTCAATCCTTGTTACTTGTTAT
CTTATTATCTAGAATTCTGATTGTGGATTTTAGGAAGGTTTATCCATCTAAGTATATAAAATCTACCGTTTACTTGTTGT
TTATCACAGAAACTGTGCGTTTTATTACGGAAGGGTTCATCACATCAGATCTTTTATATCACACCTTCACAGATACTTGG
GTTTCTGCATTTTCATTCATTTTAAGGGCACTTTCAATGGTGTTTATTATTATCTTACATGACCAATTATCCATTAATAA
AAATCTTGCAAAAACATTAGATATTCAATCATCAGCTAAACTACTTAACCAAGTCTTTGATCAAAATCCAAACGTTGTGA
TTCTAACCAATATGAAGCGTCAAATCATATATGCAAACAAGCAAACCATTAACTTAACAGGTTATTCAGAAGAAGAACTT
ATTGGAAGTACACCTAGTCTATTAAAAAGTGGTCTAACACCAAGAAAAACATATGATGAGCTTGAAAAAGCACTAAGAGC
TGGTGAAAGCTGGGTGGGTGAGTTTATTAATAGAAAGAAAAATGGTGAAATATTTACTGAGTTATCTAAAATTATGACAC
TTAAAGGTGTCAATGGAAAACCTATGTTTCACTTAGCAATAAAAAATGATATTACAAAAGAAAAAGCATATTTACAAGAG
TTAGAATATCGTTCAAATCATGATGATCTCACAGGACTTTTAAGACGTCAAGTTTTTATCCAAAAACTTGAATCTAATAT
GGGCATAAACCATGAACATAATCATTATTTCATACTGATGGACATCGATGAGTTTAAGTTCATCAATGATAATTATGGTC
ACTTAATTGGTGATGATATTTTAATTGAATTTAGTAGCGCTTTAAAGGAAGTGTTTGATATTAGATCTTATATTTGTAGA
TTTGGTGGCGATGAGTTTGCAGTCTATTTACATGATTATGAACCTGAACAGGTCAAACTTCTAATAGAACGCTTATATCA
AATCCTTTCTAACCACCCAATCGAATCCATTTCTAACGAATACAGATTGAGGTTTAGTTATGGTTTTACTAAGATTGAAA
TACCCGTAGATTTCAGCAAAGTTTATGAAAATTCGGATAAAAATCTATATGAACATAAAGCCACTAAAAATAACTTAAGA
AGATAA

Upstream 100 bases:

>100_bases
AAAAAACTAGCGAATTTTTAAACAAGTTGGTTAGAGGGAGAATTTTTTGATTATACTGGTTATATTGTTGGTTGTTTTTG
GTTTATCCATACAGATTTTA

Downstream 100 bases:

>100_bases
GTAGAGATAACTTCATTCCAATGATTAATTAATCACATATTTAGCATGATATACTTGACAAATCAAAGGGAATATTATAT
TATATTTCACGGTACGTTTT

Product: surface-anchored signal transduction protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MINTHKRNILRKDYIALNVALYIDAFATMLFIFSVYFDAPTYFHLIFEYLIFVSMGILFLIIMRILSSKSEKRIIATFSI
GIIGVGLIMIFGTKMDKVLAQSLLLVILLSRILIVDFRKVYPSKYIKSTVYLLFITETVRFITEGFITSDLLYHTFTDTW
VSAFSFILRALSMVFIIILHDQLSINKNLAKTLDIQSSAKLLNQVFDQNPNVVILTNMKRQIIYANKQTINLTGYSEEEL
IGSTPSLLKSGLTPRKTYDELEKALRAGESWVGEFINRKKNGEIFTELSKIMTLKGVNGKPMFHLAIKNDITKEKAYLQE
LEYRSNHDDLTGLLRRQVFIQKLESNMGINHEHNHYFILMDIDEFKFINDNYGHLIGDDILIEFSSALKEVFDIRSYICR
FGGDEFAVYLHDYEPEQVKLLIERLYQILSNHPIESISNEYRLRFSYGFTKIEIPVDFSKVYENSDKNLYEHKATKNNLR
R

Sequences:

>Translated_481_residues
MINTHKRNILRKDYIALNVALYIDAFATMLFIFSVYFDAPTYFHLIFEYLIFVSMGILFLIIMRILSSKSEKRIIATFSI
GIIGVGLIMIFGTKMDKVLAQSLLLVILLSRILIVDFRKVYPSKYIKSTVYLLFITETVRFITEGFITSDLLYHTFTDTW
VSAFSFILRALSMVFIIILHDQLSINKNLAKTLDIQSSAKLLNQVFDQNPNVVILTNMKRQIIYANKQTINLTGYSEEEL
IGSTPSLLKSGLTPRKTYDELEKALRAGESWVGEFINRKKNGEIFTELSKIMTLKGVNGKPMFHLAIKNDITKEKAYLQE
LEYRSNHDDLTGLLRRQVFIQKLESNMGINHEHNHYFILMDIDEFKFINDNYGHLIGDDILIEFSSALKEVFDIRSYICR
FGGDEFAVYLHDYEPEQVKLLIERLYQILSNHPIESISNEYRLRFSYGFTKIEIPVDFSKVYENSDKNLYEHKATKNNLR
R
>Mature_481_residues
MINTHKRNILRKDYIALNVALYIDAFATMLFIFSVYFDAPTYFHLIFEYLIFVSMGILFLIIMRILSSKSEKRIIATFSI
GIIGVGLIMIFGTKMDKVLAQSLLLVILLSRILIVDFRKVYPSKYIKSTVYLLFITETVRFITEGFITSDLLYHTFTDTW
VSAFSFILRALSMVFIIILHDQLSINKNLAKTLDIQSSAKLLNQVFDQNPNVVILTNMKRQIIYANKQTINLTGYSEEEL
IGSTPSLLKSGLTPRKTYDELEKALRAGESWVGEFINRKKNGEIFTELSKIMTLKGVNGKPMFHLAIKNDITKEKAYLQE
LEYRSNHDDLTGLLRRQVFIQKLESNMGINHEHNHYFILMDIDEFKFINDNYGHLIGDDILIEFSSALKEVFDIRSYICR
FGGDEFAVYLHDYEPEQVKLLIERLYQILSNHPIESISNEYRLRFSYGFTKIEIPVDFSKVYENSDKNLYEHKATKNNLR
R

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=257, Percent_Identity=24.9027237354086, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=32.9411764705882, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787802, Length=181, Percent_Identity=28.1767955801105, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=29.9435028248588, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787541, Length=252, Percent_Identity=25.7936507936508, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081974, Length=153, Percent_Identity=30.718954248366, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=82, Percent_Identity=41.4634146341463, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=28.2208588957055, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 55978; Mature: 55978

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTHKRNILRKDYIALNVALYIDAFATMLFIFSVYFDAPTYFHLIFEYLIFVSMGILFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IIMRILSSKSEKRIIATFSIGIIGVGLIMIFGTKMDKVLAQSLLLVILLSRILIVDFRKV
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPSKYIKSTVYLLFITETVRFITEGFITSDLLYHTFTDTWVSAFSFILRALSMVFIIILH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLSINKNLAKTLDIQSSAKLLNQVFDQNPNVVILTNMKRQIIYANKQTINLTGYSEEEL
CCHHCCCHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCEEEEECCCCHHHH
IGSTPSLLKSGLTPRKTYDELEKALRAGESWVGEFINRKKNGEIFTELSKIMTLKGVNGK
CCCCHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
PMFHLAIKNDITKEKAYLQELEYRSNHDDLTGLLRRQVFIQKLESNMGINHEHNHYFILM
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
DIDEFKFINDNYGHLIGDDILIEFSSALKEVFDIRSYICRFGGDEFAVYLHDYEPEQVKL
ECHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
LIERLYQILSNHPIESISNEYRLRFSYGFTKIEIPVDFSKVYENSDKNLYEHKATKNNLR
HHHHHHHHHCCCCHHHCCCCEEEEEEECEEEEEECCCHHHHHCCCCCHHHHHHHHHHCCC
R
C
>Mature Secondary Structure
MINTHKRNILRKDYIALNVALYIDAFATMLFIFSVYFDAPTYFHLIFEYLIFVSMGILFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IIMRILSSKSEKRIIATFSIGIIGVGLIMIFGTKMDKVLAQSLLLVILLSRILIVDFRKV
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPSKYIKSTVYLLFITETVRFITEGFITSDLLYHTFTDTWVSAFSFILRALSMVFIIILH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQLSINKNLAKTLDIQSSAKLLNQVFDQNPNVVILTNMKRQIIYANKQTINLTGYSEEEL
CCHHCCCHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCEEEEECCCCHHHH
IGSTPSLLKSGLTPRKTYDELEKALRAGESWVGEFINRKKNGEIFTELSKIMTLKGVNGK
CCCCHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
PMFHLAIKNDITKEKAYLQELEYRSNHDDLTGLLRRQVFIQKLESNMGINHEHNHYFILM
CEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
DIDEFKFINDNYGHLIGDDILIEFSSALKEVFDIRSYICRFGGDEFAVYLHDYEPEQVKL
ECHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
LIERLYQILSNHPIESISNEYRLRFSYGFTKIEIPVDFSKVYENSDKNLYEHKATKNNLR
HHHHHHHHHCCCCHHHCCCCEEEEEEECEEEEEECCCHHHHHCCCCCHHHHHHHHHHCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]