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The map label for this gene is ppa [H]

Identifier: 162446929

GI number: 162446929

Start: 54835

End: 55377

Strand: Direct

Name: ppa [H]

Synonym: ACL_0043

Alternate gene names: 162446929

Gene position: 54835-55377 (Clockwise)

Preceding gene: 162446928

Following gene: 162446930

Centisome position: 3.66

GC content: 33.89

Gene sequence:

>543_bases
ATGAATATATGGCATGACATAAATCCATCCCGCATAACACCGGAGCGTTTTATTGTTTGTATTGAGATTACTAAAGGTAG
TAAAAAGAAGTACGAACTAGATAAAGAAACAGGGATGATTATTTTAGATAGAGTATTATACACATCAGCACATTATCCAG
CGAACTACGGATTTATTCCTAGAACATATGCTGGTGACAATGACCCACTTGATGTATTAGTACTATGTCAAGAAGACATT
GAGCCAATGTCTTTAGTAGAAGTGTATCCAATTGGTGTCATTAAAATGATTGATAGTGATGAAGTAGATGAGAAAATTAT
TGCAATTCCTTATGGGGATCCATCTATGACACAGTATAAAGATTTAAAGGGGTTACCACATCATTTGCTTTCTGAGATTT
CTCACTTTTTTGAAGTGTATAAATCCCTAGAAGGAAAGAAAACATACATTCTTGACATTGAGTCAAGAGATGAGGCAATT
AAAGTTGTATCTGAGGCTATGGTCTCATACGACAAAGTATTTACAAATAAGAAAGAGAAGTAA

Upstream 100 bases:

>100_bases
AAGACTCGTATATTTGATATAATAAAACACCGCAAAAGATAGAAAAATACCTAATTTAGTGATACAATGTATATGCTAAT
AGAGGAAAAAGGTGAATATT

Downstream 100 bases:

>100_bases
ACATTATGGGTAGAGCATTCGAAGTAAGAAAAGCATCAATGGCAAAAACTGCCGCAGCAAAATCAAAAGTATATTCAAGA
TATGGTAGAGAAATCTACAT

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MNIWHDINPSRITPERFIVCIEITKGSKKKYELDKETGMIILDRVLYTSAHYPANYGFIPRTYAGDNDPLDVLVLCQEDI
EPMSLVEVYPIGVIKMIDSDEVDEKIIAIPYGDPSMTQYKDLKGLPHHLLSEISHFFEVYKSLEGKKTYILDIESRDEAI
KVVSEAMVSYDKVFTNKKEK

Sequences:

>Translated_180_residues
MNIWHDINPSRITPERFIVCIEITKGSKKKYELDKETGMIILDRVLYTSAHYPANYGFIPRTYAGDNDPLDVLVLCQEDI
EPMSLVEVYPIGVIKMIDSDEVDEKIIAIPYGDPSMTQYKDLKGLPHHLLSEISHFFEVYKSLEGKKTYILDIESRDEAI
KVVSEAMVSYDKVFTNKKEK
>Mature_180_residues
MNIWHDINPSRITPERFIVCIEITKGSKKKYELDKETGMIILDRVLYTSAHYPANYGFIPRTYAGDNDPLDVLVLCQEDI
EPMSLVEVYPIGVIKMIDSDEVDEKIIAIPYGDPSMTQYKDLKGLPHHLLSEISHFFEVYKSLEGKKTYILDIESRDEAI
KVVSEAMVSYDKVFTNKKEK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=163, Percent_Identity=38.0368098159509, Blast_Score=108, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319483, Length=191, Percent_Identity=24.6073298429319, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20724; Mature: 20724

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIWHDINPSRITPERFIVCIEITKGSKKKYELDKETGMIILDRVLYTSAHYPANYGFIP
CCCCCCCCCCCCCHHHEEEEEEECCCCCCEEECCCCCCCEEEHHHHHHCCCCCCCCCCCC
RTYAGDNDPLDVLVLCQEDIEPMSLVEVYPIGVIKMIDSDEVDEKIIAIPYGDPSMTQYK
CCCCCCCCCEEEEEEECCCCCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCCHHHH
DLKGLPHHLLSEISHFFEVYKSLEGKKTYILDIESRDEAIKVVSEAMVSYDKVFTNKKEK
HHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNIWHDINPSRITPERFIVCIEITKGSKKKYELDKETGMIILDRVLYTSAHYPANYGFIP
CCCCCCCCCCCCCHHHEEEEEEECCCCCCEEECCCCCCCEEEHHHHHHCCCCCCCCCCCC
RTYAGDNDPLDVLVLCQEDIEPMSLVEVYPIGVIKMIDSDEVDEKIIAIPYGDPSMTQYK
CCCCCCCCCEEEEEEECCCCCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCCHHHH
DLKGLPHHLLSEISHFFEVYKSLEGKKTYILDIESRDEAIKVVSEAMVSYDKVFTNKKEK
HHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA