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The map label for this gene is exuR [H]

Identifier: 162446921

GI number: 162446921

Start: 40937

End: 41956

Strand: Direct

Name: exuR [H]

Synonym: ACL_0035

Alternate gene names: 162446921

Gene position: 40937-41956 (Clockwise)

Preceding gene: 162446920

Following gene: 162446922

Centisome position: 2.73

GC content: 32.16

Gene sequence:

>1020_bases
ATGGTGAAGTTAAAGGATATTGCTGATGTGGCTGGTGTAAGTATTGGTACAGTGAGTAAAGCCTTAAGCAATAGTCATGA
AATCAGTATTAAAGTCACAAAGAAAATACATAAGATTGCCAGAGAAATGGGATATATCGCAAACTCTCAAGCTAGGAGTT
TAAAAACAAATAGATCCTATAATATCGGTGTTGTATATATTGATAAATCTAAAGCAGGTTTAAAGCATGAGTATTTTTCA
ACTATGCTAAGTAGTATACAAGAAACCTTACGTATCAAAGGATATGACTTTACCTTCATCTCTAATTTGGTTGGTACAAC
AAAGCATACCTTATTAAGTCATGCACGCTACCGAAGATGTGATGGTGTCATTATTGCTACTGCAGACTATGATGATCCTG
AAATTCATCAACTTATGGCATCAGACATGAAGGTTGTTACAATTGATCATGATTTTCCAAATAGAACAGCTATCATGTCG
GATAATAATATTGGTTTAGGAAAGATTGTGGATTATATATATAAATTAGGTCACACCAAAATTGCATTTATACATGGTGA
AATGACCCAAGTTACGAAAGATAGATTAGAATCTTTTAAAACAGCATGTCAAAGACTAAATATCGATATACCACAAGCAT
ATATTAAACAAGCAGATTATCATTTACCAAAACAAAGTGGTATAGCAACCAGGGAATTACTTAGTTTAGATGAAAAACCA
ACATGTATCATATATCCTGATGATTACTCATTTATGGGCGGGATGACTGAAATAGAAAAACATGGATTAAGCATACCGAA
TGATATTTCAGTTGTTGGATATGACGGGATTTATCTATCTAGAATACTTAGACCAACGCTAACAACTTATGTTCAAAATA
GCGAAGAGATTGGTAAACAAGCAGCATTAAAGCTTATCAATCATATAGAAAATCCCAAAGAGTTTATTTCTGAAAGAATA
ACAATTACTGGAAAACTTCAAAAGGGTCATACAGTTAAAGATATTAAAAACACTTTTTAA

Upstream 100 bases:

>100_bases
ATAAAACGCTTACATTCAGGTAAAAAAATTGCTTGAATTAAAAAAGTGACATGATAAAATATAGTTGCGCAAACGTTTAC
GTCGATAGGGGATTGATAAT

Downstream 100 bases:

>100_bases
AATTTAAAATATAGAAAAGGGGTACTAAAATGTTTAAAAAGTTATTTGTAGGGTTACTTGTATTACTTGCAGCTATTGGG
TTAGTTGCTTGTGACAATGG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MVKLKDIADVAGVSIGTVSKALSNSHEISIKVTKKIHKIAREMGYIANSQARSLKTNRSYNIGVVYIDKSKAGLKHEYFS
TMLSSIQETLRIKGYDFTFISNLVGTTKHTLLSHARYRRCDGVIIATADYDDPEIHQLMASDMKVVTIDHDFPNRTAIMS
DNNIGLGKIVDYIYKLGHTKIAFIHGEMTQVTKDRLESFKTACQRLNIDIPQAYIKQADYHLPKQSGIATRELLSLDEKP
TCIIYPDDYSFMGGMTEIEKHGLSIPNDISVVGYDGIYLSRILRPTLTTYVQNSEEIGKQAALKLINHIENPKEFISERI
TITGKLQKGHTVKDIKNTF

Sequences:

>Translated_339_residues
MVKLKDIADVAGVSIGTVSKALSNSHEISIKVTKKIHKIAREMGYIANSQARSLKTNRSYNIGVVYIDKSKAGLKHEYFS
TMLSSIQETLRIKGYDFTFISNLVGTTKHTLLSHARYRRCDGVIIATADYDDPEIHQLMASDMKVVTIDHDFPNRTAIMS
DNNIGLGKIVDYIYKLGHTKIAFIHGEMTQVTKDRLESFKTACQRLNIDIPQAYIKQADYHLPKQSGIATRELLSLDEKP
TCIIYPDDYSFMGGMTEIEKHGLSIPNDISVVGYDGIYLSRILRPTLTTYVQNSEEIGKQAALKLINHIENPKEFISERI
TITGKLQKGHTVKDIKNTF
>Mature_339_residues
MVKLKDIADVAGVSIGTVSKALSNSHEISIKVTKKIHKIAREMGYIANSQARSLKTNRSYNIGVVYIDKSKAGLKHEYFS
TMLSSIQETLRIKGYDFTFISNLVGTTKHTLLSHARYRRCDGVIIATADYDDPEIHQLMASDMKVVTIDHDFPNRTAIMS
DNNIGLGKIVDYIYKLGHTKIAFIHGEMTQVTKDRLESFKTACQRLNIDIPQAYIKQADYHLPKQSGIATRELLSLDEKP
TCIIYPDDYSFMGGMTEIEKHGLSIPNDISVVGYDGIYLSRILRPTLTTYVQNSEEIGKQAALKLINHIENPKEFISERI
TITGKLQKGHTVKDIKNTF

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=318, Percent_Identity=27.9874213836478, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=27.8787878787879, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787948, Length=343, Percent_Identity=26.8221574344023, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788474, Length=299, Percent_Identity=26.4214046822742, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789202, Length=301, Percent_Identity=26.2458471760797, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=25.8675078864353, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=27.7258566978193, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789068, Length=299, Percent_Identity=23.4113712374582, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=23.1003039513678, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790715, Length=327, Percent_Identity=22.0183486238532, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=21.8518518518519, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38132; Mature: 38132

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLKDIADVAGVSIGTVSKALSNSHEISIKVTKKIHKIAREMGYIANSQARSLKTNRSY
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
NIGVVYIDKSKAGLKHEYFSTMLSSIQETLRIKGYDFTFISNLVGTTKHTLLSHARYRRC
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DGVIIATADYDDPEIHQLMASDMKVVTIDHDFPNRTAIMSDNNIGLGKIVDYIYKLGHTK
CCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCE
IAFIHGEMTQVTKDRLESFKTACQRLNIDIPQAYIKQADYHLPKQSGIATRELLSLDEKP
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
TCIIYPDDYSFMGGMTEIEKHGLSIPNDISVVGYDGIYLSRILRPTLTTYVQNSEEIGKQ
EEEEECCCCHHHCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
AALKLINHIENPKEFISERITITGKLQKGHTVKDIKNTF
HHHHHHHHCCCHHHHHHCCEEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MVKLKDIADVAGVSIGTVSKALSNSHEISIKVTKKIHKIAREMGYIANSQARSLKTNRSY
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHCCCCC
NIGVVYIDKSKAGLKHEYFSTMLSSIQETLRIKGYDFTFISNLVGTTKHTLLSHARYRRC
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
DGVIIATADYDDPEIHQLMASDMKVVTIDHDFPNRTAIMSDNNIGLGKIVDYIYKLGHTK
CCEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCEEEECCCCCCHHHHHHHHHHCCCCE
IAFIHGEMTQVTKDRLESFKTACQRLNIDIPQAYIKQADYHLPKQSGIATRELLSLDEKP
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHCCCCCC
TCIIYPDDYSFMGGMTEIEKHGLSIPNDISVVGYDGIYLSRILRPTLTTYVQNSEEIGKQ
EEEEECCCCHHHCCHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCHHHHHHH
AALKLINHIENPKEFISERITITGKLQKGHTVKDIKNTF
HHHHHHHHCCCHHHHHHCCEEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]