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The map label for this gene is degQ [H]

Identifier: 162421485

GI number: 162421485

Start: 1177828

End: 1179219

Strand: Direct

Name: degQ [H]

Synonym: YpAngola_A1137

Alternate gene names: 162421485

Gene position: 1177828-1179219 (Clockwise)

Preceding gene: 162420229

Following gene: 162419500

Centisome position: 26.15

GC content: 48.49

Gene sequence:

>1392_bases
TTGAGAGAGTTTAAATCAATGAAGAAAACATCATTACTTCTTAGTGCGCTAGCAATAAGCGTCGGCTTAGGTCTCGCTTC
TGTTCCTATGGTGAGTGCAGCAGCACTGCCTGCGGCGGTCGCCGGACAAACGTTACCTAGCCTGGCACCAATGCTGGAAA
AAGTATTACCCGCCGTTGTCAGTGTTCATGTCTCTGGGAGCCAGGCACAGCAACAACGCTTGCCAGAAGAGTTTAAATTC
TTCTTTGGCCCGAATGCACCATCAGGAAAAGAGAGCAGCCGGCCATTCGAAGGCTTAGGATCAGGCGTTATTATTAACGC
TGAGAAGGGCTACATCCTGACCAACAATCACGTCATCAATAATGCCGATAAAATTCGTGTTCAGCTGAATGATGGTCGTG
AATACGATGCAAAATTGTTGGGTCGTGATGAACAAACCGACATCGCTTTACTGCAATTAACGGATGCTAAAAATCTGACT
GCGATCAAAATTGCAGATTCCGATAACCTGCGGGTGGGGGATTTTGCTGTCGCCGTAGGTAACCCGTTTGGTCTAGGGCA
AACCGCGACGTCAGGTATTATTTCAGCACTGGGTCGTAGTGGCTTGAATCTGGAAGGGCTGGAAAACTTTATCCAGACCG
ATGCCTCAATCAACCGTGGTAATTCTGGCGGTGCTCTGGTGAATCTGGATGGGGAACTGATCGGAATTAATACCGCCATC
CTTGCGCCAGGTGGCGGTAATATCGGTATCGGCTTCGCTATCCCAAGTAACATGGCACAAAACCTCAGCCAGCAGTTGAT
CGAGTTTGGCGAAGTGAAACGTGGGCTGCTCGGTATCCGTGGTAGTGAGATGACGGCTGACATTGCGAAAGCCTTTAATA
TTGATGCTCAGCGTGGGGCTTTTGTCAGTGAAGTGCTGCCAAAATCAGCGGCAGCGAAAGCCGGGATCAAACCAGGTGAT
GTGTTGATTTCCGTTGATGGGAAAAAGATTAGCAGCTTTGCTGAATTGCGCGCCAAAGTCGGGACAACGGGGCCAGGCAA
AACCATTAAAATTGGTTTACTGCGCGAAGGGAAACCACTGGAAGTATCGGTGACGCTGGATAACAGTAGCTCAACATCCA
CCAGCGCTGAAAATCTATCGCCATCATTACAGGGCGCATCCCTGAGTAACGGTGAGCTCAAAGACGGTAGTAAGGGGATC
AAAGTTGATAGCGTCACTAAAGGTTCGCCAGCCGCACAATCTGGCTTACAAAAAGATGATGTGATTATTGCCGTAAACCG
CGAACGGGTTAAGGATATTGCTGAGTTGCGTAAAGCCATCGAAGCCAAACCTGCCGTGATTGCACTGAATATCGTGCGTG
GTGAAGATAATATTTACTTATTAATCCGCTAA

Upstream 100 bases:

>100_bases
ATACTATCCTTTTGAAATGAGCGAATTTTTTTGCTATTTACGGGTCTGAATTTATACAGACTAGTGAGCGTCATCCACCC
TATTCATTCACCGTTAGGTA

Downstream 100 bases:

>100_bases
TTTGCAGAAATAAATATCCTCCGGCATAGCCGGAGGTTTTTCATATGCGCCTATAAGGCTCTGTTACCAGCCGCGCCCTA
ACAGGCGCATCGCGATCTGA

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MREFKSMKKTSLLLSALAISVGLGLASVPMVSAAALPAAVAGQTLPSLAPMLEKVLPAVVSVHVSGSQAQQQRLPEEFKF
FFGPNAPSGKESSRPFEGLGSGVIINAEKGYILTNNHVINNADKIRVQLNDGREYDAKLLGRDEQTDIALLQLTDAKNLT
AIKIADSDNLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLDGELIGINTAI
LAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGAFVSEVLPKSAAAKAGIKPGD
VLISVDGKKISSFAELRAKVGTTGPGKTIKIGLLREGKPLEVSVTLDNSSSTSTSAENLSPSLQGASLSNGELKDGSKGI
KVDSVTKGSPAAQSGLQKDDVIIAVNRERVKDIAELRKAIEAKPAVIALNIVRGEDNIYLLIR

Sequences:

>Translated_463_residues
MREFKSMKKTSLLLSALAISVGLGLASVPMVSAAALPAAVAGQTLPSLAPMLEKVLPAVVSVHVSGSQAQQQRLPEEFKF
FFGPNAPSGKESSRPFEGLGSGVIINAEKGYILTNNHVINNADKIRVQLNDGREYDAKLLGRDEQTDIALLQLTDAKNLT
AIKIADSDNLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLDGELIGINTAI
LAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGAFVSEVLPKSAAAKAGIKPGD
VLISVDGKKISSFAELRAKVGTTGPGKTIKIGLLREGKPLEVSVTLDNSSSTSTSAENLSPSLQGASLSNGELKDGSKGI
KVDSVTKGSPAAQSGLQKDDVIIAVNRERVKDIAELRKAIEAKPAVIALNIVRGEDNIYLLIR
>Mature_463_residues
MREFKSMKKTSLLLSALAISVGLGLASVPMVSAAALPAAVAGQTLPSLAPMLEKVLPAVVSVHVSGSQAQQQRLPEEFKF
FFGPNAPSGKESSRPFEGLGSGVIINAEKGYILTNNHVINNADKIRVQLNDGREYDAKLLGRDEQTDIALLQLTDAKNLT
AIKIADSDNLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLDGELIGINTAI
LAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGAFVSEVLPKSAAAKAGIKPGD
VLISVDGKKISSFAELRAKVGTTGPGKTIKIGLLREGKPLEVSVTLDNSSSTSTSAENLSPSLQGASLSNGELKDGSKGI
KVDSVTKGSPAAQSGLQKDDVIIAVNRERVKDIAELRKAIEAKPAVIALNIVRGEDNIYLLIR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=301, Percent_Identity=37.5415282392027, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI22129776, Length=319, Percent_Identity=37.6175548589342, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24308541, Length=307, Percent_Identity=32.2475570032573, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI7019477, Length=308, Percent_Identity=34.4155844155844, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1789629, Length=458, Percent_Identity=72.0524017467249, Blast_Score=648, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=454, Percent_Identity=57.7092511013216, Blast_Score=516, Evalue=1e-148,
Organism=Escherichia coli, GI1789630, Length=278, Percent_Identity=47.1223021582734, Blast_Score=218, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=34.2560553633218, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 48179; Mature: 48179

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREFKSMKKTSLLLSALAISVGLGLASVPMVSAAALPAAVAGQTLPSLAPMLEKVLPAVV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHE
SVHVSGSQAQQQRLPEEFKFFFGPNAPSGKESSRPFEGLGSGVIINAEKGYILTNNHVIN
EEEECCCHHHHHHCCHHHHEEECCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEEC
NADKIRVQLNDGREYDAKLLGRDEQTDIALLQLTDAKNLTAIKIADSDNLRVGDFAVAVG
CCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCEEECEEEEEEC
NPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLDGELIGINTAI
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEE
LAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGA
EECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
FVSEVLPKSAAAKAGIKPGDVLISVDGKKISSFAELRAKVGTTGPGKTIKIGLLREGKPL
HHHHHCCCHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCE
EVSVTLDNSSSTSTSAENLSPSLQGASLSNGELKDGSKGIKVDSVTKGSPAAQSGLQKDD
EEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCCCCC
VIIAVNRERVKDIAELRKAIEAKPAVIALNIVRGEDNIYLLIR
EEEEECHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MREFKSMKKTSLLLSALAISVGLGLASVPMVSAAALPAAVAGQTLPSLAPMLEKVLPAVV
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHE
SVHVSGSQAQQQRLPEEFKFFFGPNAPSGKESSRPFEGLGSGVIINAEKGYILTNNHVIN
EEEECCCHHHHHHCCHHHHEEECCCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCEEEC
NADKIRVQLNDGREYDAKLLGRDEQTDIALLQLTDAKNLTAIKIADSDNLRVGDFAVAVG
CCEEEEEEECCCCCCCHHHCCCCCCCCEEEEEEECCCCEEEEEEECCCCEEECEEEEEEC
NPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGALVNLDGELIGINTAI
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEE
LAPGGGNIGIGFAIPSNMAQNLSQQLIEFGEVKRGLLGIRGSEMTADIAKAFNIDAQRGA
EECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
FVSEVLPKSAAAKAGIKPGDVLISVDGKKISSFAELRAKVGTTGPGKTIKIGLLREGKPL
HHHHHCCCHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCE
EVSVTLDNSSSTSTSAENLSPSLQGASLSNGELKDGSKGIKVDSVTKGSPAAQSGLQKDD
EEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCCCCC
VIIAVNRERVKDIAELRKAIEAKPAVIALNIVRGEDNIYLLIR
EEEEECHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]