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The map label for this gene is treB [H]

Identifier: 162420263

GI number: 162420263

Start: 1199861

End: 1201312

Strand: Direct

Name: treB [H]

Synonym: YpAngola_A1163

Alternate gene names: 162420263

Gene position: 1199861-1201312 (Clockwise)

Preceding gene: 162420317

Following gene: 162421393

Centisome position: 26.64

GC content: 51.45

Gene sequence:

>1452_bases
ATGCGCGCACGTAACCTTTACGGAAAGGACGATAAAATGGGCAAAGTAAAACAGCAGGATATCGATCAACTGATCGTTCT
GGTGGGAGGCAGAGAAAATATTGCCACCGTCAGTCACTGCATTACTCGATTACGTTTTGTATTAAAAGATCCGTCGATAG
CATCACCAAAAGAGATTGAAAATCTCTCAATGGTCAAAGGCTGTTTTACTAATGCAGGCCAATTTCAAGTGGTCATCGGG
CCAGAAGTCGATGATTACTATAAAGCATTGATTGCTAAGATTGGCCAAAGTGAAGTGGACAAAGAACAGACCAAGCTCGC
GGCACGGCAGAACATGACTTGGTTTGAGCGCGGTATTTCTCACTTTGCTGAGATCTTCTTCCCGTTGCTACCGGCGCTGA
TCAGCGGAGGGTTAATCCTCGGCTTCCGTAATGTCATCGGTGACATCCCAATGTCTGAGGGGAAAACGCTGGCGCAGATG
TACCCCGCGTGGCAAACCATTTATGACTTCCTCTGGTTACTTGGCGAAGCCATCTTCTTCTACTTGCCTGTCGCGATCTG
CTGGTCAACAGTGAAGAAAATGGGCGGGACCCCGGTATTGGGGATTGTACTGGGGATCACACTGGTCTCTCCGCAATTGA
TGAACTCCTACTTACTGGGGCAACAACTGCCTGACGTCTGGAACTTCGGTTGGTTTACCATTGAAAAAGTGGGTTATCAG
GCACAGGTGATCCCCTCTATTTTGGCGGGTCTGGCGCTGGGGTGGATTGAAACCAACTTGAAGAGAATCATCCCCGCCTA
TCTCTACCTGGTGGTCGTCCCTGTGGTCTCCCTGCTGCTAGCCGTGTTCCTGGCCCATACACTGATTGGGCCGTTTGGCC
GCATGATTGGTGACGGTGTGGCATGGGGCGTGAAGGCGGTGATGACCGGCAGTTTCGCACCGGTCGGTGCGGCACTATTT
GGTTTCCTGTATGCACCGCTGGTGATTACTGGGGTACATCAGACCACGCTGGCTATTGATATGCAGATGGTTCAGAGCAT
GGGCGGCACACCGGTCTGGCCATTGATTGCGTTGTCCAACATCGCACAAGCTTCGGCGGTACTGGGTATCATCATCATCA
GCCGTAAAATCAATGAACGTGAGATTTCAGTACCCGCAGCGATCTCCGCCTATCTGGGCGTGACCGAACCAGCAATGTAC
GGTATCAATCTGAAATACCGTTTCCCGATGTTATGCGCCATGATCGGTTCCGCACTGGCTGGCCTGATTTGTGGGTTGAC
GGGAGTCATGGCGAACGGCATCGGTGTGGGTGGGTTGCCCGGTATTTTATCTATCCAACCGCAGTTCTGGGGAATTTATG
CCGTGGCGATGTTAGTGGCCATCGTGGTGCCATTAGCACTGACCATTCTGGTGTATAAGCGTAAAGAGCGTCGTGGCGAA
TTGCCAGTCTGA

Upstream 100 bases:

>100_bases
TCAGTGTCGCCATTTGGGTGAGTGAGCGTCGCGGTAACACCGAGTAAAAAGGGAATTATAGATTTAATTCGCTGCTGACT
TCAGGCAGAGATGGCATCTC

Downstream 100 bases:

>100_bases
AGGGTGTCGATCTGGATGATGTCGATATAAGTTGTGTTCTCCCGCCAGCGGTGATCGTCTGGCGGGGTCATTTTTCAATG
AATAAGAGTCCGCTATGAAT

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRARNLYGKDDKMGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIG
PEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQM
YPAWQTIYDFLWLLGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQ
AQVIPSILAGLALGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALF
GFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMY
GINLKYRFPMLCAMIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGE
LPV

Sequences:

>Translated_483_residues
MRARNLYGKDDKMGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIG
PEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQM
YPAWQTIYDFLWLLGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQ
AQVIPSILAGLALGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALF
GFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMY
GINLKYRFPMLCAMIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGE
LPV
>Mature_483_residues
MRARNLYGKDDKMGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIG
PEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQM
YPAWQTIYDFLWLLGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQ
AQVIPSILAGLALGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALF
GFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMY
GINLKYRFPMLCAMIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGE
LPV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=471, Percent_Identity=80.4670912951168, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=408, Percent_Identity=26.9607843137255, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788769, Length=427, Percent_Identity=26.6978922716628, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI48994906, Length=425, Percent_Identity=25.1764705882353, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 52463; Mature: 52463

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARNLYGKDDKMGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIE
CCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
NLSMVKGCFTNAGQFQVVIGPEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGIS
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHH
HFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLWLLGEAIFF
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHCCCCEEHHHHCCH
AQVIPSILAGLALGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
AWGVKAVMTGSFAPVGAALFGFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCAMIGSALA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEHHHHHHHHHHHHHH
GLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGE
HHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPV
CCC
>Mature Secondary Structure
MRARNLYGKDDKMGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIE
CCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
NLSMVKGCFTNAGQFQVVIGPEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGIS
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHH
HFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLWLLGEAIFF
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHCCCCEEHHHHCCH
AQVIPSILAGLALGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
AWGVKAVMTGSFAPVGAALFGFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSN
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCAMIGSALA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEHHHHHHHHHHHHHH
GLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGE
HHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]