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The map label for this gene is yeeJ [C]

Identifier: 162419445

GI number: 162419445

Start: 2081872

End: 2083944

Strand: Direct

Name: yeeJ [C]

Synonym: YpAngola_A1994

Alternate gene names: 162419445

Gene position: 2081872-2083944 (Clockwise)

Preceding gene: 162419659

Following gene: 162419951

Centisome position: 46.22

GC content: 50.17

Gene sequence:

>2073_bases
ATGCCGGAGGATATTTATTTTGGTAAAGATAATCTGCAACGCAACCCTTATGCCGTGACTGCCGGGATCAATTACACCCC
CGTGCCTCTACTCACTGTCGGGGTAGATCAGCGTATGGGGAAAAGCAGTAAGCATGAAACACAGTGGAACCTCCAAATGA
ACTATCGCCTGGGCGAGAGTTTTCAGTCGCAACTTAGCCCTTCAGCGGTGGCGGGAACACGTCTACTGGCTGAGAGCCGC
TATAACCTTGTCGATCGTAACAATAATATCGTGTTGGAGTATCAGAAACAGCAGGTGGTTAAACTGACATTATCGCCAGC
AACTATCTCCGGCCTGCCGGGTCAGGTTTATCAGGTGAACGCACAAGTACAAGGGGCATCTGCTGTAAGGGAAATTGTCT
GGAGTGATGCCGAACTGATTGCCGCTGGCGGCACATTAACACCACTGAGTACCACACAATTCAACTTGGTTTTACCGCCT
TATAAACGCACAGCACAAGTGAGTCGGGTAACGGACGACCTGACAGCCAACTTTTATTCGCTTAGTGCGCTCGCGGTTGA
TCACCAAGGAAACAGATCTAACTCATTCACATTGAGCGTCACCGTTCAGCAGCCTCAGTTGACATTAACGGCGGCCGTCA
TTGGTGATGGCGCACCGGCTAGTGGGAAAACTGCAATCACCGTTGAGTTCACCGTTGCTGATTTTGAGGGGAAACCCTTA
GCCGGGCAGGAGGTGGTGATAACCACCAATAATGGTGCGCTACCGAATAAAATCACGGAAAAGACAGATGCAAATGGCGT
CGCGCGCATTGCATTAACCAATACGACAGATGGCGTGACGGTAGTCACAGCAGAAGTGGAGGGGCAACGGCAAAGTGTTG
ATACCCACTTTGTTAAGGGTACTATCGCGGCGGATAAATCCACTCTGGCTGCGGTACCGACATCTATCATCGCTGATGGT
CTAATGGCTTCAACCATCACGTTGGAGTTGAAGGATACCTATGGGGACCCGCAGGCTGGCGCGAATGTGGCTTTTGACAC
AACCTTAGGCAATATGGGCGTTATCACGGATCACAATGACGGCACTTATAGCGCACCATTGACCAGTACCACGTTGGGGG
TAGCAACAGTAACGGTGAAAGTGGATGGGGCTGCGTTCAGTGTGCCGAGTGTGACGGTTAATTTCACGGCAGATCCTATT
CCAGATGCTGGCCGCTCCAGTTTCACCGTCTCCACACCGGATATCTTGGCTGATGGCACGATGAGTTCCACATTATCCTT
TGTCCCTGTCGATAAGAATGGCCATTTTATCAGTGGGATGCAGGGCTTGAGTTTTACTCAAAACGGTGTGCCGGTGAGTA
TTAGCCCCATTACCGAGCAGCCAGATAGCTATACCGCGACGGTGGTTGGGAATACCGCCGGTGATGTCACAATCACGCCT
CAGGTTGATACCCTGATACTGAGTACATTGCAGAAAAAAATATCCCTATTCCCGGTACCTACGCTGACCGGTATTCTGGT
TAACGGGCAAAATTTCGCTACGGATAAAGGGTTCCCGAAAACGATCTTTAAAAACGCCACATTCCAGTTACAGATGGATA
ACGATGTTGCTAATAATACTCAGTATGAGTGGTCGTCGTCATTCACACCCAATGTATCGGTTAACGATCAGGGTCAGGTG
ACGATTACCTACCAAACCTATAGCGAAGTGGCTGTGACGGCGAAAAGTAAAAAATTCCCAAGTTATTCGGTGAGTTATCG
GTTCTACCCAAATCGGTGGATATACGATGGCGGCACTTCGCTGGTATCGAGTATCGAGGCCAGCAGACAATGCCAAGGTT
CAGATATGTCTGCGGTTCTTGAATCCTCACGTGCAACCAACGGAACGCGTGCGCCTGACGGGACATTGTGGGGCGAGTGG
GGGAGCTTGACCGCGTATAGTTCTGATTGGCAATCTGGCGAATATTGGGTCAAAAGGACCAGCACGGATTTTGAAACCAT
GAATATGAACACTGGCGTGCTGCAACCAGGGCCTGCATACTTGGCGTTCCCGCTCTGTGCGCTGTCAATATAA

Upstream 100 bases:

>100_bases
GCCGTAAGTAATCCATAGATGCAAATGTCAGATCGCGATGCGCCTGTTAGGGCGCGGCTGGTAACAGAGCCTTATAGGCG
CATATGAAAAACCTCCGGCT

Downstream 100 bases:

>100_bases
CCAGATAACAGATAGCAATAAGAACAGTTTAATGAGCTGATTATTTGGGGCGCGAATGGGAGTCCGGCAATCCTAGACTC
GTCCTATAAGCAGCAAACGT

Product: invasin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MPEDIYFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSAVAGTRLLAESR
YNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPP
YKRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPASGKTAITVEFTVADFEGKPL
AGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTLAAVPTSIIADG
LMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPI
PDAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVGNTAGDVTITP
QVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFTPNVSVNDQGQV
TITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGTSLVSSIEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEW
GSLTAYSSDWQSGEYWVKRTSTDFETMNMNTGVLQPGPAYLAFPLCALSI

Sequences:

>Translated_690_residues
MPEDIYFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSAVAGTRLLAESR
YNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPP
YKRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPASGKTAITVEFTVADFEGKPL
AGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTLAAVPTSIIADG
LMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPI
PDAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVGNTAGDVTITP
QVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFTPNVSVNDQGQV
TITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGTSLVSSIEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEW
GSLTAYSSDWQSGEYWVKRTSTDFETMNMNTGVLQPGPAYLAFPLCALSI
>Mature_689_residues
PEDIYFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGESFQSQLSPSAVAGTRLLAESRY
NLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVNAQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPPY
KRTAQVSRVTDDLTANFYSLSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPASGKTAITVEFTVADFEGKPLA
GQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKGTIAADKSTLAAVPTSIIADGL
MASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHNDGTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPIP
DAGRSSFTVSTPDILADGTMSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVGNTAGDVTITPQ
VDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNTQYEWSSSFTPNVSVNDQGQVT
ITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGTSLVSSIEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEWG
SLTAYSSDWQSGEYWVKRTSTDFETMNMNTGVLQPGPAYLAFPLCALSI

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=244, Percent_Identity=36.8852459016393, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI145693120, Length=193, Percent_Identity=29.0155440414508, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 73659; Mature: 73528

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS51127 BIG1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEDIYFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGES
CCCCEEECCCCCCCCCEEEECCCCCCCCEEEEECCHHHCCCCCCCCEEEEEEEEEEECHH
FQSQLSPSAVAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVN
HHHHCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCEEEEEEECCCEECCCCCCEEEEE
AQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPPYKRTAQVSRVTDDLTANFYS
EEECCHHHHHHHHCCCCEEEEECCEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEE
LSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPASGKTAITVEFTVADFEGKPL
EEEEEEECCCCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCC
AGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKG
CCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEE
TIAADKSTLAAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHND
EEECCCCHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCC
GTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPIPDAGRSSFTVSTPDILADGT
CEEECCCCCCEEEEEEEEEEECCCEEECCEEEEEEECCCCCCCCCCCEEECCCCCEECCC
MSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVGNTAGDVTITP
HHCCEEEEEECCCCCEEECCCCCCEECCCCCEEEECCCCCCCCEEEEEEECCCCCEEECC
QVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNT
CHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCC
QYEWSSSFTPNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGTS
CEEECCCCCCCEEECCCCCEEEEEEECCEEEEEECCCCCCCEEEEEEECCCCEEECCCHH
LVSSIEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEWGSLTAYSSDWQSGEYWVKRT
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEECCCCCCCCEEEEEC
STDFETMNMNTGVLQPGPAYLAFPLCALSI
CCCCEEEECCCCCCCCCCCHHEEEEHEECC
>Mature Secondary Structure 
PEDIYFGKDNLQRNPYAVTAGINYTPVPLLTVGVDQRMGKSSKHETQWNLQMNYRLGES
CCCEEECCCCCCCCCEEEECCCCCCCCEEEEECCHHHCCCCCCCCEEEEEEEEEEECHH
FQSQLSPSAVAGTRLLAESRYNLVDRNNNIVLEYQKQQVVKLTLSPATISGLPGQVYQVN
HHHHCCCCHHHHHHHHHHCCCCEEECCCCEEEEECCCEEEEEEECCCEECCCCCCEEEEE
AQVQGASAVREIVWSDAELIAAGGTLTPLSTTQFNLVLPPYKRTAQVSRVTDDLTANFYS
EEECCHHHHHHHHCCCCEEEEECCEECCCCCCEEEEEECCCHHHHHHHHHHHHHHCCEEE
LSALAVDHQGNRSNSFTLSVTVQQPQLTLTAAVIGDGAPASGKTAITVEFTVADFEGKPL
EEEEEEECCCCCCCEEEEEEEEECCCEEEEEEEEECCCCCCCCEEEEEEEEEEECCCCCC
AGQEVVITTNNGALPNKITEKTDANGVARIALTNTTDGVTVVTAEVEGQRQSVDTHFVKG
CCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCEEEEEE
TIAADKSTLAAVPTSIIADGLMASTITLELKDTYGDPQAGANVAFDTTLGNMGVITDHND
EEECCCCHHHHCCHHHHHCCCEEEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCC
GTYSAPLTSTTLGVATVTVKVDGAAFSVPSVTVNFTADPIPDAGRSSFTVSTPDILADGT
CEEECCCCCCEEEEEEEEEEECCCEEECCEEEEEEECCCCCCCCCCCEEECCCCCEECCC
MSSTLSFVPVDKNGHFISGMQGLSFTQNGVPVSISPITEQPDSYTATVVGNTAGDVTITP
HHCCEEEEEECCCCCEEECCCCCCEECCCCCEEEECCCCCCCCEEEEEEECCCCCEEECC
QVDTLILSTLQKKISLFPVPTLTGILVNGQNFATDKGFPKTIFKNATFQLQMDNDVANNT
CHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCC
QYEWSSSFTPNVSVNDQGQVTITYQTYSEVAVTAKSKKFPSYSVSYRFYPNRWIYDGGTS
CEEECCCCCCCEEECCCCCEEEEEEECCEEEEEECCCCCCCEEEEEEECCCCEEECCCHH
LVSSIEASRQCQGSDMSAVLESSRATNGTRAPDGTLWGEWGSLTAYSSDWQSGEYWVKRT
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCEEEECCCCCCCCEEEEEC
STDFETMNMNTGVLQPGPAYLAFPLCALSI
CCCCEEEECCCCCCCCCCCHHEEEEHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]