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The map label for this gene is rpiA1 [H]

Identifier: 162419345

GI number: 162419345

Start: 1568400

End: 1569110

Strand: Direct

Name: rpiA1 [H]

Synonym: YpAngola_A1518

Alternate gene names: 162419345

Gene position: 1568400-1569110 (Clockwise)

Preceding gene: 162420766

Following gene: 162421558

Centisome position: 34.82

GC content: 54.71

Gene sequence:

>711_bases
ATGAGCAATCAACAAAATGACGCCAAGAGGGCTGCCGCCCGTCGGGTGATTCAGGATTTCGTGTTCGATGGCATGACGTT
GGGGCTGGGTTCCGGGACCACCTCGCATTTCTTTGTGCGCGAACTGGGCCAGCATGTTGCCAAGGGCTTGCAGTTAACCT
GCACCACAACTTCTCGTGCGACGAGCGAGGTGGCGCGTGACGTGGGCATTGAGCTCTCGGATCCGAATGAGATGAATGAG
ATTGATCTGACCATCGACGGCCCAGATGAGATTGACCGGCGGTTCAATATGATCAAGGGCGGTGGAGCCTGCCTTCTGTG
GGAGAAAATTATCGCCCATGCCTCGAAGCGGATGATTTGTATTTGTGATGAGACAAAAATCGTCAATTGCTTGGGGCAAT
TTCCGCTGCCAGTCGAAATCGTCCCCTTTGCCTGGAAACAGACCGAACGCAGGGTCGAGCGGGTACTCGCGGAACAGGGT
CTCCATCATGTGCCGATTATTCGGCGTATGGGGGGCGGGCACCCGGTGATCACTGACAGTGGAAACTTTATTCTGGATTG
CCATTGCGGGGCGATTATCACGGCCCCTGAACCGCTGGAAATAGAGCTTAATCGCATTCCGGGGGGGGTTGAAAACGGTC
TTTTCACCCGTGAGGCTACCGGTATGGTGGTGGGCTATTTTGACGGTTCCTCCTACGTTCAACTGCGATAA

Upstream 100 bases:

>100_bases
GAGGCCCAACGCATTTACCGTACTCTTTACCCGGCGCTGAGAGAAACCTTCGCAGAACTTGGCGACCCCACCTTTATGTA
GTCATGATCAGGAGTCACGA

Downstream 100 bases:

>100_bases
TCACGGCCTTTTTCGACGCTGTCGCGAGTCGCGTCACCTTGGCACCAAGAGAGCAAAAGAGCAAAAGAGCAAAAGAGCAA
AAGAGCAAAAGAGAGTATCA

Product: ribose 5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A 2; PRI 2 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVARDVGIELSDPNEMNE
IDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQG
LHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGGVENGLFTREATGMVVGYFDGSSYVQLR

Sequences:

>Translated_236_residues
MSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVARDVGIELSDPNEMNE
IDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQG
LHHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGGVENGLFTREATGMVVGYFDGSSYVQLR
>Mature_235_residues
SNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRATSEVARDVGIELSDPNEMNEI
DLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMICICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGL
HHVPIIRRMGGGHPVITDSGNFILDCHCGAIITAPEPLEIELNRIPGGVENGLFTREATGMVVGYFDGSSYVQLR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=232, Percent_Identity=35.3448275862069, Blast_Score=124, Evalue=5e-29,
Organism=Escherichia coli, GI1789280, Length=231, Percent_Identity=37.6623376623377, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=230, Percent_Identity=35.2173913043478, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6324669, Length=245, Percent_Identity=34.2857142857143, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI281364072, Length=222, Percent_Identity=33.7837837837838, Blast_Score=110, Evalue=6e-25,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25992; Mature: 25861

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRA
CCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCHHH
TSEVARDVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMIC
HHHHHHHCCCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
ICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPIIRRMGGGHPVITDS
EECCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEECC
GNFILDCHCGAIITAPEPLEIELNRIPGGVENGLFTREATGMVVGYFDGSSYVQLR
CCEEEEECCCEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCEEEEC
>Mature Secondary Structure 
SNQQNDAKRAAARRVIQDFVFDGMTLGLGSGTTSHFFVRELGQHVAKGLQLTCTTTSRA
CCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCHHH
TSEVARDVGIELSDPNEMNEIDLTIDGPDEIDRRFNMIKGGGACLLWEKIIAHASKRMIC
HHHHHHHCCCEECCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEE
ICDETKIVNCLGQFPLPVEIVPFAWKQTERRVERVLAEQGLHHVPIIRRMGGGHPVITDS
EECCCHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEEEECC
GNFILDCHCGAIITAPEPLEIELNRIPGGVENGLFTREATGMVVGYFDGSSYVQLR
CCEEEEECCCEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]