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The map label for this gene is frwC [H]

Identifier: 162418457

GI number: 162418457

Start: 892557

End: 893651

Strand: Direct

Name: frwC [H]

Synonym: YpAngola_A0866

Alternate gene names: 162418457

Gene position: 892557-893651 (Clockwise)

Preceding gene: 162419077

Following gene: 162418348

Centisome position: 19.82

GC content: 53.97

Gene sequence:

>1095_bases
ATGAAAGAGCTGATAAATATACTTAAAAATACGCGCCAACATCTGATGACGGGCGTTTCATATATGATCCCTTTTGTGGT
TGCTGGCGGTATTTTGCTAGCACTTTCTGTGATGCTTTACGGTAAAGGTGCGGTGCCAGAGGTTGCCAGTGACCCTAATT
TGAAAAAGCTATTCGATATTGGTGTCGTGGGCTTGACGTTGATGGTGCCATTTTTGGCAGCCTATATCGGTTACGCCATT
GCGGATCGTGCGGCGCTCGCCCCGGCGGCTATCGGTGCTTGGGTAGGGGCTTCTTTCGGGGCTGGTTTTTTTGGTGCCAT
TATCGCGGGCTTGCTGGGCGGTATTATCGTTTTCTATCTGAAGAAGATCTCCGTGCCAAAGACGCTGCGTTCGGTGATGC
CGATCTTCGTGATCCCGATCGTCGGTACCCTTCTCACCGCTGGGATCATGATGTGGGGCTTGGGTGAACCCATCGGCATC
CTGACAGCCAACCTCACGCAATGGCTACAGGGTATGCAGCAAGGAAGCGTTATATTACTGGCAATTATTATGGGCCTGAT
GCTGGCGTTTGACATGGGCGGGCCGGTCAACAAGGTGGCTTATGCCTTTATGTTGATCTGTGTGGCGCAGGGTGTTTATA
CCTTGGTGGCCGTCGCCGTCGCCGTCGCCGCCGTCGCCATTGCAACCCCGCCGTTGGGCATGGGCCTTGCCACGCTGATT
GACCGTAAATATTACTCGGTGGAAGAACGTGAAGCAGGTAAGGCCGCGATGCTGATGGGCTGCGTTGGCATTACTGAGGG
GGCCATCCCGTTTGCCGCCGCCGATCCACTGCGTGTCATTCCTGCCAATATGATCGGTTCCGCCTGCGCCGCCGTAACTG
CCGTGTTGTTCGGTGTCCAGTGCTATGCCGCTTGGGGAGGGTTGATCGTGCTACCGGTGGTCGACGGTAAACTGGGCTTT
GTGGTGGCCTTGTTAGTCGGCATGGTCGTTACCGCGTTGATAGCCAATCTATTAAAGCGTTTCACCGCCCAAAAGCAGCC
GGGAAGGTCATCAGCAGAGGGCGATGTGAACATGGATTTCGATATTAAAAATTAG

Upstream 100 bases:

>100_bases
CCAACAGCATCAAAAACATTTCGCGATTTCAATATTAAGGGGAATAAGCCCTGACGCCTGCGGAACTCATCGCACACGGA
TGAACGCTATGGAGTGAATG

Downstream 100 bases:

>100_bases
CGGTACACCCGATGAGCGTTATTTATTTTAAGGTCAACGACATTTTAAGGTCAACAACCGGTAAGTGATTCGGGCGAGTG
AGCGCAGCTAACACCCCTGT

Product: putative fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAVAVAAVAIATPPLGMGLATLI
DRKYYSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGF
VVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN

Sequences:

>Translated_364_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAVAVAAVAIATPPLGMGLATLI
DRKYYSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGF
VVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN
>Mature_364_residues
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDIGVVGLTLMVPFLAAYIGYAI
ADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYLKKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGI
LTANLTQWLQGMQQGSVILLAIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAVAVAAVAIATPPLGMGLATLI
DRKYYSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQCYAAWGGLIVLPVVDGKLGF
VVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDFDIKN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=363, Percent_Identity=75.2066115702479, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1788492, Length=333, Percent_Identity=40.5405405405405, Blast_Score=218, Evalue=7e-58,
Organism=Escherichia coli, GI1786951, Length=282, Percent_Identity=36.8794326241135, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI87082348, Length=302, Percent_Identity=36.4238410596026, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788729, Length=376, Percent_Identity=26.063829787234, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37851; Mature: 37851

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVVGLTLMVPFLAAYIGYAIADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGILTANLTQWLQGMQQGSVILL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAVAVAAVAIATPPLGMGLATLI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DRKYYSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQ
HHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
CYAAWGGLIVLPVVDGKLGFVVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDF
HHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DIKN
EECC
>Mature Secondary Structure
MKELINILKNTRQHLMTGVSYMIPFVVAGGILLALSVMLYGKGAVPEVASDPNLKKLFDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
GVVGLTLMVPFLAAYIGYAIADRAALAPAAIGAWVGASFGAGFFGAIIAGLLGGIIVFYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKISVPKTLRSVMPIFVIPIVGTLLTAGIMMWGLGEPIGILTANLTQWLQGMQQGSVILL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHH
AIIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTLVAVAVAVAAVAIATPPLGMGLATLI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
DRKYYSVEEREAGKAAMLMGCVGITEGAIPFAAADPLRVIPANMIGSACAAVTAVLFGVQ
HHHHHCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH
CYAAWGGLIVLPVVDGKLGFVVALLVGMVVTALIANLLKRFTAQKQPGRSSAEGDVNMDF
HHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DIKN
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]