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The map label for this gene is zntR [H]

Identifier: 162418390

GI number: 162418390

Start: 618941

End: 619375

Strand: Direct

Name: zntR [H]

Synonym: YpAngola_A0608

Alternate gene names: 162418390

Gene position: 618941-619375 (Clockwise)

Preceding gene: 162419495

Following gene: 162421083

Centisome position: 13.74

GC content: 45.29

Gene sequence:

>435_bases
GTGGACAATATGTTAAAAATCGGGCAGTTAGCTAAACTTGCTGATGTAACGCCGGATACTATCCGTTACTACGAAAAGCA
GGGAATGATGGATCACGGTGAACGAACTGATGGTGGCTACCGGCTGTATACTGATCAGGACCTTCAGCGTTTACGGTTTA
TCCGCTACGCCAAGCAACTAGGCTTTACATTGGATACTATCGCAGAATTATTGTCGATCCGGATAGATCCTGACCATCAT
ACCTGCCAGGAGTCCAAGTCTATTGTAGATTCACGGCTTAGTGATGTGGAAGGTAAGATCAGAGAATTAGAGAGAATGCG
TGATTCCCTAAAAAGACTCAGCGAGGCTTGTTGTGGCACTAGTCATGCGACGACATACTGCTCAATATTGGAAGCTTTGG
AGCAGGGGGCAACAGAAGAGTTAATTAAGGTATGA

Upstream 100 bases:

>100_bases
TTGATTATCATGAGATTTTTTCTTAATGAGGTCTGTAACATGATGACTTCCAACTCCTTATTTTATACGCTGTTGATTAT
CAACAGGAATTGGCTGGTAG

Downstream 100 bases:

>100_bases
ATTTCTCTACAGAGGGTTTAAATCGGCAGAGGGCCACCGTATTATGTTCAGGATTTATCCATAGCGTCATTACTACGAGG
TAGCACCATGACAACATATC

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDNMLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHH
TCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV

Sequences:

>Translated_144_residues
MDNMLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHH
TCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV
>Mature_144_residues
MDNMLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHH
TCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=135, Percent_Identity=69.6296296296296, Blast_Score=209, Evalue=8e-56,
Organism=Escherichia coli, GI1786695, Length=129, Percent_Identity=35.6589147286822, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16489; Mature: 16489

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNMLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
GFTLDTIAELLSIRIDPDHHTCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHATTYCSILEALEQGATEELIKV
CHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MDNMLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQL
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
GFTLDTIAELLSIRIDPDHHTCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGT
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHATTYCSILEALEQGATEELIKV
CHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]