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The map label for this gene is gdhA [H]

Identifier: 162149047

GI number: 162149047

Start: 3367325

End: 3369742

Strand: Direct

Name: gdhA [H]

Synonym: GDI_3277

Alternate gene names: 162149047

Gene position: 3367325-3369742 (Clockwise)

Preceding gene: 162149046

Following gene: 162149049

Centisome position: 85.37

GC content: 68.03

Gene sequence:

>2418_bases
ATGAATATTAAACAAGGGTTGCGGCCCGTGCTCGCGATCACCGCTGTAGTCTATGCCTTGGTCGGGCTGTATTTGCTGGC
GGGGGGCATCTGGCTGACCGCTCTGGGCGGATCGCTCTACTACCTCATTGCCGGCGCTCTACTGCTGGTGACGGCAGTAC
TGCTGCTGCGCCGCCGGCAGGAGGCCCTATGGGTCTACGCGGCCCTGCTGATCGGCACCATGGTCTGGGCCGTGGGTGAG
GTCGGGCTCGATTTCTGGGCGCTGGCACCGCGCGGCGACATCCTGGTTCCGCTGGGCATCTGGCTGATGCTGCCGCCCAT
TACCCGCAACCTGGGCACCCGCAACCTGGGCACGCGCGACCTGGCGCCGCCCAGCCGGGCCGCCCAGGTGCCGCTGGGCC
TGGCCGTGGGCGCGGCCGTGGTCGTGGTCGTCGCCGCCCTGACGCAGGACCCGCAGGATATCGCGGGCAGCCTGCCCCAG
GTCGCGCAGAACGCCCCCACCCCGGGCGATGCCGGCGAAATCCCGGACGAGGACTGGCAGGCCTACGGCCGCACCGGCTT
CGGCGACCGGTTCAGCCCGCTGAAGCAGATCACGCCGGACAACGTGCATAACCTGAAGGTGGCCTGGACCTTCCGCACCG
GCGATGTGAAGGGCCCGCACGATCCGGGCGAGTTCACGGACGAAACGACGCCGATCAAGATCCGCGACACCGTGTATCTG
TGCTCGCCGCACCAGATCCTGTTCGCGCTGGACGCCGCCACGGGCAAGCTGAAGTGGAAGTTCGACCCCAAGCTGACCTA
TAATTCCACCTTCCAGCACATGACCTGCCGCGGCGTGTCGTACCACGAGACCGCGCAGGGGGCCGAGACGATCGACGGGG
CGCAGGCGCCGGTCGATTGCGGACACCGCATCTTCCTGCCCACCAATGACGGGCGCCTGTTCGCCCTGGACGCCGAAACC
GGCGAACGCTGCCACAATTTCGGCGATGACGGCATGGTGGACCTGAAGGCCGGCGAAGTCGTCAAGACGGCCGGCTTCTT
CGAAGCGACCTCGCCGCCGGTCGTCACCGACAAGATGGTGATCGTCTCCGGCGCGGTGATGGACAATTACTCGACGCACG
AACCCTCGGGCGTCACGCGCGGCTTCGACGTCTATACCGGCCGGCTGGTCTGGGTGTTCGACGCGGGCAATCCGGACCCG
AACGAAATGCCGTCCGACACCCACCATTTCGTCGGCAATTCGCCCAATTCGTGGATCGTGTCGTCCTACGACCCCAAGCT
GAACCTGATCTTCATCCCGATGGGCGTGCAGACGCCGGACATCTGGGGCGGCAATCGCGGGGCGGACGCCGAACGCTATG
CCAGCTCGATCCTGGCGCTGAACGCCGATACCGGCAAGCTGGCCTGGTCGTACCAGACCGTGCACCATGACCTTTGGGAC
ATGGACATCCCGGCCCAGCCCAGCCTGGTGGACGTCCGCACCGCCGGCGGCGACATCGTCCCCGCGCTGTACGCCCCGGC
CAAGACCGGCAACATCTTCGTCCTGGACCGCCGCACCGGCACCCCGATCGTGCCGGCGCCCGAAACGCGGGTGCCCCAGG
GCCCGGCCCCGGGCGACCACCTTTCGCCCACGCAGCCCTTCTCGGAGCTGACCTTCCGCCCCAAGAACAACCTGACGGGC
GCGGACATGTGGGGCGGCACCATGTTCGACCAGCTGATGTGCCGGATCATGTTCCACCAGCTTCGCTATGACGGGCCGTT
CACCCCGCCGTCGCTGCAGGGCACGCTGGTGTTCCCGGGCAACCTGGGCATGTTCGAATGGGGCGGGCTGGCCGTCGATC
CGGTGCGCCAGATCGCCATCGCCAACCCGATCGCGATCCCGTTCGTCTCGCGCCTGATCCCGCGCGGCCCGAACAACCCG
GCGTCGCCCGACGCCTCGCAGCCCTCGGGCTCGGAAACGGGGGTGCAGCCGATGTTCGGCGTGCCGTACGGCGTGACGCT
CAGCCCGTTCCTGTCGCCGCTGGGCCTGCCGTGCAAGAAGCCGGCCTGGGGCTTCATGGCCGGGATCGACCTGAAGACCA
ACACCATCGTGTGGATGCACCGCAACGGCACGATCCGCGACAGCGCGCCGCTGCCGATCCCCTTCAAGCTGGGCGTGCCC
AGCCTGGGCGGACCGCTGACGACGGCGGGTGGCGTGGCCTTCCTGACCTCGACGGCGGATTTCTATATCCGCGCGTATGA
CGTCACCACGGGCCGCCAGCTCTGGCAGGACCGCCTGCCGGCGGGTGGCCAGTCCACGCCGATGACCTACGCCGTGGGTG
GCCGCCAGTTCATCGTGACGGCCGATGGCGGTCACGGGTCGTTCGGCACCAAGCTGGGCGATTACGTGGTGGCCTACGCC
CTGCCCGAAGCCCACTGA

Upstream 100 bases:

>100_bases
CCGGGTGCGTCGCCGCCTTGGCTCATCAGCTTGACCCGCCAAGGCGGAATGGTCTTGTCAACGAGTTTGCATTTGCCCCC
AACATTTATTCAGGACGTCT

Downstream 100 bases:

>100_bases
CGCATACCCCGCCCGCGATCCCCCGGATTGCGGGCGGGCCTATCTATCGGATATGTGAAGACATTCATCCCGGACGGGTG
ATGCTTTCCCCCCTTCGGTC

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MNIKQGLRPVLAITAVVYALVGLYLLAGGIWLTALGGSLYYLIAGALLLVTAVLLLRRRQEALWVYAALLIGTMVWAVGE
VGLDFWALAPRGDILVPLGIWLMLPPITRNLGTRNLGTRDLAPPSRAAQVPLGLAVGAAVVVVVAALTQDPQDIAGSLPQ
VAQNAPTPGDAGEIPDEDWQAYGRTGFGDRFSPLKQITPDNVHNLKVAWTFRTGDVKGPHDPGEFTDETTPIKIRDTVYL
CSPHQILFALDAATGKLKWKFDPKLTYNSTFQHMTCRGVSYHETAQGAETIDGAQAPVDCGHRIFLPTNDGRLFALDAET
GERCHNFGDDGMVDLKAGEVVKTAGFFEATSPPVVTDKMVIVSGAVMDNYSTHEPSGVTRGFDVYTGRLVWVFDAGNPDP
NEMPSDTHHFVGNSPNSWIVSSYDPKLNLIFIPMGVQTPDIWGGNRGADAERYASSILALNADTGKLAWSYQTVHHDLWD
MDIPAQPSLVDVRTAGGDIVPALYAPAKTGNIFVLDRRTGTPIVPAPETRVPQGPAPGDHLSPTQPFSELTFRPKNNLTG
ADMWGGTMFDQLMCRIMFHQLRYDGPFTPPSLQGTLVFPGNLGMFEWGGLAVDPVRQIAIANPIAIPFVSRLIPRGPNNP
ASPDASQPSGSETGVQPMFGVPYGVTLSPFLSPLGLPCKKPAWGFMAGIDLKTNTIVWMHRNGTIRDSAPLPIPFKLGVP
SLGGPLTTAGGVAFLTSTADFYIRAYDVTTGRQLWQDRLPAGGQSTPMTYAVGGRQFIVTADGGHGSFGTKLGDYVVAYA
LPEAH

Sequences:

>Translated_805_residues
MNIKQGLRPVLAITAVVYALVGLYLLAGGIWLTALGGSLYYLIAGALLLVTAVLLLRRRQEALWVYAALLIGTMVWAVGE
VGLDFWALAPRGDILVPLGIWLMLPPITRNLGTRNLGTRDLAPPSRAAQVPLGLAVGAAVVVVVAALTQDPQDIAGSLPQ
VAQNAPTPGDAGEIPDEDWQAYGRTGFGDRFSPLKQITPDNVHNLKVAWTFRTGDVKGPHDPGEFTDETTPIKIRDTVYL
CSPHQILFALDAATGKLKWKFDPKLTYNSTFQHMTCRGVSYHETAQGAETIDGAQAPVDCGHRIFLPTNDGRLFALDAET
GERCHNFGDDGMVDLKAGEVVKTAGFFEATSPPVVTDKMVIVSGAVMDNYSTHEPSGVTRGFDVYTGRLVWVFDAGNPDP
NEMPSDTHHFVGNSPNSWIVSSYDPKLNLIFIPMGVQTPDIWGGNRGADAERYASSILALNADTGKLAWSYQTVHHDLWD
MDIPAQPSLVDVRTAGGDIVPALYAPAKTGNIFVLDRRTGTPIVPAPETRVPQGPAPGDHLSPTQPFSELTFRPKNNLTG
ADMWGGTMFDQLMCRIMFHQLRYDGPFTPPSLQGTLVFPGNLGMFEWGGLAVDPVRQIAIANPIAIPFVSRLIPRGPNNP
ASPDASQPSGSETGVQPMFGVPYGVTLSPFLSPLGLPCKKPAWGFMAGIDLKTNTIVWMHRNGTIRDSAPLPIPFKLGVP
SLGGPLTTAGGVAFLTSTADFYIRAYDVTTGRQLWQDRLPAGGQSTPMTYAVGGRQFIVTADGGHGSFGTKLGDYVVAYA
LPEAH
>Mature_805_residues
MNIKQGLRPVLAITAVVYALVGLYLLAGGIWLTALGGSLYYLIAGALLLVTAVLLLRRRQEALWVYAALLIGTMVWAVGE
VGLDFWALAPRGDILVPLGIWLMLPPITRNLGTRNLGTRDLAPPSRAAQVPLGLAVGAAVVVVVAALTQDPQDIAGSLPQ
VAQNAPTPGDAGEIPDEDWQAYGRTGFGDRFSPLKQITPDNVHNLKVAWTFRTGDVKGPHDPGEFTDETTPIKIRDTVYL
CSPHQILFALDAATGKLKWKFDPKLTYNSTFQHMTCRGVSYHETAQGAETIDGAQAPVDCGHRIFLPTNDGRLFALDAET
GERCHNFGDDGMVDLKAGEVVKTAGFFEATSPPVVTDKMVIVSGAVMDNYSTHEPSGVTRGFDVYTGRLVWVFDAGNPDP
NEMPSDTHHFVGNSPNSWIVSSYDPKLNLIFIPMGVQTPDIWGGNRGADAERYASSILALNADTGKLAWSYQTVHHDLWD
MDIPAQPSLVDVRTAGGDIVPALYAPAKTGNIFVLDRRTGTPIVPAPETRVPQGPAPGDHLSPTQPFSELTFRPKNNLTG
ADMWGGTMFDQLMCRIMFHQLRYDGPFTPPSLQGTLVFPGNLGMFEWGGLAVDPVRQIAIANPIAIPFVSRLIPRGPNNP
ASPDASQPSGSETGVQPMFGVPYGVTLSPFLSPLGLPCKKPAWGFMAGIDLKTNTIVWMHRNGTIRDSAPLPIPFKLGVP
SLGGPLTTAGGVAFLTSTADFYIRAYDVTTGRQLWQDRLPAGGQSTPMTYAVGGRQFIVTADGGHGSFGTKLGDYVVAYA
LPEAH

Specific function: Gdh Is Probably Involved In Energy Conservation Rather Than In Sugar Metabolism. [C]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=802, Percent_Identity=60.4738154613466, Blast_Score=954, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 86507; Mature: 86507

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKQGLRPVLAITAVVYALVGLYLLAGGIWLTALGGSLYYLIAGALLLVTAVLLLRRRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHH
EALWVYAALLIGTMVWAVGEVGLDFWALAPRGDILVPLGIWLMLPPITRNLGTRNLGTRD
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHCCCCHHHCCCCCCCCCCC
LAPPSRAAQVPLGLAVGAAVVVVVAALTQDPQDIAGSLPQVAQNAPTPGDAGEIPDEDWQ
CCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCCCCCCCCCCHHHH
AYGRTGFGDRFSPLKQITPDNVHNLKVAWTFRTGDVKGPHDPGEFTDETTPIKIRDTVYL
HHCCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEE
CSPHQILFALDAATGKLKWKFDPKLTYNSTFQHMTCRGVSYHETAQGAETIDGAQAPVDC
ECCCEEEEEEECCCCEEEEEECCCEEECCCCCEEEECCCCHHHHCCCCHHCCCCCCCCCC
GHRIFLPTNDGRLFALDAETGERCHNFGDDGMVDLKAGEVVKTAGFFEATSPPVVTDKMV
CCEEEEECCCCEEEEEECCCCHHHHCCCCCCEEEECCCCEEEECCCCCCCCCCCEECCEE
IVSGAVMDNYSTHEPSGVTRGFDVYTGRLVWVFDAGNPDPNEMPSDTHHFVGNSPNSWIV
EEEEEEECCCCCCCCCCCCCCCEEEECEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEE
SSYDPKLNLIFIPMGVQTPDIWGGNRGADAERYASSILALNADTGKLAWSYQTVHHDLWD
EECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCEEEEEECCCCCEEEEEEHHHHHHCC
MDIPAQPSLVDVRTAGGDIVPALYAPAKTGNIFVLDRRTGTPIVPAPETRVPQGPAPGDH
CCCCCCCCEEEEECCCCCEEEHEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
LSPTQPFSELTFRPKNNLTGADMWGGTMFDQLMCRIMFHQLRYDGPFTPPSLQGTLVFPG
CCCCCCHHHCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
NLGMFEWGGLAVDPVRQIAIANPIAIPFVSRLIPRGPNNPASPDASQPSGSETGVQPMFG
CCCCEECCCEECCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VPYGVTLSPFLSPLGLPCKKPAWGFMAGIDLKTNTIVWMHRNGTIRDSAPLPIPFKLGVP
CCCCCCHHHHHHHCCCCCCCCCCCEEEECEECCCEEEEEECCCCCCCCCCCCEEEECCCC
SLGGPLTTAGGVAFLTSTADFYIRAYDVTTGRQLWQDRLPAGGQSTPMTYAVGGRQFIVT
CCCCCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEECCEEEEEE
ADGGHGSFGTKLGDYVVAYALPEAH
ECCCCCCCCCHHHCEEEEEECCCCC
>Mature Secondary Structure
MNIKQGLRPVLAITAVVYALVGLYLLAGGIWLTALGGSLYYLIAGALLLVTAVLLLRRRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHH
EALWVYAALLIGTMVWAVGEVGLDFWALAPRGDILVPLGIWLMLPPITRNLGTRNLGTRD
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHCCCCHHHCCCCCCCCCCC
LAPPSRAAQVPLGLAVGAAVVVVVAALTQDPQDIAGSLPQVAQNAPTPGDAGEIPDEDWQ
CCCCCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHCCCCCCCCCCCCCHHHH
AYGRTGFGDRFSPLKQITPDNVHNLKVAWTFRTGDVKGPHDPGEFTDETTPIKIRDTVYL
HHCCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEE
CSPHQILFALDAATGKLKWKFDPKLTYNSTFQHMTCRGVSYHETAQGAETIDGAQAPVDC
ECCCEEEEEEECCCCEEEEEECCCEEECCCCCEEEECCCCHHHHCCCCHHCCCCCCCCCC
GHRIFLPTNDGRLFALDAETGERCHNFGDDGMVDLKAGEVVKTAGFFEATSPPVVTDKMV
CCEEEEECCCCEEEEEECCCCHHHHCCCCCCEEEECCCCEEEECCCCCCCCCCCEECCEE
IVSGAVMDNYSTHEPSGVTRGFDVYTGRLVWVFDAGNPDPNEMPSDTHHFVGNSPNSWIV
EEEEEEECCCCCCCCCCCCCCCEEEECEEEEEEECCCCCCCCCCCCCHHHCCCCCCCEEE
SSYDPKLNLIFIPMGVQTPDIWGGNRGADAERYASSILALNADTGKLAWSYQTVHHDLWD
EECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHCEEEEEECCCCCEEEEEEHHHHHHCC
MDIPAQPSLVDVRTAGGDIVPALYAPAKTGNIFVLDRRTGTPIVPAPETRVPQGPAPGDH
CCCCCCCCEEEEECCCCCEEEHEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCC
LSPTQPFSELTFRPKNNLTGADMWGGTMFDQLMCRIMFHQLRYDGPFTPPSLQGTLVFPG
CCCCCCHHHCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
NLGMFEWGGLAVDPVRQIAIANPIAIPFVSRLIPRGPNNPASPDASQPSGSETGVQPMFG
CCCCEECCCEECCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
VPYGVTLSPFLSPLGLPCKKPAWGFMAGIDLKTNTIVWMHRNGTIRDSAPLPIPFKLGVP
CCCCCCHHHHHHHCCCCCCCCCCCEEEECEECCCEEEEEECCCCCCCCCCCCEEEECCCC
SLGGPLTTAGGVAFLTSTADFYIRAYDVTTGRQLWQDRLPAGGQSTPMTYAVGGRQFIVT
CCCCCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHCCCCCCCCCEEEEECCEEEEEE
ADGGHGSFGTKLGDYVVAYALPEAH
ECCCCCCCCCHHHCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1833618 [H]