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The map label for this gene is engA [H]

Identifier: 162149029

GI number: 162149029

Start: 3349704

End: 3351143

Strand: Reverse

Name: engA [H]

Synonym: GDI_3259

Alternate gene names: 162149029

Gene position: 3351143-3349704 (Counterclockwise)

Preceding gene: 162149030

Following gene: 162149026

Centisome position: 84.96

GC content: 70.21

Gene sequence:

>1440_bases
TTGGCCAAGCTTCCTTCCGTTCCGACCGGGGACGACCTGCCGGTGGTGGTCATCGCCGGTCGTCCGAATGTCGGTAAATC
GACCCTGTTCAACCGCCTTGTGGGGCGGCGGCAGGCGCTGGTTGCCGATACCCCCGGCGTGACCCGCGACCGCAAGGAAG
CCGAGACCGTGATGCGCGGCCGCCGGGTGCGCCTGGTCGATACGGCGGGGCTGGAGGAAGCGGCGGCCGATACGCTGTAC
GGCCGCATGCGGGCATCGTCGGAATCGGCGGTGGCGCAGGCGGACCTGGTCCTGTTCTGCATCGACACCCGCGCGGGCAT
CACCCCGGCCGACGAGCATTTCGCGGCATGGCTGCGCCGCCAGGGGCGCCCCGTGCTGCTGATCGCCAACAAGGCCGAGG
GACGGCAGGGGGCGGCGGCGGCGATGGAGGCCTTCGCCCTGGGGCTGGGCACGCCGCTGGCCATTTCCGCCGAACATGGC
GAAGGCCTGTCGGACCTGATGGGCGAGATCGCGGACCGCCTGCCGCCGCAGGCTCCGGCTCTCGTCGCCGGGGGCATGGC
GGACGCGGCGTTCGAAGACGATGACGCGGAAGCGGGCGAGGCTGACGAAGACGACCGTCCCGTCGGTCCGCTGCGCCTGG
CCATCGTCGGGCGGCCGAATGCCGGAAAATCGACCCTGCTGAACCGCCTGCTGGGCGAGGAGCGGATGATCACCGGGCCC
GAGCCGGGCCTGACCCGCGATTCGGTGACGGTGCTGCTGCATGACGAGCATGGGCCGATTCAACTGGTCGATACGGCGGG
GCTGCGCCGCCGGGGCCGGATCGAGGAATCGCTGGAGAAGATGTCGGTTTCCGCCACCATCGAGGCACTGAAGATGGCCG
AGGTGGTGGTCCTGACGCTGGACGCGACCCTGGGCGTGCATGAACAGGACCTGCAGATCGCCCGCCTGATCGAGCGCGAG
GGCCGGTGCTGCGTCCTGGCGCTGAACAAGTGGGACGCGGTCGAGGACCGGATCGCGACACGGCAGGCGATCTCCGACCG
GATCGAGACGTCGCTGGCGCAGATGCGCGGCATTCCGGTCGTTTCGTTCTCGGCGCTGACCGGGGCCGGGGTAAACAAGC
TGCTGCCGGTGGTGCGCCGGGCCCATGCGACCTGGAACAAGCGGGTTCCGACCGGGGCGCTGAACCGCTGGTTCGAGGCG
ATGCTGGAGCGGCACAGCCCGCCGCTGGTCAGCGGGCGGCGGCTGAAGCTGCGCTACATGACGCAGGCCAAGGCCCGGCC
GCCGACCTTCATCCTGTTCGGCACCCGGGCCGAGCAACTGCCCGAGGATTACCAGCGCTACCTGGTCAACGGCCTGCGCG
AGACGTTCGACCTGCCCGGCACGCCGATCCGGCTGCTGCTGCGCGGGACCAAGAACCCCTACGCCGAAGGGCAGGGGTAA

Upstream 100 bases:

>100_bases
GGGGGTGGCCAGCGTGGCGCCGATCGTGGTCGATGGACGGCTGCTGATCGTGACCGACGACGGTCACCTGATTGCCTATA
GCTAAGGATATCGTTGAAAA

Downstream 100 bases:

>100_bases
CAGGCAGGGGTACGAGGGGGCAGGCGCCCCCTCAGTGGATCACCAGCGACAGCAGCAGGCAGAACACCAGCCCCAGGACG
GCGATCAGGGTTTCGATGAC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MAKLPSVPTGDDLPVVVIAGRPNVGKSTLFNRLVGRRQALVADTPGVTRDRKEAETVMRGRRVRLVDTAGLEEAAADTLY
GRMRASSESAVAQADLVLFCIDTRAGITPADEHFAAWLRRQGRPVLLIANKAEGRQGAAAAMEAFALGLGTPLAISAEHG
EGLSDLMGEIADRLPPQAPALVAGGMADAAFEDDDAEAGEADEDDRPVGPLRLAIVGRPNAGKSTLLNRLLGEERMITGP
EPGLTRDSVTVLLHDEHGPIQLVDTAGLRRRGRIEESLEKMSVSATIEALKMAEVVVLTLDATLGVHEQDLQIARLIERE
GRCCVLALNKWDAVEDRIATRQAISDRIETSLAQMRGIPVVSFSALTGAGVNKLLPVVRRAHATWNKRVPTGALNRWFEA
MLERHSPPLVSGRRLKLRYMTQAKARPPTFILFGTRAEQLPEDYQRYLVNGLRETFDLPGTPIRLLLRGTKNPYAEGQG

Sequences:

>Translated_479_residues
MAKLPSVPTGDDLPVVVIAGRPNVGKSTLFNRLVGRRQALVADTPGVTRDRKEAETVMRGRRVRLVDTAGLEEAAADTLY
GRMRASSESAVAQADLVLFCIDTRAGITPADEHFAAWLRRQGRPVLLIANKAEGRQGAAAAMEAFALGLGTPLAISAEHG
EGLSDLMGEIADRLPPQAPALVAGGMADAAFEDDDAEAGEADEDDRPVGPLRLAIVGRPNAGKSTLLNRLLGEERMITGP
EPGLTRDSVTVLLHDEHGPIQLVDTAGLRRRGRIEESLEKMSVSATIEALKMAEVVVLTLDATLGVHEQDLQIARLIERE
GRCCVLALNKWDAVEDRIATRQAISDRIETSLAQMRGIPVVSFSALTGAGVNKLLPVVRRAHATWNKRVPTGALNRWFEA
MLERHSPPLVSGRRLKLRYMTQAKARPPTFILFGTRAEQLPEDYQRYLVNGLRETFDLPGTPIRLLLRGTKNPYAEGQG
>Mature_478_residues
AKLPSVPTGDDLPVVVIAGRPNVGKSTLFNRLVGRRQALVADTPGVTRDRKEAETVMRGRRVRLVDTAGLEEAAADTLYG
RMRASSESAVAQADLVLFCIDTRAGITPADEHFAAWLRRQGRPVLLIANKAEGRQGAAAAMEAFALGLGTPLAISAEHGE
GLSDLMGEIADRLPPQAPALVAGGMADAAFEDDDAEAGEADEDDRPVGPLRLAIVGRPNAGKSTLLNRLLGEERMITGPE
PGLTRDSVTVLLHDEHGPIQLVDTAGLRRRGRIEESLEKMSVSATIEALKMAEVVVLTLDATLGVHEQDLQIARLIEREG
RCCVLALNKWDAVEDRIATRQAISDRIETSLAQMRGIPVVSFSALTGAGVNKLLPVVRRAHATWNKRVPTGALNRWFEAM
LERHSPPLVSGRRLKLRYMTQAKARPPTFILFGTRAEQLPEDYQRYLVNGLRETFDLPGTPIRLLLRGTKNPYAEGQG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=479, Percent_Identity=40.0835073068894, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI2367268, Length=158, Percent_Identity=38.6075949367089, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788919, Length=171, Percent_Identity=32.1637426900585, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=170, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51954; Mature: 51823

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLPSVPTGDDLPVVVIAGRPNVGKSTLFNRLVGRRQALVADTPGVTRDRKEAETVMRG
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCC
RRVRLVDTAGLEEAAADTLYGRMRASSESAVAQADLVLFCIDTRAGITPADEHFAAWLRR
CEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHH
QGRPVLLIANKAEGRQGAAAAMEAFALGLGTPLAISAEHGEGLSDLMGEIADRLPPQAPA
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC
LVAGGMADAAFEDDDAEAGEADEDDRPVGPLRLAIVGRPNAGKSTLLNRLLGEERMITGP
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCC
EPGLTRDSVTVLLHDEHGPIQLVDTAGLRRRGRIEESLEKMSVSATIEALKMAEVVVLTL
CCCCCCCCEEEEEECCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEE
DATLGVHEQDLQIARLIEREGRCCVLALNKWDAVEDRIATRQAISDRIETSLAQMRGIPV
ECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VSFSALTGAGVNKLLPVVRRAHATWNKRVPTGALNRWFEAMLERHSPPLVSGRRLKLRYM
EEEHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TQAKARPPTFILFGTRAEQLPEDYQRYLVNGLRETFDLPGTPIRLLLRGTKNPYAEGQG
HHCCCCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AKLPSVPTGDDLPVVVIAGRPNVGKSTLFNRLVGRRQALVADTPGVTRDRKEAETVMRG
CCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCC
RRVRLVDTAGLEEAAADTLYGRMRASSESAVAQADLVLFCIDTRAGITPADEHFAAWLRR
CEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHH
QGRPVLLIANKAEGRQGAAAAMEAFALGLGTPLAISAEHGEGLSDLMGEIADRLPPQAPA
CCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCC
LVAGGMADAAFEDDDAEAGEADEDDRPVGPLRLAIVGRPNAGKSTLLNRLLGEERMITGP
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCC
EPGLTRDSVTVLLHDEHGPIQLVDTAGLRRRGRIEESLEKMSVSATIEALKMAEVVVLTL
CCCCCCCCEEEEEECCCCCEEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEE
DATLGVHEQDLQIARLIEREGRCCVLALNKWDAVEDRIATRQAISDRIETSLAQMRGIPV
ECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VSFSALTGAGVNKLLPVVRRAHATWNKRVPTGALNRWFEAMLERHSPPLVSGRRLKLRYM
EEEHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TQAKARPPTFILFGTRAEQLPEDYQRYLVNGLRETFDLPGTPIRLLLRGTKNPYAEGQG
HHCCCCCCEEEEECCCHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA