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The map label for this gene is gntT [H]

Identifier: 162149028

GI number: 162149028

Start: 3348329

End: 3349672

Strand: Direct

Name: gntT [H]

Synonym: GDI_3258

Alternate gene names: 162149028

Gene position: 3348329-3349672 (Clockwise)

Preceding gene: 162149027

Following gene: 162149036

Centisome position: 84.89

GC content: 67.41

Gene sequence:

>1344_bases
ATGTCCTCACTTCTTGCCGTTTCCCTGGCGACCGCCGCCATCGTGGCCGTCGTGCTCCTGATCGGGCGCTATAAACTCAA
CCCCTTCATCGTGCTGCTGTGCGTGTCGCTGCTGCTGGCCCTGTGCGCCGGCATGCCGCCGCAGAAGGCCGTCACGTCGT
TCGAGGCCGGCGCCGGCCACGTGCTGGGCCATATCGCCACCGTGATCGCGCTGGGGACGATGCTGGGCAAGATGCTGGCC
GAATCCGGCGGCGCGGACCAGATCGCGCTGACGATCACCCGCGTCGCGGGCAAGGGCCGGATCAGTTGGGCCATGATGGT
CATCGGCCTGCTGATCGGCCTGCCGGTGTTCTTCGAGGTCGGCTTCGTGCTGCTGATTCCGCTGGTCTTCACCCTGGCGC
GGCGGACATCGACCCCCATGCTGCTGCTGGCGCTGCCGATGGGCGCCGCCCTGTCGGTCACCCACGCGATGATCCCGCCC
CATCCGGCCACCCTGCTGGCGCTGTCGGCCTATCACGCCGATACCGGGCGGACGATCTTCTGGGGGGTCATCATCGGTAC
GCCGATCGCGGCCCTGGCCGGCCCGATCTATGCGAAATTCATCACGCCGCGCATCCAGATCGCCGGCCATGCCGGGCTGG
AAGACCAGTTCGCGAGCAAGGACGTCCACGAGAACCTGCCGCCGTTCAGTATCACGGTGCTGACGATCCTCTCGCCGGTC
CTGCTGATGCTGCTGGGTTCGGTCGCCGACCTGGTCTCGCAACCCGGCAGCACGGCGAACACCATCCTGCATTTCATCGG
CAATACCGACATCGCCCTGCTGCTGGCGACGATCCTGTCCTTCTACGTGCTGGGCCTGGCCCGCGGCTTCTCGCGCGAGA
CGATCCTGCGCTTCACCAACGAATGCCTGGGGCCCACCGCGCTGATCATGCTGCTGGTGGGCGCGGGCGGCGGCTTCGGC
CGCGAACTGGTCGATAGCGGGGTGTCGAAGGCCATCACAGACCTGGCGCTGGGGGCGCATGTGCCGCTGCTGGTGCTGGC
CTGGCTGCTGGCGGTGGTGGTGCGCGTGGCCGCCGGGTCCGCCACCGTGGCCATGAGCACGGCGTCCGGCATCGTCGGGC
CGATCCTGCTGCACAGCCACGGCACGTCGCCGGAACTGATGGTGCTGGTCACCGGGGCCGGATCGGTGGCGCTGGGGCCG
ATGAACGACGCCGGGTTCTGGCAGATCAAGGAATATCTGGGCCTGAGCGTAGGGCAGACGATCAAGACCTGGTCGGTCAT
CGAAACCCTGATCGCCGTCCTGGGGCTGGTGTTCTGCCTGCTGCTGTCGCTGGTGATCCACTGA

Upstream 100 bases:

>100_bases
GTGAACTCTTCGTCCTCTCCGGGATATGAGGCCGCGGGCATTGACATCCTGCGGCCCGTGACGCCGTGATACGCGCTCTT
TTTCCAGCAGACGTGGTTCC

Downstream 100 bases:

>100_bases
GGGGGCGCCTGCCCCCTCGTACCCCTGCCTGTTACCCCTGCCCTTCGGCGTAGGGGTTCTTGGTCCCGCGCAGCAGCAGC
CGGATCGGCGTGCCGGGCAG

Product: gluconate permease

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSSLLAVSLATAAIVAVVLLIGRYKLNPFIVLLCVSLLLALCAGMPPQKAVTSFEAGAGHVLGHIATVIALGTMLGKMLA
ESGGADQIALTITRVAGKGRISWAMMVIGLLIGLPVFFEVGFVLLIPLVFTLARRTSTPMLLLALPMGAALSVTHAMIPP
HPATLLALSAYHADTGRTIFWGVIIGTPIAALAGPIYAKFITPRIQIAGHAGLEDQFASKDVHENLPPFSITVLTILSPV
LLMLLGSVADLVSQPGSTANTILHFIGNTDIALLLATILSFYVLGLARGFSRETILRFTNECLGPTALIMLLVGAGGGFG
RELVDSGVSKAITDLALGAHVPLLVLAWLLAVVVRVAAGSATVAMSTASGIVGPILLHSHGTSPELMVLVTGAGSVALGP
MNDAGFWQIKEYLGLSVGQTIKTWSVIETLIAVLGLVFCLLLSLVIH

Sequences:

>Translated_447_residues
MSSLLAVSLATAAIVAVVLLIGRYKLNPFIVLLCVSLLLALCAGMPPQKAVTSFEAGAGHVLGHIATVIALGTMLGKMLA
ESGGADQIALTITRVAGKGRISWAMMVIGLLIGLPVFFEVGFVLLIPLVFTLARRTSTPMLLLALPMGAALSVTHAMIPP
HPATLLALSAYHADTGRTIFWGVIIGTPIAALAGPIYAKFITPRIQIAGHAGLEDQFASKDVHENLPPFSITVLTILSPV
LLMLLGSVADLVSQPGSTANTILHFIGNTDIALLLATILSFYVLGLARGFSRETILRFTNECLGPTALIMLLVGAGGGFG
RELVDSGVSKAITDLALGAHVPLLVLAWLLAVVVRVAAGSATVAMSTASGIVGPILLHSHGTSPELMVLVTGAGSVALGP
MNDAGFWQIKEYLGLSVGQTIKTWSVIETLIAVLGLVFCLLLSLVIH
>Mature_446_residues
SSLLAVSLATAAIVAVVLLIGRYKLNPFIVLLCVSLLLALCAGMPPQKAVTSFEAGAGHVLGHIATVIALGTMLGKMLAE
SGGADQIALTITRVAGKGRISWAMMVIGLLIGLPVFFEVGFVLLIPLVFTLARRTSTPMLLLALPMGAALSVTHAMIPPH
PATLLALSAYHADTGRTIFWGVIIGTPIAALAGPIYAKFITPRIQIAGHAGLEDQFASKDVHENLPPFSITVLTILSPVL
LMLLGSVADLVSQPGSTANTILHFIGNTDIALLLATILSFYVLGLARGFSRETILRFTNECLGPTALIMLLVGAGGGFGR
ELVDSGVSKAITDLALGAHVPLLVLAWLLAVVVRVAAGSATVAMSTASGIVGPILLHSHGTSPELMVLVTGAGSVALGPM
NDAGFWQIKEYLGLSVGQTIKTWSVIETLIAVLGLVFCLLLSLVIH

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=433, Percent_Identity=42.2632794457275, Blast_Score=324, Evalue=8e-90,
Organism=Escherichia coli, GI1790716, Length=430, Percent_Identity=39.0697674418605, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1788707, Length=447, Percent_Identity=36.0178970917226, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI2367370, Length=428, Percent_Identity=36.4485981308411, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1790776, Length=434, Percent_Identity=32.9493087557604, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI48994939, Length=440, Percent_Identity=33.6363636363636, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789097, Length=453, Percent_Identity=34.878587196468, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46368; Mature: 46237

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLAVSLATAAIVAVVLLIGRYKLNPFIVLLCVSLLLALCAGMPPQKAVTSFEAGAGH
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHH
VLGHIATVIALGTMLGKMLAESGGADQIALTITRVAGKGRISWAMMVIGLLIGLPVFFEV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GFVLLIPLVFTLARRTSTPMLLLALPMGAALSVTHAMIPPHPATLLALSAYHADTGRTIF
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEE
WGVIIGTPIAALAGPIYAKFITPRIQIAGHAGLEDQFASKDVHENLPPFSITVLTILSPV
EHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCHHHHCCCCHHHHHHHHHHHH
LLMLLGSVADLVSQPGSTANTILHFIGNTDIALLLATILSFYVLGLARGFSRETILRFTN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ECLGPTALIMLLVGAGGGFGRELVDSGVSKAITDLALGAHVPLLVLAWLLAVVVRVAAGS
HHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATVAMSTASGIVGPILLHSHGTSPELMVLVTGAGSVALGPMNDAGFWQIKEYLGLSVGQT
CEEEEEHHCCCHHHHHEECCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHCCHHCCH
IKTWSVIETLIAVLGLVFCLLLSLVIH
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLLAVSLATAAIVAVVLLIGRYKLNPFIVLLCVSLLLALCAGMPPQKAVTSFEAGAGH
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHH
VLGHIATVIALGTMLGKMLAESGGADQIALTITRVAGKGRISWAMMVIGLLIGLPVFFEV
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
GFVLLIPLVFTLARRTSTPMLLLALPMGAALSVTHAMIPPHPATLLALSAYHADTGRTIF
HHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEE
WGVIIGTPIAALAGPIYAKFITPRIQIAGHAGLEDQFASKDVHENLPPFSITVLTILSPV
EHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHCCHHHHCCCCHHHHHHHHHHHH
LLMLLGSVADLVSQPGSTANTILHFIGNTDIALLLATILSFYVLGLARGFSRETILRFTN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ECLGPTALIMLLVGAGGGFGRELVDSGVSKAITDLALGAHVPLLVLAWLLAVVVRVAAGS
HHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATVAMSTASGIVGPILLHSHGTSPELMVLVTGAGSVALGPMNDAGFWQIKEYLGLSVGQT
CEEEEEHHCCCHHHHHEECCCCCCCEEEEEECCCCEEECCCCCCHHHHHHHHHCCHHCCH
IKTWSVIETLIAVLGLVFCLLLSLVIH
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA