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The map label for this gene is yhcK [H]

Identifier: 162148938

GI number: 162148938

Start: 3256356

End: 3257768

Strand: Reverse

Name: yhcK [H]

Synonym: GDI_3168

Alternate gene names: 162148938

Gene position: 3257768-3256356 (Counterclockwise)

Preceding gene: 162148940

Following gene: 162148932

Centisome position: 82.6

GC content: 63.2

Gene sequence:

>1413_bases
GTGGTGACGCGTTTCCTGTGCTCCGACGACGAGGGTTATACGTCGTTCTGGCCGCCCAACGCCGTGATGCTCGCGGCATT
GCTTACGCTTCGCATGCGTCTCGCGGCATGCGTTCTCGTCGCGTGCTTCCTGCTTAACCTGCTGGTCAACCGACAGAGCG
CCCTTTCTCCGCCCGAATCCCTGCTGGCCTGCGTCCTCAACGTTTTCCTGGTCGTGTTGGCCGCGCCCTTCACCCGGCGA
TTCTGCGGGGCCATGACGAACCTGACGCGCCCACGGCGTTTCGTGGCCTTCACGATCATCGCCGTGCTGGCGGCGGCCGT
CGAGGCCGGGGCAGGGACGACCTTCGAACGCGTCGTGCTGGACGACCCCAGCGAGCAGCTCGGGGAATGGCTGCAATGGG
TCTTCTGCGACGCTTTGGGGCTTCTGCTTGCCACCCCGGCGATGCTGTCCGTCTTGCGGTACTGGGAAGGACGGAAGCCC
CACCGGAATGGTCCGGCCGGGCCCGTCATCCTGTCGGTCGTTTCGGTCGTCCTGGCGATCTTTCTGTTTTCGTTCTCGCG
ATCGTCCTTTTTCCTGTTTACCTACCCCGTTCTTGTGCTGCTGGCTTTCCGCGCCTCGGCCGGACAGGTGCTCACGTCGA
TCTTCTTCGTCTCGGTTTTCACCTCGGCACTGACCGCCCACGGGCTGGGACCGATCGCACGCCTCTCGCCCGACGGGCAT
CTGATGCGCGCGGCGATGCTCCAGCCCTATCTTTTCTCGCTCTTCCTGACGGCGGTCCTCGTCAGCAACGCCAGCGGGGA
AAATCGCCGGCATACGAACCGCCTTTCCCTCATGAAGCAGCATCTGGAATATGCGGCCACGCATGATTCCCTGACATCCC
TGATCAACCGGCGACGTTTGAGACATATTCTTGTCTCTCTGCTCGTCGAGGGCTCTCCGGGGGCCGTGTTCCTGATCGAC
ATCGACCATTTCAAGCAGATCAACGACAGCCTGGGCCACCATATCGGGGACGAGGTCCTGAAGGCGTTCAGCAAACGCAT
GGTCGATCTTCTCGCGTGCCGCAACGCGCATATCGCGCGCCTGGGCGGCGATGAATTCGCAGCCATCGTGCCCGGACACT
TCACGCACGAGATGCTCGATGTCCTGTGCTCGTCGTTCGCCGACGGCCTGCTTCTGCAGCCCTATATCCTGTCGTGCGGC
GAACGGTCCGTGACCGCCAGCATCGGCGCGGCGTTCTTTCATGCGACGGACGCGCATCTGCAGCCGGGCGAGATCATCCG
CCGCGCGGATGTCGCGCTCTATCAGGCAAAACGGGCCGGTCGAAACGGCTATTGTCTTTTTTCAGCTGCTTCCGGTCCGC
CGTCGCATGGACAGGCGGACCCGGCGGACCATCACGCCACGACCGGTCCCTGA

Upstream 100 bases:

>100_bases
CGGAGGGGTTTGCATGCGTTGGCGGCCCTGTAGACGAGCCGAGCCCAATCGAAGCATCAGGCACGCAATCGTCCTGGTAC
TGATTTTTGGCGCCATTACC

Downstream 100 bases:

>100_bases
CGGCGCGGGGCGCAGGTCCGGCCTATGCCGCCTGCGGGGCCGCGTCGCGGTCGTGCAGCAGTTCGCCGGCCACGTAGGTT
GCGCGGACGCTGCGGTCGTC

Product: GGDEF family signaling protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MVTRFLCSDDEGYTSFWPPNAVMLAALLTLRMRLAACVLVACFLLNLLVNRQSALSPPESLLACVLNVFLVVLAAPFTRR
FCGAMTNLTRPRRFVAFTIIAVLAAAVEAGAGTTFERVVLDDPSEQLGEWLQWVFCDALGLLLATPAMLSVLRYWEGRKP
HRNGPAGPVILSVVSVVLAIFLFSFSRSSFFLFTYPVLVLLAFRASAGQVLTSIFFVSVFTSALTAHGLGPIARLSPDGH
LMRAAMLQPYLFSLFLTAVLVSNASGENRRHTNRLSLMKQHLEYAATHDSLTSLINRRRLRHILVSLLVEGSPGAVFLID
IDHFKQINDSLGHHIGDEVLKAFSKRMVDLLACRNAHIARLGGDEFAAIVPGHFTHEMLDVLCSSFADGLLLQPYILSCG
ERSVTASIGAAFFHATDAHLQPGEIIRRADVALYQAKRAGRNGYCLFSAASGPPSHGQADPADHHATTGP

Sequences:

>Translated_470_residues
MVTRFLCSDDEGYTSFWPPNAVMLAALLTLRMRLAACVLVACFLLNLLVNRQSALSPPESLLACVLNVFLVVLAAPFTRR
FCGAMTNLTRPRRFVAFTIIAVLAAAVEAGAGTTFERVVLDDPSEQLGEWLQWVFCDALGLLLATPAMLSVLRYWEGRKP
HRNGPAGPVILSVVSVVLAIFLFSFSRSSFFLFTYPVLVLLAFRASAGQVLTSIFFVSVFTSALTAHGLGPIARLSPDGH
LMRAAMLQPYLFSLFLTAVLVSNASGENRRHTNRLSLMKQHLEYAATHDSLTSLINRRRLRHILVSLLVEGSPGAVFLID
IDHFKQINDSLGHHIGDEVLKAFSKRMVDLLACRNAHIARLGGDEFAAIVPGHFTHEMLDVLCSSFADGLLLQPYILSCG
ERSVTASIGAAFFHATDAHLQPGEIIRRADVALYQAKRAGRNGYCLFSAASGPPSHGQADPADHHATTGP
>Mature_470_residues
MVTRFLCSDDEGYTSFWPPNAVMLAALLTLRMRLAACVLVACFLLNLLVNRQSALSPPESLLACVLNVFLVVLAAPFTRR
FCGAMTNLTRPRRFVAFTIIAVLAAAVEAGAGTTFERVVLDDPSEQLGEWLQWVFCDALGLLLATPAMLSVLRYWEGRKP
HRNGPAGPVILSVVSVVLAIFLFSFSRSSFFLFTYPVLVLLAFRASAGQVLTSIFFVSVFTSALTAHGLGPIARLSPDGH
LMRAAMLQPYLFSLFLTAVLVSNASGENRRHTNRLSLMKQHLEYAATHDSLTSLINRRRLRHILVSLLVEGSPGAVFLID
IDHFKQINDSLGHHIGDEVLKAFSKRMVDLLACRNAHIARLGGDEFAAIVPGHFTHEMLDVLCSSFADGLLLQPYILSCG
ERSVTASIGAAFFHATDAHLQPGEIIRRADVALYQAKRAGRNGYCLFSAASGPPSHGQADPADHHATTGP

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=173, Percent_Identity=31.7919075144509, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI145693134, Length=187, Percent_Identity=34.2245989304813, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=34.6820809248555, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788381, Length=195, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=35.8823529411765, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787541, Length=188, Percent_Identity=30.8510638297872, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=34.5029239766082, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=34.9112426035503, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082007, Length=197, Percent_Identity=30.9644670050761, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787056, Length=157, Percent_Identity=31.8471337579618, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 51196; Mature: 51196

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRFLCSDDEGYTSFWPPNAVMLAALLTLRMRLAACVLVACFLLNLLVNRQSALSPPES
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHH
LLACVLNVFLVVLAAPFTRRFCGAMTNLTRPRRFVAFTIIAVLAAAVEAGAGTTFERVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
DDPSEQLGEWLQWVFCDALGLLLATPAMLSVLRYWEGRKPHRNGPAGPVILSVVSVVLAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
FLFSFSRSSFFLFTYPVLVLLAFRASAGQVLTSIFFVSVFTSALTAHGLGPIARLSPDGH
HHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHH
LMRAAMLQPYLFSLFLTAVLVSNASGENRRHTNRLSLMKQHLEYAATHDSLTSLINRRRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHILVSLLVEGSPGAVFLIDIDHFKQINDSLGHHIGDEVLKAFSKRMVDLLACRNAHIAR
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LGGDEFAAIVPGHFTHEMLDVLCSSFADGLLLQPYILSCGERSVTASIGAAFFHATDAHL
ECCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
QPGEIIRRADVALYQAKRAGRNGYCLFSAASGPPSHGQADPADHHATTGP
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVTRFLCSDDEGYTSFWPPNAVMLAALLTLRMRLAACVLVACFLLNLLVNRQSALSPPES
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHH
LLACVLNVFLVVLAAPFTRRFCGAMTNLTRPRRFVAFTIIAVLAAAVEAGAGTTFERVVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
DDPSEQLGEWLQWVFCDALGLLLATPAMLSVLRYWEGRKPHRNGPAGPVILSVVSVVLAI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
FLFSFSRSSFFLFTYPVLVLLAFRASAGQVLTSIFFVSVFTSALTAHGLGPIARLSPDGH
HHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHH
LMRAAMLQPYLFSLFLTAVLVSNASGENRRHTNRLSLMKQHLEYAATHDSLTSLINRRRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHILVSLLVEGSPGAVFLIDIDHFKQINDSLGHHIGDEVLKAFSKRMVDLLACRNAHIAR
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LGGDEFAAIVPGHFTHEMLDVLCSSFADGLLLQPYILSCGERSVTASIGAAFFHATDAHL
ECCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
QPGEIIRRADVALYQAKRAGRNGYCLFSAASGPPSHGQADPADHHATTGP
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]