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The map label for this gene is asnC [H]

Identifier: 162148924

GI number: 162148924

Start: 3244341

End: 3244853

Strand: Reverse

Name: asnC [H]

Synonym: GDI_3154

Alternate gene names: 162148924

Gene position: 3244853-3244341 (Counterclockwise)

Preceding gene: 162148928

Following gene: 162148923

Centisome position: 82.27

GC content: 69.4

Gene sequence:

>513_bases
ATGACTGAAGTGATGGACCTGGATGCGATTGACCGTCGGATCGTAGCCGAACTCCAGGCGGATGGCCGCATGACGAACGT
GGAACTGGCGCGCCGGGTCGGTATTTCCGCCCCGCCCTGCCTGCGGCGCGTGCGGCGGCTGGAGGAAGAAGGGCTGATCC
GCGGCTACCACGCCGATACCGACGCCGCCCTGCTGGGCTGGACGATCACGCTGTTCGCCCTGATCGGGCTGGACAGCCAG
AAGGAAGCCGTCCTGACCGCGTTCGAGACCCAGGTGGCCGAATGGCCCGAGGTCCGGGAGTGCCACATGATCCGGGGCGG
CGGGGACTTCCTGGTCCGGCTGGTGGCGCGCGACGCCGCGCATGAAAACCAGTTGACCCGCCGCCTGACCGAAAGCCCGC
ATGTCAGCCGGGTCCAGACATTGCAGACCATCCGCACGGCGCTGAGCCGCGCCGGCGTGCCCGTGCAGCCCCCCGGCGCC
GGCGGCATGGGCGTGGCAGGGACGGACATGTGA

Upstream 100 bases:

>100_bases
GCCGTCCAATGCGCTGGACACAAGGCGCGCGGGATCTGCTGCGCCCTTTTCGGCAACGGGCGCATGCCATATCCTGCGCG
CCATCAGATTTGGGACGGAA

Downstream 100 bases:

>100_bases
GCATCGTCCTGCCCCCCGTCGATGCACCGCCGGCCACCAAGGCGCGGCCCGACACGGTCCGGCTGGCGGCCGATATCAGC
ATCGTGGTCCCCTGCTACAA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MTEVMDLDAIDRRIVAELQADGRMTNVELARRVGISAPPCLRRVRRLEEEGLIRGYHADTDAALLGWTITLFALIGLDSQ
KEAVLTAFETQVAEWPEVRECHMIRGGGDFLVRLVARDAAHENQLTRRLTESPHVSRVQTLQTIRTALSRAGVPVQPPGA
GGMGVAGTDM

Sequences:

>Translated_170_residues
MTEVMDLDAIDRRIVAELQADGRMTNVELARRVGISAPPCLRRVRRLEEEGLIRGYHADTDAALLGWTITLFALIGLDSQ
KEAVLTAFETQVAEWPEVRECHMIRGGGDFLVRLVARDAAHENQLTRRLTESPHVSRVQTLQTIRTALSRAGVPVQPPGA
GGMGVAGTDM
>Mature_169_residues
TEVMDLDAIDRRIVAELQADGRMTNVELARRVGISAPPCLRRVRRLEEEGLIRGYHADTDAALLGWTITLFALIGLDSQK
EAVLTAFETQVAEWPEVRECHMIRGGGDFLVRLVARDAAHENQLTRRLTESPHVSRVQTLQTIRTALSRAGVPVQPPGAG
GMGVAGTDM

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=136, Percent_Identity=41.9117647058824, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=30.4635761589404, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18653; Mature: 18521

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVMDLDAIDRRIVAELQADGRMTNVELARRVGISAPPCLRRVRRLEEEGLIRGYHADT
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCCC
DAALLGWTITLFALIGLDSQKEAVLTAFETQVAEWPEVRECHMIRGGGDFLVRLVARDAA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHEEECCHHHHHHHHHHHHH
HENQLTRRLTESPHVSRVQTLQTIRTALSRAGVPVQPPGAGGMGVAGTDM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEVMDLDAIDRRIVAELQADGRMTNVELARRVGISAPPCLRRVRRLEEEGLIRGYHADT
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEECCCCCC
DAALLGWTITLFALIGLDSQKEAVLTAFETQVAEWPEVRECHMIRGGGDFLVRLVARDAA
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHEEECCHHHHHHHHHHHHH
HENQLTRRLTESPHVSRVQTLQTIRTALSRAGVPVQPPGAGGMGVAGTDM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]