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The map label for this gene is pgm [H]

Identifier: 162148907

GI number: 162148907

Start: 3226167

End: 3227828

Strand: Direct

Name: pgm [H]

Synonym: GDI_3137

Alternate gene names: 162148907

Gene position: 3226167-3227828 (Clockwise)

Preceding gene: 162148906

Following gene: 162148910

Centisome position: 81.8

GC content: 68.11

Gene sequence:

>1662_bases
ATGGCCACCATCAGCCCACTGGCGGGCAAGCCCGTTGCGCCGTCACGCCTGATCGACGTCGCGAAGCTGACTACCGCCTA
TTACGACCTGAAGCCCGATCCCCGGATCACGGCCCAGCGGGTTACCTTCGGAACGTCGGGCCATCGTGGCTCGCCGCTCC
AGACCGGCTTCAACGAGGCCCATATCCTGGCGATCAGCCAGGCGGTCTGCGATTACCGCGCGGCGGCGGGCATCGACGGG
CCGCTCTATATCGGCATCGACACCCATGCGGTCTCGAAGCCGGCCCTGGCCTCGGCGCTGGAAGTGTTCGCGGCCAACGG
GGTGGACGTCTTCATCGACGCCCAGGACGGCTACACCCCCACGCCGGTGATTTCGCACGCCATCCTGACCTACAACAAGG
GACGCACCAGCGGCCTGGCGGATGGCGTCGTCCTGACGCCCTCGCACAACCCGCCGGAAGATGGCGGCTATAAATACAAC
CCGCCCCATGGCGGACCGGCGGACACGGGCATCACCCGCACCATCGAACGCGCGGCCAACGACTTCCTCGCCTCCGGCCT
GGCGGGGGTGCGGCGCATTCCGTACGAACAGGCACTGCGCGCCGCCTGCGTGCATCGGCACGATTACATCACGCCCTACG
TCGCGGACCTCGGTTCGGTCCTCGACATGGCGGCGATCCGCGCCTCGGGGGTCAAGATCGGCATCGATCCGCTGGGGGGG
GCCGCCGTCGCCTACTGGCAGCCGATCATCGAACGGTACGGCATCGACGCCACCGTGGTCAGCGACGTCGTGGACCCGAC
CTTCTCGTTCATGACGGCCGACTGGGACGGGCAGATCCGCATGGACTGTTCCTCGCCCTACGCGATGGGCCGGCTGATCG
AGGCCGGACGGACGTTCGACGTGGCTTTCGCCAACGATACCGATGCCGACCGGCACGGCATCGTCGCGGGCAGCGACGGG
CTGATGAACCCGAACCATTACCTCGCCACCGCCATCGCCTACCTGTTCGCCAACCGGCCGGGCTGGAGCCCCCAGGCGGC
GGTGGGCAAGACGGTGGTCAGCAGCAGCATGATCGACCGGGTGGCGGGCAAGCTCGGGCGCCGTCTGGTCGAGGTGCCGG
TCGGCTTCAAATGGTTCGTCGACGGGCTGATCGACGGCTCGTTCGGCTTCGCGGGCGAGGAAAGCGCCGGCGCCTCGTTC
CTGCGCACGGACGGCACCGCCTGGACGACGGACAAGGACGGCATCATCCTGGGACTGCTGGCCGCCGAAATGACGGCGCG
CACCGGGCACAATCCCGGCGTGGCCTATCGCGACCTGACGGCCGAACTGGGCACGCCCTATTATGCCCGGATCGACGCGC
CCGCCACAGCCGAGCAGAAATCGCTGCTGAAGTCGCTGTCGGCGGAACAGGTCGGCCTGCAGGACCTGGCGGGCGAGCCC
ATCCGGGCGACGCTGACCCGCGCCCCCGGCAATGACGCGGACATCGGCGGCCTGAAGATCGTCACGGACAATGGCTGGTT
CGCCGCCCGCCCCTCGGGCACCGAGGACGTCTACAAGATCTATGCCGAGAGCTTCGTCAGCGAGGACCATCTGCACCGCA
TCCAGCACGAGGCGGCGGACGCCATCTCGTCCCTGTTCGCGACCCAGGAAGGTTCAGGCTGA

Upstream 100 bases:

>100_bases
ACCACCGTGACCGAAGGGGCGGGTCAGACCGCCGGCACGGCGCCGCCCGCCCACCCCTGAACTGGCACCGCGAACCGCTA
CTACCGGGAAGGAACACAGG

Downstream 100 bases:

>100_bases
CAGCACGAGGAAGGCCCGAGGGGTCGTGGACCCTTCGGGCCTGGAGCGCCTTGCGGTTGCGTGACGCCATCCGATCACGA
TCTGCCCTACTGGAAGTCTG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MATISPLAGKPVAPSRLIDVAKLTTAYYDLKPDPRITAQRVTFGTSGHRGSPLQTGFNEAHILAISQAVCDYRAAAGIDG
PLYIGIDTHAVSKPALASALEVFAANGVDVFIDAQDGYTPTPVISHAILTYNKGRTSGLADGVVLTPSHNPPEDGGYKYN
PPHGGPADTGITRTIERAANDFLASGLAGVRRIPYEQALRAACVHRHDYITPYVADLGSVLDMAAIRASGVKIGIDPLGG
AAVAYWQPIIERYGIDATVVSDVVDPTFSFMTADWDGQIRMDCSSPYAMGRLIEAGRTFDVAFANDTDADRHGIVAGSDG
LMNPNHYLATAIAYLFANRPGWSPQAAVGKTVVSSSMIDRVAGKLGRRLVEVPVGFKWFVDGLIDGSFGFAGEESAGASF
LRTDGTAWTTDKDGIILGLLAAEMTARTGHNPGVAYRDLTAELGTPYYARIDAPATAEQKSLLKSLSAEQVGLQDLAGEP
IRATLTRAPGNDADIGGLKIVTDNGWFAARPSGTEDVYKIYAESFVSEDHLHRIQHEAADAISSLFATQEGSG

Sequences:

>Translated_553_residues
MATISPLAGKPVAPSRLIDVAKLTTAYYDLKPDPRITAQRVTFGTSGHRGSPLQTGFNEAHILAISQAVCDYRAAAGIDG
PLYIGIDTHAVSKPALASALEVFAANGVDVFIDAQDGYTPTPVISHAILTYNKGRTSGLADGVVLTPSHNPPEDGGYKYN
PPHGGPADTGITRTIERAANDFLASGLAGVRRIPYEQALRAACVHRHDYITPYVADLGSVLDMAAIRASGVKIGIDPLGG
AAVAYWQPIIERYGIDATVVSDVVDPTFSFMTADWDGQIRMDCSSPYAMGRLIEAGRTFDVAFANDTDADRHGIVAGSDG
LMNPNHYLATAIAYLFANRPGWSPQAAVGKTVVSSSMIDRVAGKLGRRLVEVPVGFKWFVDGLIDGSFGFAGEESAGASF
LRTDGTAWTTDKDGIILGLLAAEMTARTGHNPGVAYRDLTAELGTPYYARIDAPATAEQKSLLKSLSAEQVGLQDLAGEP
IRATLTRAPGNDADIGGLKIVTDNGWFAARPSGTEDVYKIYAESFVSEDHLHRIQHEAADAISSLFATQEGSG
>Mature_552_residues
ATISPLAGKPVAPSRLIDVAKLTTAYYDLKPDPRITAQRVTFGTSGHRGSPLQTGFNEAHILAISQAVCDYRAAAGIDGP
LYIGIDTHAVSKPALASALEVFAANGVDVFIDAQDGYTPTPVISHAILTYNKGRTSGLADGVVLTPSHNPPEDGGYKYNP
PHGGPADTGITRTIERAANDFLASGLAGVRRIPYEQALRAACVHRHDYITPYVADLGSVLDMAAIRASGVKIGIDPLGGA
AVAYWQPIIERYGIDATVVSDVVDPTFSFMTADWDGQIRMDCSSPYAMGRLIEAGRTFDVAFANDTDADRHGIVAGSDGL
MNPNHYLATAIAYLFANRPGWSPQAAVGKTVVSSSMIDRVAGKLGRRLVEVPVGFKWFVDGLIDGSFGFAGEESAGASFL
RTDGTAWTTDKDGIILGLLAAEMTARTGHNPGVAYRDLTAELGTPYYARIDAPATAEQKSLLKSLSAEQVGLQDLAGEPI
RATLTRAPGNDADIGGLKIVTDNGWFAARPSGTEDVYKIYAESFVSEDHLHRIQHEAADAISSLFATQEGSG

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=473, Percent_Identity=26.0042283298097, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI21361621, Length=472, Percent_Identity=26.6949152542373, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI133922562, Length=394, Percent_Identity=27.1573604060914, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI1786904, Length=539, Percent_Identity=59.3692022263451, Blast_Score=641, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=404, Percent_Identity=26.4851485148515, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322722, Length=548, Percent_Identity=28.2846715328467, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323752, Length=541, Percent_Identity=25.8780036968577, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864244, Length=440, Percent_Identity=27.5, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58512; Mature: 58381

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATISPLAGKPVAPSRLIDVAKLTTAYYDLKPDPRITAQRVTFGTSGHRGSPLQTGFNEA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCE
HILAISQAVCDYRAAAGIDGPLYIGIDTHAVSKPALASALEVFAANGVDVFIDAQDGYTP
EEEEHHHHHHHHHHHCCCCCCEEEEECHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
TPVISHAILTYNKGRTSGLADGVVLTPSHNPPEDGGYKYNPPHGGPADTGITRTIERAAN
CHHHHHHHEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
DFLASGLAGVRRIPYEQALRAACVHRHDYITPYVADLGSVLDMAAIRASGVKIGIDPLGG
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCC
AAVAYWQPIIERYGIDATVVSDVVDPTFSFMTADWDGQIRMDCSSPYAMGRLIEAGRTFD
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHEEEECCCCEEEEECCCCHHHHHHHHCCCEEE
VAFANDTDADRHGIVAGSDGLMNPNHYLATAIAYLFANRPGWSPQAAVGKTVVSSSMIDR
EEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VAGKLGRRLVEVPVGFKWFVDGLIDGSFGFAGEESAGASFLRTDGTAWTTDKDGIILGLL
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEECCCCCEEEEHH
AAEMTARTGHNPGVAYRDLTAELGTPYYARIDAPATAEQKSLLKSLSAEQVGLQDLAGEP
HHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCC
IRATLTRAPGNDADIGGLKIVTDNGWFAARPSGTEDVYKIYAESFVSEDHLHRIQHEAAD
CEEEEEECCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
AISSLFATQEGSG
HHHHHHHHCCCCC
>Mature Secondary Structure 
ATISPLAGKPVAPSRLIDVAKLTTAYYDLKPDPRITAQRVTFGTSGHRGSPLQTGFNEA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCE
HILAISQAVCDYRAAAGIDGPLYIGIDTHAVSKPALASALEVFAANGVDVFIDAQDGYTP
EEEEHHHHHHHHHHHCCCCCCEEEEECHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCC
TPVISHAILTYNKGRTSGLADGVVLTPSHNPPEDGGYKYNPPHGGPADTGITRTIERAAN
CHHHHHHHEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHH
DFLASGLAGVRRIPYEQALRAACVHRHDYITPYVADLGSVLDMAAIRASGVKIGIDPLGG
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCC
AAVAYWQPIIERYGIDATVVSDVVDPTFSFMTADWDGQIRMDCSSPYAMGRLIEAGRTFD
HHHHHHHHHHHHHCCCHHHHHHHHCCCHHEEEECCCCEEEEECCCCHHHHHHHHCCCEEE
VAFANDTDADRHGIVAGSDGLMNPNHYLATAIAYLFANRPGWSPQAAVGKTVVSSSMIDR
EEECCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VAGKLGRRLVEVPVGFKWFVDGLIDGSFGFAGEESAGASFLRTDGTAWTTDKDGIILGLL
HHHHHHHEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCEEECCCCCEEEEHH
AAEMTARTGHNPGVAYRDLTAELGTPYYARIDAPATAEQKSLLKSLSAEQVGLQDLAGEP
HHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCCC
IRATLTRAPGNDADIGGLKIVTDNGWFAARPSGTEDVYKIYAESFVSEDHLHRIQHEAAD
CEEEEEECCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHH
AISSLFATQEGSG
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]