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The map label for this gene is aatA [H]

Identifier: 162148895

GI number: 162148895

Start: 3215446

End: 3216690

Strand: Reverse

Name: aatA [H]

Synonym: GDI_3125

Alternate gene names: 162148895

Gene position: 3216690-3215446 (Counterclockwise)

Preceding gene: 162148896

Following gene: 162148894

Centisome position: 81.56

GC content: 70.36

Gene sequence:

>1245_bases
CTGAACGTGACGGGCACGGGTCCGGCGGGCGTCGGGGTGGCCGAACCGGGCTTTGCCGCGCGCACCGCGCGCCTGGACTC
GCCCGCCACCATCGCCATGGCGGTCCGGGCCCGCGCCCTGCGGGCCGAAGGGCACCAGGTCCTGTCCCTGGCGCTGGGCG
AGCCCGATTTCGCGACGCCGCACGCGGTGATCGAGGCCGCCCATCGCGCCGCGCTGGACGGGCAGACGAAATACCCGCCC
GTCGACGGCACGCCGGCGCTGAAGGCGGCGATCGCACGGAAGTTCGAGCGCGAGAATGGCCTGGCCTACACGCCTGCGGA
ACTGATGGTGTCCAACGGCGGCAAGCAGGTGATCTTCAACGCCTTCATGGCGACGATCGATGCGGGGGACGAAATCGTCA
TTCCCTCGCCCTACTGGGTCAGCTACCCGCTGGCGGCGCGGCTGTTCGGCGGCGTGCCGGTCTTCGCCGCATGCCGCGAG
GAAGACGGATTCCGCCTGACCGCCCCGGCGCTGGAGGCCGCGCTGTCGCCGCGCACGCGCTGGGTGGTGCTGAATTTTCC
CAACAACCCGACCGGCGCGGTGGTCACGCTCGCGGACCTGGAAGCGATCTCCGAGGTACTGCGCCGCTATCCGCAGGCCT
GGATCCTGTCCGACGAAATCTACGAACATCTGGTCTTCGACGGGGCGCGGCACCATTCCCTCGCCGCCGTGGCGCCCGAC
CTGAAATCCCGCATCCTGACGCTGAACGGCGTGTCGAAATCCTATGCCATGACCGGCTGGCGCATCGGCTATGGCGGCGG
CCCGGCGCGGCTGATCCGCATGATGACGCGGGTGCAGGGGAATGCGACCTCCGGCGTGTGTTCCATCGCCCAGGCCGCCG
CCGCGGCCGCCCTGGACGGACCGGCCGGGCTGGTGGCCGAAATGCGCGACACCTATGCCCGGCGCCGCGCCATGGTGGTC
GAGTCCCTGCGCGCCATCCCCGGGGTGACATGCGCCATGCCGCAGGGCGCGTTCTATGCCTATCCGGGGATTGCCGGATG
CCTGGGCAAGACCAGCCAGGGCGGCCGCATGCTGCGAACGGACGAGGATTTCGCCATCGCCCTGCTGGATGAACAGCACG
TGGCCTGCGTCCAAGGCAGCGCCTTCGGCAAGGGACCCTATCTGCGCCTGTCCTGCGCCACGGATGACGAGACGCTGCGC
GAAGCCTGCGCGCGCATCGCGACGTTCGTCGCCGGCCTGGGCTGA

Upstream 100 bases:

>100_bases
CCTTCATGTTCGCCGGCCATTTCCGCATTTCCTACGCGACCGATACCGAAAGCCTGCGCGAAGCCTGCACCCGCATCCAG
CGCTTCTGCGCCGGGTTGCG

Downstream 100 bases:

>100_bases
GGAACCGCACGCCGGCTCTATTCCCCGTCGAACGGCCAGTCCATGCGGGTCAGTTGCCGGGGGGCCACTTGCGAGACTGC
CATCCCGGCCACGAAGATCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNVTGTGPAGVGVAEPGFAARTARLDSPATIAMAVRARALRAEGHQVLSLALGEPDFATPHAVIEAAHRAALDGQTKYPP
VDGTPALKAAIARKFERENGLAYTPAELMVSNGGKQVIFNAFMATIDAGDEIVIPSPYWVSYPLAARLFGGVPVFAACRE
EDGFRLTAPALEAALSPRTRWVVLNFPNNPTGAVVTLADLEAISEVLRRYPQAWILSDEIYEHLVFDGARHHSLAAVAPD
LKSRILTLNGVSKSYAMTGWRIGYGGGPARLIRMMTRVQGNATSGVCSIAQAAAAAALDGPAGLVAEMRDTYARRRAMVV
ESLRAIPGVTCAMPQGAFYAYPGIAGCLGKTSQGGRMLRTDEDFAIALLDEQHVACVQGSAFGKGPYLRLSCATDDETLR
EACARIATFVAGLG

Sequences:

>Translated_414_residues
MNVTGTGPAGVGVAEPGFAARTARLDSPATIAMAVRARALRAEGHQVLSLALGEPDFATPHAVIEAAHRAALDGQTKYPP
VDGTPALKAAIARKFERENGLAYTPAELMVSNGGKQVIFNAFMATIDAGDEIVIPSPYWVSYPLAARLFGGVPVFAACRE
EDGFRLTAPALEAALSPRTRWVVLNFPNNPTGAVVTLADLEAISEVLRRYPQAWILSDEIYEHLVFDGARHHSLAAVAPD
LKSRILTLNGVSKSYAMTGWRIGYGGGPARLIRMMTRVQGNATSGVCSIAQAAAAAALDGPAGLVAEMRDTYARRRAMVV
ESLRAIPGVTCAMPQGAFYAYPGIAGCLGKTSQGGRMLRTDEDFAIALLDEQHVACVQGSAFGKGPYLRLSCATDDETLR
EACARIATFVAGLG
>Mature_414_residues
MNVTGTGPAGVGVAEPGFAARTARLDSPATIAMAVRARALRAEGHQVLSLALGEPDFATPHAVIEAAHRAALDGQTKYPP
VDGTPALKAAIARKFERENGLAYTPAELMVSNGGKQVIFNAFMATIDAGDEIVIPSPYWVSYPLAARLFGGVPVFAACRE
EDGFRLTAPALEAALSPRTRWVVLNFPNNPTGAVVTLADLEAISEVLRRYPQAWILSDEIYEHLVFDGARHHSLAAVAPD
LKSRILTLNGVSKSYAMTGWRIGYGGGPARLIRMMTRVQGNATSGVCSIAQAAAAAALDGPAGLVAEMRDTYARRRAMVV
ESLRAIPGVTCAMPQGAFYAYPGIAGCLGKTSQGGRMLRTDEDFAIALLDEQHVACVQGSAFGKGPYLRLSCATDDETLR
EACARIATFVAGLG

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=389, Percent_Identity=26.7352185089974, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI169881279, Length=389, Percent_Identity=26.7352185089974, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI56713254, Length=381, Percent_Identity=25.7217847769029, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI56713256, Length=381, Percent_Identity=25.7217847769029, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169881281, Length=305, Percent_Identity=23.9344262295082, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI149944424, Length=215, Percent_Identity=27.906976744186, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=29.2929292929293, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=29.9465240641711, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=28.974358974359, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=385, Percent_Identity=27.012987012987, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=430, Percent_Identity=24.4186046511628, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=427, Percent_Identity=24.3559718969555, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=406, Percent_Identity=22.4137931034483, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=422, Percent_Identity=23.696682464455, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320317, Length=348, Percent_Identity=22.9885057471264, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573069, Length=394, Percent_Identity=25.1269035532995, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646114, Length=394, Percent_Identity=25.1269035532995, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573067, Length=394, Percent_Identity=25.1269035532995, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573065, Length=394, Percent_Identity=25.1269035532995, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859735, Length=310, Percent_Identity=25.1612903225806, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43701; Mature: 43701

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTGTGPAGVGVAEPGFAARTARLDSPATIAMAVRARALRAEGHQVLSLALGEPDFATP
CCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
HAVIEAAHRAALDGQTKYPPVDGTPALKAAIARKFERENGLAYTPAELMVSNGGKQVIFN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCCCHHHHHH
AFMATIDAGDEIVIPSPYWVSYPLAARLFGGVPVFAACREEDGFRLTAPALEAALSPRTR
HHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCEE
WVVLNFPNNPTGAVVTLADLEAISEVLRRYPQAWILSDEIYEHLVFDGARHHSLAAVAPD
EEEEECCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCHHHCCCC
LKSRILTLNGVSKSYAMTGWRIGYGGGPARLIRMMTRVQGNATSGVCSIAQAAAAAALDG
HHHHEEEEECCCCCCEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
PAGLVAEMRDTYARRRAMVVESLRAIPGVTCAMPQGAFYAYPGIAGCLGKTSQGGRMLRT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHCCCCCCCCEEEEC
DEDFAIALLDEQHVACVQGSAFGKGPYLRLSCATDDETLREACARIATFVAGLG
CCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVTGTGPAGVGVAEPGFAARTARLDSPATIAMAVRARALRAEGHQVLSLALGEPDFATP
CCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCH
HAVIEAAHRAALDGQTKYPPVDGTPALKAAIARKFERENGLAYTPAELMVSNGGKQVIFN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCHHHHCCCCCHHHHHH
AFMATIDAGDEIVIPSPYWVSYPLAARLFGGVPVFAACREEDGFRLTAPALEAALSPRTR
HHHHHHCCCCEEEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHCCCCEE
WVVLNFPNNPTGAVVTLADLEAISEVLRRYPQAWILSDEIYEHLVFDGARHHSLAAVAPD
EEEEECCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCHHHCCCC
LKSRILTLNGVSKSYAMTGWRIGYGGGPARLIRMMTRVQGNATSGVCSIAQAAAAAALDG
HHHHEEEEECCCCCCEECCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
PAGLVAEMRDTYARRRAMVVESLRAIPGVTCAMPQGAFYAYPGIAGCLGKTSQGGRMLRT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHCCCCCCCCEEEEC
DEDFAIALLDEQHVACVQGSAFGKGPYLRLSCATDDETLREACARIATFVAGLG
CCCEEEEEECCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]