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The map label for this gene is ispH [H]

Identifier: 162148872

GI number: 162148872

Start: 3195304

End: 3196371

Strand: Reverse

Name: ispH [H]

Synonym: GDI_3102

Alternate gene names: 162148872

Gene position: 3196371-3195304 (Counterclockwise)

Preceding gene: 162148877

Following gene: 162148871

Centisome position: 81.04

GC content: 68.91

Gene sequence:

>1068_bases
ATGCGCGGCCGGCCGGTCGCTGCCCCCGGCCTGTATCCTATACCGCTCGCCGGCCGTTTGGGGAACACCATGCCCGACCA
GATGATTCAGACTTCCGACACCGCTCCCTCCCAGGTCCCGATGCGGTCGCTGAAGGTGCTGCTGGCCGGCCCGCGCGGCT
TCTGCGCCGGCGTCGACCGTGCGATCCGCGTGGTCGAGGAAGCGATCCGCCGTTATGGCGCGCCGGTCTATGTCCGGCAC
GAAATCGTCCATAACCGTACCGTCGTCGAGGAACTGGAGGCCCAGGGCGCCATCTTCGTCGAGGAACTGGACGAGGTCCC
GGCCGACGGCCATGTCGTCTTCTCGGCCCATGGCGTGCCCAAGACCGTCCCGGCCGAGGCCGAGCGGCGCAACCTGCTGT
ACCTGGATGCGACCTGCCCGCTGGTATCCAAGGTCCATCGCGAGGCCGAGCGTCATTTCGCCGACGGCGGTCCGGAAAGC
CGGCATATCCTGATGATCGGCCATGCCGGCCACCCCGAGGTCGTGGGTACGATGGGCCAGTTGCCGCCCGGCGCCGTGAC
CCTGATCAACGATTCCGAGGAAGCGCGCACCGTCCAGCCGGCCGACCCCGCGCGCCTGGCCTTCATCACCCAGACCACGC
TGTCGGTCGACGACACGGCCGAGATCGTGGACATCCTGCGCAGCCGCTTTCCGCTGATCGAAGGGCCGAAGCGCGAGGAC
ATCTGCTACGCCACCACCAACCGGCAGGAAGCGGTCAAGGCCATCGCGCCGGGCTGCGACCTGGTGATCGTGATCGGCTC
GCCGAACTCCTCCAATTCCCAGCGCCTGCGCGAGGTCGCGGAACGCTCCGGCGCGCCGCGCGCCCTGCTGGTGCCGCGCC
TCAGCGACCTGGACTGGTCGGTGCTGGACGGGGTGAACACGCTGGGCATCACCGCCGGCGCCTCGGCGCCCGAGGCGCTG
GTGCAGGAAATGGTGACGGCGCTGGCCAAGCGCTTCACCCTGGAAATCGAGGAACGGACGGTCAAGGAAGAGAACGTGAC
CTTCCGCCTGCCGGCCCCGCTGGGCTAG

Upstream 100 bases:

>100_bases
TGTGTGGCACCGGCTGGACGGTTATGTCCAAATGCACCGGGGTCGCAGGAAAATGGCTTGCGCCATGGCCCCGCTTTGCG
TAGGGCCGGACAGCACCGGG

Downstream 100 bases:

>100_bases
GCCGGGCCCTTCCACGTGGCGGTCTACACGGATGTGTCGGACGGGGCGCTGCGCGCGTTCCTGTCCCTGTACGATATCGG
CGACCTGACGGCCTATCGCG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRGRPVAAPGLYPIPLAGRLGNTMPDQMIQTSDTAPSQVPMRSLKVLLAGPRGFCAGVDRAIRVVEEAIRRYGAPVYVRH
EIVHNRTVVEELEAQGAIFVEELDEVPADGHVVFSAHGVPKTVPAEAERRNLLYLDATCPLVSKVHREAERHFADGGPES
RHILMIGHAGHPEVVGTMGQLPPGAVTLINDSEEARTVQPADPARLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKRED
ICYATTNRQEAVKAIAPGCDLVIVIGSPNSSNSQRLREVAERSGAPRALLVPRLSDLDWSVLDGVNTLGITAGASAPEAL
VQEMVTALAKRFTLEIEERTVKEENVTFRLPAPLG

Sequences:

>Translated_355_residues
MRGRPVAAPGLYPIPLAGRLGNTMPDQMIQTSDTAPSQVPMRSLKVLLAGPRGFCAGVDRAIRVVEEAIRRYGAPVYVRH
EIVHNRTVVEELEAQGAIFVEELDEVPADGHVVFSAHGVPKTVPAEAERRNLLYLDATCPLVSKVHREAERHFADGGPES
RHILMIGHAGHPEVVGTMGQLPPGAVTLINDSEEARTVQPADPARLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKRED
ICYATTNRQEAVKAIAPGCDLVIVIGSPNSSNSQRLREVAERSGAPRALLVPRLSDLDWSVLDGVNTLGITAGASAPEAL
VQEMVTALAKRFTLEIEERTVKEENVTFRLPAPLG
>Mature_355_residues
MRGRPVAAPGLYPIPLAGRLGNTMPDQMIQTSDTAPSQVPMRSLKVLLAGPRGFCAGVDRAIRVVEEAIRRYGAPVYVRH
EIVHNRTVVEELEAQGAIFVEELDEVPADGHVVFSAHGVPKTVPAEAERRNLLYLDATCPLVSKVHREAERHFADGGPES
RHILMIGHAGHPEVVGTMGQLPPGAVTLINDSEEARTVQPADPARLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKRED
ICYATTNRQEAVKAIAPGCDLVIVIGSPNSSNSQRLREVAERSGAPRALLVPRLSDLDWSVLDGVNTLGITAGASAPEAL
VQEMVTALAKRFTLEIEERTVKEENVTFRLPAPLG

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=313, Percent_Identity=51.4376996805112, Blast_Score=311, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 38402; Mature: 38402

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRPVAAPGLYPIPLAGRLGNTMPDQMIQTSDTAPSQVPMRSLKVLLAGPRGFCAGVDR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHEEEECCCHHHHHHHH
AIRVVEEAIRRYGAPVYVRHEIVHNRTVVEELEAQGAIFVEELDEVPADGHVVFSAHGVP
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCEEEEEECCCC
KTVPAEAERRNLLYLDATCPLVSKVHREAERHFADGGPESRHILMIGHAGHPEVVGTMGQ
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCC
LPPGAVTLINDSEEARTVQPADPARLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKRED
CCCCEEEEECCCHHHCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
ICYATTNRQEAVKAIAPGCDLVIVIGSPNSSNSQRLREVAERSGAPRALLVPRLSDLDWS
EEEEECCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHH
VLDGVNTLGITAGASAPEALVQEMVTALAKRFTLEIEERTVKEENVTFRLPAPLG
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEHHHHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MRGRPVAAPGLYPIPLAGRLGNTMPDQMIQTSDTAPSQVPMRSLKVLLAGPRGFCAGVDR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHEEEECCCHHHHHHHH
AIRVVEEAIRRYGAPVYVRHEIVHNRTVVEELEAQGAIFVEELDEVPADGHVVFSAHGVP
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCCEEEEEECCCC
KTVPAEAERRNLLYLDATCPLVSKVHREAERHFADGGPESRHILMIGHAGHPEVVGTMGQ
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCC
LPPGAVTLINDSEEARTVQPADPARLAFITQTTLSVDDTAEIVDILRSRFPLIEGPKRED
CCCCEEEEECCCHHHCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
ICYATTNRQEAVKAIAPGCDLVIVIGSPNSSNSQRLREVAERSGAPRALLVPRLSDLDWS
EEEEECCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCHH
VLDGVNTLGITAGASAPEALVQEMVTALAKRFTLEIEERTVKEENVTFRLPAPLG
HHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHEEEHHHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA