Click here to switch to the map view.

The map label for this gene is tlpA [H]

Identifier: 162148740

GI number: 162148740

Start: 3055021

End: 3055629

Strand: Reverse

Name: tlpA [H]

Synonym: GDI_2968

Alternate gene names: 162148740

Gene position: 3055629-3055021 (Counterclockwise)

Preceding gene: 162148743

Following gene: 162148739

Centisome position: 77.47

GC content: 73.4

Gene sequence:

>609_bases
ATGCCCCAGATCCTGACGAAACGCGTTCTGACGGAACCCGTCGATCGCCGCGCCCTGCTTGCGAATGGCGGCACCCTACT
GGCCGCATGGCTCGGGTGCAATTCCATCCTCGCGCCTCGCGCCATGGCCGAGGAGGGCCCGGCCCCGGTCGCGCTGCCGA
CCCGGGCGGAGCATCCGCCGCGCGCGCTGCCGGACCTTGCCTTCACGGATGAGGGCGGAGCGACGCACCGGCCGGCCGAC
TGGCGCGGGCGGATCGTGGTACTGAATGTGTGGGCCACCTGGTGCCAGCCCTGCGTCGCCGAAATGCCCGCCCTGTCGGT
GCTGGCCCGGCAGGTGGCGCCTGCGGGCGACATCGCCGTCCTGCCCGTGTCGGTGGACCATGGCGGGGCCGCGACCGTGC
GCCGATTCTACCATGCCCATGGCATCGCGGGCCTGCCGGTCCTGTGCGACCCGGACATGCGCGTCCCGACCGCGCTGCAC
GAGGACGGGGTGCCCGTCAGCCTGGTGATCGACCGTGGCGGGCGCGAAATCCTGCGCATCAGCGGTCCCGTGCTGTGGGA
CGCGCCGGACCTGCCCGCCCGGCTGCGCCATCTGGCGGCCGGCGGGTGA

Upstream 100 bases:

>100_bases
GCATGATGGCCGAAGGGCCGCCCGCGAACCGGCCGCCCCACTGGGCGTTCGCCCGTGACGCGTCCTTGCCCGCACCATTT
TCTTCGTTCACAGACATTCC

Downstream 100 bases:

>100_bases
TGCCATGCGGCTTTCGCCGCATTCCCGCACGGGGTAAAGCTGCCCGACGGACGGAGCCGGCAGGGGGCGAAGACAGGTGA
GGGACGAAGCAGCGCGACGC

Product: Thiol:disulfide interchange protein tlpA

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPQILTKRVLTEPVDRRALLANGGTLLAAWLGCNSILAPRAMAEEGPAPVALPTRAEHPPRALPDLAFTDEGGATHRPAD
WRGRIVVLNVWATWCQPCVAEMPALSVLARQVAPAGDIAVLPVSVDHGGAATVRRFYHAHGIAGLPVLCDPDMRVPTALH
EDGVPVSLVIDRGGREILRISGPVLWDAPDLPARLRHLAAGG

Sequences:

>Translated_202_residues
MPQILTKRVLTEPVDRRALLANGGTLLAAWLGCNSILAPRAMAEEGPAPVALPTRAEHPPRALPDLAFTDEGGATHRPAD
WRGRIVVLNVWATWCQPCVAEMPALSVLARQVAPAGDIAVLPVSVDHGGAATVRRFYHAHGIAGLPVLCDPDMRVPTALH
EDGVPVSLVIDRGGREILRISGPVLWDAPDLPARLRHLAAGG
>Mature_201_residues
PQILTKRVLTEPVDRRALLANGGTLLAAWLGCNSILAPRAMAEEGPAPVALPTRAEHPPRALPDLAFTDEGGATHRPADW
RGRIVVLNVWATWCQPCVAEMPALSVLARQVAPAGDIAVLPVSVDHGGAATVRRFYHAHGIAGLPVLCDPDMRVPTALHE
DGVPVSLVIDRGGREILRISGPVLWDAPDLPARLRHLAAGG

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21433; Mature: 21302

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00104 EPSP_SYNTHASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQILTKRVLTEPVDRRALLANGGTLLAAWLGCNSILAPRAMAEEGPAPVALPTRAEHPP
CCHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCHHCCHHHHHCCCCCEEECCCCCCCC
RALPDLAFTDEGGATHRPADWRGRIVVLNVWATWCQPCVAEMPALSVLARQVAPAGDIAV
CCCCCCEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCEEE
LPVSVDHGGAATVRRFYHAHGIAGLPVLCDPDMRVPTALHEDGVPVSLVIDRGGREILRI
EEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHCCCCCCEEEEEECCCCEEEEE
SGPVLWDAPDLPARLRHLAAGG
CCCEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
PQILTKRVLTEPVDRRALLANGGTLLAAWLGCNSILAPRAMAEEGPAPVALPTRAEHPP
CHHHHHHHHHCCCCCEEEEECCCEEEEHHHCCCCHHCCHHHHHCCCCCEEECCCCCCCC
RALPDLAFTDEGGATHRPADWRGRIVVLNVWATWCQPCVAEMPALSVLARQVAPAGDIAV
CCCCCCEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHHHHHHCCCCCEEE
LPVSVDHGGAATVRRFYHAHGIAGLPVLCDPDMRVPTALHEDGVPVSLVIDRGGREILRI
EEEEECCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCHHCCCCCCEEEEEECCCCEEEEE
SGPVLWDAPDLPARLRHLAAGG
CCCEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]