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The map label for this gene is sbcB [H]

Identifier: 162148670

GI number: 162148670

Start: 2982708

End: 2984021

Strand: Direct

Name: sbcB [H]

Synonym: GDI_2897

Alternate gene names: 162148670

Gene position: 2982708-2984021 (Clockwise)

Preceding gene: 162148669

Following gene: 162148672

Centisome position: 75.62

GC content: 59.44

Gene sequence:

>1314_bases
TTGAACGAGGTGGCGCGCTTCGAAGCGCGCTCGCGCCTACAGCCACATGTGCTTCCCCATCCCTCGGCGCTGCGCACCAA
CGGGCTGTCGATCGAATCGCTAACCGACACCAACCTGCCGTCACACTACGCGATGGTGGGAGACATTCGGCGGATCCTCA
TGTCTTGGAGTCCGGCCGTCTTCGTCGGCTTCAACTCCATCCGCTTCGACGAAGAGATGCTTCGCCACGCACTCTTTCAG
TGTCTGTATCCGGCCTATCTGACGAGCAACCACCGCAACTGCCGAGCTGACGCGCTCAGTCTGGTGATGGCCGCTGATGC
CGTATCGCCCGCGCAGCTTGTCGTGCCGGTTAGTGAGGAGGGGCGAAGGACATTTCGTTTGCAACAGTTGGCGGCGGCGA
ATGGCCTCGTCCATGCCCGCGCGCACGACGCCATGTCGGATGTGCTTGCGACGATCGAGCTATGTCGACTGGTCCATCAG
CGGTCTCCGGATCTGTGGCAGCGGTTCGTTCGCTTCTCGAACAAGGCTACCGTCTCGGATTTTGTCGATGCCGAAGATGG
CTTCGTGCTCACCGAGTTCTATGGGGGGCAGGCTTATCACGCGCCAGTCGTCTGTATCGGCGTCGACCCCGATCAAGCGA
ACGGCCGACTTTGCCTCAGCCTTTATCACGACGTCGGCCAGCTTGCTAGAATGAGTGACGTCGAACTGCAGGCCCATCTG
GCGCAGAAGCCCAGTCCGATACGTCGCTTCAGGATCAACGCCGCGCCAACGCTGACCGCATTTTTCGATGCTCCTGAACA
TATGTTGGATGGCGGGTCCATCGGACACATCGAAGACCAAGCTCGTCGCGTGAAAGCGGACGCTGATCTGTGCACGCGCC
TTGTGGCCGCTTACATCGCCGCCCGCGAGCCATACCCGCTGTCGCCTCATCTCGAGGAGCGAATCTACAACGGCTTCCCA
GGGCCGGATGATGAGGGGCGCATGAACGCATTCCACCAAGTCTCATGGCCGGATCGTCTCTCTATCGTGCAAAGCTTGGA
AGACGAGCGTCTGCGGTGGTTTGGCTTGCGCCTGGTGTATTTCGAAGCCCGCAGAGTTCTTCCCGCAACGGTAAAGGTCG
AGATCGAGCGTCGCTTGGCGAACCAACTGGCGGGAGATGGATCCGGCTGTCTCACATACGAGCTAGCTTTGGCCGAAACG
AATAAGCTGATGGGGCAACAAACAGACCACGACGGTCTTCTCGCTCGATACCGCATCTATTTACAGGATCGTAGCGCGCA
GGCTGCTGCCTTCAGGGCGCAGATGGTTATTTAA

Upstream 100 bases:

>100_bases
CGCGCCCATGAGCTTCGTCTTCTTCGATACCGAGACTACGGGGCTCAAGCGCGGTTTCGATCAAATTCTCCACTTCGCGG
CGGTTCGCACCGACGCGAAC

Downstream 100 bases:

>100_bases
GCTATATTCATATCGATTTATGCGCATCGTAGACCGTGTAACGACCATGATGGGTCGGGAGCTGTCTTTGAGATCAATCT
TTCTTCAACGTCAGCTATTC

Product: exodeoxyribonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNEVARFEARSRLQPHVLPHPSALRTNGLSIESLTDTNLPSHYAMVGDIRRILMSWSPAVFVGFNSIRFDEEMLRHALFQ
CLYPAYLTSNHRNCRADALSLVMAADAVSPAQLVVPVSEEGRRTFRLQQLAAANGLVHARAHDAMSDVLATIELCRLVHQ
RSPDLWQRFVRFSNKATVSDFVDAEDGFVLTEFYGGQAYHAPVVCIGVDPDQANGRLCLSLYHDVGQLARMSDVELQAHL
AQKPSPIRRFRINAAPTLTAFFDAPEHMLDGGSIGHIEDQARRVKADADLCTRLVAAYIAAREPYPLSPHLEERIYNGFP
GPDDEGRMNAFHQVSWPDRLSIVQSLEDERLRWFGLRLVYFEARRVLPATVKVEIERRLANQLAGDGSGCLTYELALAET
NKLMGQQTDHDGLLARYRIYLQDRSAQAAAFRAQMVI

Sequences:

>Translated_437_residues
MNEVARFEARSRLQPHVLPHPSALRTNGLSIESLTDTNLPSHYAMVGDIRRILMSWSPAVFVGFNSIRFDEEMLRHALFQ
CLYPAYLTSNHRNCRADALSLVMAADAVSPAQLVVPVSEEGRRTFRLQQLAAANGLVHARAHDAMSDVLATIELCRLVHQ
RSPDLWQRFVRFSNKATVSDFVDAEDGFVLTEFYGGQAYHAPVVCIGVDPDQANGRLCLSLYHDVGQLARMSDVELQAHL
AQKPSPIRRFRINAAPTLTAFFDAPEHMLDGGSIGHIEDQARRVKADADLCTRLVAAYIAAREPYPLSPHLEERIYNGFP
GPDDEGRMNAFHQVSWPDRLSIVQSLEDERLRWFGLRLVYFEARRVLPATVKVEIERRLANQLAGDGSGCLTYELALAET
NKLMGQQTDHDGLLARYRIYLQDRSAQAAAFRAQMVI
>Mature_437_residues
MNEVARFEARSRLQPHVLPHPSALRTNGLSIESLTDTNLPSHYAMVGDIRRILMSWSPAVFVGFNSIRFDEEMLRHALFQ
CLYPAYLTSNHRNCRADALSLVMAADAVSPAQLVVPVSEEGRRTFRLQQLAAANGLVHARAHDAMSDVLATIELCRLVHQ
RSPDLWQRFVRFSNKATVSDFVDAEDGFVLTEFYGGQAYHAPVVCIGVDPDQANGRLCLSLYHDVGQLARMSDVELQAHL
AQKPSPIRRFRINAAPTLTAFFDAPEHMLDGGSIGHIEDQARRVKADADLCTRLVAAYIAAREPYPLSPHLEERIYNGFP
GPDDEGRMNAFHQVSWPDRLSIVQSLEDERLRWFGLRLVYFEARRVLPATVKVEIERRLANQLAGDGSGCLTYELALAET
NKLMGQQTDHDGLLARYRIYLQDRSAQAAAFRAQMVI

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=382, Percent_Identity=25.130890052356, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 49048; Mature: 49048

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVARFEARSRLQPHVLPHPSALRTNGLSIESLTDTNLPSHYAMVGDIRRILMSWSPAV
CCCHHHHHHHHCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEE
FVGFNSIRFDEEMLRHALFQCLYPAYLTSNHRNCRADALSLVMAADAVSPAQLVVPVSEE
EEECCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
GRRTFRLQQLAAANGLVHARAHDAMSDVLATIELCRLVHQRSPDLWQRFVRFSNKATVSD
CCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
FVDAEDGFVLTEFYGGQAYHAPVVCIGVDPDQANGRLCLSLYHDVGQLARMSDVELQAHL
HCCCCCCEEEEEECCCCEECCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHH
AQKPSPIRRFRINAAPTLTAFFDAPEHMLDGGSIGHIEDQARRVKADADLCTRLVAAYIA
HCCCCHHHEEEECCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
AREPYPLSPHLEERIYNGFPGPDDEGRMNAFHQVSWPDRLSIVQSLEDERLRWFGLRLVY
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEE
FEARRVLPATVKVEIERRLANQLAGDGSGCLTYELALAETNKLMGQQTDHDGLLARYRIY
EEHHHCCCCCEEEHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCCCCEEEEEEE
LQDRSAQAAAFRAQMVI
EECCCCHHHHHHHEECC
>Mature Secondary Structure
MNEVARFEARSRLQPHVLPHPSALRTNGLSIESLTDTNLPSHYAMVGDIRRILMSWSPAV
CCCHHHHHHHHCCCCCCCCCCCHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEE
FVGFNSIRFDEEMLRHALFQCLYPAYLTSNHRNCRADALSLVMAADAVSPAQLVVPVSEE
EEECCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCC
GRRTFRLQQLAAANGLVHARAHDAMSDVLATIELCRLVHQRSPDLWQRFVRFSNKATVSD
CCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
FVDAEDGFVLTEFYGGQAYHAPVVCIGVDPDQANGRLCLSLYHDVGQLARMSDVELQAHL
HCCCCCCEEEEEECCCCEECCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHH
AQKPSPIRRFRINAAPTLTAFFDAPEHMLDGGSIGHIEDQARRVKADADLCTRLVAAYIA
HCCCCHHHEEEECCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHH
AREPYPLSPHLEERIYNGFPGPDDEGRMNAFHQVSWPDRLSIVQSLEDERLRWFGLRLVY
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHEE
FEARRVLPATVKVEIERRLANQLAGDGSGCLTYELALAETNKLMGQQTDHDGLLARYRIY
EEHHHCCCCCEEEHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCCCCCCEEEEEEE
LQDRSAQAAAFRAQMVI
EECCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]