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The map label for this gene is slt [H]

Identifier: 162148636

GI number: 162148636

Start: 2951164

End: 2951667

Strand: Reverse

Name: slt [H]

Synonym: GDI_2863

Alternate gene names: 162148636

Gene position: 2951667-2951164 (Counterclockwise)

Preceding gene: 162148637

Following gene: 162148635

Centisome position: 74.84

GC content: 68.06

Gene sequence:

>504_bases
GTGCTGCGCATCGAGAGCGCCGGTGATCGGCAGGCCATATCGTCGGCGGGCGCCATGGGGCTGATGCAGATCATGCCCGG
CACGTGGCGTGACCTGCGCCATGCCCTCAGTCTCGGCGCCGATCCGTTCGACCCGCATGACAACATCGTCGCCGGCGCCG
CCTATCTGCGCTGGCTGCACGATCGTTATGGCGATGTCGGGTTTCTGGCCGCGTATAACGCGGGTCCTGGACGCTATGAC
GAGCATCTGGCGACCGGCAGACCGCTGCCCGACGAGACGCGGGCCTATGTGGCTGCGGTCGTGGGGCGGATGGGGGACGA
CGCCGCTCCGACCGTTCTCCGTCAGTCGCCGGACGCCCATTCGGTCGCTCGCACATCTGCCGAGAACCTGTTCGTCGGTC
CCGCGCAGGCTGCAACGAGCGGTGTGGCCATGGCCGGCGACAGTCTGGTCCCGGCTCCGCCCGCGGGACTTTTCGTTCCG
ACCGGATGGAGGCACGAACCATGA

Upstream 100 bases:

>100_bases
GCTGGCGCTCTCGCCGGTTCCGGTCCATGCACAGGATCTCGACGCACTGGTACGGGAGGCGGCCCGTCAGGCTGCTATCC
CGCCGTCATGGATACACGCC

Downstream 100 bases:

>100_bases
ACGCTTTCATGGTCTCGATCTACGCCTCTCCCCCTGGTTCAGTTTTGGATGGGTGCAGGAGGACGTTGGGGGAGGGGGTG
GCGTATAGGCAGGATAAAAG

Product: lytic murein transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MLRIESAGDRQAISSAGAMGLMQIMPGTWRDLRHALSLGADPFDPHDNIVAGAAYLRWLHDRYGDVGFLAAYNAGPGRYD
EHLATGRPLPDETRAYVAAVVGRMGDDAAPTVLRQSPDAHSVARTSAENLFVGPAQAATSGVAMAGDSLVPAPPAGLFVP
TGWRHEP

Sequences:

>Translated_167_residues
MLRIESAGDRQAISSAGAMGLMQIMPGTWRDLRHALSLGADPFDPHDNIVAGAAYLRWLHDRYGDVGFLAAYNAGPGRYD
EHLATGRPLPDETRAYVAAVVGRMGDDAAPTVLRQSPDAHSVARTSAENLFVGPAQAATSGVAMAGDSLVPAPPAGLFVP
TGWRHEP
>Mature_167_residues
MLRIESAGDRQAISSAGAMGLMQIMPGTWRDLRHALSLGADPFDPHDNIVAGAAYLRWLHDRYGDVGFLAAYNAGPGRYD
EHLATGRPLPDETRAYVAAVVGRMGDDAAPTVLRQSPDAHSVARTSAENLFVGPAQAATSGVAMAGDSLVPAPPAGLFVP
TGWRHEP

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 17614; Mature: 17614

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRIESAGDRQAISSAGAMGLMQIMPGTWRDLRHALSLGADPFDPHDNIVAGAAYLRWLH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DRYGDVGFLAAYNAGPGRYDEHLATGRPLPDETRAYVAAVVGRMGDDAAPTVLRQSPDAH
HHCCCEEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHH
SVARTSAENLFVGPAQAATSGVAMAGDSLVPAPPAGLFVPTGWRHEP
HHHHHCCCCEEECCHHHHHCCEEECCCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure
MLRIESAGDRQAISSAGAMGLMQIMPGTWRDLRHALSLGADPFDPHDNIVAGAAYLRWLH
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
DRYGDVGFLAAYNAGPGRYDEHLATGRPLPDETRAYVAAVVGRMGDDAAPTVLRQSPDAH
HHCCCEEEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHH
SVARTSAENLFVGPAQAATSGVAMAGDSLVPAPPAGLFVPTGWRHEP
HHHHHCCCCEEECCHHHHHCCEEECCCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]