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The map label for this gene is hup1 [H]

Identifier: 162148585

GI number: 162148585

Start: 2889988

End: 2890281

Strand: Direct

Name: hup1 [H]

Synonym: GDI_2811

Alternate gene names: 162148585

Gene position: 2889988-2890281 (Clockwise)

Preceding gene: 162148578

Following gene: 162148591

Centisome position: 73.27

GC content: 60.2

Gene sequence:

>294_bases
ATGCAAAAGGATAGTTTCATGAAGATTGCCGATCTGGTCGATCATATCGCCACCACCACCGACATAAGCAAAACCGATAC
CCGCAAGGTGCTGGACGCCCTGGTCGAGGCGATGACCGCTGCCGCCAAAGCGGGTGACGAAATCACCCTGCCGAACTTCG
GCAAGTTCAAGGTCAGGGAAGTCGCCGCCCGCGAAGGCCGCAACCCGGCCACGGGTGCGACCATCCAGATCGCAGCCTCG
CGCAAGCTGGCCTTCACGCCAGCCAAGGCACTCAAGGACAGCCTGAACGACTGA

Upstream 100 bases:

>100_bases
CCAGCATCCCATGACTGCGCGTTGGTCATCTCCCCCTCCCTGCAGGCTTGATGCCGCCATGATTCCCCCGTAACGGCAGA
GGCAACGGGCACAGGCCCGA

Downstream 100 bases:

>100_bases
CCTGCCGACAGGCAAAAGGCGGCGGACCCTGTCCGCCGCCCCTTCCCCATCATGCCAGTTTCTGATGATAGACGCGTTCA
TCCGACCTTCTCCATCAGCT

Product: DNA binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MQKDSFMKIADLVDHIATTTDISKTDTRKVLDALVEAMTAAAKAGDEITLPNFGKFKVREVAAREGRNPATGATIQIAAS
RKLAFTPAKALKDSLND

Sequences:

>Translated_97_residues
MQKDSFMKIADLVDHIATTTDISKTDTRKVLDALVEAMTAAAKAGDEITLPNFGKFKVREVAAREGRNPATGATIQIAAS
RKLAFTPAKALKDSLND
>Mature_97_residues
MQKDSFMKIADLVDHIATTTDISKTDTRKVLDALVEAMTAAAKAGDEITLPNFGKFKVREVAAREGRNPATGATIQIAAS
RKLAFTPAKALKDSLND

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=46.6666666666667, Blast_Score=81, Evalue=1e-17,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=43.8202247191011, Blast_Score=72, Evalue=5e-15,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10405; Mature: 10405

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKDSFMKIADLVDHIATTTDISKTDTRKVLDALVEAMTAAAKAGDEITLPNFGKFKVRE
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VAAREGRNPATGATIQIAASRKLAFTPAKALKDSLND
HHHHCCCCCCCCCEEEEECCCCEECCHHHHHHHCCCC
>Mature Secondary Structure
MQKDSFMKIADLVDHIATTTDISKTDTRKVLDALVEAMTAAAKAGDEITLPNFGKFKVRE
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VAAREGRNPATGATIQIAASRKLAFTPAKALKDSLND
HHHHCCCCCCCCCEEEEECCCCEECCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]