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The map label for this gene is yajO [H]

Identifier: 162148524

GI number: 162148524

Start: 2839937

End: 2841169

Strand: Direct

Name: yajO [H]

Synonym: GDI_2747

Alternate gene names: 162148524

Gene position: 2839937-2841169 (Clockwise)

Preceding gene: 162148517

Following gene: 162148528

Centisome position: 72.0

GC content: 63.67

Gene sequence:

>1233_bases
ATGATCCTCCGCCATGAAACTGCTCTTGTGGATGACGGCGCACAAGGCGCGGTGTCTACTTCTGATAGCATCATGCAAGA
ACGCGATGGGATCTTCCTACCGCGAGGCCCCTCCCCGGCGGCACTATGCCGCCACACCGCATCACGCGGTCCGTCTTTTT
TGCGGAGATTTCATACCATGAAATACAATCCACTCGGCCGCACCGGCCTCCTGGTTTCGGAACTCTGCCTCGGCACCATG
ACCTTCGGCGGTCAAGGGGGCATCTGGGAACAAATCGGCGGTCTCGCGCAGGAGAGCGCCGATGGCCTGGTCCGCGCCGC
ACTCGATGCCGGGATCAACTTCATCGACACCGCCAACGTCTATTCCACCGGATTATCGGAACAGATCACCGGTCAGGCCC
TGCGCAATCTTGGCGTGGCACGCGACGACGTCGTGGTTGCAACCAAGGTGCTGGGGCCGATGGGCGACGGTCCGAATGCG
CGCGGCGCCTCACGCACCCATATCATCGCGCAATGCCATGCCAGCCTGAAACGGCTGCAACTCGACCATATCGATCTCTA
CCAGATCCATGGCGTCGATCCTCTCACCCCCATCGAGGAAACGATGGAGGCACTGGATACGCTGGTCCGTTCGGGCGCGG
TCCGCTACGTCGGCGTCTCCAACTGGGCGGCCTGGCAGATCAGCAAGGCGCTGGGCATCGCCGAACGCAAGAACCTGGCG
ATGATCCGCTCGCTGCAAGCCTATTACACCATCGCCGGACGCGACCTGGAGCGCGAGATCGCGCCGATGCTGGCCGAGGA
GCAGGTCGGGCTGATGGTCTGGAGCCCGCTGGCGGGCGGCTTGCTGTCGGGCAAATATCATCGCGACGGCAGTTCCGTCT
CCGGCGACGGCCGTCGCGCCAGCTTCGATTTCCCACCGGTCAATCGCGACCGGGCCTTCGCCGTGATCGACGCCATGCGC
CCCATCGCCGAGGCGCATGGTCGCAGCGTGGCACAGATCGCCATCGCTTGGCTGCTGCACCGCGAGGTGGTCACCAGCGT
CATCATCGGCGCGAAACGTCCGGACCAGTTGCAGGACAATATCGCGGCCACCACTGTCACGCTGTCGCCCGAGGATCTGA
CGACGCTGGATGCGATCAGCGCCCTGCCGCCGGAATATCCGGGCTGGATGATCGAACGGCAAAGCGGCTATCGCGCCGGC
GCCAAGGCAGGAGAGTTGCCGAAGACATCGTAG

Upstream 100 bases:

>100_bases
TCGGAGCGGAACAGCATGAGGCCGGGCACGGCGGTCGGTGTGCGTCGCCCGGCTGCATGGCGCCCGATAAGATCGCGCAG
GTGGTCGATCGCGGACATTC

Downstream 100 bases:

>100_bases
TACGCGCAGGGGCCGACCGACGCCGGGAAGCCCCCTATTCGGCCTCAGAGCGAAGGTCGTCCGGGATTTCCTGCCGGAAG
AATGGTCCCCGACTGAGTCG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MILRHETALVDDGAQGAVSTSDSIMQERDGIFLPRGPSPAALCRHTASRGPSFLRRFHTMKYNPLGRTGLLVSELCLGTM
TFGGQGGIWEQIGGLAQESADGLVRAALDAGINFIDTANVYSTGLSEQITGQALRNLGVARDDVVVATKVLGPMGDGPNA
RGASRTHIIAQCHASLKRLQLDHIDLYQIHGVDPLTPIEETMEALDTLVRSGAVRYVGVSNWAAWQISKALGIAERKNLA
MIRSLQAYYTIAGRDLEREIAPMLAEEQVGLMVWSPLAGGLLSGKYHRDGSSVSGDGRRASFDFPPVNRDRAFAVIDAMR
PIAEAHGRSVAQIAIAWLLHREVVTSVIIGAKRPDQLQDNIAATTVTLSPEDLTTLDAISALPPEYPGWMIERQSGYRAG
AKAGELPKTS

Sequences:

>Translated_410_residues
MILRHETALVDDGAQGAVSTSDSIMQERDGIFLPRGPSPAALCRHTASRGPSFLRRFHTMKYNPLGRTGLLVSELCLGTM
TFGGQGGIWEQIGGLAQESADGLVRAALDAGINFIDTANVYSTGLSEQITGQALRNLGVARDDVVVATKVLGPMGDGPNA
RGASRTHIIAQCHASLKRLQLDHIDLYQIHGVDPLTPIEETMEALDTLVRSGAVRYVGVSNWAAWQISKALGIAERKNLA
MIRSLQAYYTIAGRDLEREIAPMLAEEQVGLMVWSPLAGGLLSGKYHRDGSSVSGDGRRASFDFPPVNRDRAFAVIDAMR
PIAEAHGRSVAQIAIAWLLHREVVTSVIIGAKRPDQLQDNIAATTVTLSPEDLTTLDAISALPPEYPGWMIERQSGYRAG
AKAGELPKTS
>Mature_410_residues
MILRHETALVDDGAQGAVSTSDSIMQERDGIFLPRGPSPAALCRHTASRGPSFLRRFHTMKYNPLGRTGLLVSELCLGTM
TFGGQGGIWEQIGGLAQESADGLVRAALDAGINFIDTANVYSTGLSEQITGQALRNLGVARDDVVVATKVLGPMGDGPNA
RGASRTHIIAQCHASLKRLQLDHIDLYQIHGVDPLTPIEETMEALDTLVRSGAVRYVGVSNWAAWQISKALGIAERKNLA
MIRSLQAYYTIAGRDLEREIAPMLAEEQVGLMVWSPLAGGLLSGKYHRDGSSVSGDGRRASFDFPPVNRDRAFAVIDAMR
PIAEAHGRSVAQIAIAWLLHREVVTSVIIGAKRPDQLQDNIAATTVTLSPEDLTTLDAISALPPEYPGWMIERQSGYRAG
AKAGELPKTS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=365, Percent_Identity=36.4383561643836, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI27436969, Length=360, Percent_Identity=36.6666666666667, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI27436964, Length=317, Percent_Identity=35.9621451104101, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI27436962, Length=317, Percent_Identity=35.6466876971609, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI27436971, Length=366, Percent_Identity=33.6065573770492, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI27436966, Length=317, Percent_Identity=35.3312302839117, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI223718702, Length=282, Percent_Identity=29.0780141843972, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=31.6176470588235, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI41152114, Length=282, Percent_Identity=29.7872340425532, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI223718708, Length=129, Percent_Identity=35.6589147286822, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI87081735, Length=318, Percent_Identity=40.251572327044, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1789375, Length=338, Percent_Identity=32.2485207100592, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=33.6363636363636, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=30.7471264367816, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788081, Length=286, Percent_Identity=29.020979020979, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994888, Length=285, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082198, Length=295, Percent_Identity=25.7627118644068, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786400, Length=278, Percent_Identity=24.4604316546763, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564128, Length=302, Percent_Identity=26.158940397351, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=184, Percent_Identity=30.9782608695652, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=330, Percent_Identity=30.6060606060606, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323998, Length=334, Percent_Identity=32.6347305389222, Blast_Score=146, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=30.5921052631579, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319951, Length=342, Percent_Identity=28.9473684210526, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=29.8039215686275, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321052, Length=150, Percent_Identity=35.3333333333333, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320576, Length=323, Percent_Identity=25.077399380805, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=28, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=28, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24646159, Length=246, Percent_Identity=31.3008130081301, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646155, Length=181, Percent_Identity=34.2541436464088, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 44081; Mature: 44081

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILRHETALVDDGAQGAVSTSDSIMQERDGIFLPRGPSPAALCRHTASRGPSFLRRFHTM
CEEECCCCEECCCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHC
KYNPLGRTGLLVSELCLGTMTFGGQGGIWEQIGGLAQESADGLVRAALDAGINFIDTANV
CCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCHH
YSTGLSEQITGQALRNLGVARDDVVVATKVLGPMGDGPNARGASRTHIIAQCHASLKRLQ
HHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
LDHIDLYQIHGVDPLTPIEETMEALDTLVRSGAVRYVGVSNWAAWQISKALGIAERKNLA
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
MIRSLQAYYTIAGRDLEREIAPMLAEEQVGLMVWSPLAGGLLSGKYHRDGSSVSGDGRRA
HHHHHHHHHEECCCCHHHHHHHHHHHHCCCEEEECCHHCHHHCCCCCCCCCCCCCCCCEE
SFDFPPVNRDRAFAVIDAMRPIAEAHGRSVAQIAIAWLLHREVVTSVIIGAKRPDQLQDN
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
IAATTVTLSPEDLTTLDAISALPPEYPGWMIERQSGYRAGAKAGELPKTS
CEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILRHETALVDDGAQGAVSTSDSIMQERDGIFLPRGPSPAALCRHTASRGPSFLRRFHTM
CEEECCCCEECCCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHC
KYNPLGRTGLLVSELCLGTMTFGGQGGIWEQIGGLAQESADGLVRAALDAGINFIDTANV
CCCCCCCHHHHHHHHHHHHHEECCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCHH
YSTGLSEQITGQALRNLGVARDDVVVATKVLGPMGDGPNARGASRTHIIAQCHASLKRLQ
HHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
LDHIDLYQIHGVDPLTPIEETMEALDTLVRSGAVRYVGVSNWAAWQISKALGIAERKNLA
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
MIRSLQAYYTIAGRDLEREIAPMLAEEQVGLMVWSPLAGGLLSGKYHRDGSSVSGDGRRA
HHHHHHHHHEECCCCHHHHHHHHHHHHCCCEEEECCHHCHHHCCCCCCCCCCCCCCCCEE
SFDFPPVNRDRAFAVIDAMRPIAEAHGRSVAQIAIAWLLHREVVTSVIIGAKRPDQLQDN
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCC
IAATTVTLSPEDLTTLDAISALPPEYPGWMIERQSGYRAGAKAGELPKTS
CEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]