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The map label for this gene is hchA [H]

Identifier: 162148511

GI number: 162148511

Start: 2827700

End: 2828578

Strand: Direct

Name: hchA [H]

Synonym: GDI_2733

Alternate gene names: 162148511

Gene position: 2827700-2828578 (Clockwise)

Preceding gene: 162148510

Following gene: 162148512

Centisome position: 71.69

GC content: 50.51

Gene sequence:

>879_bases
ATGCTCTACCGAATAAGTTCGTTATGGGGGCTCGTCATCGTTCTGGCGGTTAGCTCTACTTCCCAAGCTGCGCTAGCTGC
GGATGCCGGATCGAAACGTGTGCTCGTTATCCTTTCGAGCGCGCGCTACCTGGACCTGCAAAAGCACAAGAAATATGAAA
CTGGCTTTTATCTCAACGAACTAGCTGTGCCAGCGAAAGCACTTGTTACGGCTGGATATGATCTGGTCTTTACGAATCCC
AAGGGCAACATAGTAACCTGGGATCACCATTCAGCAAATGCTTTGTACTTCAATAAGGACTTAAAACAGGAACAGGAAGC
CGAGCATTTCGTTGAACATCTTTTAACAGTTCGACATCCGCGCTCTCTTTCCTCCGTAAGGAAGGAAGGAGTCGACGATT
ACGACGCTGTCTTCATTCCTGGCGGCCATGCCCCCATGCAGGATCTGGCGACCAACCCCGACTTGGGTGCGATATTGTCC
GAGTTTCATAAGCGGCATCGGATCACGGCGCTGATATGTCACGGCCCGATCGCGTTGCTTTCAACCCTTACCTCTCCTCA
ATCTTTCATGGAATCTCTAGAAGGTGGAAACCTTCGTCAGGCTCGCTCTGCGTCCCGGAACTGGATCTATCGCGGTTACC
ATATGACGGCCTTCTCGAATGCTGAAGAAAAAATCGTCGAAACATCGCGCCTGCATGCGCAAGTGAGGGTTACCCCAGCG
ACATCGCTACGACTGGCGGGAGCTTTCCTAGAAGATGCACCAATATGGAAACCAAACGTCGTCACCGATCGAGAATTGGT
TACCGGCCAGCAGCCATTTTCCGATGATGTCTTTACAAGAACACTTTTGTTGGCTTTGGCCCAAAAACGAAAAACATGA

Upstream 100 bases:

>100_bases
AGGCGGGAGAAGTCGTTCTCAGCGGAGCGCTTGGCCCTATGATTCCTCTTGAAGGCGATAGCCACTACTCCACGAATATC
GCCCACATGGGAACCGTCTC

Downstream 100 bases:

>100_bases
AACGGCCGCCGTTCGATCTGTGGCAGTTGCTGTGCGTGCGGGCAATCGCCGAGCACGGCAGTATCCACGGCGCGGCGCGC
TTCCTGAACACAAGGCAGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLYRISSLWGLVIVLAVSSTSQAALAADAGSKRVLVILSSARYLDLQKHKKYETGFYLNELAVPAKALVTAGYDLVFTNP
KGNIVTWDHHSANALYFNKDLKQEQEAEHFVEHLLTVRHPRSLSSVRKEGVDDYDAVFIPGGHAPMQDLATNPDLGAILS
EFHKRHRITALICHGPIALLSTLTSPQSFMESLEGGNLRQARSASRNWIYRGYHMTAFSNAEEKIVETSRLHAQVRVTPA
TSLRLAGAFLEDAPIWKPNVVTDRELVTGQQPFSDDVFTRTLLLALAQKRKT

Sequences:

>Translated_292_residues
MLYRISSLWGLVIVLAVSSTSQAALAADAGSKRVLVILSSARYLDLQKHKKYETGFYLNELAVPAKALVTAGYDLVFTNP
KGNIVTWDHHSANALYFNKDLKQEQEAEHFVEHLLTVRHPRSLSSVRKEGVDDYDAVFIPGGHAPMQDLATNPDLGAILS
EFHKRHRITALICHGPIALLSTLTSPQSFMESLEGGNLRQARSASRNWIYRGYHMTAFSNAEEKIVETSRLHAQVRVTPA
TSLRLAGAFLEDAPIWKPNVVTDRELVTGQQPFSDDVFTRTLLLALAQKRKT
>Mature_292_residues
MLYRISSLWGLVIVLAVSSTSQAALAADAGSKRVLVILSSARYLDLQKHKKYETGFYLNELAVPAKALVTAGYDLVFTNP
KGNIVTWDHHSANALYFNKDLKQEQEAEHFVEHLLTVRHPRSLSSVRKEGVDDYDAVFIPGGHAPMQDLATNPDLGAILS
EFHKRHRITALICHGPIALLSTLTSPQSFMESLEGGNLRQARSASRNWIYRGYHMTAFSNAEEKIVETSRLHAQVRVTPA
TSLRLAGAFLEDAPIWKPNVVTDRELVTGQQPFSDDVFTRTLLLALAQKRKT

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=254, Percent_Identity=25.1968503937008, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320742, Length=249, Percent_Identity=26.5060240963855, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 32490; Mature: 32490

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYRISSLWGLVIVLAVSSTSQAALAADAGSKRVLVILSSARYLDLQKHKKYETGFYLNE
CEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCEEHHHHCCCCCCEEHHH
LAVPAKALVTAGYDLVFTNPKGNIVTWDHHSANALYFNKDLKQEQEAEHFVEHLLTVRHP
HHCCHHHHHHCCCEEEEECCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
RSLSSVRKEGVDDYDAVFIPGGHAPMQDLATNPDLGAILSEFHKRHRITALICHGPIALL
HHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCEEEEEECCHHHHH
STLTSPQSFMESLEGGNLRQARSASRNWIYRGYHMTAFSNAEEKIVETSRLHAQVRVTPA
HHHCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHEEEEEECCC
TSLRLAGAFLEDAPIWKPNVVTDRELVTGQQPFSDDVFTRTLLLALAQKRKT
HHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYRISSLWGLVIVLAVSSTSQAALAADAGSKRVLVILSSARYLDLQKHKKYETGFYLNE
CEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEECCCCEEHHHHCCCCCCEEHHH
LAVPAKALVTAGYDLVFTNPKGNIVTWDHHSANALYFNKDLKQEQEAEHFVEHLLTVRHP
HHCCHHHHHHCCCEEEEECCCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
RSLSSVRKEGVDDYDAVFIPGGHAPMQDLATNPDLGAILSEFHKRHRITALICHGPIALL
HHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCEEEEEECCHHHHH
STLTSPQSFMESLEGGNLRQARSASRNWIYRGYHMTAFSNAEEKIVETSRLHAQVRVTPA
HHHCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHEEEEEECCC
TSLRLAGAFLEDAPIWKPNVVTDRELVTGQQPFSDDVFTRTLLLALAQKRKT
HHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA