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The map label for this gene is yodQ [H]

Identifier: 162148483

GI number: 162148483

Start: 2800576

End: 2801847

Strand: Reverse

Name: yodQ [H]

Synonym: GDI_2703

Alternate gene names: 162148483

Gene position: 2801847-2800576 (Counterclockwise)

Preceding gene: 162148484

Following gene: 162148482

Centisome position: 71.04

GC content: 65.57

Gene sequence:

>1272_bases
ATGTCTGCGACCCTGAGTGATGAAAAAATTCCGAGCGACGGGATCGAACGCACCGTCGACCGCGATTTCGATACGCTGCA
GGTGGCATTCCTGCGCGAGCTGGTGCGCGTGCCGTCGGACAATCCGCCAGGAGATTGCGCACCGCACGGTCGTTTTGCCG
CCGAACGCCTGGAGACGCTGGGGTTTGTAGTGGAACGGGACGTGGTGCCCCCGGATGTCCTGGAGCAGAGCGGCCTGCGC
AGCGCCACGAACCTGATCATAAGGCAGCGCTTCGGAAACGGGTACGGCCCGGTCGTCGCCCTGAACGCCCATGATGACGT
GGTGCCGCCGGGAGGCGGATGGACGCACGATCCCTATGCCGGCGTGATCGAAGAGGGTCGCCTGTACGGACGGGGGGCGG
CAGTTTCGAAATCCGATTTCGCGACCTTCGCCTTTGCCCTCCGGGCTCTGAACGCCCATGCCGAGGGCCTGCAAGGGCAG
GTGGAACTGCATTTCACCTACGACGAGGAAACCGGGGGCAGCGCGGGACCGGGCCGGTTGTTGGAACTGGGGATGACCCG
CCCGGATTATGTCATCAGCGCCGGCTTCACCTACGGGGTGATGATCGCGCACAAGGGCAGCCTGCAACTCGATGTGACGT
TCACGGGGAAATCGGCACATTCCGCATGGCCCGACACCGGTTGTGACGCCATCCAGGCGGCCTGTGGCGTGATGGTGGCG
CTATATGCCCATCGGGACGCACTGGCCGCCCGGCCGTCCATAATTCCCGGTATCGGCGCGCCGACGCTGGTCATCGGCAC
CATCAGCGGAGGCGTGGCCGCGAACGTCGTGCCGGAACAGGCGACGTTCCGGATAGAGCGGCGGATCATGCCGGACGAGG
ATGCGGATGAAGTGGAGCGGGAACTGCGCGACATCATTCTCCGGGCCGTAACGGTGGATGGAGTGACCTGCGCCGTATGC
CGTCATCTTCTGGCGCTTCCGCTGGTGCCCGAAAGCCGGCAGGCCCCTTTGGTCGCGGCACTTCAGGATGCGGCCGAAAC
CGTGGTCGGCGAGCGGATTCCGGCAGAGGGCATGCCCCTGTTCACGGATGCCCGCCTGTACAGCAATGCCGGATGCCCGA
CCGTCCTGTACGGGGCGGGGCCGCGTCGCCTCCAGGACGCCAACGGCCATCGGGCAGACGAACATGTGGTGCTGGAAGAC
ATGCGCCGGGCGACGAAAGTCGTGGCGATCGCCCTGTGGCGGCTGCTGGGTCGCCCCGGCACGCAATCATAA

Upstream 100 bases:

>100_bases
GCCGAACGCCCATTGTTTCGCTTTACGATTGAATTCGAACGGTATACAAATCGCATATAAAACGAAGACCGTGATGCGTA
TCCGAGCGAAAGGGCGGCCG

Downstream 100 bases:

>100_bases
CGAAAACGATCCGAAAATACCCTTAACCGCCTGCAACGCGGGTCCCCCGGAGTGGGATGGACCGATGGAGTCGACATGAA
TATCCGCAAGCTTGCTCTTT

Product: peptidase

Products: Acetate; Ornithine [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSATLSDEKIPSDGIERTVDRDFDTLQVAFLRELVRVPSDNPPGDCAPHGRFAAERLETLGFVVERDVVPPDVLEQSGLR
SATNLIIRQRFGNGYGPVVALNAHDDVVPPGGGWTHDPYAGVIEEGRLYGRGAAVSKSDFATFAFALRALNAHAEGLQGQ
VELHFTYDEETGGSAGPGRLLELGMTRPDYVISAGFTYGVMIAHKGSLQLDVTFTGKSAHSAWPDTGCDAIQAACGVMVA
LYAHRDALAARPSIIPGIGAPTLVIGTISGGVAANVVPEQATFRIERRIMPDEDADEVERELRDIILRAVTVDGVTCAVC
RHLLALPLVPESRQAPLVAALQDAAETVVGERIPAEGMPLFTDARLYSNAGCPTVLYGAGPRRLQDANGHRADEHVVLED
MRRATKVVAIALWRLLGRPGTQS

Sequences:

>Translated_423_residues
MSATLSDEKIPSDGIERTVDRDFDTLQVAFLRELVRVPSDNPPGDCAPHGRFAAERLETLGFVVERDVVPPDVLEQSGLR
SATNLIIRQRFGNGYGPVVALNAHDDVVPPGGGWTHDPYAGVIEEGRLYGRGAAVSKSDFATFAFALRALNAHAEGLQGQ
VELHFTYDEETGGSAGPGRLLELGMTRPDYVISAGFTYGVMIAHKGSLQLDVTFTGKSAHSAWPDTGCDAIQAACGVMVA
LYAHRDALAARPSIIPGIGAPTLVIGTISGGVAANVVPEQATFRIERRIMPDEDADEVERELRDIILRAVTVDGVTCAVC
RHLLALPLVPESRQAPLVAALQDAAETVVGERIPAEGMPLFTDARLYSNAGCPTVLYGAGPRRLQDANGHRADEHVVLED
MRRATKVVAIALWRLLGRPGTQS
>Mature_422_residues
SATLSDEKIPSDGIERTVDRDFDTLQVAFLRELVRVPSDNPPGDCAPHGRFAAERLETLGFVVERDVVPPDVLEQSGLRS
ATNLIIRQRFGNGYGPVVALNAHDDVVPPGGGWTHDPYAGVIEEGRLYGRGAAVSKSDFATFAFALRALNAHAEGLQGQV
ELHFTYDEETGGSAGPGRLLELGMTRPDYVISAGFTYGVMIAHKGSLQLDVTFTGKSAHSAWPDTGCDAIQAACGVMVAL
YAHRDALAARPSIIPGIGAPTLVIGTISGGVAANVVPEQATFRIERRIMPDEDADEVERELRDIILRAVTVDGVTCAVCR
HLLALPLVPESRQAPLVAALQDAAETVVGERIPAEGMPLFTDARLYSNAGCPTVLYGAGPRRLQDANGHRADEHVVLEDM
RRATKVVAIALWRLLGRPGTQS

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=386, Percent_Identity=24.3523316062176, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790395, Length=353, Percent_Identity=28.0453257790368, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788816, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17538642, Length=297, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538640, Length=298, Percent_Identity=26.510067114094, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24649206, Length=292, Percent_Identity=29.4520547945205, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24649202, Length=294, Percent_Identity=27.891156462585, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649204, Length=294, Percent_Identity=27.891156462585, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24649210, Length=297, Percent_Identity=26.9360269360269, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356353, Length=295, Percent_Identity=25.7627118644068, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24649212, Length=297, Percent_Identity=29.2929292929293, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649208, Length=298, Percent_Identity=26.510067114094, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16 [C]

Molecular weight: Translated: 45239; Mature: 45108

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATLSDEKIPSDGIERTVDRDFDTLQVAFLRELVRVPSDNPPGDCAPHGRFAAERLETL
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
GFVVERDVVPPDVLEQSGLRSATNLIIRQRFGNGYGPVVALNAHDDVVPPGGGWTHDPYA
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCH
GVIEEGRLYGRGAAVSKSDFATFAFALRALNAHAEGLQGQVELHFTYDEETGGSAGPGRL
HHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHH
LELGMTRPDYVISAGFTYGVMIAHKGSLQLDVTFTGKSAHSAWPDTGCDAIQAACGVMVA
EEECCCCCCEEEECCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
LYAHRDALAARPSIIPGIGAPTLVIGTISGGVAANVVPEQATFRIERRIMPDEDADEVER
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHCCCCCCCHHHHHH
ELRDIILRAVTVDGVTCAVCRHLLALPLVPESRQAPLVAALQDAAETVVGERIPAEGMPL
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
FTDARLYSNAGCPTVLYGAGPRRLQDANGHRADEHVVLEDMRRATKVVAIALWRLLGRPG
EECHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
TQS
CCC
>Mature Secondary Structure 
SATLSDEKIPSDGIERTVDRDFDTLQVAFLRELVRVPSDNPPGDCAPHGRFAAERLETL
CCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
GFVVERDVVPPDVLEQSGLRSATNLIIRQRFGNGYGPVVALNAHDDVVPPGGGWTHDPYA
HHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCH
GVIEEGRLYGRGAAVSKSDFATFAFALRALNAHAEGLQGQVELHFTYDEETGGSAGPGRL
HHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHH
LELGMTRPDYVISAGFTYGVMIAHKGSLQLDVTFTGKSAHSAWPDTGCDAIQAACGVMVA
EEECCCCCCEEEECCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
LYAHRDALAARPSIIPGIGAPTLVIGTISGGVAANVVPEQATFRIERRIMPDEDADEVER
HHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHCCCCCCCHHHHHH
ELRDIILRAVTVDGVTCAVCRHLLALPLVPESRQAPLVAALQDAAETVVGERIPAEGMPL
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCE
FTDARLYSNAGCPTVLYGAGPRRLQDANGHRADEHVVLEDMRRATKVVAIALWRLLGRPG
EECHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
TQS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-Acetyl-L-ornithine; H2O [C]

Specific reaction: N2-Acetyl-L-ornithine + H2O --> Acetate + Ornithine [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]