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The map label for this gene is gumH [H]

Identifier: 162148333

GI number: 162148333

Start: 2648054

End: 2649226

Strand: Direct

Name: gumH [H]

Synonym: GDI_2550

Alternate gene names: 162148333

Gene position: 2648054-2649226 (Clockwise)

Preceding gene: 162148332

Following gene: 162148334

Centisome position: 67.14

GC content: 68.54

Gene sequence:

>1173_bases
TTGAAAGTCCTGCATATCGTCCGCCAGTTCAACCCGTCGGTCGGCGGCCTGGAAGATTCAGTCCTGAACCTTGCACGCAT
CCAGCGCGACCTGCTGGGGATCGACGCCACGGTCCTGACCCTGGACCGGGTGTTCGGCGCCCCGGACCGACTGCCCGCGA
CCGACATCGTGCAGGGCGTGCCGGTCCGCCGTATCGCCTGGCGCGGGTCCACCCGCTATCCGCTGGCCCCCGGCGTGCTT
CGCCACCTGGGTGACGCCACGATCGTGCATGTGCACGCCATCGATTTCTTTTTCGATTTCCTGGCCGCGACACGCTGGCT
GCACGGGCGCACGCTGGTGGCCTCGACCCATGGCGGGTTCTTCCATACCAGCGCGCTACGCGCGATCAAGACGATGTGGT
TCCGGACCGTGACCCGCGCGTCCCTTCACGCCTATGCCCGGATCGTGGCATGCAGCCACAGCGACGCGCAGATGTTCGAG
CCCATCGCGGGCACGCGCCTGCTGACGATCGAGAACGGCATCGACCAGCGAAAATTCCGCGCCGCCGCCGCCGCCGATCC
CACCCGGACGATCGTCAGCTTCGGCCGGTTCGCGCGTCACAAGCAGATCGACCTGCTGTTTCCGCTGCTGGCGCGCCTGC
GCGCGGGCGGCGGGGACTGGCGGCTGATCGTGGCCGGCCGGCCCGCCGACCAGTCGGAGGCCGACCTGGCCGCCGCCGCC
CGCGCCGCCGGCGTGGCCGATGCGGTGCGCTTCGTCATCGCGCCGTCGGACAACGAACTGAAAACCCTTTTCGGTCAGGC
GAGTTATTACGGGTGCCTGTCCCGGCATGAAGGTTTCGGCCTGGCGGCGGTCGAGGCGCTGTCGGCGGGACTGATCCCGG
TGCTGAGCGATATCGTCCCCTTCCGCCGCCTGGTCGGGCAGACCGGCATGGGCATCGTCCGGCCGGCCGATGACGTGGAC
GGGCTGGCAGAGGAGATGCTGGCGCTTCATGCGCGCGGCGACGAGGCGTTGCGCAGCCTGCGCACGCACGCGATCAGGGA
GTCAGCCCATTATGACTGGAACGATGTCGCCCGCCGCTATACCGACATGTACGGAACGGTGCTGATGTCCGCCGGCAAGA
ATCCAGCCCCCCCGATCTCGCTGGACACGGCGCAAGGGGGCTCCCTGTCCTGA

Upstream 100 bases:

>100_bases
TCGATGGCCGAGGCCTCGGCCTCGGCGTTCCCCGGCGCGCATTATCGCGGCGAAACGACGCGACGCATCGCCCTGAATTA
CGATTCCTGAGGGACGCACA

Downstream 100 bases:

>100_bases
AAGCCCGCTTGTATATGCGCTCCTCCCGCCGTCCGGCGGTACTGGCCACGCTGGCGATGGCGACGATGGCGGCAGGAAGC
CATCCGGCCCGGGCCCAGTT

Product: glycosyl transferase protein

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKVLHIVRQFNPSVGGLEDSVLNLARIQRDLLGIDATVLTLDRVFGAPDRLPATDIVQGVPVRRIAWRGSTRYPLAPGVL
RHLGDATIVHVHAIDFFFDFLAATRWLHGRTLVASTHGGFFHTSALRAIKTMWFRTVTRASLHAYARIVACSHSDAQMFE
PIAGTRLLTIENGIDQRKFRAAAAADPTRTIVSFGRFARHKQIDLLFPLLARLRAGGGDWRLIVAGRPADQSEADLAAAA
RAAGVADAVRFVIAPSDNELKTLFGQASYYGCLSRHEGFGLAAVEALSAGLIPVLSDIVPFRRLVGQTGMGIVRPADDVD
GLAEEMLALHARGDEALRSLRTHAIRESAHYDWNDVARRYTDMYGTVLMSAGKNPAPPISLDTAQGGSLS

Sequences:

>Translated_390_residues
MKVLHIVRQFNPSVGGLEDSVLNLARIQRDLLGIDATVLTLDRVFGAPDRLPATDIVQGVPVRRIAWRGSTRYPLAPGVL
RHLGDATIVHVHAIDFFFDFLAATRWLHGRTLVASTHGGFFHTSALRAIKTMWFRTVTRASLHAYARIVACSHSDAQMFE
PIAGTRLLTIENGIDQRKFRAAAAADPTRTIVSFGRFARHKQIDLLFPLLARLRAGGGDWRLIVAGRPADQSEADLAAAA
RAAGVADAVRFVIAPSDNELKTLFGQASYYGCLSRHEGFGLAAVEALSAGLIPVLSDIVPFRRLVGQTGMGIVRPADDVD
GLAEEMLALHARGDEALRSLRTHAIRESAHYDWNDVARRYTDMYGTVLMSAGKNPAPPISLDTAQGGSLS
>Mature_390_residues
MKVLHIVRQFNPSVGGLEDSVLNLARIQRDLLGIDATVLTLDRVFGAPDRLPATDIVQGVPVRRIAWRGSTRYPLAPGVL
RHLGDATIVHVHAIDFFFDFLAATRWLHGRTLVASTHGGFFHTSALRAIKTMWFRTVTRASLHAYARIVACSHSDAQMFE
PIAGTRLLTIENGIDQRKFRAAAAADPTRTIVSFGRFARHKQIDLLFPLLARLRAGGGDWRLIVAGRPADQSEADLAAAA
RAAGVADAVRFVIAPSDNELKTLFGQASYYGCLSRHEGFGLAAVEALSAGLIPVLSDIVPFRRLVGQTGMGIVRPADDVD
GLAEEMLALHARGDEALRSLRTHAIRESAHYDWNDVARRYTDMYGTVLMSAGKNPAPPISLDTAQGGSLS

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Contrary to pimB, the mannosyltransferase pim

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 42384; Mature: 42384

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLHIVRQFNPSVGGLEDSVLNLARIQRDLLGIDATVLTLDRVFGAPDRLPATDIVQGV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCC
PVRRIAWRGSTRYPLAPGVLRHLGDATIVHVHAIDFFFDFLAATRWLHGRTLVASTHGGF
CCCEEEECCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
FHTSALRAIKTMWFRTVTRASLHAYARIVACSHSDAQMFEPIAGTRLLTIENGIDQRKFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCCEEEEECCCCCHHHHH
AAAAADPTRTIVSFGRFARHKQIDLLFPLLARLRAGGGDWRLIVAGRPADQSEADLAAAA
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHH
RAAGVADAVRFVIAPSDNELKTLFGQASYYGCLSRHEGFGLAAVEALSAGLIPVLSDIVP
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
FRRLVGQTGMGIVRPADDVDGLAEEMLALHARGDEALRSLRTHAIRESAHYDWNDVARRY
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
TDMYGTVLMSAGKNPAPPISLDTAQGGSLS
HHHHHHHHHHCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MKVLHIVRQFNPSVGGLEDSVLNLARIQRDLLGIDATVLTLDRVFGAPDRLPATDIVQGV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCC
PVRRIAWRGSTRYPLAPGVLRHLGDATIVHVHAIDFFFDFLAATRWLHGRTLVASTHGGF
CCCEEEECCCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
FHTSALRAIKTMWFRTVTRASLHAYARIVACSHSDAQMFEPIAGTRLLTIENGIDQRKFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCCCCEEEEECCCCCHHHHH
AAAAADPTRTIVSFGRFARHKQIDLLFPLLARLRAGGGDWRLIVAGRPADQSEADLAAAA
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHH
RAAGVADAVRFVIAPSDNELKTLFGQASYYGCLSRHEGFGLAAVEALSAGLIPVLSDIVP
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHH
FRRLVGQTGMGIVRPADDVDGLAEEMLALHARGDEALRSLRTHAIRESAHYDWNDVARRY
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
TDMYGTVLMSAGKNPAPPISLDTAQGGSLS
HHHHHHHHHHCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12068013 [H]