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The map label for this gene is nuoA

Identifier: 162148254

GI number: 162148254

Start: 2562147

End: 2562590

Strand: Reverse

Name: nuoA

Synonym: GDI_2471

Alternate gene names: 162148254

Gene position: 2562590-2562147 (Counterclockwise)

Preceding gene: 162148255

Following gene: 162148253

Centisome position: 64.97

GC content: 67.34

Gene sequence:

>444_bases
GTGTTGGCCATGTCGGACTTCTGCACGCAGCATCCGCTCTTTTCCTATGCCGTGGCGATCGTGGTCCTGCTGGCCGCGAT
GCTGGGCCTGGGGGCGGTTTCCGGGACCCGGCGCGTCGGCGCGGCACGTGGGCGGTCGATGGACCTGCCGTTCGAATCCG
GTGTCCTGCCGGTCGGTTCGGCGCATTTGCGCATCCCGGTGCAATATTACCTGGTTGCGATGCTCTTCGTCATATTCGAC
GTGGAATCGGTTTTCCTGTTTTCGTGGGCACCGGTGGCGGTCGGCGCCGGGTGGCGCGGCTATGGCGCGGTGGTGGTGTT
CGTCGCCTCGCTGGCGGCGGCGCTGGCCTATGTGTGGCGGTGGGGCGCGCTGGACTGGGGCCCTGTTCCCCGTCGCCGGA
TAGACTATCGCAGGGCGGGGGACGCATCATGCGCTGGTCGCTGA

Upstream 100 bases:

>100_bases
ACACGGACGCGTGAACGGGGTAAAAAAGGGTGAACCCGGTCCGGGCAGGGCACGTTAACCGCAGAACATTCCGTCATTTT
CGGTCACTTCAACCTCAGCG

Downstream 100 bases:

>100_bases
CCCGACCGGGCGAGGAACCCGGCACGCCGCGCGACGCGACCATGACCGAAACCGTGAAACGCAACCTGGTGATGGGGCGG
TTGCAGGATTTCGTGTCCTG

Product: NADH-quinone oxidoreductase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MLAMSDFCTQHPLFSYAVAIVVLLAAMLGLGAVSGTRRVGAARGRSMDLPFESGVLPVGSAHLRIPVQYYLVAMLFVIFD
VESVFLFSWAPVAVGAGWRGYGAVVVFVASLAAALAYVWRWGALDWGPVPRRRIDYRRAGDASCAGR

Sequences:

>Translated_147_residues
MLAMSDFCTQHPLFSYAVAIVVLLAAMLGLGAVSGTRRVGAARGRSMDLPFESGVLPVGSAHLRIPVQYYLVAMLFVIFD
VESVFLFSWAPVAVGAGWRGYGAVVVFVASLAAALAYVWRWGALDWGPVPRRRIDYRRAGDASCAGR
>Mature_147_residues
MLAMSDFCTQHPLFSYAVAIVVLLAAMLGLGAVSGTRRVGAARGRSMDLPFESGVLPVGSAHLRIPVQYYLVAMLFVIFD
VESVFLFSWAPVAVGAGWRGYGAVVVFVASLAAALAYVWRWGALDWGPVPRRRIDYRRAGDASCAGR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=94, Percent_Identity=51.063829787234, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_GLUDA (A9HNA0)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001602715.1
- RefSeq:   YP_002275123.1
- GeneID:   5789121
- GeneID:   6974115
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_0718
- HOGENOM:   HBG605540
- OMA:   AWAVAFR
- ProtClustDB:   CLSK2403165
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 15854; Mature: 15854

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16dd986c)-; HASH(0x14da9344)-; HASH(0x1701e088)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAMSDFCTQHPLFSYAVAIVVLLAAMLGLGAVSGTRRVGAARGRSMDLPFESGVLPVGS
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
AHLRIPVQYYLVAMLFVIFDVESVFLFSWAPVAVGAGWRGYGAVVVFVASLAAALAYVWR
CEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
WGALDWGPVPRRRIDYRRAGDASCAGR
HCCCCCCCCCCHHHCCCCCCCCCCCCH
>Mature Secondary Structure
MLAMSDFCTQHPLFSYAVAIVVLLAAMLGLGAVSGTRRVGAARGRSMDLPFESGVLPVGS
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCC
AHLRIPVQYYLVAMLFVIFDVESVFLFSWAPVAVGAGWRGYGAVVVFVASLAAALAYVWR
CEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
WGALDWGPVPRRRIDYRRAGDASCAGR
HCCCCCCCCCCHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA