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The map label for this gene is arpC [H]

Identifier: 162148222

GI number: 162148222

Start: 2527968

End: 2529485

Strand: Direct

Name: arpC [H]

Synonym: GDI_2439

Alternate gene names: 162148222

Gene position: 2527968-2529485 (Clockwise)

Preceding gene: 162148221

Following gene: 162148223

Centisome position: 64.09

GC content: 70.09

Gene sequence:

>1518_bases
ATGACCGCCCGTACCGCCCGGCGTTGGCCGGCCCGGGGGGCAACCCTGATGTGCGGTGCCGGCCTGCTGGCCGGCCTGCC
GGTCCTGGGCGGCTGCTCCGTGGGGCCGGACTTCCGGCACCCCGCCGCACCGTCCACCCATTTCGCCCAGGCGGGGCGCC
CCGCCCATACCGACAGCACGGCCGACGCGGACGGCATGGCCCAGACCTTCAACCCCGGCCAGGACATTCCGGGGCAATGG
TGGACCTTGTTTCATTCCCCGGCCCTGGACCGCCTGGTCCGCCACGCGCTGGACCACAGCCCGACGCTGGAAGCCGCCAG
CCTGGCCCTGCGGGTGGCTCAGGAAAACCGCTCGGCAGCGGTGGGCGCCCTGTTTCCCAGCATCTCGGCCAGTTTCAACC
CGGCCCGGTTCAAGACGTCGCGCGTCTACTCGCCGGTGCCCAACAACAATAGCTGGCTGTATACCGTCCACACAGCGCAG
TTGAACATTTCCTACCAGCCGGATATCTGGGGCGGCATACGGCGCGGGATCGAGTCATCGTCCGCCCAGCGCGATGCCCT
GCGCTACCAGCTTGAGGCCGCGTACCTGACCCTGACGGGCGAAGTGGTGCAGGCGGCGGTCGGCTATGCCTCGCTGCGGG
CGCAGATCGACGCCGTGAAGGACCTGACCGCCGCCCAGCAACGGATTCTGGATTCCAGTATCCGCCAGCAGGCACTGGGC
CAGTTGGCGGATGCCGACGTGGCCATGCAGCGCGCCCAGTTGGCCCAGGACCAGGCCATGCTGGTGCCCCTGCAGCAGCA
ATTGCAGCAGCAGCACGACCATATCGCCGCCCTGACCGGCGACATGCCGGACGACCCGACGCCGGATTTCACGCTGGACG
CCTTCACCCTGCCCCAGGACCTGCCGGTCAGCCTGCCGGTGCGCCTGATCGACCAGCGCCCCGACATCAAGGTGGCCGAG
GCGAACTGGCACGCCGCCTGTGCCCAGGTGGGCGTGGCCGTGGCCAACCGCCTGCCCAACATCCAGTTGAGCGCGCAGCC
CGGCGTGGCCGCCGCGACCATCGCGCAATTGTTCACCCCCGGATACGGCCAGTGGATGCTGGCCGGCATGCTGAGCCAGC
CCCTGTTCCAGGGCGGACAGTTGCTGCATGAGGAACGCGCCGCCCGCGCGGCCTACAAGGAAAGTGCCGCGCAATACCGT
GCGGCGGTCGTGACCGCCGTGCAGGACGTCACCGACAGCCTGAACGCCGTCCGAGCCGATGCCTCGGCCCTGGCGGCCAA
TGCCAATGCCGAAAAGGCGGCAGCGCGCAGCCTGGGCATCACCCACGCGCGCCTGGGCCTGGGCGATGTCAGCCAGGTCG
CGCTGCTGACCGCCCAGCAGACCGAATTGCAGGCCCGCCTGGCCCTGGTCCAGGCCCGCGCCGCCCGCCTGTCCGACACT
GCCGGCCTGTTCCAGGCCCTGGGCGGTGGCTGGTGGAACCGGCAGGATATCCCGAGCGGCAAGAAACGGTCGGGCTGA

Upstream 100 bases:

>100_bases
CCCTGCTGACCCTGTTCATCCTGCCCACCTATTATTGCGAGTTGGAAGAATGGTGTGCCCGCCGCGACCCGCGCCGCGAA
GCCCGCAAGGGAGGCGTGAC

Downstream 100 bases:

>100_bases
TTCGCTGATCGCGGCATGGTGATCCGGAAGACGGGCAAAAAAACCCCGTCTCCAGCGCTATAGGGAGCGAACAAAAAGCA
CGGCCGATCAACGGCCGGCA

Product: efflux pump outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MTARTARRWPARGATLMCGAGLLAGLPVLGGCSVGPDFRHPAAPSTHFAQAGRPAHTDSTADADGMAQTFNPGQDIPGQW
WTLFHSPALDRLVRHALDHSPTLEAASLALRVAQENRSAAVGALFPSISASFNPARFKTSRVYSPVPNNNSWLYTVHTAQ
LNISYQPDIWGGIRRGIESSSAQRDALRYQLEAAYLTLTGEVVQAAVGYASLRAQIDAVKDLTAAQQRILDSSIRQQALG
QLADADVAMQRAQLAQDQAMLVPLQQQLQQQHDHIAALTGDMPDDPTPDFTLDAFTLPQDLPVSLPVRLIDQRPDIKVAE
ANWHAACAQVGVAVANRLPNIQLSAQPGVAAATIAQLFTPGYGQWMLAGMLSQPLFQGGQLLHEERAARAAYKESAAQYR
AAVVTAVQDVTDSLNAVRADASALAANANAEKAAARSLGITHARLGLGDVSQVALLTAQQTELQARLALVQARAARLSDT
AGLFQALGGGWWNRQDIPSGKKRSG

Sequences:

>Translated_505_residues
MTARTARRWPARGATLMCGAGLLAGLPVLGGCSVGPDFRHPAAPSTHFAQAGRPAHTDSTADADGMAQTFNPGQDIPGQW
WTLFHSPALDRLVRHALDHSPTLEAASLALRVAQENRSAAVGALFPSISASFNPARFKTSRVYSPVPNNNSWLYTVHTAQ
LNISYQPDIWGGIRRGIESSSAQRDALRYQLEAAYLTLTGEVVQAAVGYASLRAQIDAVKDLTAAQQRILDSSIRQQALG
QLADADVAMQRAQLAQDQAMLVPLQQQLQQQHDHIAALTGDMPDDPTPDFTLDAFTLPQDLPVSLPVRLIDQRPDIKVAE
ANWHAACAQVGVAVANRLPNIQLSAQPGVAAATIAQLFTPGYGQWMLAGMLSQPLFQGGQLLHEERAARAAYKESAAQYR
AAVVTAVQDVTDSLNAVRADASALAANANAEKAAARSLGITHARLGLGDVSQVALLTAQQTELQARLALVQARAARLSDT
AGLFQALGGGWWNRQDIPSGKKRSG
>Mature_504_residues
TARTARRWPARGATLMCGAGLLAGLPVLGGCSVGPDFRHPAAPSTHFAQAGRPAHTDSTADADGMAQTFNPGQDIPGQWW
TLFHSPALDRLVRHALDHSPTLEAASLALRVAQENRSAAVGALFPSISASFNPARFKTSRVYSPVPNNNSWLYTVHTAQL
NISYQPDIWGGIRRGIESSSAQRDALRYQLEAAYLTLTGEVVQAAVGYASLRAQIDAVKDLTAAQQRILDSSIRQQALGQ
LADADVAMQRAQLAQDQAMLVPLQQQLQQQHDHIAALTGDMPDDPTPDFTLDAFTLPQDLPVSLPVRLIDQRPDIKVAEA
NWHAACAQVGVAVANRLPNIQLSAQPGVAAATIAQLFTPGYGQWMLAGMLSQPLFQGGQLLHEERAARAAYKESAAQYRA
AVVTAVQDVTDSLNAVRADASALAANANAEKAAARSLGITHARLGLGDVSQVALLTAQQTELQARLALVQARAARLSDTA
GLFQALGGGWWNRQDIPSGKKRSG

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=478, Percent_Identity=24.0585774058577, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI2367348, Length=506, Percent_Identity=24.3083003952569, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53829; Mature: 53698

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTARRWPARGATLMCGAGLLAGLPVLGGCSVGPDFRHPAAPSTHFAQAGRPAHTDST
CCCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
ADADGMAQTFNPGQDIPGQWWTLFHSPALDRLVRHALDHSPTLEAASLALRVAQENRSAA
CCCCCCHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
VGALFPSISASFNPARFKTSRVYSPVPNNNSWLYTVHTAQLNISYQPDIWGGIRRGIESS
HHHHHHHHCCCCCCHHEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHCCCCC
SAQRDALRYQLEAAYLTLTGEVVQAAVGYASLRAQIDAVKDLTAAQQRILDSSIRQQALG
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLADADVAMQRAQLAQDQAMLVPLQQQLQQQHDHIAALTGDMPDDPTPDFTLDAFTLPQD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCC
LPVSLPVRLIDQRPDIKVAEANWHAACAQVGVAVANRLPNIQLSAQPGVAAATIAQLFTP
CCCCCCHHEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCC
GYGQWMLAGMLSQPLFQGGQLLHEERAARAAYKESAAQYRAAVVTAVQDVTDSLNAVRAD
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASALAANANAEKAAARSLGITHARLGLGDVSQVALLTAQQTELQARLALVQARAARLSDT
HHHHHCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLFQALGGGWWNRQDIPSGKKRSG
HHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TARTARRWPARGATLMCGAGLLAGLPVLGGCSVGPDFRHPAAPSTHFAQAGRPAHTDST
CCCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCC
ADADGMAQTFNPGQDIPGQWWTLFHSPALDRLVRHALDHSPTLEAASLALRVAQENRSAA
CCCCCCHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
VGALFPSISASFNPARFKTSRVYSPVPNNNSWLYTVHTAQLNISYQPDIWGGIRRGIESS
HHHHHHHHCCCCCCHHEECCCCCCCCCCCCCEEEEEEEEEEEEEECCCHHHHHHHCCCCC
SAQRDALRYQLEAAYLTLTGEVVQAAVGYASLRAQIDAVKDLTAAQQRILDSSIRQQALG
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLADADVAMQRAQLAQDQAMLVPLQQQLQQQHDHIAALTGDMPDDPTPDFTLDAFTLPQD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEECCCCC
LPVSLPVRLIDQRPDIKVAEANWHAACAQVGVAVANRLPNIQLSAQPGVAAATIAQLFTP
CCCCCCHHEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCC
GYGQWMLAGMLSQPLFQGGQLLHEERAARAAYKESAAQYRAAVVTAVQDVTDSLNAVRAD
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASALAANANAEKAAARSLGITHARLGLGDVSQVALLTAQQTELQARLALVQARAARLSDT
HHHHHCCCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLFQALGGGWWNRQDIPSGKKRSG
HHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]