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The map label for this gene is kat [H]

Identifier: 162148142

GI number: 162148142

Start: 2431047

End: 2433203

Strand: Reverse

Name: kat [H]

Synonym: GDI_2359

Alternate gene names: 162148142

Gene position: 2433203-2431047 (Counterclockwise)

Preceding gene: 162148143

Following gene: 162148140

Centisome position: 61.69

GC content: 65.28

Gene sequence:

>2157_bases
ATGAGCGTAAAATCACCAGGGACGAAATCGCCGGGTGCGAAATCACCCGGGCCGGGGCGCAAGACCGCCACGCTCGGGAC
CGAGACGATCCAGCGCGGGGCGGGTGGCGAGACGCATCAGGTGGCGGGGGGCGACGTGCCGGTCCTGACCACCCAGCAGG
GCATACCGGTCGCGGATGACCAGAATTCGGCCCGGATCGGGGCGAGGGGGCCGACCCTGCTGGAAGATTTCCATTTCCGC
GAGAAGATCTTCCATTTCGACCACGAGCGGATTCCCGAACGCGTGGTGCATGCGCGCGGCTATGGCGCGCACGGGTTCTT
CGAACTGACGGAATCGCTGGCCGACGTGACGCGCGCCGACGTGCTGCAGCGCCCGGGCGAGCGCGTTCCGGCCTTCGTGC
GGTTTTCCACCGTGGCGGGCAGCAAGGGATCGTCCGACCTGGCGCGTGACGTGCGCGGCTTCGCGGTCAAGCTGTACACG
CATGAAGGCAACTGGGACATTGTCGGCAACAATATCCCGGTCTTCTTCATCCAGGACGCCATCAAGTTTCCCGACGTGAT
CCATTCGGTGAAGCCCGAGCCGGATCGCGACTTTCCGCAGGCGCAGTCGGCGCACGACAATTTCTGGGATTTCGTGTCGC
TGTCGCCGGAATCGATCCACATGGCGCTGTGGGTGATGTCGGACCGCGCCATTCCCCGTTCGCTGCGGTTCATGGAAGGG
TTCGGCGTCCACTCCTTCCGCTTCGTGAACAAGGCGGGCAAATCGACCTACGTCAAATTCCATTGGAAGCCGAAGCAGGG
CCTGCAATCGGTGGTGTGGAACGAGGCCCTGAAGATCAACGGCGCCGATCCCGATTTTCATCGTCGTGACCTTTGGAACG
CCATCCAGTCCGGCGATTTTCCGGAATGGGAACTGGGCGTGCAACTGTTCGACGACGATTTCGCCGACAGTTTCGATTTC
GACGTCCTGGACCCGACCAAGCTGATTCCCGAGGAACTGGTGCCGGTGCGCCGGATCGGGCGGCTGGTGCTGGACCGGGT
CGTCGATAATTTCTTCGCCGAGACCGAGCAGGTGGCCTTCTGCACGCAGAACATCGTCCCGGGCGTGGATTTCACCAACG
ATCCGTTGCTGCAGGGGCGGAATTTTTCCTACCTCGACACGCAGCTCAAGCGCCTGGGCGGCCCCAACTTCACGCATATT
CCCATCAATGCCCCTAAATGTCCGTTTCACAATTTCCAGCAGGACGGGCACATGGCGATGCATAATCCGAAGGGCCGGGC
GAACTACGAACCCAATTCCTGGGGCGGCGCGCAGGGCGGCCCGCGTGAGGACCCGGCGCGCGGCTTCACTTCCTTCCCGG
CGCGCGAGGCGGGCGAGAAATTGCGGGAACGCTCCGAACTGTTCGGCGACCATTACAGCCAGGCCCGGCAATTCTACCTG
AGCCAGACCGAGACCGAGCGCGTTCACATCCAGCAGGCCTTCACCTTCGAACTGAGCAAGGTCGAGACGCCGCCGATCCG
TGCGCGGGTGGTGTCGCACCTGGTGAATGTCGATATCGACCTGGCCACCGCCGTGGCGCAGGGGCTGGGGCTGGAGGACC
TGCCCGAGGCCGCCCCGCCGGCCCGCCCGCTGGTGGACGGCCTGGCGCCCTCGCCGGCGCTGAGCATCCTGCGGAACGGT
CCCGACAGCTTCAAGGGGCGCAAGATCGGTATCCTGGTGACCGATGGCGTCGATGCCGGGCTGCTGAAGGCCGTCACCGA
TGCGGCGAGGGCCGAGGGCACGAACGTGGAACTGGTGGCGCCGAAGGTGGGCGGCGTGACGCTGCATGACGGCACGTTGG
TTCCGGCCGGGCAGAAGATCAATGGCGGCCCGTCGGTGCTGTACGACGCCGTGGTGCTGCTGCCCTCGGCGGACGGGGCC
ACCCTGCTGATGCAGGAGGCGACGGCGCGGGACTTCATCGCCGATGCCTACGCCCATGCCAAGTTCATCGGCTACGCCGA
GGCGGCGCTGCCGTTGATGGAACGCGCGGGGGTCCGCCCGGCCGACATGGATGACGGCATCCTTAAACTGTCCACGCCCG
CCGACGCGACCGCCTTCATCGCCGCGTGCAGGGCTCTGCGGTTCTGGGAGCGCGAGGCGAACGTCCACGCGGTATAG

Upstream 100 bases:

>100_bases
GGGGCCCGGCAAGGGGCAACCCTCCCTTTGCGCCCACGTTGGCGAACCAGGGGCATGGCGGCGCCGGTCGCCCCATGCCG
AAGGAAACAGAGGGGCTGTC

Downstream 100 bases:

>100_bases
GGCCTGCTAAAGGAACGAGACCGGATCGATATCGATGTCGATCCGGGCCCCGCGTTCGGGCGTCACGCGGTCCAGCCATT
GCCGCAGCAGGGGCTGGACC

Product: catalase HPII

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 718; Mature: 717

Protein sequence:

>718_residues
MSVKSPGTKSPGAKSPGPGRKTATLGTETIQRGAGGETHQVAGGDVPVLTTQQGIPVADDQNSARIGARGPTLLEDFHFR
EKIFHFDHERIPERVVHARGYGAHGFFELTESLADVTRADVLQRPGERVPAFVRFSTVAGSKGSSDLARDVRGFAVKLYT
HEGNWDIVGNNIPVFFIQDAIKFPDVIHSVKPEPDRDFPQAQSAHDNFWDFVSLSPESIHMALWVMSDRAIPRSLRFMEG
FGVHSFRFVNKAGKSTYVKFHWKPKQGLQSVVWNEALKINGADPDFHRRDLWNAIQSGDFPEWELGVQLFDDDFADSFDF
DVLDPTKLIPEELVPVRRIGRLVLDRVVDNFFAETEQVAFCTQNIVPGVDFTNDPLLQGRNFSYLDTQLKRLGGPNFTHI
PINAPKCPFHNFQQDGHMAMHNPKGRANYEPNSWGGAQGGPREDPARGFTSFPAREAGEKLRERSELFGDHYSQARQFYL
SQTETERVHIQQAFTFELSKVETPPIRARVVSHLVNVDIDLATAVAQGLGLEDLPEAAPPARPLVDGLAPSPALSILRNG
PDSFKGRKIGILVTDGVDAGLLKAVTDAARAEGTNVELVAPKVGGVTLHDGTLVPAGQKINGGPSVLYDAVVLLPSADGA
TLLMQEATARDFIADAYAHAKFIGYAEAALPLMERAGVRPADMDDGILKLSTPADATAFIAACRALRFWEREANVHAV

Sequences:

>Translated_718_residues
MSVKSPGTKSPGAKSPGPGRKTATLGTETIQRGAGGETHQVAGGDVPVLTTQQGIPVADDQNSARIGARGPTLLEDFHFR
EKIFHFDHERIPERVVHARGYGAHGFFELTESLADVTRADVLQRPGERVPAFVRFSTVAGSKGSSDLARDVRGFAVKLYT
HEGNWDIVGNNIPVFFIQDAIKFPDVIHSVKPEPDRDFPQAQSAHDNFWDFVSLSPESIHMALWVMSDRAIPRSLRFMEG
FGVHSFRFVNKAGKSTYVKFHWKPKQGLQSVVWNEALKINGADPDFHRRDLWNAIQSGDFPEWELGVQLFDDDFADSFDF
DVLDPTKLIPEELVPVRRIGRLVLDRVVDNFFAETEQVAFCTQNIVPGVDFTNDPLLQGRNFSYLDTQLKRLGGPNFTHI
PINAPKCPFHNFQQDGHMAMHNPKGRANYEPNSWGGAQGGPREDPARGFTSFPAREAGEKLRERSELFGDHYSQARQFYL
SQTETERVHIQQAFTFELSKVETPPIRARVVSHLVNVDIDLATAVAQGLGLEDLPEAAPPARPLVDGLAPSPALSILRNG
PDSFKGRKIGILVTDGVDAGLLKAVTDAARAEGTNVELVAPKVGGVTLHDGTLVPAGQKINGGPSVLYDAVVLLPSADGA
TLLMQEATARDFIADAYAHAKFIGYAEAALPLMERAGVRPADMDDGILKLSTPADATAFIAACRALRFWEREANVHAV
>Mature_717_residues
SVKSPGTKSPGAKSPGPGRKTATLGTETIQRGAGGETHQVAGGDVPVLTTQQGIPVADDQNSARIGARGPTLLEDFHFRE
KIFHFDHERIPERVVHARGYGAHGFFELTESLADVTRADVLQRPGERVPAFVRFSTVAGSKGSSDLARDVRGFAVKLYTH
EGNWDIVGNNIPVFFIQDAIKFPDVIHSVKPEPDRDFPQAQSAHDNFWDFVSLSPESIHMALWVMSDRAIPRSLRFMEGF
GVHSFRFVNKAGKSTYVKFHWKPKQGLQSVVWNEALKINGADPDFHRRDLWNAIQSGDFPEWELGVQLFDDDFADSFDFD
VLDPTKLIPEELVPVRRIGRLVLDRVVDNFFAETEQVAFCTQNIVPGVDFTNDPLLQGRNFSYLDTQLKRLGGPNFTHIP
INAPKCPFHNFQQDGHMAMHNPKGRANYEPNSWGGAQGGPREDPARGFTSFPAREAGEKLRERSELFGDHYSQARQFYLS
QTETERVHIQQAFTFELSKVETPPIRARVVSHLVNVDIDLATAVAQGLGLEDLPEAAPPARPLVDGLAPSPALSILRNGP
DSFKGRKIGILVTDGVDAGLLKAVTDAARAEGTNVELVAPKVGGVTLHDGTLVPAGQKINGGPSVLYDAVVLLPSADGAT
LLMQEATARDFIADAYAHAKFIGYAEAALPLMERAGVRPADMDDGILKLSTPADATAFIAACRALRFWEREANVHAV

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=489, Percent_Identity=41.7177914110429, Blast_Score=370, Evalue=1e-102,
Organism=Escherichia coli, GI48994891, Length=712, Percent_Identity=51.685393258427, Blast_Score=690, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=482, Percent_Identity=42.1161825726141, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25147792, Length=446, Percent_Identity=44.1704035874439, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25151141, Length=446, Percent_Identity=44.1704035874439, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321525, Length=531, Percent_Identity=35.969868173258, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6320462, Length=377, Percent_Identity=42.1750663129974, Blast_Score=303, Evalue=5e-83,
Organism=Drosophila melanogaster, GI17981717, Length=494, Percent_Identity=39.8785425101215, Blast_Score=355, Evalue=9e-98,
Organism=Drosophila melanogaster, GI19920968, Length=435, Percent_Identity=40, Blast_Score=333, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 78693; Mature: 78562

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKSPGTKSPGAKSPGPGRKTATLGTETIQRGAGGETHQVAGGDVPVLTTQQGIPVADD
CCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCC
QNSARIGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAHGFFELTESLADVTRAD
CCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VLQRPGERVPAFVRFSTVAGSKGSSDLARDVRGFAVKLYTHEGNWDIVGNNIPVFFIQDA
HHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCEEEEEEEECCCEEEECCCCCEEEECCH
IKFPDVIHSVKPEPDRDFPQAQSAHDNFWDFVSLSPESIHMALWVMSDRAIPRSLRFMEG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHC
FGVHSFRFVNKAGKSTYVKFHWKPKQGLQSVVWNEALKINGADPDFHRRDLWNAIQSGDF
CCCCHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCC
PEWELGVQLFDDDFADSFDFDVLDPTKLIPEELVPVRRIGRLVLDRVVDNFFAETEQVAF
CCHHHCCEEECCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTQNIVPGVDFTNDPLLQGRNFSYLDTQLKRLGGPNFTHIPINAPKCPFHNFQQDGHMAM
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEE
HNPKGRANYEPNSWGGAQGGPREDPARGFTSFPAREAGEKLRERSELFGDHYSQARQFYL
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQTETERVHIQQAFTFELSKVETPPIRARVVSHLVNVDIDLATAVAQGLGLEDLPEAAPP
CCCCCHHEEEEHHHEEEHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
ARPLVDGLAPSPALSILRNGPDSFKGRKIGILVTDGVDAGLLKAVTDAARAEGTNVELVA
CCHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
PKVGGVTLHDGTLVPAGQKINGGPSVLYDAVVLLPSADGATLLMQEATARDFIADAYAHA
CCCCCEEEECCEECCCCCCCCCCHHHHEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
KFIGYAEAALPLMERAGVRPADMDDGILKLSTPADATAFIAACRALRFWEREANVHAV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVKSPGTKSPGAKSPGPGRKTATLGTETIQRGAGGETHQVAGGDVPVLTTQQGIPVADD
CCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCC
QNSARIGARGPTLLEDFHFREKIFHFDHERIPERVVHARGYGAHGFFELTESLADVTRAD
CCCCEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
VLQRPGERVPAFVRFSTVAGSKGSSDLARDVRGFAVKLYTHEGNWDIVGNNIPVFFIQDA
HHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCEEEEEEEECCCEEEECCCCCEEEECCH
IKFPDVIHSVKPEPDRDFPQAQSAHDNFWDFVSLSPESIHMALWVMSDRAIPRSLRFMEG
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHC
FGVHSFRFVNKAGKSTYVKFHWKPKQGLQSVVWNEALKINGADPDFHRRDLWNAIQSGDF
CCCCHHHHHHHCCCCEEEEEEECHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCC
PEWELGVQLFDDDFADSFDFDVLDPTKLIPEELVPVRRIGRLVLDRVVDNFFAETEQVAF
CCHHHCCEEECCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTQNIVPGVDFTNDPLLQGRNFSYLDTQLKRLGGPNFTHIPINAPKCPFHNFQQDGHMAM
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEEE
HNPKGRANYEPNSWGGAQGGPREDPARGFTSFPAREAGEKLRERSELFGDHYSQARQFYL
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQTETERVHIQQAFTFELSKVETPPIRARVVSHLVNVDIDLATAVAQGLGLEDLPEAAPP
CCCCCHHEEEEHHHEEEHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
ARPLVDGLAPSPALSILRNGPDSFKGRKIGILVTDGVDAGLLKAVTDAARAEGTNVELVA
CCHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
PKVGGVTLHDGTLVPAGQKINGGPSVLYDAVVLLPSADGATLLMQEATARDFIADAYAHA
CCCCCEEEECCEECCCCCCCCCCHHHHEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
KFIGYAEAALPLMERAGVRPADMDDGILKLSTPADATAFIAACRALRFWEREANVHAV
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]