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The map label for this gene is xerC [H]

Identifier: 162148139

GI number: 162148139

Start: 2427578

End: 2428552

Strand: Reverse

Name: xerC [H]

Synonym: GDI_2356

Alternate gene names: 162148139

Gene position: 2428552-2427578 (Counterclockwise)

Preceding gene: 162148140

Following gene: 162148138

Centisome position: 61.57

GC content: 72.72

Gene sequence:

>975_bases
ATGACGGGCGCGGATCTGCGCGACGCCTTCCTGGACTGGATGCGGGACGAACGCCGGGCCTCGCCCCTGACGATCGCGGC
CTATCGCGGTGACCTGGACCGGTTCCTGGATTTCATCGGCGCCCATGTCGGCGGCACGGTGGACCTGGCGGTACTGGACC
GACTGTCGCTGGCGGACCTGCGGGCATGGCTGGCGTTCGAACATGCCCAGGGACATGCGCTGGCACAGCGCGACCGGGGG
CGGTCCAGCACGCCGGACCGTGCGGCGCGGACCCGGGCGCGGCGGGTGTCGGCCATGCGGTCCTTCTATCGCTATCTGGC
GCGGCGTCATGGCGTTACCAATCCGGCGCCCGGCCTGCTGGCCGCGCCGCGTACCAAATCCCCCCTGCCGCGCCCCTTGT
CCGAAGCGCAGGCCCTGGACGTGCCCGATGGTGTAGGGGACCTGGCGGTCACGCCCCTGGGGCAGGCGCGCGACGCGGCG
CTGTTCCTGCTGCTGTATGGCTGCGGATTGCGGATATCCGAGGCGCTGGGGCTGGATGTCCGGGATCTGGATCACGCGCT
GTCGGCGGGCGGCACGCTGCTGGTCCGGGGCAAGGGCGGGCGGGAACGGCTGGTGCCGATCCTGCCGGCGGTGGCGCGTG
TGCTGACGGACTGGCGGGCGCGGCATCCCGCGCCTCTGCCCGACGCGCCGCTCTTCCCCGGGGTGCGGGGCGGCCGGTTG
CAGCCGGCGGTGGCGCAGCGGGCGATGCGCGCCTGGCGCGACATGGCGGGCCTGCCGGACCACGCCACGCCCCATGCCCT
GCGCCATTCCTTCGCCACCCATCTGATGGAAGGCGGCGCGGATCTGCGCACGATCCAGGAATTGCTGGGCCATGCCAGCC
TGTCGACGACCCAGCGCTATACGCTGGCCGACGAGGCCCGGCTGATGGAAGTCTGGACCCGCGCCCATCCCCGCGCGGCA
CGTCCGGCAGAATGA

Upstream 100 bases:

>100_bases
GCCGGGGTGCGTTTGTCTAGACTCGCATGTGCCATGAGGTTTTCTATCGCCCCGGTCGTTTCCTGTCTTGTCCGCCGTCA
CGCGTGATGGGGGGCGGCGC

Downstream 100 bases:

>100_bases
AGGAGCGCAGATCGTGACCACGTCGCCCGCCTGTACGCTGTATCCGCCCATCGAACCCTACCGGTCCGGCCATCTGGAAA
CCGGCGACGGGCATCAGGTC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTGADLRDAFLDWMRDERRASPLTIAAYRGDLDRFLDFIGAHVGGTVDLAVLDRLSLADLRAWLAFEHAQGHALAQRDRG
RSSTPDRAARTRARRVSAMRSFYRYLARRHGVTNPAPGLLAAPRTKSPLPRPLSEAQALDVPDGVGDLAVTPLGQARDAA
LFLLLYGCGLRISEALGLDVRDLDHALSAGGTLLVRGKGGRERLVPILPAVARVLTDWRARHPAPLPDAPLFPGVRGGRL
QPAVAQRAMRAWRDMAGLPDHATPHALRHSFATHLMEGGADLRTIQELLGHASLSTTQRYTLADEARLMEVWTRAHPRAA
RPAE

Sequences:

>Translated_324_residues
MTGADLRDAFLDWMRDERRASPLTIAAYRGDLDRFLDFIGAHVGGTVDLAVLDRLSLADLRAWLAFEHAQGHALAQRDRG
RSSTPDRAARTRARRVSAMRSFYRYLARRHGVTNPAPGLLAAPRTKSPLPRPLSEAQALDVPDGVGDLAVTPLGQARDAA
LFLLLYGCGLRISEALGLDVRDLDHALSAGGTLLVRGKGGRERLVPILPAVARVLTDWRARHPAPLPDAPLFPGVRGGRL
QPAVAQRAMRAWRDMAGLPDHATPHALRHSFATHLMEGGADLRTIQELLGHASLSTTQRYTLADEARLMEVWTRAHPRAA
RPAE
>Mature_323_residues
TGADLRDAFLDWMRDERRASPLTIAAYRGDLDRFLDFIGAHVGGTVDLAVLDRLSLADLRAWLAFEHAQGHALAQRDRGR
SSTPDRAARTRARRVSAMRSFYRYLARRHGVTNPAPGLLAAPRTKSPLPRPLSEAQALDVPDGVGDLAVTPLGQARDAAL
FLLLYGCGLRISEALGLDVRDLDHALSAGGTLLVRGKGGRERLVPILPAVARVLTDWRARHPAPLPDAPLFPGVRGGRLQ
PAVAQRAMRAWRDMAGLPDHATPHALRHSFATHLMEGGADLRTIQELLGHASLSTTQRYTLADEARLMEVWTRAHPRAAR
PAE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=314, Percent_Identity=34.0764331210191, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789261, Length=320, Percent_Identity=35.625, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790768, Length=164, Percent_Identity=36.5853658536585, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790767, Length=165, Percent_Identity=31.5151515151515, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35400; Mature: 35269

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGADLRDAFLDWMRDERRASPLTIAAYRGDLDRFLDFIGAHVGGTVDLAVLDRLSLADL
CCCCHHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RAWLAFEHAQGHALAQRDRGRSSTPDRAARTRARRVSAMRSFYRYLARRHGVTNPAPGLL
HHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AAPRTKSPLPRPLSEAQALDVPDGVGDLAVTPLGQARDAALFLLLYGCGLRISEALGLDV
ECCCCCCCCCCCHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHCCCH
RDLDHALSAGGTLLVRGKGGRERLVPILPAVARVLTDWRARHPAPLPDAPLFPGVRGGRL
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPAVAQRAMRAWRDMAGLPDHATPHALRHSFATHLMEGGADLRTIQELLGHASLSTTQRY
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCHHH
TLADEARLMEVWTRAHPRAARPAE
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TGADLRDAFLDWMRDERRASPLTIAAYRGDLDRFLDFIGAHVGGTVDLAVLDRLSLADL
CCCHHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RAWLAFEHAQGHALAQRDRGRSSTPDRAARTRARRVSAMRSFYRYLARRHGVTNPAPGLL
HHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
AAPRTKSPLPRPLSEAQALDVPDGVGDLAVTPLGQARDAALFLLLYGCGLRISEALGLDV
ECCCCCCCCCCCHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHCCCH
RDLDHALSAGGTLLVRGKGGRERLVPILPAVARVLTDWRARHPAPLPDAPLFPGVRGGRL
HHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
QPAVAQRAMRAWRDMAGLPDHATPHALRHSFATHLMEGGADLRTIQELLGHASLSTTQRY
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHCCCHHH
TLADEARLMEVWTRAHPRAARPAE
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]