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The map label for this gene is mcpA [C]

Identifier: 162148127

GI number: 162148127

Start: 2414171

End: 2416054

Strand: Direct

Name: mcpA [C]

Synonym: GDI_2344

Alternate gene names: 162148127

Gene position: 2414171-2416054 (Clockwise)

Preceding gene: 162148126

Following gene: 162148134

Centisome position: 61.21

GC content: 62.53

Gene sequence:

>1884_bases
GTGCGCTTTTTCGGCATCAAGGTATCTTTAGGCCTCCTTTTCATACTCATCGCGCTGTCCTGCGTTTTTTCCGGAATATC
TTCGATAAGAGGGCTGACGCAGGTCAATCTCCGGGTAGAGGAGATCGCGCACAAATCGCTGGCGAACATCAGGGGCCTGG
CCGCGATCGACAGTCAGATCCGCGCTTTCCGGGGCGTCGAGATCAAGCAACTCGGGACATCCTCGCCAGAGGAGTTTGCG
ACTCTTTCCAGTTCCAGCGCCGCGATTTCCGATAAAATTGCGCATGCCATCGACGCGTACGTGCCCTTCATCCAGACCGA
CCAGGATCAGGTCCTGTTCCACAACCTTGAAACGCAGTGGGACGAGTACAAGGATTTCCACGACACCACATTCAAGAACT
GGGGCGCGGCCCACGACAGGACCCAGACCCTTGTCAACGAGGGGCAACGCCTGATCGAATTGCAGGAAACGGTTTCCGAA
ACGCTGACGTCCTTCATGAATGGAAACATACAGGACGCCGCCACCTACGCTTCGGAATCGGGGGCCACATACACGGCGAC
GCTGCGGCGGGTCTATGCGGCGTATGTCACGCTGTTCGTTTCCATGCTCATTTCCGGCCTTGTCGTGGTGCTGAACATTC
TTCGGCCGCTTCAGAAAATCAATGCATCCATCAGCAGGTTGGCAAAGGGCCAGACCGATCTGACGTTCCCGTGCGCGGAC
AGGAAGGATGAAATCGGCGATATTTCCCGGTCCCTGGACGTCTTCCGCGCCGCCGCCATCGCGAAGAGGGACCTGGAGCG
CGACGCCGAACTCCAGCGCCAGCGTGCCGACACCGAACGCGCTTCCATTCAGAAAAAAGCCGAAGCCGAAGCCAGCGAAT
GGCTGCGCAGGGCGACGGGCACCCTGGCGGCCGGCCTGAAACGGATGGCCGAGGGCGACCTGTCCTTCCAGATCGAGACC
CGGTTTTCAAAAGAGTTCGAGCCGCTGCGCGAGGATTTCAACCAGTCCCTGACCCAGCTTGCCGCGACGTTCGCCCAGAT
GTCGGGCGCCATTCAGGCCATCAGCAACGGCGCGCGCGAACTGGCGACCGGGGCCGACAACCTGGCGTCCCGGACCGAAC
GCCAGGCGACGGCCCTGGAGCAGACGGACGCCGCCGTGGCGGGCATTGCGCAAAGCGTGGGGGATACGGCCAGGCGATCC
GAAACCGCCCAGCAGATCGGCACGCAGGCGCGCCGGTCCGCCGCCGCGTCAAGCACGATCACGCATGCGACGGAAGAGGC
CATGAACCGCATCGAGAACGGCTCGGAACAGATTTCATCGGTTGTCGATGTGATCGAGAGCATTGCCTTCCAGACCAACA
TCCTGGCGCTGAATGCCAGCGTCGAGGCTGCCAGGGCCGGTGACGCGGGCCGGGGCTTCGCCGTGGTCGCCCACGAGGTC
CGGTCGCTGGCGCAGAAATGCGGCGAGGCCGCCGTGGATGTCAGGACCGTCATCCGCAATACCGCCGCCGACGTGAAGGA
AGGCTCGGGCCGCGTGAAGGAATGCAGCGGAACATTGCGGACGATCGTGGACTTCATCGGTCAGATGGGCCAGCACCTGG
ACGCCATAGCCGTCTCGGCCAGGGAACAATCCGCCAGCCTGACGGACATCACCGCCGCGATGGCCTCGCTGGGTCAGACG
ACCCAGCAGAATGCCGCCGTCGCGGAACAGTTCAACGCCGCGTCCTCCAGCCTCGCGAACGAAAGCCACCGGCTTAACGA
CCTTGTCGGGCAGTTCCACCTGCCGGAGCCGGCGGAAGACGAGTCCGGTCAGGACCTGGAGTTCATGGACGCTGATCTCC
CCAGCGCCAGCGCCAGCCCCCTTCGGTTTTCCGTCGGCAGATAA

Upstream 100 bases:

>100_bases
CTTCACAATTGGCGTCCCGGAAATCGCCTAGACTCATCCATGAATATGCGTCGCTTCGCGCGGACAAGCGGCCTGGGCAC
AAAAATCAACGAGGCAGCCA

Downstream 100 bases:

>100_bases
GAAGGAAGACCAGCGTCGCGATCAGGTCGAAAACGACCAGTGCCGGAACCACCACCCAGGCATTGGACCTGGCCAGAACG
AATTGGGGCAGCATCATCGG

Product: chemoreceptor mcpA (methyl-accepting chemotaxis protein)

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 627; Mature: 627

Protein sequence:

>627_residues
MRFFGIKVSLGLLFILIALSCVFSGISSIRGLTQVNLRVEEIAHKSLANIRGLAAIDSQIRAFRGVEIKQLGTSSPEEFA
TLSSSSAAISDKIAHAIDAYVPFIQTDQDQVLFHNLETQWDEYKDFHDTTFKNWGAAHDRTQTLVNEGQRLIELQETVSE
TLTSFMNGNIQDAATYASESGATYTATLRRVYAAYVTLFVSMLISGLVVVLNILRPLQKINASISRLAKGQTDLTFPCAD
RKDEIGDISRSLDVFRAAAIAKRDLERDAELQRQRADTERASIQKKAEAEASEWLRRATGTLAAGLKRMAEGDLSFQIET
RFSKEFEPLREDFNQSLTQLAATFAQMSGAIQAISNGARELATGADNLASRTERQATALEQTDAAVAGIAQSVGDTARRS
ETAQQIGTQARRSAAASSTITHATEEAMNRIENGSEQISSVVDVIESIAFQTNILALNASVEAARAGDAGRGFAVVAHEV
RSLAQKCGEAAVDVRTVIRNTAADVKEGSGRVKECSGTLRTIVDFIGQMGQHLDAIAVSAREQSASLTDITAAMASLGQT
TQQNAAVAEQFNAASSSLANESHRLNDLVGQFHLPEPAEDESGQDLEFMDADLPSASASPLRFSVGR

Sequences:

>Translated_627_residues
MRFFGIKVSLGLLFILIALSCVFSGISSIRGLTQVNLRVEEIAHKSLANIRGLAAIDSQIRAFRGVEIKQLGTSSPEEFA
TLSSSSAAISDKIAHAIDAYVPFIQTDQDQVLFHNLETQWDEYKDFHDTTFKNWGAAHDRTQTLVNEGQRLIELQETVSE
TLTSFMNGNIQDAATYASESGATYTATLRRVYAAYVTLFVSMLISGLVVVLNILRPLQKINASISRLAKGQTDLTFPCAD
RKDEIGDISRSLDVFRAAAIAKRDLERDAELQRQRADTERASIQKKAEAEASEWLRRATGTLAAGLKRMAEGDLSFQIET
RFSKEFEPLREDFNQSLTQLAATFAQMSGAIQAISNGARELATGADNLASRTERQATALEQTDAAVAGIAQSVGDTARRS
ETAQQIGTQARRSAAASSTITHATEEAMNRIENGSEQISSVVDVIESIAFQTNILALNASVEAARAGDAGRGFAVVAHEV
RSLAQKCGEAAVDVRTVIRNTAADVKEGSGRVKECSGTLRTIVDFIGQMGQHLDAIAVSAREQSASLTDITAAMASLGQT
TQQNAAVAEQFNAASSSLANESHRLNDLVGQFHLPEPAEDESGQDLEFMDADLPSASASPLRFSVGR
>Mature_627_residues
MRFFGIKVSLGLLFILIALSCVFSGISSIRGLTQVNLRVEEIAHKSLANIRGLAAIDSQIRAFRGVEIKQLGTSSPEEFA
TLSSSSAAISDKIAHAIDAYVPFIQTDQDQVLFHNLETQWDEYKDFHDTTFKNWGAAHDRTQTLVNEGQRLIELQETVSE
TLTSFMNGNIQDAATYASESGATYTATLRRVYAAYVTLFVSMLISGLVVVLNILRPLQKINASISRLAKGQTDLTFPCAD
RKDEIGDISRSLDVFRAAAIAKRDLERDAELQRQRADTERASIQKKAEAEASEWLRRATGTLAAGLKRMAEGDLSFQIET
RFSKEFEPLREDFNQSLTQLAATFAQMSGAIQAISNGARELATGADNLASRTERQATALEQTDAAVAGIAQSVGDTARRS
ETAQQIGTQARRSAAASSTITHATEEAMNRIENGSEQISSVVDVIESIAFQTNILALNASVEAARAGDAGRGFAVVAHEV
RSLAQKCGEAAVDVRTVIRNTAADVKEGSGRVKECSGTLRTIVDFIGQMGQHLDAIAVSAREQSASLTDITAAMASLGQT
TQQNAAVAEQFNAASSSLANESHRLNDLVGQFHLPEPAEDESGQDLEFMDADLPSASASPLRFSVGR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=35.9861591695502, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI2367378, Length=297, Percent_Identity=36.026936026936, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788194, Length=311, Percent_Identity=34.4051446945338, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788195, Length=293, Percent_Identity=34.1296928327645, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789453, Length=247, Percent_Identity=34.8178137651822, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67647; Mature: 67647

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFGIKVSLGLLFILIALSCVFSGISSIRGLTQVNLRVEEIAHKSLANIRGLAAIDSQI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFRGVEIKQLGTSSPEEFATLSSSSAAISDKIAHAIDAYVPFIQTDQDQVLFHNLETQW
HHHCCCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DEYKDFHDTTFKNWGAAHDRTQTLVNEGQRLIELQETVSETLTSFMNGNIQDAATYASES
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
GATYTATLRRVYAAYVTLFVSMLISGLVVVLNILRPLQKINASISRLAKGQTDLTFPCAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RKDEIGDISRSLDVFRAAAIAKRDLERDAELQRQRADTERASIQKKAEAEASEWLRRATG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAAGLKRMAEGDLSFQIETRFSKEFEPLREDFNQSLTQLAATFAQMSGAIQAISNGARE
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGADNLASRTERQATALEQTDAAVAGIAQSVGDTARRSETAQQIGTQARRSAAASSTI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THATEEAMNRIENGSEQISSVVDVIESIAFQTNILALNASVEAARAGDAGRGFAVVAHEV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHHHHH
RSLAQKCGEAAVDVRTVIRNTAADVKEGSGRVKECSGTLRTIVDFIGQMGQHLDAIAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQSASLTDITAAMASLGQTTQQNAAVAEQFNAASSSLANESHRLNDLVGQFHLPEPAED
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ESGQDLEFMDADLPSASASPLRFSVGR
CCCCCCHHHCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MRFFGIKVSLGLLFILIALSCVFSGISSIRGLTQVNLRVEEIAHKSLANIRGLAAIDSQI
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAFRGVEIKQLGTSSPEEFATLSSSSAAISDKIAHAIDAYVPFIQTDQDQVLFHNLETQW
HHHCCCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DEYKDFHDTTFKNWGAAHDRTQTLVNEGQRLIELQETVSETLTSFMNGNIQDAATYASES
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
GATYTATLRRVYAAYVTLFVSMLISGLVVVLNILRPLQKINASISRLAKGQTDLTFPCAD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RKDEIGDISRSLDVFRAAAIAKRDLERDAELQRQRADTERASIQKKAEAEASEWLRRATG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAAGLKRMAEGDLSFQIETRFSKEFEPLREDFNQSLTQLAATFAQMSGAIQAISNGARE
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATGADNLASRTERQATALEQTDAAVAGIAQSVGDTARRSETAQQIGTQARRSAAASSTI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THATEEAMNRIENGSEQISSVVDVIESIAFQTNILALNASVEAARAGDAGRGFAVVAHEV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCCCCCCCHHHHHHHH
RSLAQKCGEAAVDVRTVIRNTAADVKEGSGRVKECSGTLRTIVDFIGQMGQHLDAIAVSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQSASLTDITAAMASLGQTTQQNAAVAEQFNAASSSLANESHRLNDLVGQFHLPEPAED
HHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ESGQDLEFMDADLPSASASPLRFSVGR
CCCCCCHHHCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]