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The map label for this gene is mcpA [H]

Identifier: 162148109

GI number: 162148109

Start: 2392254

End: 2394020

Strand: Reverse

Name: mcpA [H]

Synonym: GDI_2326

Alternate gene names: 162148109

Gene position: 2394020-2392254 (Counterclockwise)

Preceding gene: 162148110

Following gene: 162148104

Centisome position: 60.7

GC content: 52.63

Gene sequence:

>1767_bases
GTGAATATTCGACCCAAGTTGTTTGTTATCAATATCGTGTCTGCGATATTGATATGCTCTTCTTTGATGTATATGGCGTC
AGGATTTTACGATACATCAAAAAAATATTCCATTCTATTTGATCAAGATCAGAATGGTATATTTGAGTTGGCGCGAGCAT
CAGATAAAATGAATGCTCTTTTTTATTCGATATATCGTATCGTCAATGCAACGGACTCGAATATAAAGACGAAATCGATC
GATTTGTTTCATAGTGATCTTCAAGGGCTGTACGATATTCTTGAAGATGCAGGCAGGCACCTGCCTTACATGAAAAGCGA
CATCGACCAGATCGTGCGCAGAGCAAAGCTGGAGATGAGCCGCGCCGACGGGGTCGTAATTCTGGATAATGACAGGCAGA
GAGCCGCGATCGTCAGTTATCTGGCGGACATGAACAATAAAGGACTCGATATCGCCATCGATCTGGGGCATCTGACCGAG
AAAGCGCGCGGTATCGCAGACCAGAAAAAGGCGGATCTGCACCGTCATGTGAGTGACGTTATTGAAATAAGCATCATGCT
CTGTCTTTCGGCAATAATTGCCGGGGTTCTTATTATCCTGTTTTTTTCCGCGTGGCAGATTACCGGGCCTATTTCTGCCC
TGGCCGAGACCATGAAGAAGATTTCAAAAGGAAATTACAATACGTCCATTCCTTTCCGGGATAAGCGGGACGAAATCGGC
ATCGTATCCAATGTTCTGTTCCATTTTCAGCAGAATTTGCAGAATGCCCGTCATCTGGAAAAGGAAGCCGCCAACCTGCG
TGAGGCCGCCGATGTGGAGAAGAAGCGCGTCGATGCTGAAAATGCTGAGCGGACGAAAATGCAGAAAGATCTGCTGGACG
GACTGGCGAGAGGCGTGAAAGCCTTGTCGCAAGGCGACCTGTCCTTTCGCTATACTGAGGCATTCCCGTGGGAGTTCGAA
GAACTCAGGGCTAATTTCAACGAGGCCCTGGTCTCGTTGTCCGATGCCATGCGCGACGTGTCGGACAGTGTTTCCGTTAT
CGCCAACAGTTCGAGCGAGGTATCCACAGCATCTGAAGACCTCGCGAAGCGTACCGAGCAGCAGGCCGCCAATCTGACGG
AAACCGCATCGTCGGTGACGTTCGTGGCGACGGCGGTGCAGAAAACAGCCGGAGCGGGGGCGGAGGCGCACGCGTCAGCA
CAACTGGCTCAGGATAACGCGACGCGATCCCGGGACATCATGACGACCCTGAGCCAGGCGATGGCGGAAATCACCGAATC
CTCGAAACAGGTTTTCGACATCATCAACCTGCTCGATGGCATCACGTTCCAGACGAACATTCTTGCCCTGAATGCGGCGG
TCGAGGCGGCCCGCGCGGGAGAAACGGGCAATGGATTTGCCGTCGTCGCCAGTGAAATCCGTTCCCTGGCCCAACGGTCG
GCGGATTCCACAAACGAAATCCGGGTCCTGATCAATCGATCGTCCGACGGGATAAGGAACGGCGCGCGGTTCGTCGATCA
GGCCAATGGCGCGGTGAAAGACATTGTGGACAGGATTCTCTTCATCACCGATTCGGTCAGTCAGATTGCCTCGGCCGCCA
AGGACCAAGCCTTCAGCATGTCCGAAATCAACACGACCGTCAGCCAGATGGACAAGGTGACGCAGCAGAATGCCGCGATG
GTGGAGCAGACGACGGCGGCGAGCCACAATCTGGCGTCCGAAGCCCGTAAGCTGAAGGCGATTGTCGACAGGTTCAAGGC
GGATTGA

Upstream 100 bases:

>100_bases
TGTAATGTGGCAAACCCTTTGCTGGTAAGCCGTACGAATGGCGGGCAACAAAGTGAGTGCAGTATAATATAATTAAACAA
CATATCGTGATGAGAAATAA

Downstream 100 bases:

>100_bases
CGGAAACCGGCACGCGGCCCGAACTGGCCCAGTAATATGGAAGCGCCAGAAAATTTTATGAAATGGTGAGCCGGGTGGGA
TTCGAACCCACGACCATTCG

Product: chemoreceptor mcpA

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNIRPKLFVINIVSAILICSSLMYMASGFYDTSKKYSILFDQDQNGIFELARASDKMNALFYSIYRIVNATDSNIKTKSI
DLFHSDLQGLYDILEDAGRHLPYMKSDIDQIVRRAKLEMSRADGVVILDNDRQRAAIVSYLADMNNKGLDIAIDLGHLTE
KARGIADQKKADLHRHVSDVIEISIMLCLSAIIAGVLIILFFSAWQITGPISALAETMKKISKGNYNTSIPFRDKRDEIG
IVSNVLFHFQQNLQNARHLEKEAANLREAADVEKKRVDAENAERTKMQKDLLDGLARGVKALSQGDLSFRYTEAFPWEFE
ELRANFNEALVSLSDAMRDVSDSVSVIANSSSEVSTASEDLAKRTEQQAANLTETASSVTFVATAVQKTAGAGAEAHASA
QLAQDNATRSRDIMTTLSQAMAEITESSKQVFDIINLLDGITFQTNILALNAAVEAARAGETGNGFAVVASEIRSLAQRS
ADSTNEIRVLINRSSDGIRNGARFVDQANGAVKDIVDRILFITDSVSQIASAAKDQAFSMSEINTTVSQMDKVTQQNAAM
VEQTTAASHNLASEARKLKAIVDRFKAD

Sequences:

>Translated_588_residues
MNIRPKLFVINIVSAILICSSLMYMASGFYDTSKKYSILFDQDQNGIFELARASDKMNALFYSIYRIVNATDSNIKTKSI
DLFHSDLQGLYDILEDAGRHLPYMKSDIDQIVRRAKLEMSRADGVVILDNDRQRAAIVSYLADMNNKGLDIAIDLGHLTE
KARGIADQKKADLHRHVSDVIEISIMLCLSAIIAGVLIILFFSAWQITGPISALAETMKKISKGNYNTSIPFRDKRDEIG
IVSNVLFHFQQNLQNARHLEKEAANLREAADVEKKRVDAENAERTKMQKDLLDGLARGVKALSQGDLSFRYTEAFPWEFE
ELRANFNEALVSLSDAMRDVSDSVSVIANSSSEVSTASEDLAKRTEQQAANLTETASSVTFVATAVQKTAGAGAEAHASA
QLAQDNATRSRDIMTTLSQAMAEITESSKQVFDIINLLDGITFQTNILALNAAVEAARAGETGNGFAVVASEIRSLAQRS
ADSTNEIRVLINRSSDGIRNGARFVDQANGAVKDIVDRILFITDSVSQIASAAKDQAFSMSEINTTVSQMDKVTQQNAAM
VEQTTAASHNLASEARKLKAIVDRFKAD
>Mature_588_residues
MNIRPKLFVINIVSAILICSSLMYMASGFYDTSKKYSILFDQDQNGIFELARASDKMNALFYSIYRIVNATDSNIKTKSI
DLFHSDLQGLYDILEDAGRHLPYMKSDIDQIVRRAKLEMSRADGVVILDNDRQRAAIVSYLADMNNKGLDIAIDLGHLTE
KARGIADQKKADLHRHVSDVIEISIMLCLSAIIAGVLIILFFSAWQITGPISALAETMKKISKGNYNTSIPFRDKRDEIG
IVSNVLFHFQQNLQNARHLEKEAANLREAADVEKKRVDAENAERTKMQKDLLDGLARGVKALSQGDLSFRYTEAFPWEFE
ELRANFNEALVSLSDAMRDVSDSVSVIANSSSEVSTASEDLAKRTEQQAANLTETASSVTFVATAVQKTAGAGAEAHASA
QLAQDNATRSRDIMTTLSQAMAEITESSKQVFDIINLLDGITFQTNILALNAAVEAARAGETGNGFAVVASEIRSLAQRS
ADSTNEIRVLINRSSDGIRNGARFVDQANGAVKDIVDRILFITDSVSQIASAAKDQAFSMSEINTTVSQMDKVTQQNAAM
VEQTTAASHNLASEARKLKAIVDRFKAD

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=38.2838283828383, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1788194, Length=237, Percent_Identity=43.4599156118143, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=38.255033557047, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI2367378, Length=219, Percent_Identity=44.2922374429224, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1789453, Length=241, Percent_Identity=36.5145228215768, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64477; Mature: 64477

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRPKLFVINIVSAILICSSLMYMASGFYDTSKKYSILFDQDQNGIFELARASDKMNAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
FYSIYRIVNATDSNIKTKSIDLFHSDLQGLYDILEDAGRHLPYMKSDIDQIVRRAKLEMS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RADGVVILDNDRQRAAIVSYLADMNNKGLDIAIDLGHLTEKARGIADQKKADLHRHVSDV
HCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHH
IEISIMLCLSAIIAGVLIILFFSAWQITGPISALAETMKKISKGNYNTSIPFRDKRDEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IVSNVLFHFQQNLQNARHLEKEAANLREAADVEKKRVDAENAERTKMQKDLLDGLARGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALSQGDLSFRYTEAFPWEFEELRANFNEALVSLSDAMRDVSDSVSVIANSSSEVSTASED
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAKRTEQQAANLTETASSVTFVATAVQKTAGAGAEAHASAQLAQDNATRSRDIMTTLSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
MAEITESSKQVFDIINLLDGITFQTNILALNAAVEAARAGETGNGFAVVASEIRSLAQRS
HHHHHHHHHHHHHHHHHHCCCCEEHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
ADSTNEIRVLINRSSDGIRNGARFVDQANGAVKDIVDRILFITDSVSQIASAAKDQAFSM
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHH
SEINTTVSQMDKVTQQNAAMVEQTTAASHNLASEARKLKAIVDRFKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIRPKLFVINIVSAILICSSLMYMASGFYDTSKKYSILFDQDQNGIFELARASDKMNAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
FYSIYRIVNATDSNIKTKSIDLFHSDLQGLYDILEDAGRHLPYMKSDIDQIVRRAKLEMS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RADGVVILDNDRQRAAIVSYLADMNNKGLDIAIDLGHLTEKARGIADQKKADLHRHVSDV
HCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHH
IEISIMLCLSAIIAGVLIILFFSAWQITGPISALAETMKKISKGNYNTSIPFRDKRDEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
IVSNVLFHFQQNLQNARHLEKEAANLREAADVEKKRVDAENAERTKMQKDLLDGLARGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ALSQGDLSFRYTEAFPWEFEELRANFNEALVSLSDAMRDVSDSVSVIANSSSEVSTASED
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LAKRTEQQAANLTETASSVTFVATAVQKTAGAGAEAHASAQLAQDNATRSRDIMTTLSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
MAEITESSKQVFDIINLLDGITFQTNILALNAAVEAARAGETGNGFAVVASEIRSLAQRS
HHHHHHHHHHHHHHHHHHCCCCEEHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
ADSTNEIRVLINRSSDGIRNGARFVDQANGAVKDIVDRILFITDSVSQIASAAKDQAFSM
CCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCHH
SEINTTVSQMDKVTQQNAAMVEQTTAASHNLASEARKLKAIVDRFKAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]