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The map label for this gene is pgk [H]

Identifier: 162148086

GI number: 162148086

Start: 2366024

End: 2367247

Strand: Direct

Name: pgk [H]

Synonym: GDI_2303

Alternate gene names: 162148086

Gene position: 2366024-2367247 (Clockwise)

Preceding gene: 162148085

Following gene: 162148091

Centisome position: 59.99

GC content: 69.04

Gene sequence:

>1224_bases
ATGGCGGCGCTGTCTTTCAAGACGCTGGATGCGCTCCAGCCCAAAGGACGCAAGGTCCTGCTGCGCGCGGACCTGAACGT
GCCCGTCCGCGACGGGAAGATCACGGACCTGACGCGCATCGAGCGCCTGGCCCCCACCATCCGCGAACTGGCGGACAAGG
GCGCGCGCGTGATCGTCGTCAGCCATTTCGACCGCCCGAAGGGCCAGCGGGTGCCGGAGATGTCGCTGGCGCCGATCGCG
GCCGCCCTGGGCACGACGCTGGGCCGTCCGGTGCAGTTCGCCGACGACTGCATCGGCCCGGTGGCCGAGGAAGCCGTTTC
CAAGCTCCAGGACGGCGACGTCCTGGTGCTGGAAAACACGCGCTTCCATGCCGGCGAGGAAAAGAACGACCCCGACCTGT
CCAAGGCGCTGGCCGCACTGGCGGATGACTACGTCAACGACGCGTTTTCCGCCGCCCATCGCGCCCATGCCTCGACCGAG
GGCGTCGCCCGCTTCCTGCCGTCCTTCGCCGGGCGGCTGATGGAGGCGGAACTGAACGCCCTGAACGTCGCGCTGGAAAA
CCCGGTCCGTCCGGTCGGCGCGATCGTCGGCGGCGCCAAGATCTCCACCAAGCTGGACCTGATCGGCAACCTGCTGGACA
AGGTCGACGTGCTGATCATCGGCGGCGCGATGGCCAACACGTTCCTGGCGGCCAACGGGGTGCGGGTCGGCAAGTCGCTG
CAGGAAGCGGACATGCACGACACGGCGCGCGCGATCATGGCCAAGGCCGAGGAACGCGGGTGCGAGATCGTGCTGCCGGT
CGATGCGGTGACGGCGACGGAATTCCGGGCCGATCCGCCGACCAGAACGGTGCCGATCGACGAGATCCCGGCGGATGCGA
TGATGCTGGATGCGGGGCCCGAGACGGTCACCCTGCTGATCCAGAAGATCGTGGGCCTGAAGACCCTGGTCTGGAACGGC
CCGCTGGGCGCGTTCGAACTGCATCCCTTCGACACCGCCACCAACCTGGTCGCGGCGGAAGTCGCGCGGCGGACCCAGGC
CGGCCAGTTGACCAGCGTCGCGGGCGGCGGGGACACGGTGTCCGCGCTGCGCCATGCCGGCGTGGCGGACGAAATGTCCT
ATACCTCGACCGCCGGCGGCGCGTTCCTGGAATGGCTGGAGGGCAAGGTTCTCCCGGGCATCCAGGCGCTGGGCGAAGTC
TCCGGGCGGATCCTGCCGCTCTGA

Upstream 100 bases:

>100_bases
TCGATGGCGGCAAGCTGGTCCGGGTGTGCAGCTGGTACGACAATGAATGGGGCTTTTCCAACCGCATGTCCGATACCGCA
GCGCTGTTCGGATCTCTGTG

Downstream 100 bases:

>100_bases
CGGAACGGGACGGTTCCCGGCGTCAGGCCGGGCCGTCCTCCTTTTCCTCCGTCGCCTCCCCGCCCTCTCGCGGGGTCAGG
CGCACGGAATCCCCGACCAG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAALSFKTLDALQPKGRKVLLRADLNVPVRDGKITDLTRIERLAPTIRELADKGARVIVVSHFDRPKGQRVPEMSLAPIA
AALGTTLGRPVQFADDCIGPVAEEAVSKLQDGDVLVLENTRFHAGEEKNDPDLSKALAALADDYVNDAFSAAHRAHASTE
GVARFLPSFAGRLMEAELNALNVALENPVRPVGAIVGGAKISTKLDLIGNLLDKVDVLIIGGAMANTFLAANGVRVGKSL
QEADMHDTARAIMAKAEERGCEIVLPVDAVTATEFRADPPTRTVPIDEIPADAMMLDAGPETVTLLIQKIVGLKTLVWNG
PLGAFELHPFDTATNLVAAEVARRTQAGQLTSVAGGGDTVSALRHAGVADEMSYTSTAGGAFLEWLEGKVLPGIQALGEV
SGRILPL

Sequences:

>Translated_407_residues
MAALSFKTLDALQPKGRKVLLRADLNVPVRDGKITDLTRIERLAPTIRELADKGARVIVVSHFDRPKGQRVPEMSLAPIA
AALGTTLGRPVQFADDCIGPVAEEAVSKLQDGDVLVLENTRFHAGEEKNDPDLSKALAALADDYVNDAFSAAHRAHASTE
GVARFLPSFAGRLMEAELNALNVALENPVRPVGAIVGGAKISTKLDLIGNLLDKVDVLIIGGAMANTFLAANGVRVGKSL
QEADMHDTARAIMAKAEERGCEIVLPVDAVTATEFRADPPTRTVPIDEIPADAMMLDAGPETVTLLIQKIVGLKTLVWNG
PLGAFELHPFDTATNLVAAEVARRTQAGQLTSVAGGGDTVSALRHAGVADEMSYTSTAGGAFLEWLEGKVLPGIQALGEV
SGRILPL
>Mature_406_residues
AALSFKTLDALQPKGRKVLLRADLNVPVRDGKITDLTRIERLAPTIRELADKGARVIVVSHFDRPKGQRVPEMSLAPIAA
ALGTTLGRPVQFADDCIGPVAEEAVSKLQDGDVLVLENTRFHAGEEKNDPDLSKALAALADDYVNDAFSAAHRAHASTEG
VARFLPSFAGRLMEAELNALNVALENPVRPVGAIVGGAKISTKLDLIGNLLDKVDVLIIGGAMANTFLAANGVRVGKSLQ
EADMHDTARAIMAKAEERGCEIVLPVDAVTATEFRADPPTRTVPIDEIPADAMMLDAGPETVTLLIQKIVGLKTLVWNGP
LGAFELHPFDTATNLVAAEVARRTQAGQLTSVAGGGDTVSALRHAGVADEMSYTSTAGGAFLEWLEGKVLPGIQALGEVS
GRILPL

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=413, Percent_Identity=43.0992736077482, Blast_Score=305, Evalue=5e-83,
Organism=Homo sapiens, GI31543397, Length=413, Percent_Identity=42.3728813559322, Blast_Score=295, Evalue=4e-80,
Organism=Escherichia coli, GI1789294, Length=386, Percent_Identity=44.8186528497409, Blast_Score=307, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17508823, Length=415, Percent_Identity=42.8915662650602, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6319857, Length=416, Percent_Identity=43.75, Blast_Score=293, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24581203, Length=416, Percent_Identity=40.8653846153846, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI17136394, Length=408, Percent_Identity=39.9509803921569, Blast_Score=262, Evalue=4e-70,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 42929; Mature: 42798

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALSFKTLDALQPKGRKVLLRADLNVPVRDGKITDLTRIERLAPTIRELADKGARVIVV
CCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
SHFDRPKGQRVPEMSLAPIAAALGTTLGRPVQFADDCIGPVAEEAVSKLQDGDVLVLENT
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEECC
RFHAGEEKNDPDLSKALAALADDYVNDAFSAAHRAHASTEGVARFLPSFAGRLMEAELNA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LNVALENPVRPVGAIVGGAKISTKLDLIGNLLDKVDVLIIGGAMANTFLAANGVRVGKSL
HHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHCCCCHHCCHH
QEADMHDTARAIMAKAEERGCEIVLPVDAVTATEFRADPPTRTVPIDEIPADAMMLDAGP
HHHHHHHHHHHHHHHHHHCCCEEEEECCCEEHHHHCCCCCCCCCCCCCCCCCEEEECCCC
ETVTLLIQKIVGLKTLVWNGPLGAFELHPFDTATNLVAAEVARRTQAGQLTSVAGGGDTV
HHHHHHHHHHHHHHHEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
SALRHAGVADEMSYTSTAGGAFLEWLEGKVLPGIQALGEVSGRILPL
HHHHHCCCHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AALSFKTLDALQPKGRKVLLRADLNVPVRDGKITDLTRIERLAPTIRELADKGARVIVV
CCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
SHFDRPKGQRVPEMSLAPIAAALGTTLGRPVQFADDCIGPVAEEAVSKLQDGDVLVLENT
EECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHCCCCCEEEEECC
RFHAGEEKNDPDLSKALAALADDYVNDAFSAAHRAHASTEGVARFLPSFAGRLMEAELNA
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LNVALENPVRPVGAIVGGAKISTKLDLIGNLLDKVDVLIIGGAMANTFLAANGVRVGKSL
HHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHCCCCHHCCHH
QEADMHDTARAIMAKAEERGCEIVLPVDAVTATEFRADPPTRTVPIDEIPADAMMLDAGP
HHHHHHHHHHHHHHHHHHCCCEEEEECCCEEHHHHCCCCCCCCCCCCCCCCCEEEECCCC
ETVTLLIQKIVGLKTLVWNGPLGAFELHPFDTATNLVAAEVARRTQAGQLTSVAGGGDTV
HHHHHHHHHHHHHHHEEECCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
SALRHAGVADEMSYTSTAGGAFLEWLEGKVLPGIQALGEVSGRILPL
HHHHHCCCHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA