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The map label for this gene is minC [H]

Identifier: 162148066

GI number: 162148066

Start: 2342996

End: 2343718

Strand: Direct

Name: minC [H]

Synonym: GDI_2283

Alternate gene names: 162148066

Gene position: 2342996-2343718 (Clockwise)

Preceding gene: 162148065

Following gene: 162148067

Centisome position: 59.4

GC content: 71.09

Gene sequence:

>723_bases
GTGACGCCCTTGTCCGACGATTTCCGACCGCCTCCCCGTATCCGAGCCCGCGGCCGTTCCTTCCTGGCGCTTGTGCTGTC
GCCCGAGGCCGGGCTGGATGACTGGCTGCGGGGGCTGGACGCACAGATCGCGCGCTCGCCGTCCTTCTTCGTCGGCAAGC
CGATCATTCTGGACCTCGGCCTGCTGTCGGGCGAAGCCGAGGGCCTGGCCGACCTGTACCCCGCCCTGCTGGAACGCGGG
GTGCGGATCATCGGGATCGAAGGGGGGGATTCCGCCTGGCCCGCCCTGGCCGGCTGGGACTGGCCGCAGGGATTCGAGGG
CGGCCGGGCCTCGGGCACCGTCGCCCTGCCCGAGGAAACGGATGGCGGCGAGGCCGCATCCGCCACCGCGCCGGCCGCGT
CGCTGATCGTCGAGCGGCCGGTACGCTCCGGCCAGTCGGTCCTGCATCATGACGGAGACGTGATCGTCATCGGGTCGGTG
GCCTCGGGCGCCGAGATTTCCGCCGGCGGGTCGGTCCATGTCTATGGAACGCTGCGCGGGCGCGCGATCGCGGGGATGGG
CGGCCAGCCGGGGGCGCGGATCTTCGCCACCGCGATGAAGGCGGAACTGCTGGCGATCGACGGCTATTACATGATCGCCG
AGGAGATCGATCCCGCCCTGAGCGGCCAGCCGGCGCAGGCCCTGCTGGAAGACGGCACCCTTGTCGTCCGGCCATTGCAT
TGA

Upstream 100 bases:

>100_bases
CACGCCCGGGAATTCGCACGGTCGGTCCACCGATCGCTCGACAGGGCGGGATTCTCACGGTAGCTGGAATGGGCCTCCAT
CATTCGCAGACCGAAGGTCC

Downstream 100 bases:

>100_bases
AGGGCCGCTTTCCCCGTTGCCCTCGCCATATCTCCGCCACTAGAGTCCCGCAAACATGACGCCGCAGAATGGCGAATCCG
GACAGAGGAACACGCGTATG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTPLSDDFRPPPRIRARGRSFLALVLSPEAGLDDWLRGLDAQIARSPSFFVGKPIILDLGLLSGEAEGLADLYPALLERG
VRIIGIEGGDSAWPALAGWDWPQGFEGGRASGTVALPEETDGGEAASATAPAASLIVERPVRSGQSVLHHDGDVIVIGSV
ASGAEISAGGSVHVYGTLRGRAIAGMGGQPGARIFATAMKAELLAIDGYYMIAEEIDPALSGQPAQALLEDGTLVVRPLH

Sequences:

>Translated_240_residues
MTPLSDDFRPPPRIRARGRSFLALVLSPEAGLDDWLRGLDAQIARSPSFFVGKPIILDLGLLSGEAEGLADLYPALLERG
VRIIGIEGGDSAWPALAGWDWPQGFEGGRASGTVALPEETDGGEAASATAPAASLIVERPVRSGQSVLHHDGDVIVIGSV
ASGAEISAGGSVHVYGTLRGRAIAGMGGQPGARIFATAMKAELLAIDGYYMIAEEIDPALSGQPAQALLEDGTLVVRPLH
>Mature_239_residues
TPLSDDFRPPPRIRARGRSFLALVLSPEAGLDDWLRGLDAQIARSPSFFVGKPIILDLGLLSGEAEGLADLYPALLERGV
RIIGIEGGDSAWPALAGWDWPQGFEGGRASGTVALPEETDGGEAASATAPAASLIVERPVRSGQSVLHHDGDVIVIGSVA
SGAEISAGGSVHVYGTLRGRAIAGMGGQPGARIFATAMKAELLAIDGYYMIAEEIDPALSGQPAQALLEDGTLVVRPLH

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=230, Percent_Identity=32.1739130434783, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 24881; Mature: 24749

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLSDDFRPPPRIRARGRSFLALVLSPEAGLDDWLRGLDAQIARSPSFFVGKPIILDLG
CCCCCCCCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
LLSGEAEGLADLYPALLERGVRIIGIEGGDSAWPALAGWDWPQGFEGGRASGTVALPEET
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
DGGEAASATAPAASLIVERPVRSGQSVLHHDGDVIVIGSVASGAEISAGGSVHVYGTLRG
CCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEECCCCEEEEEEEECC
RAIAGMGGQPGARIFATAMKAELLAIDGYYMIAEEIDPALSGQPAQALLEDGTLVVRPLH
EEEECCCCCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCCCHHHHHCCCCEEEEECC
>Mature Secondary Structure 
TPLSDDFRPPPRIRARGRSFLALVLSPEAGLDDWLRGLDAQIARSPSFFVGKPIILDLG
CCCCCCCCCCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
LLSGEAEGLADLYPALLERGVRIIGIEGGDSAWPALAGWDWPQGFEGGRASGTVALPEET
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
DGGEAASATAPAASLIVERPVRSGQSVLHHDGDVIVIGSVASGAEISAGGSVHVYGTLRG
CCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCEECCCCEEEEEEEECC
RAIAGMGGQPGARIFATAMKAELLAIDGYYMIAEEIDPALSGQPAQALLEDGTLVVRPLH
EEEECCCCCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCCCHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]