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The map label for this gene is hflX [H]

Identifier: 162148045

GI number: 162148045

Start: 2318702

End: 2319988

Strand: Reverse

Name: hflX [H]

Synonym: GDI_2261

Alternate gene names: 162148045

Gene position: 2319988-2318702 (Counterclockwise)

Preceding gene: 162148046

Following gene: 162148044

Centisome position: 58.82

GC content: 69.39

Gene sequence:

>1287_bases
GTGTCGCAATCCGCGACGCGGGCCGCCGTCATCCTGCCCTGGGAACGGCCGGACCGCCAGGAGGAAGTTCGGGCGGCCGA
GGCCCGACTGGAAGAAGCTGTCGGCCTCGCCGCCTCGATCGGCCTGGTCATCGTGCGCCAGGCCGTGCTGGTGCTGCGGG
CACGCCGGCCGTCGACATTGCTGGGAAACGGGCAGGTCGAATCGCTGCGCGCGGCGGTCCAGCAGGACCGCGTCGCCGTC
GTGATCGTCGATTCGCGCCTCTCCCCCGTGCAGCAGCGCAACCTGGAACGCGCCCTGGGCTGCAAGGTCATCGACCGTAC
GGCGCTGATCCTGGACATTTTCGGCGAGCGCGCGGCCACCAAGGAAGGCACGCTGCAGGTCGAACTGGCCCATCTGGAAT
ATCAGCGCAGCCGCCTGGTCCGGACCTGGACCCATCTGGAGCGCCAGCGCGGCGGCTTCGGCTTCCTGGGCGGTCCGGGC
GAAACCCAGATCGAGGCCGACCGCCGCATGATCGGCGACCGGATCGTGCGCCTGAAGCGGGAACTGGAACAGGTGCGGCG
CACGCGCGGCCTGCACCGCGCCGCGCGCCGGCGGGTGCCGTTTCCGGTCGTGGCGCTGGTCGGTTACACCAATGCCGGAA
AATCGACCCTGTTCAATGCCCTGACCGGGGCGACCGTCTTCGCCCAGGACCAGTTGTTCGCCACCCTCGACCCGACGATG
CGCGGCATTCGCCTGCCGTCGGGCCGGCGCATCATCCTGTCCGACACGGTGGGCTTCATCAGCGACCTGCCGACCGAACT
GATCGCCGCCTTCCGCGCGACGCTGGAAGAGGTCGCCGAGGCCGACGTCATCCTGCATGTGCGCGATATCTCCCATCCCG
ACAGCGCCGCCCAGCGCGCGGATGTCGAGGACGTGCTGGAAGGCATGGCCGGCAGCGGCACGCTGGAGGACGATTGGCGC
CGGCGCGTGATCGAGGTGCAGAACAAGGCCGACCTGATCGGCGGCCGCGATGCCGTGCCGCCCCGCAAGGGCAGCGTCGT
CATTTCGGCCATCACGGGCGAGGGCCTGCCCGACCTGCTGGCCGCCATCGATTCGCGCCTGACCGAGGCGATGGAAACCG
TCCGCTACACCATCCCGGTGAAGGACGGCGCCATGCTGGCGTGGCTGTACGCTCATGGCGAAGTGACATCGCGCGAGGAT
GGCGAGCAGGCTATCGTGGTGACGGTTCGCCTGTTGCCGGCCGACCGCGCCCGTTTCGAGATGCAGATCGCCGGTCAGGA
CCAGTAG

Upstream 100 bases:

>100_bases
ACGCCGGTGGTCCTGTTCGACCCGTCGCGCACCGAAGGCGCCACCGTTGACCTGACGGAGAAGGATCTGGCGGGGGATGC
CGATCTCCTCTGACGATCCC

Downstream 100 bases:

>100_bases
GGGTGCGGCCCGGCAGGGAGTGAAGATCATGACGGTCCCCGTTTCCGCCGGCCCTGTTTCCGTGGGACAGATGCGCGAGG
TGCTGGGGATCATGCGGCTG

Product: GTP-binding protein hflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSQSATRAAVILPWERPDRQEEVRAAEARLEEAVGLAASIGLVIVRQAVLVLRARRPSTLLGNGQVESLRAAVQQDRVAV
VIVDSRLSPVQQRNLERALGCKVIDRTALILDIFGERAATKEGTLQVELAHLEYQRSRLVRTWTHLERQRGGFGFLGGPG
ETQIEADRRMIGDRIVRLKRELEQVRRTRGLHRAARRRVPFPVVALVGYTNAGKSTLFNALTGATVFAQDQLFATLDPTM
RGIRLPSGRRIILSDTVGFISDLPTELIAAFRATLEEVAEADVILHVRDISHPDSAAQRADVEDVLEGMAGSGTLEDDWR
RRVIEVQNKADLIGGRDAVPPRKGSVVISAITGEGLPDLLAAIDSRLTEAMETVRYTIPVKDGAMLAWLYAHGEVTSRED
GEQAIVVTVRLLPADRARFEMQIAGQDQ

Sequences:

>Translated_428_residues
MSQSATRAAVILPWERPDRQEEVRAAEARLEEAVGLAASIGLVIVRQAVLVLRARRPSTLLGNGQVESLRAAVQQDRVAV
VIVDSRLSPVQQRNLERALGCKVIDRTALILDIFGERAATKEGTLQVELAHLEYQRSRLVRTWTHLERQRGGFGFLGGPG
ETQIEADRRMIGDRIVRLKRELEQVRRTRGLHRAARRRVPFPVVALVGYTNAGKSTLFNALTGATVFAQDQLFATLDPTM
RGIRLPSGRRIILSDTVGFISDLPTELIAAFRATLEEVAEADVILHVRDISHPDSAAQRADVEDVLEGMAGSGTLEDDWR
RRVIEVQNKADLIGGRDAVPPRKGSVVISAITGEGLPDLLAAIDSRLTEAMETVRYTIPVKDGAMLAWLYAHGEVTSRED
GEQAIVVTVRLLPADRARFEMQIAGQDQ
>Mature_427_residues
SQSATRAAVILPWERPDRQEEVRAAEARLEEAVGLAASIGLVIVRQAVLVLRARRPSTLLGNGQVESLRAAVQQDRVAVV
IVDSRLSPVQQRNLERALGCKVIDRTALILDIFGERAATKEGTLQVELAHLEYQRSRLVRTWTHLERQRGGFGFLGGPGE
TQIEADRRMIGDRIVRLKRELEQVRRTRGLHRAARRRVPFPVVALVGYTNAGKSTLFNALTGATVFAQDQLFATLDPTMR
GIRLPSGRRIILSDTVGFISDLPTELIAAFRATLEEVAEADVILHVRDISHPDSAAQRADVEDVLEGMAGSGTLEDDWRR
RVIEVQNKADLIGGRDAVPPRKGSVVISAITGEGLPDLLAAIDSRLTEAMETVRYTIPVKDGAMLAWLYAHGEVTSREDG
EQAIVVTVRLLPADRARFEMQIAGQDQ

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=261, Percent_Identity=40.2298850574713, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI310133116, Length=259, Percent_Identity=40.1544401544402, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI310124269, Length=240, Percent_Identity=41.25, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI310124267, Length=240, Percent_Identity=41.25, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI310124171, Length=240, Percent_Identity=41.25, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI310124169, Length=240, Percent_Identity=41.25, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI310117731, Length=115, Percent_Identity=37.3913043478261, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790615, Length=368, Percent_Identity=43.4782608695652, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=414, Percent_Identity=33.5748792270531, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24650079, Length=380, Percent_Identity=35.2631578947368, Blast_Score=158, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47139; Mature: 47007

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSATRAAVILPWERPDRQEEVRAAEARLEEAVGLAASIGLVIVRQAVLVLRARRPSTL
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LGNGQVESLRAAVQQDRVAVVIVDSRLSPVQQRNLERALGCKVIDRTALILDIFGERAAT
ECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KEGTLQVELAHLEYQRSRLVRTWTHLERQRGGFGFLGGPGETQIEADRRMIGDRIVRLKR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
ELEQVRRTRGLHRAARRRVPFPVVALVGYTNAGKSTLFNALTGATVFAQDQLFATLDPTM
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCCEEEECCCHH
RGIRLPSGRRIILSDTVGFISDLPTELIAAFRATLEEVAEADVILHVRDISHPDSAAQRA
HCEECCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHC
DVEDVLEGMAGSGTLEDDWRRRVIEVQNKADLIGGRDAVPPRKGSVVISAITGEGLPDLL
CHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEEECCCCHHHHH
AAIDSRLTEAMETVRYTIPVKDGAMLAWLYAHGEVTSREDGEQAIVVTVRLLPADRARFE
HHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCEEE
MQIAGQDQ
EEECCCCC
>Mature Secondary Structure 
SQSATRAAVILPWERPDRQEEVRAAEARLEEAVGLAASIGLVIVRQAVLVLRARRPSTL
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LGNGQVESLRAAVQQDRVAVVIVDSRLSPVQQRNLERALGCKVIDRTALILDIFGERAAT
ECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KEGTLQVELAHLEYQRSRLVRTWTHLERQRGGFGFLGGPGETQIEADRRMIGDRIVRLKR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHH
ELEQVRRTRGLHRAARRRVPFPVVALVGYTNAGKSTLFNALTGATVFAQDQLFATLDPTM
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCCEEEECCCHH
RGIRLPSGRRIILSDTVGFISDLPTELIAAFRATLEEVAEADVILHVRDISHPDSAAQRA
HCEECCCCCEEEEECCHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHC
DVEDVLEGMAGSGTLEDDWRRRVIEVQNKADLIGGRDAVPPRKGSVVISAITGEGLPDLL
CHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEEECCCCHHHHH
AAIDSRLTEAMETVRYTIPVKDGAMLAWLYAHGEVTSREDGEQAIVVTVRLLPADRARFE
HHHHHHHHHHHHHHEEEEEECCCCEEEEEEECCCCCCCCCCCEEEEEEEEECCCCCCEEE
MQIAGQDQ
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]