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The map label for this gene is frr

Identifier: 162147934

GI number: 162147934

Start: 2203358

End: 2203924

Strand: Reverse

Name: frr

Synonym: GDI_2150

Alternate gene names: 162147934

Gene position: 2203924-2203358 (Counterclockwise)

Preceding gene: 162147935

Following gene: 162147933

Centisome position: 55.88

GC content: 66.31

Gene sequence:

>567_bases
GTGGCTGCTGATCAGAAGACACTGCTGGATGACCTGACCCGTCGGATGGACGGCGCGCTGGAAAGCCTGCGCCGCGATTT
CGCGGGTCTGCGTTCGGGTCGCGCAAGTCCCGCGCTGATCGAACCGGTGCGTGTCGAGGCCTATGGCGGCGAGGTGCCGC
TGACGCAGGTCGGATCGATCGCGGTGCCCGAGGCGCGGATGCTGACCGTCCAGGTCTGGGACCGCTCGCTGGTGGGGGCG
GTCGAACGGGCGATTCGCGACAGCGGCCTGGGCCTGAATCCGGCGGCCGACGGCCAGACCGTGCGCGTGCCCATTCCCCA
GTTGACCGAGGAACGGCGCGGCGAACTGGCCCGCACGGCCGGGAAATATTCCGAAAACGCCAAGATCGCGGTGCGCGGCG
TGCGCCGCGACGGCATGGATCAGACCAAGGCGCAGGAAAAGAAGGGCGACATCAGCCAGGACGACGTCAAGGTGTGGTCG
GACGCGATCCAGAAGCTGACGGACCAGTATGTGAAGCGGATCGACGAGATGCTCGCGGAAAAGGAACGCGAGATCAAACA
GGTCTGA

Upstream 100 bases:

>100_bases
CCCGGATTGTCGAAACGGCCTGACGGGCCGGTTGCTGGAATGAATGAGGATAGGGGGCAGCCGTGACCGTGGCCCCCATG
GATGACTATGGAGGGCCGCT

Downstream 100 bases:

>100_bases
CGCGGCAGTGACCGTCAGTCCGGTGCCCGGCCCGCTGGCCGGGACGACAGCATCACTGGTCCCCCCGGCCACGACCGCGC
CCATTTCGGCGCCCGTGACG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAADQKTLLDDLTRRMDGALESLRRDFAGLRSGRASPALIEPVRVEAYGGEVPLTQVGSIAVPEARMLTVQVWDRSLVGA
VERAIRDSGLGLNPAADGQTVRVPIPQLTEERRGELARTAGKYSENAKIAVRGVRRDGMDQTKAQEKKGDISQDDVKVWS
DAIQKLTDQYVKRIDEMLAEKEREIKQV

Sequences:

>Translated_188_residues
MAADQKTLLDDLTRRMDGALESLRRDFAGLRSGRASPALIEPVRVEAYGGEVPLTQVGSIAVPEARMLTVQVWDRSLVGA
VERAIRDSGLGLNPAADGQTVRVPIPQLTEERRGELARTAGKYSENAKIAVRGVRRDGMDQTKAQEKKGDISQDDVKVWS
DAIQKLTDQYVKRIDEMLAEKEREIKQV
>Mature_187_residues
AADQKTLLDDLTRRMDGALESLRRDFAGLRSGRASPALIEPVRVEAYGGEVPLTQVGSIAVPEARMLTVQVWDRSLVGAV
ERAIRDSGLGLNPAADGQTVRVPIPQLTEERRGELARTAGKYSENAKIAVRGVRRDGMDQTKAQEKKGDISQDDVKVWSD
AIQKLTDQYVKRIDEMLAEKEREIKQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=29.7752808988764, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI291042689, Length=137, Percent_Identity=32.1167883211679, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786368, Length=174, Percent_Identity=45.9770114942529, Blast_Score=158, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24661488, Length=178, Percent_Identity=26.9662921348315, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_GLUDA (A9HKW6)

Other databases:

- EMBL:   AM889285
- EMBL:   CP001189
- RefSeq:   YP_001602395.1
- RefSeq:   YP_002274781.1
- ProteinModelPortal:   A9HKW6
- SMR:   A9HKW6
- GeneID:   5792509
- GeneID:   6973764
- GenomeReviews:   AM889285_GR
- GenomeReviews:   CP001189_GR
- KEGG:   gdj:Gdia_0370
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20798; Mature: 20667

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADQKTLLDDLTRRMDGALESLRRDFAGLRSGRASPALIEPVRVEAYGGEVPLTQVGSI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCE
AVPEARMLTVQVWDRSLVGAVERAIRDSGLGLNPAADGQTVRVPIPQLTEERRGELARTA
ECCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHH
GKYSENAKIAVRGVRRDGMDQTKAQEKKGDISQDDVKVWSDAIQKLTDQYVKRIDEMLAE
HCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEREIKQV
HHHHHHCC
>Mature Secondary Structure 
AADQKTLLDDLTRRMDGALESLRRDFAGLRSGRASPALIEPVRVEAYGGEVPLTQVGSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCE
AVPEARMLTVQVWDRSLVGAVERAIRDSGLGLNPAADGQTVRVPIPQLTEERRGELARTA
ECCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHH
GKYSENAKIAVRGVRRDGMDQTKAQEKKGDISQDDVKVWSDAIQKLTDQYVKRIDEMLAE
HCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEREIKQV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA