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The map label for this gene is gpsA [H]

Identifier: 162147857

GI number: 162147857

Start: 2117908

End: 2118870

Strand: Direct

Name: gpsA [H]

Synonym: GDI_2073

Alternate gene names: 162147857

Gene position: 2117908-2118870 (Clockwise)

Preceding gene: 162147856

Following gene: 162147860

Centisome position: 53.7

GC content: 72.38

Gene sequence:

>963_bases
ATGAACGCACCACGCATCGCCGTCATCGGGGCCGGCGCCTGGGGGATCGCCCTGGCGGTCCAGGCGGCCCGCGCGGGCGC
GCAGGTGCATCTGTGGGCCCGGAAACCGGACAGCCTGTCCGACACCCGCACCCTTCCCCGCCTGCCGCATGTGACCCTGC
CGGAATCGATCACCGTGACCGGCGACATGCCGGCCCGTGCCGACGCGGTGCTGCTGGCGGTGCCGATGCAGCATCTGCGC
GCCGTGCTGGGCCACGTGCCGCCGGCCGGACCGATGATCGCCTGCTGCAAGGGGGTGGAGCGCGACAGCCTGGCCCTGCC
GCTGGAGGTGATCGCCTCCCGTCATCCGAACCTTCCGCGCGCCGTGCTGTCCGGCCCCAATTTCGCGCATGAGGTGGCGC
AGGGCCTGCCGACGGCAGCGGTGCTGGCCTGCGAGGACCCGGTCGAGGCCCGGGATCTGGCCGACCATCTGACGACCCCG
GAATTCCGCCTGTATGCCAGCGACGACGCCATCGGGGTGCAGATCGGCGGCGCCGCGAAGAACGTGATCGCCATCGCCGC
CGGGGCCACGATCGGCGCGGGCCTGGGCGAAAACGCAAGGGCATCGCTGATGACGCGCGGCCTGGCGGAACTGGGCCGGC
TGTCGCGGGGTCTGGGTGGCCGCGCGGAAACGCTGTCGGGCCTGGCGGGCGTGGGCGACCTGATCCTGACCTGCACGGGC
CCGTCCTCGCGCAATTTCAGCCTGGGCCTGGCGCTGGGAAGGGGCGAAGCCCTGTCCGCGATCCTGGGCCAGCGCACCAC
GGTCGCCGAAGGCGTCACCACCGCCCCCGCCATCCTGGCCCTGGCCCGCAAACACGACATCAGCGTGCCGGTGATCGAAA
CGGTATCGCTGCTGCTGGCCGAGGACATCGACCTGGCCGAAGCCCGCGACCGGCTACTGAGCCGGCCCGTCGGGACGGAG
TGA

Upstream 100 bases:

>100_bases
CGCCCTTGCCCATCTGTCCCCGGATGGGACAGGAGAGGCAGCCGTCACGCGCATCGTCGAGGAATAGGCGCGGGGCGGGA
GGATAACGGGGGACAGGATC

Downstream 100 bases:

>100_bases
GCGGCCCGGCACCGACCGCGACAATCACGCCACTGGCGACATTCAGTTTCCGGTCCCGGACCCGGGCGTGCCGTTGCAGA
CACCATCCATGCAGGTCGCC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNAPRIAVIGAGAWGIALAVQAARAGAQVHLWARKPDSLSDTRTLPRLPHVTLPESITVTGDMPARADAVLLAVPMQHLR
AVLGHVPPAGPMIACCKGVERDSLALPLEVIASRHPNLPRAVLSGPNFAHEVAQGLPTAAVLACEDPVEARDLADHLTTP
EFRLYASDDAIGVQIGGAAKNVIAIAAGATIGAGLGENARASLMTRGLAELGRLSRGLGGRAETLSGLAGVGDLILTCTG
PSSRNFSLGLALGRGEALSAILGQRTTVAEGVTTAPAILALARKHDISVPVIETVSLLLAEDIDLAEARDRLLSRPVGTE

Sequences:

>Translated_320_residues
MNAPRIAVIGAGAWGIALAVQAARAGAQVHLWARKPDSLSDTRTLPRLPHVTLPESITVTGDMPARADAVLLAVPMQHLR
AVLGHVPPAGPMIACCKGVERDSLALPLEVIASRHPNLPRAVLSGPNFAHEVAQGLPTAAVLACEDPVEARDLADHLTTP
EFRLYASDDAIGVQIGGAAKNVIAIAAGATIGAGLGENARASLMTRGLAELGRLSRGLGGRAETLSGLAGVGDLILTCTG
PSSRNFSLGLALGRGEALSAILGQRTTVAEGVTTAPAILALARKHDISVPVIETVSLLLAEDIDLAEARDRLLSRPVGTE
>Mature_320_residues
MNAPRIAVIGAGAWGIALAVQAARAGAQVHLWARKPDSLSDTRTLPRLPHVTLPESITVTGDMPARADAVLLAVPMQHLR
AVLGHVPPAGPMIACCKGVERDSLALPLEVIASRHPNLPRAVLSGPNFAHEVAQGLPTAAVLACEDPVEARDLADHLTTP
EFRLYASDDAIGVQIGGAAKNVIAIAAGATIGAGLGENARASLMTRGLAELGRLSRGLGGRAETLSGLAGVGDLILTCTG
PSSRNFSLGLALGRGEALSAILGQRTTVAEGVTTAPAILALARKHDISVPVIETVSLLLAEDIDLAEARDRLLSRPVGTE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=279, Percent_Identity=29.0322580645161, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI24307999, Length=274, Percent_Identity=27.7372262773723, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1790037, Length=326, Percent_Identity=38.3435582822086, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32564399, Length=350, Percent_Identity=26.5714285714286, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=25.1396648044693, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=25.1396648044693, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17507425, Length=351, Percent_Identity=25.6410256410256, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210134, Length=323, Percent_Identity=25.6965944272446, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=355, Percent_Identity=26.7605633802817, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320181, Length=274, Percent_Identity=29.5620437956204, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI22026922, Length=289, Percent_Identity=28.3737024221453, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17136202, Length=271, Percent_Identity=29.8892988929889, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136204, Length=271, Percent_Identity=29.8892988929889, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136200, Length=271, Percent_Identity=29.8892988929889, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45551945, Length=235, Percent_Identity=25.1063829787234, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362270, Length=235, Percent_Identity=25.1063829787234, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 32870; Mature: 32870

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00957 NAD_G3PDH ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPRIAVIGAGAWGIALAVQAARAGAQVHLWARKPDSLSDTRTLPRLPHVTLPESITVT
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
GDMPARADAVLLAVPMQHLRAVLGHVPPAGPMIACCKGVERDSLALPLEVIASRHPNLPR
CCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHCCCCCCCH
AVLSGPNFAHEVAQGLPTAAVLACEDPVEARDLADHLTTPEFRLYASDDAIGVQIGGAAK
HHHCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCEEEEECCCCC
NVIAIAAGATIGAGLGENARASLMTRGLAELGRLSRGLGGRAETLSGLAGVGDLILTCTG
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECC
PSSRNFSLGLALGRGEALSAILGQRTTVAEGVTTAPAILALARKHDISVPVIETVSLLLA
CCCCCEEEEEEECCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
EDIDLAEARDRLLSRPVGTE
CCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNAPRIAVIGAGAWGIALAVQAARAGAQVHLWARKPDSLSDTRTLPRLPHVTLPESITVT
CCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEE
GDMPARADAVLLAVPMQHLRAVLGHVPPAGPMIACCKGVERDSLALPLEVIASRHPNLPR
CCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHCCCCCCCH
AVLSGPNFAHEVAQGLPTAAVLACEDPVEARDLADHLTTPEFRLYASDDAIGVQIGGAAK
HHHCCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCEEEEECCCCC
NVIAIAAGATIGAGLGENARASLMTRGLAELGRLSRGLGGRAETLSGLAGVGDLILTCTG
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECC
PSSRNFSLGLALGRGEALSAILGQRTTVAEGVTTAPAILALARKHDISVPVIETVSLLLA
CCCCCEEEEEEECCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH
EDIDLAEARDRLLSRPVGTE
CCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA