Click here to switch to the map view.

The map label for this gene is btuC [C]

Identifier: 162147845

GI number: 162147845

Start: 2105749

End: 2106864

Strand: Reverse

Name: btuC [C]

Synonym: GDI_2061

Alternate gene names: 162147845

Gene position: 2106864-2105749 (Counterclockwise)

Preceding gene: 162147846

Following gene: 162147844

Centisome position: 53.42

GC content: 68.82

Gene sequence:

>1116_bases
ATGACCGACACGACCCTGACGCGCCCCCGTGCGGTTCGTTCCGGGCCGGTCGATCCCGCCCTGCTGACGGCCGAGCGCGT
GCGGCATGTCCGGGATTCCTATCGTCACCTGCTGCGCCGCCGCAGCCTGATCCTGGCGGTGCTGACGGTACTGATCCTGA
TGTCGATGCTGCTGGATTTCGCGCTGGGACCGTCCGGCCTGTCGCCCGCGACCCTGCTGCGGGTCCTGCTGCATCCGCAC
GACGTCCCGGCCGGGCAGAGCGTCATCGTCTGGCAGATCCGCCTGCCGTACGCGCTGATGGCGGTGTGCGTCGGCGCGGC
GCTGGGCCTGTCCGGGGCCGAAATGCAGACGATCCTGAACAACCCGCTGGCCAGCCCGTTCACGCTCGGCGTATCGGCTG
CGGCGGCGTTCGGGGCGTCGCTGGCGATCGTCCTGCAATGGCAGATCCCGGGCGTGCCCGCTGAATGGGTCGTTTCGGCC
GATGCCTTCGCCTTCGCCATCGGTTCCGCCTTCCTGCTGGACCTGGTGTCCTGCCTGCGCGATGCCTCGACCAGCACCGT
GGTGCTGTTCGGCATCGCGCTGGTCTTCACCTTTCACGCCCTGGTCTCGCTGGTCCAGTTCGTGGCCAGCGAGGACGCGC
TGCAGGACCTGGTGTTCTGGACCATGGGCAGCCTGACCCGCTCGAACTGGAGCAAGGTGGGCATCCTGGCGTCGGTCTGC
GCCGTCATCCTGCCCCTGTCCTTTCGCTCGGCCTGGTCGCTGACCGCCCTGCGCATGGGTGAGGAACGGGCGGCCAGCTT
CGGCGTGGACGTACGCCGGGTACGCATCGGGTCGCTGCTGCGGATCAGCATCCTGTCGTCGCTGGCGGTGTCCTTCGTCG
GCACCATCGGCTTCGTGGGGCTGGTCGCCCCGCATATCGCCCGCGGCCTGCTGGGCGAGGACCATCGCTTCTACCTGCCC
GGCAGCGTCTTGGTCGGATGCCTGATCATGTCGCTGTCCTCGGTCGCGGCACGCAACGTGCTGCCGGGCGTCATCGTGCC
CGTGGGCATCGTCACCGCCCTGGTGGGCATTCCCTTCTTCCTGGCGATCGTGCTGCGCCGCCGGGTGGCATCATGA

Upstream 100 bases:

>100_bases
ACCTGTTCCGCGACGTCGATCCCGAAGCGACCCGGACCGAGCTTTACGCGCGCTTCCTGCCCGTTCCCAATAGCGGGACC
TACTGGGTGTCGGACACGCC

Downstream 100 bases:

>100_bases
GCGGCCTGACCGCTGCCCACGTCACGGTGCGCTATGGCCGCCGGACGGTGCTGGACGACCTTTCGGTCGGGCCGCTGCCG
GCCGGCCAGGTCTCGGCCCT

Product: vitamin B12 import system permease btuC

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTDTTLTRPRAVRSGPVDPALLTAERVRHVRDSYRHLLRRRSLILAVLTVLILMSMLLDFALGPSGLSPATLLRVLLHPH
DVPAGQSVIVWQIRLPYALMAVCVGAALGLSGAEMQTILNNPLASPFTLGVSAAAAFGASLAIVLQWQIPGVPAEWVVSA
DAFAFAIGSAFLLDLVSCLRDASTSTVVLFGIALVFTFHALVSLVQFVASEDALQDLVFWTMGSLTRSNWSKVGILASVC
AVILPLSFRSAWSLTALRMGEERAASFGVDVRRVRIGSLLRISILSSLAVSFVGTIGFVGLVAPHIARGLLGEDHRFYLP
GSVLVGCLIMSLSSVAARNVLPGVIVPVGIVTALVGIPFFLAIVLRRRVAS

Sequences:

>Translated_371_residues
MTDTTLTRPRAVRSGPVDPALLTAERVRHVRDSYRHLLRRRSLILAVLTVLILMSMLLDFALGPSGLSPATLLRVLLHPH
DVPAGQSVIVWQIRLPYALMAVCVGAALGLSGAEMQTILNNPLASPFTLGVSAAAAFGASLAIVLQWQIPGVPAEWVVSA
DAFAFAIGSAFLLDLVSCLRDASTSTVVLFGIALVFTFHALVSLVQFVASEDALQDLVFWTMGSLTRSNWSKVGILASVC
AVILPLSFRSAWSLTALRMGEERAASFGVDVRRVRIGSLLRISILSSLAVSFVGTIGFVGLVAPHIARGLLGEDHRFYLP
GSVLVGCLIMSLSSVAARNVLPGVIVPVGIVTALVGIPFFLAIVLRRRVAS
>Mature_370_residues
TDTTLTRPRAVRSGPVDPALLTAERVRHVRDSYRHLLRRRSLILAVLTVLILMSMLLDFALGPSGLSPATLLRVLLHPHD
VPAGQSVIVWQIRLPYALMAVCVGAALGLSGAEMQTILNNPLASPFTLGVSAAAAFGASLAIVLQWQIPGVPAEWVVSAD
AFAFAIGSAFLLDLVSCLRDASTSTVVLFGIALVFTFHALVSLVQFVASEDALQDLVFWTMGSLTRSNWSKVGILASVCA
VILPLSFRSAWSLTALRMGEERAASFGVDVRRVRIGSLLRISILSSLAVSFVGTIGFVGLVAPHIARGLLGEDHRFYLPG
SVLVGCLIMSLSSVAARNVLPGVIVPVGIVTALVGIPFFLAIVLRRRVAS

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=290, Percent_Identity=34.8275862068965, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788004, Length=293, Percent_Identity=34.8122866894198, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790741, Length=337, Percent_Identity=31.7507418397626, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786805, Length=287, Percent_Identity=34.1463414634146, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786347, Length=279, Percent_Identity=30.4659498207885, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786804, Length=287, Percent_Identity=29.616724738676, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39449; Mature: 39318

Theoretical pI: Translated: 10.97; Mature: 10.97

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTTLTRPRAVRSGPVDPALLTAERVRHVRDSYRHLLRRRSLILAVLTVLILMSMLLDF
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGPSGLSPATLLRVLLHPHDVPAGQSVIVWQIRLPYALMAVCVGAALGLSGAEMQTILN
HCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHC
NPLASPFTLGVSAAAAFGASLAIVLQWQIPGVPAEWVVSADAFAFAIGSAFLLDLVSCLR
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DASTSTVVLFGIALVFTFHALVSLVQFVASEDALQDLVFWTMGSLTRSNWSKVGILASVC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AVILPLSFRSAWSLTALRMGEERAASFGVDVRRVRIGSLLRISILSSLAVSFVGTIGFVG
HHHHHHCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAPHIARGLLGEDHRFYLPGSVLVGCLIMSLSSVAARNVLPGVIVPVGIVTALVGIPFF
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAIVLRRRVAS
HHHHHHHHHCC
>Mature Secondary Structure 
TDTTLTRPRAVRSGPVDPALLTAERVRHVRDSYRHLLRRRSLILAVLTVLILMSMLLDF
CCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGPSGLSPATLLRVLLHPHDVPAGQSVIVWQIRLPYALMAVCVGAALGLSGAEMQTILN
HCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHC
NPLASPFTLGVSAAAAFGASLAIVLQWQIPGVPAEWVVSADAFAFAIGSAFLLDLVSCLR
CCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DASTSTVVLFGIALVFTFHALVSLVQFVASEDALQDLVFWTMGSLTRSNWSKVGILASVC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AVILPLSFRSAWSLTALRMGEERAASFGVDVRRVRIGSLLRISILSSLAVSFVGTIGFVG
HHHHHHCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAPHIARGLLGEDHRFYLPGSVLVGCLIMSLSSVAARNVLPGVIVPVGIVTALVGIPFF
HHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LAIVLRRRVAS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]