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The map label for this gene is deoD [H]

Identifier: 162147839

GI number: 162147839

Start: 2099746

End: 2100624

Strand: Reverse

Name: deoD [H]

Synonym: GDI_2055

Alternate gene names: 162147839

Gene position: 2100624-2099746 (Counterclockwise)

Preceding gene: 162147840

Following gene: 162147837

Centisome position: 53.26

GC content: 68.37

Gene sequence:

>879_bases
GTGATCGAACCCGTCATCGGACTGATCGGCGGGTCCGGCCTGTATGACATCGACGGGCTGGAGGAAAAGGAATGGCGCAC
GGTGGAAACGCCGTGGGGCCTGCCGTCCGACCAACTCCTGTTCGGCCGGCTGGACGGAGTGCGCTGCGTGTTCCTGCCAC
GCCACGGGCGCGGGCACCCGATCCCGCCGTCGCGCCTGAACTACCGGGCGAACATCGCGGCGCTGAAGCAGTCGGGCGTG
ACCGACATCGTCTCGCTCTCGGCCGTGGGATCGCTGAAGGAGGAACTGCCGCCCGGGCATTTCGTCATCATCGACCAGTT
CATCGACCGGTCCTTCGCGCGGGAAAAGAGCTTCTTCGATACCGGATGCGTCGCCCATGTCTCGATGGCCGACCCGCTCT
GCCCGCGCATCGGCGACGCGCTGGAGGAAACCGCGCGCGGCCTGGGGCTGGACGTCACGCGGGGCGGGACGTACCTGGTG
ATGGAAGGCCCGCAATTCTCCACCCGGGCGGAAAGCAACCTCTACCGGTCCTGGGGCTGTTCGGTGGTCGGCATGACCAA
CATGCCCGAGGCGAAGCTGGCCCGCGAGGCCGAGATCTGTTACGCGACCGTCGCCATGGTGACGGACTACGATTGCTGGC
ACCCGGACCATGACAGCGTCACCGTGGATGCGGTGGTCAAGGTCATGCTGTCCAATGCCGATCGCGCCCGCGCGCTGGTC
AAATCCGTCATTCCGGCCCTGGGCAGCCCGCGCGGCCCGTGCCGTGCCGGCTGCGACAGGGCACTGGAACATGCGCTGAT
CACCGCGCCCGACCGCCGCGACCCGGCCCTGCTGGCGAAGCTGCAATCCGTCGCGGGCCGGGTGCTGGCGCGGGGCTGA

Upstream 100 bases:

>100_bases
ACGCTCTATCTTCTGTTCCTCGCCGTGCTGGCGTTCCTTCTCAAACGGAGAATCTGGTCCGATGTCCATTAATCCCGCAC
CCAGCCCGTCCGACGCGGAC

Downstream 100 bases:

>100_bases
TCCCGGCTAGAGGTTTTTTTCGAAGAAGGCCAGGCTGCGGGTCCGTGCCAGGGACGCGGCCTGGGCGTTGAAGCTGTCGC
GTTCCGAACAGCCGAACCCG

Product: 5'-methylthioadenosine phosphorylase

Products: NA

Alternate protein names: 5'-methylthioadenosine phosphorylase; MTA phosphorylase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MIEPVIGLIGGSGLYDIDGLEEKEWRTVETPWGLPSDQLLFGRLDGVRCVFLPRHGRGHPIPPSRLNYRANIAALKQSGV
TDIVSLSAVGSLKEELPPGHFVIIDQFIDRSFAREKSFFDTGCVAHVSMADPLCPRIGDALEETARGLGLDVTRGGTYLV
MEGPQFSTRAESNLYRSWGCSVVGMTNMPEAKLAREAEICYATVAMVTDYDCWHPDHDSVTVDAVVKVMLSNADRARALV
KSVIPALGSPRGPCRAGCDRALEHALITAPDRRDPALLAKLQSVAGRVLARG

Sequences:

>Translated_292_residues
MIEPVIGLIGGSGLYDIDGLEEKEWRTVETPWGLPSDQLLFGRLDGVRCVFLPRHGRGHPIPPSRLNYRANIAALKQSGV
TDIVSLSAVGSLKEELPPGHFVIIDQFIDRSFAREKSFFDTGCVAHVSMADPLCPRIGDALEETARGLGLDVTRGGTYLV
MEGPQFSTRAESNLYRSWGCSVVGMTNMPEAKLAREAEICYATVAMVTDYDCWHPDHDSVTVDAVVKVMLSNADRARALV
KSVIPALGSPRGPCRAGCDRALEHALITAPDRRDPALLAKLQSVAGRVLARG
>Mature_292_residues
MIEPVIGLIGGSGLYDIDGLEEKEWRTVETPWGLPSDQLLFGRLDGVRCVFLPRHGRGHPIPPSRLNYRANIAALKQSGV
TDIVSLSAVGSLKEELPPGHFVIIDQFIDRSFAREKSFFDTGCVAHVSMADPLCPRIGDALEETARGLGLDVTRGGTYLV
MEGPQFSTRAESNLYRSWGCSVVGMTNMPEAKLAREAEICYATVAMVTDYDCWHPDHDSVTVDAVVKVMLSNADRARALV
KSVIPALGSPRGPCRAGCDRALEHALITAPDRRDPALLAKLQSVAGRVLARG

Specific function: Catalyzes the formation of methylthio-D-ribose 1- phosphate (MTR-1-P) from methylthioadenosine (MTA) [H]

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=249, Percent_Identity=50.2008032128514, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71980569, Length=248, Percent_Identity=42.3387096774194, Blast_Score=197, Evalue=6e-51,
Organism=Saccharomyces cerevisiae, GI6323045, Length=259, Percent_Identity=37.4517374517375, Blast_Score=172, Evalue=6e-44,
Organism=Drosophila melanogaster, GI20130079, Length=244, Percent_Identity=41.8032786885246, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI221459247, Length=244, Percent_Identity=35.655737704918, Blast_Score=169, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.28 [H]

Molecular weight: Translated: 31665; Mature: 31665

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS01240 PNP_MTAP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEPVIGLIGGSGLYDIDGLEEKEWRTVETPWGLPSDQLLFGRLDGVRCVFLPRHGRGHP
CCCCEEEEECCCCEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCC
IPPSRLNYRANIAALKQSGVTDIVSLSAVGSLKEELPPGHFVIIDQFIDRSFAREKSFFD
CCCHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCC
TGCVAHVSMADPLCPRIGDALEETARGLGLDVTRGGTYLVMEGPQFSTRAESNLYRSWGC
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCC
SVVGMTNMPEAKLAREAEICYATVAMVTDYDCWHPDHDSVTVDAVVKVMLSNADRARALV
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHH
KSVIPALGSPRGPCRAGCDRALEHALITAPDRRDPALLAKLQSVAGRVLARG
HHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIEPVIGLIGGSGLYDIDGLEEKEWRTVETPWGLPSDQLLFGRLDGVRCVFLPRHGRGHP
CCCCEEEEECCCCEECCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEEEEECCCCCCC
IPPSRLNYRANIAALKQSGVTDIVSLSAVGSLKEELPPGHFVIIDQFIDRSFAREKSFFD
CCCHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCC
TGCVAHVSMADPLCPRIGDALEETARGLGLDVTRGGTYLVMEGPQFSTRAESNLYRSWGC
CCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCHHHHHHHHHHCC
SVVGMTNMPEAKLAREAEICYATVAMVTDYDCWHPDHDSVTVDAVVKVMLSNADRARALV
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHCCCHHHHHHH
KSVIPALGSPRGPCRAGCDRALEHALITAPDRRDPALLAKLQSVAGRVLARG
HHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA