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The map label for this gene is prmA [H]

Identifier: 162147773

GI number: 162147773

Start: 2022397

End: 2023302

Strand: Direct

Name: prmA [H]

Synonym: GDI_1989

Alternate gene names: 162147773

Gene position: 2022397-2023302 (Clockwise)

Preceding gene: 162147772

Following gene: 162147774

Centisome position: 51.28

GC content: 69.32

Gene sequence:

>906_bases
ATGACATCTCTGACCCGTCGGCATGCGACGGAACTGGAAACCATTGCCGTCACCGTCCCGGCCGAGGCCGTGATGGCGTA
CGAGGACGCGCTGTCGGTCGTCTGCACCACCATCGGCATTTTCGAACTGGATGACAGCCAGATCCTGTGGCGGGTCGAAG
GCGTACGCGATGTCGGCTACGGCGACAGCGAACTGACGGGTGCGCTGGCACTGGCCGCGACCGTGACCGGCCACGCGGCG
GAACTGGAACGCGTGCGGACCGAGGCCGAGGGCTGGCTGGCCCGGACCTATGATTCGTTTCCCGAACAGACGGTCGGGCG
GCGCTTCGTCGTGCGCGGCACGCATCTGGACGCCCCTGCCGCGTCACGCCGCATCGCCATCACGCTGGATGCCGGGATGG
CGTTCGGATCGGGCGAACATGGATCGACCCGGGGCTGCCTGCGGGCGCTGGAAAGCGTGGCGCATCGCCGCCCGCAGCGC
ATCCTGGACATGGGCTGCGGGTCGGGAATCCTGGCCATGGCGGCGGCGGCGCTGCTGCACCGCCCGGTACTGGCAGTCGA
TATCGAACCCTGGTCGGTGCGCACTACTGCGCAGAACGCGGCCCTGAACGGCCTGTCCGGACTGGTCACCGCGCGGCTGG
GCAATGGCTGGCGCACGCCCGGGCTGAAGCGGTATGCGCCGTTCGACCTGGTCTTCGCCAACATCCTGGCCCGCCCGCTC
TGCATGATGGCGCGGGACCTGGCCCTGAACCTGGCGCCTGGCGGCACCGCGATCCTGGCCGGACTGCTGAACAGCCAGGC
CGGGATGGTGCTGGCCGCCCACCGGCGCCAGGGCCTGGTACTGGAACGGCGCCTGACCGAAGGCGACTGGACGACCCTGG
TGCTGCGCAAGAGGACGACGACATGA

Upstream 100 bases:

>100_bases
GATACGGAACCATATCGTCCGTCGAGGGCAACCGGCTGGAAGTCGCGTTCGAGAAAGCCGGCCCGAAACGGGTCCTGGAT
ACATTTGTCGAGAAGATCCC

Downstream 100 bases:

>100_bases
CGGCGATCGCTTCCCGCCTCCCTGCCCTGCGGACCGTGCTGGGGCAGATGGACGTGGATGGTTTCATCCTGCTGCGCGGT
GACGAGCATCTGGGCGAATA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MTSLTRRHATELETIAVTVPAEAVMAYEDALSVVCTTIGIFELDDSQILWRVEGVRDVGYGDSELTGALALAATVTGHAA
ELERVRTEAEGWLARTYDSFPEQTVGRRFVVRGTHLDAPAASRRIAITLDAGMAFGSGEHGSTRGCLRALESVAHRRPQR
ILDMGCGSGILAMAAAALLHRPVLAVDIEPWSVRTTAQNAALNGLSGLVTARLGNGWRTPGLKRYAPFDLVFANILARPL
CMMARDLALNLAPGGTAILAGLLNSQAGMVLAAHRRQGLVLERRLTEGDWTTLVLRKRTTT

Sequences:

>Translated_301_residues
MTSLTRRHATELETIAVTVPAEAVMAYEDALSVVCTTIGIFELDDSQILWRVEGVRDVGYGDSELTGALALAATVTGHAA
ELERVRTEAEGWLARTYDSFPEQTVGRRFVVRGTHLDAPAASRRIAITLDAGMAFGSGEHGSTRGCLRALESVAHRRPQR
ILDMGCGSGILAMAAAALLHRPVLAVDIEPWSVRTTAQNAALNGLSGLVTARLGNGWRTPGLKRYAPFDLVFANILARPL
CMMARDLALNLAPGGTAILAGLLNSQAGMVLAAHRRQGLVLERRLTEGDWTTLVLRKRTTT
>Mature_300_residues
TSLTRRHATELETIAVTVPAEAVMAYEDALSVVCTTIGIFELDDSQILWRVEGVRDVGYGDSELTGALALAATVTGHAAE
LERVRTEAEGWLARTYDSFPEQTVGRRFVVRGTHLDAPAASRRIAITLDAGMAFGSGEHGSTRGCLRALESVAHRRPQRI
LDMGCGSGILAMAAAALLHRPVLAVDIEPWSVRTTAQNAALNGLSGLVTARLGNGWRTPGLKRYAPFDLVFANILARPLC
MMARDLALNLAPGGTAILAGLLNSQAGMVLAAHRRQGLVLERRLTEGDWTTLVLRKRTTT

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=222, Percent_Identity=31.5315315315315, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32320; Mature: 32188

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLTRRHATELETIAVTVPAEAVMAYEDALSVVCTTIGIFELDDSQILWRVEGVRDVGY
CCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCC
GDSELTGALALAATVTGHAAELERVRTEAEGWLARTYDSFPEQTVGRRFVVRGTHLDAPA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCC
ASRRIAITLDAGMAFGSGEHGSTRGCLRALESVAHRRPQRILDMGCGSGILAMAAAALLH
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHH
RPVLAVDIEPWSVRTTAQNAALNGLSGLVTARLGNGWRTPGLKRYAPFDLVFANILARPL
CCEEEEECCCCEEEEHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
CMMARDLALNLAPGGTAILAGLLNSQAGMVLAAHRRQGLVLERRLTEGDWTTLVLRKRTT
HHHHHHHHEEECCCHHHHHHHHHCCCCCEEEEECCCCCEEEEHHCCCCCEEEEEEEECCC
T
C
>Mature Secondary Structure 
TSLTRRHATELETIAVTVPAEAVMAYEDALSVVCTTIGIFELDDSQILWRVEGVRDVGY
CCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCC
GDSELTGALALAATVTGHAAELERVRTEAEGWLARTYDSFPEQTVGRRFVVRGTHLDAPA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEECCCCCCCC
ASRRIAITLDAGMAFGSGEHGSTRGCLRALESVAHRRPQRILDMGCGSGILAMAAAALLH
CCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHH
RPVLAVDIEPWSVRTTAQNAALNGLSGLVTARLGNGWRTPGLKRYAPFDLVFANILARPL
CCEEEEECCCCEEEEHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
CMMARDLALNLAPGGTAILAGLLNSQAGMVLAAHRRQGLVLERRLTEGDWTTLVLRKRTT
HHHHHHHHEEECCCHHHHHHHHHCCCCCEEEEECCCCCEEEEHHCCCCCEEEEEEEECCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]