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The map label for this gene is ubiG [H]

Identifier: 162147692

GI number: 162147692

Start: 1942877

End: 1943638

Strand: Reverse

Name: ubiG [H]

Synonym: GDI_1908

Alternate gene names: 162147692

Gene position: 1943638-1942877 (Counterclockwise)

Preceding gene: 162147696

Following gene: 162147686

Centisome position: 49.28

GC content: 71.26

Gene sequence:

>762_bases
ATGAATGTAAACGATTCGTCTTCTCGGGCGGCCCATCCAGCCGGGCATTCCGTCGCGCCGGACGAGATCGCGCGATTCAG
TGCCCTGGCGGACCGCTGGTGGGACCCTTCCGGGCCGATGCGGCCGCTGCACGCCATGAACGGCCTGCGCCTGGACTGGG
CCCGGCGCCACCTGCCCGCCCCCGGCACCCCCGGCGAGCCTGCCACCCGCCTGCTGGATATCGGCTGCGGCGCGGGCCTG
GCCAGCGAGGGCCTGGCCCGGATGGGCTATGACGTGACCGGGCTGGATGCCTCGGACGCCGCCATCGCCGCCGCGCGCGC
GCACCTGGCGGATCATCCCCTGCCCCCCGATGGCGGGTCCCTGGCCTATCGCGTCGGCAGCGCCGAGGAACTCCAGGCCG
AAGGGGCGCGATTCGCGGCCATCACGGCACTGGAAGTGATCGAGCACGTGACCGATCCCGCCGCGTTCCTGCGCGTGCTG
GCCGACATGGTGGCGCCGGGCGGGGTCATCATCGTCTCGACCCTGAACCGCACCCTGCGGTCGCTGGCGACGGCGAAGAT
CGGGGCGGAATACATCCTGCGCCTGCTGCCGGCCGGCACGCATGAATGGCGCAAGTTCATCACGCCCGCGGAACTGGGCG
CCTTCGCCAGCCAGGCCGGATTGCGCGTGTCCGACATCGCGGGAATGGTCCCCGCCCTGGGCGGCTGGCGCGAAAGCCAT
GACCTGGGCGTCAACTACATCGCCAGCCTGTCCGCTCCTTAA

Upstream 100 bases:

>100_bases
GCGCCGGACGGGGCATTGCGGTTATCTGCAAGGCGCGTCACATACCCTTCCACCGCTGCGCCGTCCAGCGGCAGATGGTC
AGCGGAAAGGTGGTGAAGCC

Downstream 100 bases:

>100_bases
CTGCGCTGACCAGCCGCCATAATTCAGTTTCGGTTCGGAAACGTGGGCTAGTGAGCGGGAGCGGAACGCAGTGGAGCGCA
GCAGACGCGCGTCGGATCGC

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNVNDSSSRAAHPAGHSVAPDEIARFSALADRWWDPSGPMRPLHAMNGLRLDWARRHLPAPGTPGEPATRLLDIGCGAGL
ASEGLARMGYDVTGLDASDAAIAAARAHLADHPLPPDGGSLAYRVGSAEELQAEGARFAAITALEVIEHVTDPAAFLRVL
ADMVAPGGVIIVSTLNRTLRSLATAKIGAEYILRLLPAGTHEWRKFITPAELGAFASQAGLRVSDIAGMVPALGGWRESH
DLGVNYIASLSAP

Sequences:

>Translated_253_residues
MNVNDSSSRAAHPAGHSVAPDEIARFSALADRWWDPSGPMRPLHAMNGLRLDWARRHLPAPGTPGEPATRLLDIGCGAGL
ASEGLARMGYDVTGLDASDAAIAAARAHLADHPLPPDGGSLAYRVGSAEELQAEGARFAAITALEVIEHVTDPAAFLRVL
ADMVAPGGVIIVSTLNRTLRSLATAKIGAEYILRLLPAGTHEWRKFITPAELGAFASQAGLRVSDIAGMVPALGGWRESH
DLGVNYIASLSAP
>Mature_253_residues
MNVNDSSSRAAHPAGHSVAPDEIARFSALADRWWDPSGPMRPLHAMNGLRLDWARRHLPAPGTPGEPATRLLDIGCGAGL
ASEGLARMGYDVTGLDASDAAIAAARAHLADHPLPPDGGSLAYRVGSAEELQAEGARFAAITALEVIEHVTDPAAFLRVL
ADMVAPGGVIIVSTLNRTLRSLATAKIGAEYILRLLPAGTHEWRKFITPAELGAFASQAGLRVSDIAGMVPALGGWRESH
DLGVNYIASLSAP

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=240, Percent_Identity=38.3333333333333, Blast_Score=167, Evalue=8e-42,
Organism=Escherichia coli, GI1788564, Length=238, Percent_Identity=38.655462184874, Blast_Score=165, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115533050, Length=232, Percent_Identity=36.2068965517241, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=279, Percent_Identity=29.7491039426523, Blast_Score=121, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24585589, Length=226, Percent_Identity=32.3008849557522, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281365311, Length=204, Percent_Identity=33.8235294117647, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26468; Mature: 26468

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVNDSSSRAAHPAGHSVAPDEIARFSALADRWWDPSGPMRPLHAMNGLRLDWARRHLPA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEHHHHHCCCC
PGTPGEPATRLLDIGCGAGLASEGLARMGYDVTGLDASDAAIAAARAHLADHPLPPDGGS
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LAYRVGSAEELQAEGARFAAITALEVIEHVTDPAAFLRVLADMVAPGGVIIVSTLNRTLR
EEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
SLATAKIGAEYILRLLPAGTHEWRKFITPAELGAFASQAGLRVSDIAGMVPALGGWRESH
HHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCH
DLGVNYIASLSAP
HCCHHHHHCCCCC
>Mature Secondary Structure
MNVNDSSSRAAHPAGHSVAPDEIARFSALADRWWDPSGPMRPLHAMNGLRLDWARRHLPA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEHHHHHCCCC
PGTPGEPATRLLDIGCGAGLASEGLARMGYDVTGLDASDAAIAAARAHLADHPLPPDGGS
CCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LAYRVGSAEELQAEGARFAAITALEVIEHVTDPAAFLRVLADMVAPGGVIIVSTLNRTLR
EEEECCCHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
SLATAKIGAEYILRLLPAGTHEWRKFITPAELGAFASQAGLRVSDIAGMVPALGGWRESH
HHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCH
DLGVNYIASLSAP
HCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA